Category Archives: Health/Life sciences

Postdoc in Mucosal Immunology

We are looking for 1-2 highly motivated postdoctoral fellows to join the Mucosal Immunology Group headed by Professor William Agace at the Division of Experimental and Translational Immunology, Department of Health Technology, Technical University of Denmark. The successful candidate will join a superb team of international researchers within the newly established NovoNordisk Foundation challenge grant-funded ‘Center for Intestinal Immune Regulation (CIIR)’. CIIR comprises of 4 collaborating teams (Agace, DTU; McCoy, Calgary (Canada); Bendtsen, Hvidovre hospital; Rønn-Larsen, DTU) whose combined expertise in mucosal immunology, gastroenterology, microbiota-host interactions, bioinformatics and state-of-the-art animal models aims to identify intestinal immune-stromal interactions important in intestinal homeostasis and in inflammatory bowel disease (IBD).  In joining you will be part of a highly vibrant and cross-disciplinary team of researchers at the international forefront of mucosal immunology research.

Responsibilities and qualifications
Your project is to identify immune-stromal interactions that are important for maintaining intestinal immune homeostasis and in the setting of inflammation promote immune mediated pathology. For this you will utilize state-of-the-art transgenic mouse models to modulate intestinal stromal-immune interactions and assess downstream consequences on intestinal homeostasis and disease (the latter using infection/inflammation models).  You will combine the above with scRNA-seq, CITE-seq, and spatial proteomics/transcriptomics analysis as well as in vitro co-culture techniques to perform mode of action studies. The project is multi-disciplinary and will involve close collaborations with participating bioinformaticians as well as researchers analyzing human intestinal immune compartments in health and IBD. The work is also expected to include some teaching and/or supervision of students within the laboratory.

You must hold a PhD degree or equivalent in immunology, be highly motivated, have the ability to work independently but also enjoy contributing and working within a team.  The successful candidates will have documented experience in mucosal immunology, working with transgenic animal models, mouse colony maintenance and in depth analysis of murine intestinal tissues including cell isolation, multi-color flow cytometry and cell sorting and intestinal disease models. Additional experience with spatial transcriptomics/proteomics scRNA-seq and organ cultures will be considered a merit.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.

The period of employment is 3 years full time with a starting date of 1 January 2023 (or according to mutual agreement). 

You can read more about career paths at DTU here

Further information
Further information please contact William Agace (wiag@dtu.dk).

Home page: Experimental and Translational Immunology research group

If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark.

Application procedure
Your complete online application must be submitted no later than 31 October 2022 (Danish time)Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • Application (cover letter)
  • CV
  • Academic Diplomas (MSc/PhD – in English)
  • List of publications
  • A one page summary documenting experiences/training of relevance to the job description

Applications received after the deadline will not be considered.

All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.

DTU Health Tech engages in research, education, and innovation base on technical and natural science for the healthcare sector. The Healthcare sector is a globally expanding market with demands for the most advanced technological solutions. DTU Health Tech creates the foundation for companies to develop new and innovative services and products which benefit people and create value for society. DTU Health Tech’s expertise spans from imaging and biosensor techniques, across digital health and biological modelling, to biopharma technologies. The department has a scientific staff of about 210 persons, 140 PhD students and a technical/administrative support staff of about 160 persons, of which a large majority contributes to our research infrastructure and related commercial activities.

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 13,400 students and 5,800 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

Deadline: 2022-10-31 at 23:59
Unit: DTU Health Tech

Read the job description at the university homepage or apply.

Post expires on Monday October 31st, 2022

Doctoral Researcher, Protein and Structural Biology, MSCA Doctoral Network project

The University of Oulu is part of the international scientific community producing new scientific knowledge and science-based solutions related to problems of the society. The University of Oulu is committed to educate future pioneers for building a more sustainable, intelligent and humane world. Creating new knowledge, taking responsibility and succeeding together are values that build a strong foundation for all our actions. We offer a working environment where individuals can cultivate their skills, do meaningful work, and develop professionally. The specialized research and service units of the University of Oulu enable extensive and diverse development and career opportunities for experts in various fields.

We are now looking for a motivated

Doctoral Researcher

to join our Marie Skłodowska-Curie Actions (MSCA) Doctoral Network project on developing more sustainable platforms for high-value recombinant protein production at the research unit of Protein and Structural Biology, Faculty of Biochemistry and Molecular Medicine.

Job description

The GreenerRPP project “Greener, more sustainable platforms for high-value recombinant protein production” is an MSCA Doctoral Network project coordinated by the University Medical Center Groningen (UMCG). The project will involve extensive collaborations between academic and industrial participants, based in 7 European countries, and it will be supported by Associated Partners in Europe and South-East Asia.

The challenge addressed in GreenerRPP is to markedly enhance the capacity for the production of secreted high-quality recombinant proteins, with a special emphasis on therapeutic proteins (biotherapeutics) and industrial enzymes that are difficult to express. The combined markets are in excess of $330 billion p.a., and the products are of massive significance for healthcare and a sustainable bio-based economy. GreenerRPP will address some of the most urgent outstanding problems associated with these industries.

(1) The project will address the rapidly-emerging issue of ‘sustainability’ in the biotechnology industry by focusing on improvements in yield and process design that markedly reduce the high current levels of waste, and by helping to deliver industrial enzymes that reduce energy and raw material costs in countless industrial and domestic settings.

(2) To achieve these objectives, we will develop powerful new microbial and mammalian cell platforms that can produce recombinant proteins in unparalleled quantity and quality. The consortium aims to develop a suite of super-producing platforms that bypass long-standing problems in protein production, and which can handle the enormous range of new-format biotherapeutics that are emerging.

(3) A comprehensive training programme will equip GreenerRPP Doctoral Researchers with the interdisciplinary and intersectoral skills required to succeed in these industries. A structured training plan, carried out in full accordance with the current Marie Skłodowska-Curie actions guidelines on supervision will provide the depth and breadth of training needed for Doctoral Researchers to excel in the biotechnology industry.

(4) The programme addresses the reality that recombinant protein production is largely carried out in (or outsourced by) high-income countries, and that the cost and questionable availability of many key products places low/middle income countries at a massive disadvantage. Therefore, this project incorporates a series of South East Asian Institutions as Associated Partners, and we will develop a global network with an extensive knowledge exchange.

GreenerRPP offers a challenging doctoral research training programme of 3 years, which is to be completed with a PhD thesis. All participating groups in GreenerRPP have excellent infrastructure, are well-equipped with state-of-the-art technologies, are highly experienced in the training of doctoral researchers, and promote equal gender opportunities. In addition to hands-on training in multidisciplinary and intersectoral research, we offer extensive transferable skills training through network-wide training events. Each doctoral researcher will undertake a 3-months intersectoral secondment with one of the other recruiting organizations or the Associated Partners.

Specifically, this doctoral researcher position involves the development of new and improved methods to secrete folded proteins from E. coli. The aim is to adapt the Tat secretion pathway combined with the CyDisCo system for oxidative folding in the cytoplasm to deliver g/L yields of high-quality disulphide bond-containing proteins to the periplasm and subsequently the fermentation broth. Identification of the limiting steps by systematic screening of each component/mechanistic step and subsequent optimization of each step individually and holistically will allow the widest possible applicability to other proteins.

Required qualifications

We are looking for excellent applicants with a MSc degree in biochemistry, biotechnology, molecular biology, microbiology, functional genomics, bioinformatics, systems biology, or computational biology.

Proficiency in English is a strict requirement.

The successful MSCA candidate must meet the MSCA criteria:

– Early Stage Researcher: Be in the first four years (full-time equivalent) of their research careers and not yet have been awarded a doctorate. This 4-year period is measured from the date of obtaining the degree which would formally entitle them to embark on a doctorate, excluding military, parental, sick leave, etc.

– Mobility Rule: Applicants can be of any nationality and must not have resided or carried out their main activity (work, studies, etc.) in Finlandfor more than 12 months in the last 3 years immediately before the recruitment date.

Position and salary

The fixed-term position for three years is available starting 1st March 2023 at the earliest. A six-month trial period is applied in the position.

The salary consists of a generous living allowance, mobility allowance and family allowance (if applicable) as determined by European Commission for Marie Skłodowska-Curie Actions guidelines. 

How to apply

Applications, together with all relevant enclosures, should be submitted using the electronic application form by October 30th, 2022 (23:59 Finnish local time). The application should be written in English and include the following:

1)      A motivation letter (max. 2 pages) summarizing applicant’s professional experience and expertise and describing why applicant is interested in this position. Also, information on personal research interests, experience and career plans are valuable to provide here

2)      Curriculum vitae (max. 4 pages) according to the instructions by the Finnish Advisory Board on Research Integrity https://tenk.fi/en/advice-and-materials/template-researchers-curriculum-vitae 

3)      Certificates/Diplomas Scanned copy of the original relevant (BSc/MSc) degree certificates and transcript of records and, when necessary, official translations to Finnish or English

4)      List of publications, if applicable

5)      Two letters of recommendation 

Only applications containing all relevant appendices and submitted through the online recruitment system will be considered. Top eligible candidates will be invited for an online interview. Short-listed candidates will be invited for a recruitment symposium to be organized soon after the recruitment process, for which travel costs and accommodation will be reimbursed.

Further information

For further information, please contact Dr. Mirva Saaranen mirva.saaranen@oulu.fi and Prof. Lloyd Ruddock lloyd.ruddock@oulu.fi

About Oulu, Finland
Finland is one of the most livable countries in the world, with a high quality of life, safety, excellent education system, and competitive economy. The Oulu region is home to over 200 000 people making it the largest urban centre in the Nordics and one of the fastest growing regions in northern Finland. Oulu is a combination of beautiful, northern nature, vivid cultural life and modern technology. Oulu is also known for its highly-educated people and friendly, easy-going atmosphere. Living in Oulu is easy – everything is only max. 20 minutes away! Find out more about Oulu: https://www.oulu.fi/university/living-in-oulu

Apply for the job

Read the job description at the university homepage

Post expires on Sunday October 30th, 2022

Postdoctoral position in comparative cancer genetics in dogs

About the position

The Norwegian University of Life Sciences (NMBU), Faculty of Veterinary Medicine has a vacant 3-year Postdoctoral fellow position in comparative cancer genetic research (mammary gland/breast cancer) in dogs. The successful candidate will be included in the research group of medical genetics in the Department of Preclinical Sciences and Pathology.

The position is part of a 4-year project «Multiple breast malignancies in dogs; improved understanding of disease progression by human-canine comparison” funded by the Research Council of Norway and NMBU. The project is in close collaboration with Institute of Cancer Research at Oslo University Hospital. The postdoctoral fellow will participate in a larger research group working on mammary gland tumors in dogs and be concerned with comparative aspects between dogs and humans.

Main tasks

  • Bioinformatic analysis including mutation analysis (germline/somatic), expression analysis, whole genome sequence analysis, GWAS, candidate gene analysis, comparative DNA/RNA-analysis, study of potential regulatory elements.
  • Participate in practical molecular analysis including PCR, sequencing, detection of genetic variants, expression analysis, molecular subclassification, in situ hybridization, cellular microenvironment, development/implementation of necessary methods.
  • The candidate will play an important role in shaping the direction of the project both concerning molecular genetic techniques and bioinformatic methods.

The main purpose of the postdoctoral position is to qualify for work in high-level scientific positions.

NMBUVeterinær smådyr

Competence

Required qualifications

  • PhD in bioinformatics or molecular biology. Candidates with PhD in medicine/veterinary medicine with good skills in bioinformatics may be considered. (PhD from abroad need to be official accepted/equal to Norwegian PhD).
  • Experience in bioinformatics and molecular genetics.
  • Good capabilities in both the spoken and written English language
  • Good IKT-skills.

The following experiences and skills will be emphasized:

  • Good experience with data-analysis /software in bioinformatics, including R-programming.
  • Experience in cell biology/cancer research.
  • Experience in laboratory work, cell biology, molecular biology.
  • Experience with supervision/teaching.
  • Experience in professional writing of papers.
  • Good capabilities in both the spoken and written Norwegian or Scandinavian language.

You need to:

  • Be able to work independently and in groups.
  • Be flexible and be able to do some of the work in the laboratory facilities at Oslo University Hospital (Oslo), when necessary.
  • Have good communication skills.
  • Have a strong professional motivation
  • Have good technical understanding and enjoy bioinformatic work as well as laboratory work.
  • Be patient and work accurately.

Remuneration and further information

The position is placed in government pay scale position code 1352 Postdoctoral Fellow, salary grade 61-77 (NOK 563.500-765.600), depending on qualifications. The position follows ordinary meriting regulations.

For further information, please contact professor Frode Lingaas, phone +47 67232010, e-mail: frode.lingaas@nmbu.no

 general information to applicants

NMBU

Studenter i veterinærbygningen

Application

To apply online for this vacancy, please click on the ‘Apply for this job’ button above. This will route you to the University’s Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Application deadline: 14.10.2022

Up to ten publications selected by the applicant as most relevant must be attached to the application. If it is difficult to identify the contribution of the applicant in multiple-author publications, a short explanation about the applicant’s part of the work is suggested.

Printed material which cannot be sent electronically should be sent by surface mail to Norwegian University of Life Sciences, Faculty of Veterinary medicine P.O. Box 5003, NO-1432 Ås, within deadline. Please quote reference number 22/04440

Applicants invited for an interview will be asked to present verified copies of diplomas and certificates.

About the Faculty of Veterinary Medicine

The Faculty of Veterinary Medicine at NMBU is the country’s only veterinary professional education and provide expertise in veterinary medicine and veterinary public health. The Faculty educates veterinarians, animal nurses and doctoral students in Veterinary Science and researches in veterinary medicine and related biomedical fields. We have 500 students and 430 employees.

The faculty consists of the departments of Preclinical Sciences and Pathology, Paraclinical Sciences, Production Animal Clinical Sciences and Companion Animal Clinical Sciences. We also run the Animal Hospital, which is closely linked to our research and education, and receives patients from all over the country.

NMBUVeterinærbygningen med Ur-bygning i bakgrunn

The Norwegian University of Life Sciences (NMBU)

NMBU has a particular responsibility for research and education that secures the basis for the life of future generations. Sustainability is rooted in everything we do and we deliver knowledge for life. NMBU has 1,900 employees of which about 500 phd scholarships and 6,700 students. The university is divided into seven faculties.

NMBU believes that a good working environment is characterised by diversity.

We encourage qualified candidates to apply regardless of gender, functional ability, cultural background or whether you have been outside the labour market for a period. If necessary, workplace adaptations will be made for persons with disabilities. More information about NMBU is available at www.nmbu.no.


 Read the job description at the university homepage

Apply for this job

Deadline

14th October 2022

Post expires on Friday October 14th, 2022

PhD Student in primary forest research (PA2022/3013)

Lund University, Department of Physical Geograhy and Ecosystem Science

Lund University was founded in 1666 and is repeatedly ranked among the world’s top 100 universities. The University has around 44 000 students and more than 8 000 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition.

Lund University welcomes applicants with diverse backgrounds and experiences. We regard gender equality and diversity as a strength and an asset.

States and changes in European primary forests
Few primary forests remain in Europe and we know surprisingly little about those that do. Even the locations of many of them has been a mystery. This PhD project aims to study primary forests to answer some of the following questions:

  • Do primary forests store more or less C in vegetation, dead wood and soil than managed forests do?
  • Are primary forest states changing over time due to global environmental change?
  • Are primary forests more or less stable during drought and heat waves compared to managed forests?
  • Has mortality and disturbances increased or decreased in primary forests over recent decades and are such changes different from managed forests?

This project will combine fieldwork with analysis of forest inventory and remote sensing data to contribute to answering these broader questions.

Motivation and background
Primary forests have many names, including pristine forests and virgin forests. They are characterized by little to no direct human impact, mainly the lack of logging. Humans use more than 75% of ice-free land globally, and pristine ecosystems have been transformed to crop lands, pastures and managed forests. Mapping, measuring and studying primary forests serves two purposes:

(1) Whilst we can increasingly detect changes in forest productivity, biomass and even mortality from space, the lack of precise land use maps means that it has been hard to determine what is natural dynamics and what is human intervention (e.g. logging, fertilization, planting). Primary forests are ideal sites to study natural processes since they are defined by little to no past and present direct human impact.

(2) How much carbon pristine forests store or the biodiversity they harbor, can be used to estimate how human land use has affected land carbon storage and biodiversity. Acquiring maps, knowledge and understanding of primary forests in a timely manner is key since old growth forests are being logged and lost at a high rate in Europe and globally. The states of primary forests are also informative for the states that could be reached when restoring ecosystems through free development protection or re-wilding.

Work duties
The project offers great flexibility and opportunities for a motivated candidate, the focus of the project can be shifted between three main parts, depending on the interests/skills of the candidate.

(1) Mapping and estimation of carbon storage in European primary forests. The estimation of carbon storage will combine sampling performed in the project with previous inventory work by this group in primary forests.

Questions: Do primary forests store more or less C in vegetation, dead wood and soil than managed forests do? Is the uptake of C over time positive or negative?, higher or lower in primary forests compared to managed forests?(2) Remote sensing of trends and changes in primary forests since the early 1980s. The focus here would be on changes in greenness or mortality and disturbances over time.

Questions: Have primary forests become greener since the 1980s? If so, more or less than comparable managed forests? Are primary forests more or less stable during drought and heat waves compared to managed forests? Has mortality and disturbances increased or decreased in primary forests over recent decades?

(3) Contribute to the establishment and study of a new long-term ecosystem monitoring network in primary forests.

In general the main duties of doctoral students are to devote themselves to their research studies which includes participating in research projects and third cycle courses. The work duties can also include teaching and other departmental duties (no more than 20%).

Admission requirements
A person meets the general admission requirements for third-cycle courses and study programmes if he or she:

  • has been awarded a second-cycle qualification, or
  • has satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the second cycle, or
  • has acquired substantially equivalent knowledge in some other way in Sweden or abroad.

Additional requirements:

The applicants are expected to hold a university degree (preferably MSc. or equivalent) in natural sciences. A degree in subjects like Physical Geography, Earth System Science, Environmental Sciences, Ecology or similar is preferable.

Assessment criteria
Selection for third-cycle studies is based on the student’s potential to profit from such studies. The assessment of potential is made primarily on the basis of academic results from the first and second cycle. Special attention is paid to the following:

  1. Knowledge and skills relevant to the thesis project and the subject of study.
  2. An assessment of ability to work independently and to formulate and tackle research problems.
  3. Written and oral communication skills
  4. Other experience relevant to the third-cycle studies, e.g. professional experience.
  5. Very good oral and written proficiency in English.
  6. Documented experience in field studies is an advantage.
  7. Experience of scientific publication in English is an asset.
  8. Documented experience of all or some of the following methods; field carbon inventory, mapping, remote sensing or statistical modelling.
  9. Experience in programming and tools for spatial statistics, geographical information systems and remote sensing.
  10. Experience in working in remote locations.
  11. Experience in applying for and acquiring external funding.
  12. Experience and ability to work individually and organise an individual schedule to fulfill a specific goal.
  13. Experience in working in and leading a team.
  14. Interest in working internationally, which may include visits at international collaborators.
  15. Be able to provide the name and contact information to three references.

Consideration will also be given to good collaborative skills, drive and independence, and how the applicant, through his or her experience and skills, is deemed to have the abilities necessary for successfully completing the third cycle programme.

Terms of employment
Only those admitted to third cycle studies may be appointed to a doctoral studentship. Doctoral studentships are regulated in the Higher Education Ordinance (1993:100), chapter 5, 1-7 §§.

Instructions on how to apply
Applications shall be written in English and include a 1 page maximum cover letter stating the reasons why you are interested in the position and in what way the research project corresponds to your interests and educational background. The application must also contain a CV, degree certificate or equivalent, and other documents you wish to be considered (grade transcripts, contact information for your references, letters of recommendation, etc.). It is appreciated if the application contains a link or otherwise to an accessible copy of a master thesis and other scientific work of the applicant, and the contact iunformation to three referenses.

Type of employment Temporary position longer than 6 months
First day of employment According to agreement
Salary Monthly salary
Number of positions 1
Working hours 100
City Lund
County Skåne län
Country Sweden
Reference number PA2022/3013
Contact
  • Anders Ahlström, anders.ahlstrom@nateko.lu.se,+46732028487
Union representative
  • OFR/ST:Fackförbundet ST:s kansli, 046-2229362
  • SACO:Saco-s-rådet vid Lunds universitet, 046-2229364
  • SEKO: Seko Civil, 046-2229366
Last application date 20.Oct.2022 11:59 PM CEST

Deadline: 2022-10-20 at 23:59
Unit: Department of Physical Geograhy and Ecosystem Science, Faculty of Science

Read the job description at the university homepage or apply.

Post expires on Thursday October 20th, 2022

PhD fellowship in Metabolite Receptology, SUNCR1 and Liver Pathology

We are offering a PhD fellowship in Metabolite Receptology, SUNCR1 and Liver Pathology commencing 1 January 2023 or after agreement.

About us
The Novo Nordisk Foundation Center for Basic Metabolic Research’s vision is to strengthen interdisciplinary research that transforms our basic understanding of the mechanisms that underlie metabolic health and disease, and to accelerate this knowledge toward new prevention and treatment strategies. We were established in 2010 and in 2017, we moved into new laboratories, offices, and meeting rooms in the Maersk Tower www.maersktower.ku.dk.

The Center has around 260 employees who work in an international, highly collaborative research environment across a range of biomedical disciplines. You can read more about us here: www.cbmr.ku.dk.

The Group
The aim of the Schwartz Group is to characterize and understand how signaling metabolites and their specific GPCR sensors interact with hormonal and neuronal mechanisms to control endocrine and metabolic functions as the basis for developing novel means to prevent and treat obesity and diabetes and related diseases. More information about the group can be found here.

Project description
We are seeking an enthusiastic, passionate PhD fellow to investigate the role of metabolite receptors – in particular the succinate receptor SUCNR1 – in hepatic response to metabolic stress and how this is a balance between protective repair and damaging inflammation. A special focus will be on characterizing the development of hepatic crown-like structures and their role in these processes. The project will involve a number of in vivo animal experiments and analysis of both murine and human tissue using various methods including state of the art histological methodologies involving different forms of spatial transcriptomic analysis combined with single cell transcriptomics analysis. The PhD project will be integrated in a portfolio of similar projects dealing with the role of metabolite receptors in repair, remodeling, and inflammation in other tissues a well as in cancer development.

Principal supervisor is Professor Thue W. Schwartz, Novo Nordisk Foundation Center for Basic Metabolic Research, E-mail: tws@sund.ku.dk

Start: 1 January 2023 or after agreement

Duration: 3 years as a PhD student

Job description
Your key tasks as a PhD student at SUND are:

  • Carry through an independent research project under supervision
  • Complete PhD courses or other equivalent education corresponding to approx. 30 ECTS points
  • Participate in active research environments including a stay at another research team
  • Write a PhD thesis on the grounds of your project
  • Investigate immune cell infiltration and polarization in liver during the metabolic dysfunction
  • Exploring the role of SUCNR1 in pathology progression and hepatic crown-like structure formation
  • Analyze immune cell architecture of hepatic crow-like structures using HiPlex RNAscope
  • Make molecular interpretation of data and communicate the results both nationally and internationally
  • Working both individually and together with collaborators across multiple scientific fields focused on improving our molecular understanding of immune cells and their role in metabolic disfunction.

Key criteria for the assessment of applicants

  • Must have a master degree in Human Biology, Molecular Biomedicine or equivalent
  • Expertise within GPCRs is a must and extensive experience with metabolic stress liver diseases preferable
  • Professional qualifications relevant to the PhD program including hands-on experience with histology, IHC, RNAscope technology, tissue clarity, microscopy and image analysis
  • Hands-on experience with western blotting, RT-qPCR, etc.
  • Practical skills in performing of animal experiments
  • FELASA ABD Certificate for in vivo mouse work
  • Ability and enthusiasm to learn new methods and techniques
  • Good communication skills in English, both oral and written (Danish is also preferred)
  • Highly ambitious and self-driven
  • Strong work ethics and team player mentality
  • Previously demonstrated a capacity for excellence, either during master’s degree or publications

The preferred applicant will possess an excellent academic track record and be highly motivated to perform science to extract novel findings of importance to SUCNR1 activation in immune responses and metabolic disfunction. We are particularly interested in candidates already familiar with the metabolism field, especially nutrient sensing and metabolic receptology.

Place of employment
The place of employment is the Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories, bioinformatics and statistic guidance, and access to big data from multiple cohorts.

Terms of employment
The employment as PhD fellow is full time and for 3 years. The starting date is 1 January 2023, or after agreement.

It is conditioned upon the applicant’s success­ful enrolment as a PhD student at the Graduate School at the Faculty of Health and Medical Sciences, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant.

The PhD study must be completed in accordance with The Ministerial Order on the PhD programme (2013) and the Faculty’s rules on achieving the degree. Salary, pension and terms of employment are in accordance with the agree­ment between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary begins around 28,400 DKK /approx. 3,818 EUR (October 2022-level) plus pension.

Questions
For specific information about the PhD fellowship, please contact the principal supervisor.

General information about PhD study at the Faculty of Health and Medical Sciences is available at the Graduate School’s website: https://healthsciences.ku.dk/phd/guidelines/

Application
Your application in English should include:

  • Letter of application addressing the requirements (max. one page).
  • CV incl. education, experience, language skills and other skills relevant for the position
  • Certified copy of original Master of Science diploma and transcript of records in the original language, including an authorized English translation if issued in other language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted.
    As a prerequisite for a PhD fellowship employment, your master’s degree must be equivalent to a Danish master’s degree. We encourage you to read more in the assessment database: https://ufm.dk/en/education/recognition-and-transparency/find-assessments/assessment-database. Please note that we might ask you to obtain an assessment of your education performed by the Ministry of Higher Education and Science.
    Applicants with a Master´s degree from abroad should also enclose a short description of the grading scale used
  • Publication list (if possible)
  • Other information to consider: References and recommendations (if possible)

Please submit your application by clicking on “Apply Now” below. Only online applications will be accepted.

Application deadline:  3 October 2022, 23.59pm CET
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.

The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement.

Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

The University of Copenhagen wishes to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.

Deadline: 2022-10-03 at 23:59
Unit: Faculty of Health and Medical Sciences

Read the job description at the university homepage or apply.

Post expires on Monday October 3rd, 2022

PhD scholarship within fish ecology and alpine aquatic community ecology

About the position

Faculty of Environmental Sciences and Natural Resource Management (MINA) at Norwegian University of Life Sciences (NMBU), has a vacant 3-year PhD position related to salmonid species in alpine lakes (Canada).

The main objectives of this PhD project: 1) understanding and quantifying baseline status of these ecosystems and 2) identifying the processes that are the most susceptible to alter this baseline in response to global climate change. In order to meet these objectives, we will sample the food-web of alpine lakes during the winter and summer, during three years in the Chic-Chocs mountains of Quebec, Canada. This project will adopt an approach at the nexus of biogeochemistry and community ecology to better describe and understand these unique ecosystems, with an emphasis on three salmonid species (e.i., Arctic charr, brook charr and lake trout). Winter conditions are poorly understood factors that may determine summertime characteristics, resulting in cascading effects between seasons and food webs (e.g., phytoplankton, zooplankton, and fish).

The candidate will have access to a wide range of data – habitat use and diet (isotopes and fatty acids and acoustic telemetry data) and growth (juvenile and adult growth rate based on back-calculated otoliths), and their expressions at different scales of intra- and interspecific competition and through different environmental conditions (seasons and years).

The research conducted in this position will be closely linked to a key task of the recently established knowledge hub from the Canadian Mountain Network (https://www.canadianmountainnetwork.ca/fr/research/knowledge-hubs/developing-knowledge-of-aquatic-realities-in-chic-choc-mountains), where NMBU is the co-leader of this network.

The applicant is made aware that an application for a PhD position at NMBU is at the same time an application for admission to a PhD programme at the institution. The documentation that is necessary to ensure that the admission requirements are met must be uploaded as an attachment.

Main tasks

  •  To study cascading effects of winter conditions on fish population dynamics and through the food-webs: top-down, bottom-up, and feedback loops
  • Conduct field work in alpine lakes in the Chic-Chocs (Canada).
  • Use a wide range of data, from telemetry (e.g., habitat use) growth, isotopes and fatty acids of three salmonid species, to food-web components.
  • Collaborate closely with other students and researchers in the fields of fish ecology, limnology, geochemistry, biogeochemistry, and genomics.
  • The specific tasks will be adjusted to the candidate’s interest and background.

The successful candidate is expected to enter a plan for the progress of the work towards a PhD degree during the first months of the appointment, with a view to completing a doctorate within the PhD scholarship period.

Laks

Competence

The successful applicant must meet the conditions defined for admission to a PhD programme at NMBU. The applicant must have an academically relevant education corresponding to a five-year Norwegian degree programme, where 120 credits are at master’s degree level. The applicant must have a documented strong academic background from previous studies and be able to document proficiency in both written and oral English. For more detailed information on the admission criteria please see the PhD Regulations and the relevant PhD programme description.

The applicant must document expertise and interest in the research subject.

Required Academic qualifications:

  • Master’s degree in a relevant scientific field, such as fish ecology, aquatic ecology, or environmental science. Preferably obtained within the last 5 years.

The following experiences and skills will be advantageous:

  • Experience with aquatic field work.
  • Knowledge of telemetry is a strong asset.
  • Familiarity with alpine limnology and fish population dynamic.
  • Scientific publications within related subjects.
  • Experience from field work in remote locations.
  • Knowledge of statistics and R

You need to:

  • be solution-oriented and possess the ability for independent work displaying initiative and careful thought.
  • have an analytical and academic approach to research questions.
  • have good collaborative/social skills.
  • have a keen interest in spending prolonged field work periods in Canada.
  • have strong skills in written English and experience with academic writing.

Remuneration and further information

The position is placed in government pay scale position code 1017 PhD. Fellow. PhD. Fellows are normally placed in pay grade 54 (NOK 501 200,-) on the Norwegian Government salary scale upon employment and follow ordinary meriting regulations.

Employment is conducted according to national guidelines for University and Technical College PhD scholars.

For further information, please contact Dr. Louise Chavarie, researcher at MINA, NMBU; E-mail: louise.chavarie@nmbu.no or Dr. Jean-Sébastien Moore; E-mail: jean-sebastien.moore@bio.ulaval.ca.

Information for PhD applicants and information to applicants

Rovdyrsinventering

Application

To apply online for this vacancy, please click on the ‘Apply for this job’ button above. This will route you to the University’s Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Application deadline: 21.10.2022

In the application, the candidate must confirm that information and documentation (in the form of attachments) submitted via the job application can also be used by NMBU in a possible admission process.

Applicants invited for an interview are expected to present original diplomas and certificates.

The following documents must be attached to the application:

  • Motivation letter (maximum 1 page)
  • Complete CV 
  • Certified copies of academic diplomas and certificates. (i.e. Diploma, transcript. Diploma supplement for both bachelor and master). Diplomas, transcripts and diploma supplements that are not in Norwegian or English must be uploaded in the original lan-guage. An English translation of these documents must also be at-tached.
  • Applicants from universities outside Norway are kindly requested to send a diploma supplement, or a similar document, which describes in detail the study program and grading system.
  • Documentation of proficiency in written and oral English
  • Names and contact details for two references
  • Additional relevant documentation of professional knowledge (for example, list of scientific works)

About The Faculty of Environmental Sciences and Natural Resource Management

The Faculty of Environmental Sciences and Natural Resource Management (MINA) works with nature and the environment, sustainable use of natural resources, biological and geological processes.

MINA’s employees undertake teaching, research and dissemination within the fields of geology, hydrology and limnology, soil science, environmental chemistry, forestry, ecology, natural resource management, renewable energy, and nature-based tourism.

Our vision is to be a key actor in knowledge production and dissemination, and our goal is to deliver research of high, international quality, and varied and excellent teaching. The faculty’s employees are significant participants within their respective fields of expertise, both nationally and internationally. The faculty is dominated by a vital research culture and high levels of scientific production.

The faculty has about 200 employees, 90 PhD students and 650 students.

Read more about MINA here.

Bilde av Tårnbygningen og parken

The Norwegian University of Life Sciences (NMBU)

NMBU has a particular responsibility for research and education that secures the basis for the life of future generations. Sustainability is rooted in everything we do and we deliver knowledge for life. NMBU has 1,900 employees of which about 300 phd scholarships and 6,700 students. The university is divided into seven faculties.

NMBU believes that a good working environment is characterised by diversity.

We encourage qualified candidates to apply regardless of gender, functional ability, cultural background or whether you have been outside the labour market for a period. If necessary, workplace adaptations will be made for persons with disabilities. More information about NMBU is available at www.nmbu.no.


 Read the job description at the university homepage

Apply for this job

Deadline

21st October 2022

Post expires on Friday October 21st, 2022

PhD student in systematic biology

Published: 2022-09-20

Uppsala University is a comprehensive research-intensive university with a strong international standing. Our ultimate goal is to conduct education and research of the highest quality and relevance to make a long-term difference in society. Our most important assets are all the individuals whose curiosity and dedication make Uppsala University one of Sweden’s most exciting workplaces. Uppsala University has over 54,000 students, more than 7,500 employees and a turnover of around SEK 8 billion.

The Department of Organismal Biology teaches and explores the evolution, development and function on the organismal level. For more information see www.iob.uu.se.

Read more about our benefits and what it is like to work at Uppsala University

The position is placed in the research group of Fabien Burki (https://www.burki-lab.net/) within the Systematic Biology program at the Department of Organismal Biology (Evolutionary Biology Center, Uppsala University). In the Burki lab, we study the broad diversity of eukaryotes, which is mainly microbial, to understand some of the main transitions in broad eukaryote evolution such as the origin of plastids. This position is within an ERC-funded project: Establishing a new framework of plastid evolution derived from the characterization of novel diversity of unicellular eukaryotes

Project description
The Burki lab was recently awarded an ERC Consolidator grant (PlastidOrigin) that aims to study one of the most transformative events in eukaryote evolution–the origin of the photosynthetic organelles (the primary plastids). The main aim of this PhD position is to characterize novel environmental diversity that diverged near the origin of Archaeplastida–the supergroup of eukaryotes where plastids were established more than 1.5 billion years ago. We aim to identify and phylogenetically resolve microbial lineages that have never been seen before in order to produce a comprehensive evolutionary framework for the origin of plastids that include this crucial environmental diversity. A suite of methods will be employed, including long-read metabarcoding, single-cell transcriptomics, metagenomics, phylogenomics, cultivation, microscopy.

Duties
The position involves lab work and bioinformatics. Lab work may include: sampling, cell isolation, imaging with advanced microscopy, cell-sorting, attempts for cultivation of interesting cells in enrichment cultures, and library preparation for metabarcoding and HTS sequencing. Bioinformatics includes analysis of diversity datasets, phylogenetics, analysis of genomic datasets, phylogenomic. Disseminate results in appropriate formats, including leading peer-reviewed publications and conferences. Training will be provided when necessary.

Requirements
Completed university education of 240 university points (högskolepoäng, hp) out of which 60 hp on advanced level corresponding to master degree in relevant field to the project. Expertise and knowledge in microbial sampling as well as handling and culturing protist cells are beneficial. Background in eukaryotic diversity will be seen as highly valuable. A suite of methodologies will be used as described in the project description and are desirable attributes of the candidate. In particular, proven expertise in bioinformatics (e.g. phylogeny, genomics) and use of a scripting language (Python, R) are essential. A global assessment of the expertise will be made based on the candidates. Great emphasis is placed on personal qualities such as high-motivation, planning and organizational skills, problem solving and good collaborations and communication skills with team-members and other researchers. The applicant should have documented experience and proficiency in oral and written presentation in English.

Additional qualifications
In filling this position, the university aims to recruit the person who, in the combined evaluation of competence, skills and documented qualifications, is judged most suitable to carry out and develop the work-in-hand and to contribute to a positive development of the department.

Position
The PhD-student position is a 4-year appointment, and the candidate will primarily devote the time to his/her own research studies. Other departmental work, such as teaching or administration are typically part of the position (maximum 20 %). Salary placement is in accordance with local guidelines at Uppsala University. The applicant must be eligible for PhD studies at Uppsala University.

Information about research education can be found at the web site of the Faculty of Science and Technology, http://www.teknat.uu.se/Doktorand/.

Rules governing PhD students are set out in the Higher Education Ordinance chapter 5, §§ 1-7 and in Uppsala University’s rules and guidelines.

About the employment
The employment is a temporary position according to the Higher Education Ordinance chapter 5 § 7. Scope of employment 100 %. Starting date 2023-01-01 or as agreed. Placement: Uppsala

For further information about the position, please contact: Dr. Fabien Burki; fabien.burki@ebc.uu.se. 

Please submit your application by 20th of October 2022, UFV-PA 2022/3349.

Are you considering moving to Sweden to work at Uppsala University? Find out more about what it´s like to work and live in Sweden.  

Please do not send offers of recruitment or advertising services.

Submit your application through Uppsala University’s recruitment system.

Deadline: 2022-10-20 at 23:59
Unit: Department of Organismal Biology

Read the job description at the university homepage or apply.

Post expires on Thursday October 20th, 2022

PhD fellowship in structural biology and pharmacology

PhD fellowship in structural biology and pharmacology

PhD Project in the Autzen Lab

Department of Biology

Faculty of SCIENCE

University of Copenhagen

The Autzen Lab is inviting applications for a three-year PhD fellowship in membrane protein biochemistry, pharmacology, and structural biology in the Section for Biomolecular Sciences, at the Department of Biology, University of Copenhagen, Denmark. The fellowship is part of the Project “A spoon full of sugar makes the medicine go down” funded by the Novo Nordisk Foundation.

The start date is February 1st, 2023, or as soon as possible thereafter.

We are looking for a candidate with a background in structural biology, biophysics, molecular biology, biochemistry, molecular biomedicine, cell biology or neuroscience.

Research area and project description

Our sensation of taste influences our dietary choices and alert us about harmful foods, but the underlying molecular mechanisms of taste are poorly understood. This project aims at advancing our understanding of the molecular mechanisms underlying taste perception by studying the structure, dynamics, and function of membrane-bound taste receptors. The PhD candidate will apply single particle cryo-electron microscopy (cryo-EM) in combination with biochemical, pharmacological, and cellular assays to characterize taste receptors. The outcome of the project will yield unprecedented molecular insight into taste perception and delineate the therapeutic and diagnostic potential of an entire family of proteins.

The Autzen Lab at University of Copenhagen

The PhD candidate will join the Autzen Lab, a young research group in the Section for Biomolecular Sciences (BMS), at the Department of Biology. Home to 11 labs specializing in cellular and protein biology, protein design or structural biology, BMS is an international and interdisciplinary workplace, offering a vibrant, creative, and stimulating research environment. Read more about BMS here: https://www1.bio.ku.dk/english/research/bms/

The Autzen Lab is focused on characterizing the activation and modulation of eukaryotic membrane proteins involved in selected, cellular pathways to elucidate their basic function and therapeutic potential. The lab is also developing tools for detergent-free membrane protein purification to conserve native protein-lipid interactions. The lab houses state-of-the-art equipment for large-scale mammalian protein production, and purification, biochemical and biophysical characterizations, and data processing and is a core-user of the state-of-the-art cryo-EM facilities at the Core Facility for Integrated Microscopy on campus.

The Autzen Lab is built on community, trust, openness, honesty, and solidarity and strives to embody the scientific method, objectivity, and reproducibility. We value open science, knowledge and data sharing and science communication to a wider audience, ultimately bridging the gap between society and research. Read more about the Autzen Lab and our core values on our website: www.autzenlab.com.

We offer you

  • An exciting and stimulating research project set in a creative, scientifically strong, and international academic environment.
  • An open and inclusive work and research environment with dedicated colleagues.
  • Room for personal and professional development.

Principal supervisor is Associate Professor Henriette E. Autzen, Department of Biology, henriette.autzen ( at ) bio.ku.dk.

The PhD program

The PhD program consists of three years of full time study, and require you to have completed a degree program, equivalent to a Danish master’s degree (180 ECTS/3 FTE BSc + 120 ECTS/2 FTE MSc) related to the subject area of the project, e.g. in biophysics, biology, molecular biology, biochemistry, molecular biomedicine, cell biology, neuroscience or similar. For information of eligibility of completed programmes, see General assessments for specific countries and Assessment database.

Terms of employment

  • Employment as PhD fellow is full time and for maximum 3 years.
  • The employment is conditioned upon the applicant’s successful enrolment as a PhD student at the PhD School of SCIENCE, University of Copenhagen, which requires submission and acceptance of an application for the specific project.
  • Terms of appointment and payment accord to the agreement between the Danish Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. The position is covered by the Protocol on Job Structure.

Job description

Your key tasks as a PhD student at the Faculty of SCIENCE are to:

  • Actively manage and carry out an independent research project under supervision.
  • Attend, and complete PhD courses or other equivalent education corresponding to approximately 30 ECTS points.
  • Actively participate in research environments including at an external research institution, preferably abroad.
  • Disseminate your research through scientific manuscripts aimed at high-impact journals and presentations at national or international meetings.
  • Teach undergraduate or graduate students in the Autzen lab and in courses offered by the Department of Biology, University of Copenhagen.
  • Conclude your PhD studies by writing and defending your PhD thesis.

Your qualifications

Key criteria for the assessment of applicants are:

  • Qualifications corresponding to a Danish MSc degree with good results.
  • Completed courses or research experience in protein structure and function, biochemistry, physical chemistry, pharmacology, and/or biophysics.
  • Demonstrated ability to quickly grasp and employ new methods and tools.
  • Proficiency in spoken and written English.

As criteria for the assessment of your qualifications, emphasis will also be laid on publications, and relevant work or research experiences.

We are looking for a candidate with the following qualifications:

  • Recombinant DNA techniques and cloning.
  • Protein expression and purification for structural and functional studies.
  • Mammalian cell culture techniques.
  • Cryo-EM sample preparation and/or protein crystallization, data collection and analysis, including the use of relevant software.
  • Carrying out pharmacological assays (ex vivo, in vivo, or in vitro) and analysis of associated data.
  • Working with Linux operating systems.
  • Basic programming (MatLab and/or Python).
  • Data management and reporting.
  • High level of motivation, responsibility, and ability to work in a structured manner.
  • An ability to work independently and as part of a team.
  • A curious mind-set with a strong interest in understanding the molecular mechanisms of proteins.

Application and Assessment Procedure

Your application must be written in English and submitted electronically by clicking the ‘APPLY NOW’ below. The application must include the following documents in PDF format:

  1. Motivated letter of application (max. one page).
  2. Curriculum vitae incl. your education, experience, language skills and other skills relevant for the position (max. two pages).
  3. Original diplomas for Bachelor of Science or Master of Science and transcript of records in the original language, including an authorized English translation if issued in another language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted.
  4. Publication list (if applicable).
  5. Reference letters (if available)

Application deadline

The deadline for applications is the 16th of October, 2022 23:59 GMT+2.

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process

After deadline, a number of applicants will be selected for academic assessment by an unbiased expert assessor. You are notified, whether you will be passed for assessment.

The assessor will assess the qualifications and experience of the shortlisted applicants with respect to the above-mentioned research area, techniques, skills and other requirements. The assessor will conclude whether each applicant is qualified and, if so, for which of the two models. The assessed applicants will have the opportunity to comment on their assessment. You can read about the recruitment process here.

Interviews are expected to be held in week 46 and 47.

Questions

For further information, applicants may contact the supervisor Associate Professor Henriette E. Autzen, email: henriette.autzen ( at ) bio.ku.dk.

General information about PhD study at the Faculty of SCIENCE is available at the PhD School’s website here.

Living in Copenhagen, Denmark

Despite cold and rainy days in plenty, Denmark is among the happiest according to the World Happiness Report and Copenhagen is regularly ranked among top 5 cities to live in, particularly for expats. Whether you are into ancient sculptures or contemporary art, opera or heavy metal Copenhagen is ready to teach, inspire and entertain. Furthermore, with an extensive public transportation system, beautiful, tranquil nature is only minutes away from the city center.

For more information on working and living in Denmark, visit University of Copenhagen’s website on International Staff Mobility and WorkinDenmark.

University of Copenhagen

The university offers an inspiring research and teaching environment to its 37,000 students, and its 10,000 employees. University of Copenhagen is an international work and study environment commemorating democracy, openness, and equal opportunities. The University is an inclusive workplace that wishes to attract the most talented students and staff regardless of personal background. The University is keen to create a tolerant culture where everyone is treated equally, and where diversity is a strength, not a challenge. Read more about the university’s action plan for equality and diversity here: https://about.ku.dk/profile-history/diversity/

Deadline: 2022-10-16 at 23:59
Unit: Faculty of Science

Read the job description at the university homepage or apply.

Post expires on Sunday October 16th, 2022

Postdoctoral Researcher in Circadian Biology and Metabolism

Do you want to contribute to better health for all?

Within our research group you will find a unique opportunity to work with cutting edge research in the intersection between circadian rhythms, metabolism and neuroendocrinology. We offer an engaging and international research environment where you may contribute to high quality research on an internationally competitive level.

Your mission

Our group is an integral part of the unit of endocrinology at the department of medicine in Huddinge and is led by Paul Petrus. We are looking for a highly motivated postdoctoral researcher interested in circadian biology and metabolism. You will work on a project combining bioinformatic analyses as well as functional characterization using murine in vivo systems. You will be involved in designing and conducting simulated shift-work/jet lag experiments in mice followed by metabolic phenotyping using metabolic cages and ex vivo analyses. The metabolic changes observed in mice with perturbed circadian rhythms will be compared to other circadian datasets to identify clinically relevant processes that will be manipulated in down-stream experiments. The position provides an exciting opportunity for the successful candidate to apply their expertise in metabolism and excel in the space between bioinformatics, bench work and animal work. The goal of our research is to design interventions targeting the circadian system with therapeutic relevance for metabolic diseases.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant’s main supervisor, director or equivalent.

Qualified to be employed as a postdoctor is one who has obtained a doctorate. The applicant is expected to have a documented research experience within the field of metabolism. Candidates with expertise in adipose tissue and liver biology will be prioritized. Prior work using mouse models is a requirement and experience with metabolic- and/or behavioural- phenotyping is a plus. We are looking for a postdoc with the following profile:

  • Bioinformatic experience working with RNA-seq and metabolomics data using R.
  • Experience in managing and handling mouse colonies.
  • Basic wet-lab experience (isolating RNA/DNA/protein, performing Western blots, qPCR etc.)
  • Strong background in the field of metabolism and experience working with liver and white adipose tissue.
  • Experience working with circadian rhythms is a plus.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.


Location:
 Stockholm, Flemingsberg


Choose to work at KI – Ten reasons why

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work A complete list of publications A summary of current work (no more than one page)

Welcome to apply at the latest 2022-10-06

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all

Deadline: 2022-10-06 at 23:59
Unit: Department of Medicine, Huddinge

Read the job description at the university homepage or apply.

Post expires on Thursday October 6th, 2022

PhD Scholarship within Chemistry and Biotechnology

About the position

The Faculty of Chemistry, Biotechnology and Food Science (KBM) at the Norwegian University of Life Sciences (NMBU) has a vacant three year PhD–position related to chemistry and biotechnology, with the possibility of extension for up to one year if teaching and other work duties are agreed upon. 

The current transition from an oil-based economy to a circular bioeconomy implies full utilization of processed biomass. Thus, the food industry is constantly working to improve processing of raw materials and side-streams, with the aim of full utilization and increasing profitability. The development of high-end products for food, nutraceutical or pharmaceutical purposes from food processing side-streams is an important part of this development. To achieve this, it is necessary to improve our understanding of how the raw material composition, processing parameters and choice of operations influence the products’ physiochemical properties. The overall aim of the PhD project is to develop novel processes and high-end product applications by the valorization of side-streams from the meat and seafood industry. Collagen and the respective product applications will constitute an important part of the project, and the development of analytical tools for understanding and optimizing biomass processing will be a central part of the work.

We are seeking a dedicated and enthusiastic candidate for a PhD within chemistry and biotechnology. The PhD project has a strong multidisciplinary profile containing elements from organic chemistry, analytical chemistry, spectroscopy, chemometrics, food science and others. Candidates that thrive and have experience working in a multidisciplinary environment are therefore strongly encouraged to apply. The position will be part of ongoing activities at both NMBU and Nofima with the purpose to develop novel technology to produce high-end products through valorization of protein-rich food processing side-streams. The work will be carried out at Ås, Norway, and the candidate will collaborate closely with a multidisciplinary team from NMBU, Nofima and relevant food industry partners.

The applicant is made aware that an application for a PhD position at NMBU is at the same time an application for admission to a PhD program at the institution. The documentation that is necessary to ensure that the admission requirements are met must be uploaded as an attachment.

Main tasks

  • Plan and perform process experiments using protein-rich side-streams from food industry.
  • Develop analytical tools for monitoring and controlling the processes.
  • Analyze obtained experimental data applying chemometrics.
  • Identify and leverage key physiochemical success factors.
  • Participate in meetings with research partners and industry.

The successful candidate is expected to enter a plan for the progress of the work towards a PhD degree during the first months of the appointment, with a view to completing a doctorate within the PhD scholarship period.

KBM laboratoriet

Competence

The successful applicant must meet the conditions defined for admission to a PhD programme at NMBU. The applicant must have an academically relevant education corresponding to a five-year master’s degree with a learning outcome corresponding to the descriptions in the Norwegian Qualification Framework, second cycle. The applicant must have a documented strong academic background from previous studies and be able to document proficiency in both written and oral English. Written and oral communication skills in a Scandinavian language will be emphasized. For more detailed information on the admission criteria please see the PhD Regulations and the relevant PhD programme description.

The applicant must document expertise and interest in the research subject.

Required Academic qualifications

  • MSc in Analytical Chemistry, Organic Chemistry, or related area.
  • Experience from relevant laboratory work and experimental design.
  • Very good written and oral communication skills in English.

The following experiences and skills will be emphasized:

  • Very good written and oral communication skills in a Scandinavian language.
  • Experience with protein chemistry and bioprocessing.
  • Hands-on experience with infrared (IR) and nuclear magnetic resonance (NMR) spectroscopy.
  • Experience with multivariate data analysis, statistics, optics, or food quality.
  • It is beneficial to have an interest and/or skills in programming (e.g., MATLAB, Python or R).

Remuneration and further information

The position is placed in government pay scale position code 1017 PhD. Fellow. PhD. Fellows are normally placed in pay grade 54 (NOK 501.200,-) on the Norwegian Government salary scale upon employment and follow ordinary meriting regulations.

Employment is conducted according to national guidelines for University and Technical College PhD scholars.

For further information, please contact Associate Professor Kenneth Aase Kristoffersen

E-mail: kenneth.aase.kristoffersen@nmbu.no; phone +47 67231669

Information for PhD applicants and general Information to applicants

Laboratoriearbeid

Application

To apply online for this vacancy, please click on the ‘Apply for this job’ button above. This will route you to the University’s Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Application deadline: 20.10.2022

In the application, the candidate must confirm that information and documentation (in the form of attachments) submitted via the job application can also be used by NMBU in a possible admission process.

Applicants invited for an interview are expected to present original diplomas and certificates.

The following documents must be attached to the application:

  • Motivation letter (maximum 1 page)
  • Please note that applications that lack a motivation letter clearly stating why the candidate is qualified and motivated for this project will be disregarded.
  • Complete CV 
  • Certified copies of academic diplomas and certificates. (i.e. Di-ploma, transcript. Diploma supplement for both bachelor and master). Diplomas, transcripts and diploma supplements that are not in Norwegian or English must be uploaded in the original language. An English translation of these documents must also be attached.
  • Applicants from universities outside Norway are kindly requested to send a diploma supplement, or a similar document, which describes in detail the study program and grading system.
  • Documentation of proficiency in written and oral English in accordance with NMBU PhD regulation section 5-2 (3)
  • Names and contact details for two references
  • Additional relevant documentation of professional knowledge (for example, list of scientific works). If it is difficult to judge the applicant’s contribution for publications with multiple authors, a short description of the applicant’s contribution must be included.

About The Faculty of Chemistry, Biotechnology and Food Science

The Faculty of Chemistry, Biotechnology and Food Science (KBM) employs about 160 people. Currently about 50 PhD students are enrolled into our PhD program. KBM represents a broad range of scientific fields encompassing basic natural sciences such as microbiology, chemistry, biochemistry as well as the application of these towards food chemistry, technology and safety, biotechnology, bioprocessing and environmental issues. The Faculty is responsible for education, research and information within our fields of expertise and also has state-of-the-art instrumentation to perform research within these fields. KBM collaborates in networks and research projects both nationally and internationally. 


Further information: https://www.nmbu.no/en/faculty/kbm 

Bioteknologibygningen NMBU

The Norwegian University of Life Sciences

NMBU has a particular responsibility for research and education that secures the basis for the life of future generations. Sustainability is rooted in everything we do and we deliver knowledge for life. NMBU has 1,900 employees of which about 300 phd scholarships and 6,700 students. The university is divided into seven faculties.

NMBU believes that a good working environment is characterised by diversity.

We encourage qualified candidates to apply regardless of gender, functional ability, cultural background or whether you have been outside the labour market for a period. If necessary, workplace adaptations will be made for persons with disabilities. More information about NMBU is available at www.nmbu.no.


 Read the job description at the university homepage

Apply for this job

Deadline

20th October 2022

Post expires on Thursday October 20th, 2022

Postdoc for developing habitat condition metrics using fine-scale remote sensing and deep learning

The Department of Ecoscience, Aarhus University, invites applications for a postdoc position to support development of methods and tools for remote-sensing-based habitat condition measurements using AI and deep learning.

 

Expected start date and duration of employment

This is a 2-year postdoc position planned to start on January 1, 2023 or as soon as possible thereafter.
 

Job description

We are seeking applicants to support development of exciting new methods to measure the condition of habitats and their natural processes (e.g., grazing, hydrology etc.). Specifically, the aim is to develop measures based on airborne and UAV lidar point clouds and possibly other fine-scale remote sensing data. In the end, the goal is to enable estimation of the condition of a given habitat and the degree to which the intrinsic processes prevailing there are natural. The work is conducted as part of a new EU Horizon Europe project – Modern Approaches to the Monitoring of Biodiversity (MAMBO). An important focus is to develop methods that are scalable to enable meaningful habitat 

monitoring over large extents that can be implemented in different EU countries.

The candidate will work together with leading remote sensing and ecological specialists from Denmark, United Kingdom, The Netherlands and France.

Your profile

We are looking for a candidate with excellent skills in deep learning and the extraction of ecological information from remotely sensed (preferably lidar) data. In particular, strong proficiency in programming in Python, R and GIS is a prerequisite. A strong motivation and ability to work in international and interdisciplinary teams of biologists and remote sensing specialists is important as is a track-record of turning technical solutions into publications in leading scientific journals of the field.

The applicant is expected to have a PhD or equivalent within applied deep learning, i.e., from one or more projects where deep learning has been applied in ecology, biology or nearby fields. Ability to work and communicate well as part of a team is essential. Good English skills are necessary to communicate within the research team as well as with stakeholders.

The ability to work structured, documenting code and keeping it tidy is important to make collaboration with colleagues efficient.
 

Who we are

The Department of Ecoscience is engaged in research programmes, teaching curricula and advisory work covering the major biological sub-disciplines. We conduct world-class research in the areas of aquatic biology and ecology, arctic environment and ecosystems, biodiversity and conservation biology. The Department currently employs approximately 275 academic and technical staff, as well as many PhD students.
 

The successful applicant will join the Danish team in the project, which leads this part of project and will be associated with Department of Ecoscience.
 

What we offer

The Department offers a vibrant and informal research environment with longstanding traditions for collaboration with elite international university partners and with the Danish Ministry of the Environment.

The working environment at the Department is based on teamwork and close working relations. English is widely spoken and we welcome applicants from abroad. The Department has a strong work-life balance policy and seeks a good gender and age balance. Read more about the services available when relocating to Aarhus University at www.au.dk/work.
 

Place of work and area of employment

The place of work is C.F. Møllers Allé 8, DK-8000, Aarhus C, and the area of employment is Aarhus University with related departments.

 

Contact information

For further information, please contact: Researcher Jesper Erenskjold Moeslund, +45 23227111, jesper.moeslund@ecos.au.dk

Deadline

Applications must be received no later than October 31, 2022

 

Application procedure

Shortlisting is used. This means that after the deadline for applications – and with the assistance from the assessment committee chairman, and the appointment committee if necessary, – the head of department selects the candidates to be evaluated. All applicants will be notified whether or not their applications have been sent to an expert assessment committee for evaluation. The selected applicants will be informed about the composition of the committee, and each applicant is given the opportunity to comment on the part of the assessment that concerns him/her self. Once the recruitment process is completed a final letter of rejection is sent to the deselected applicants.

Letter of reference

If you want a referee to upload a letter of reference on your behalf, please state the referee’s contact information when you submit your application. We strongly recommend that you make an agreement with the person in question before you enter the referee’s contact information, and that you ensure that the referee has enough time to write the letter of reference before the application deadline.
Unfortunately, it is not possible to ensure that letters of reference received after the application deadline will be taken into consideration.

Formalities and salary range

Technical Sciences refers to the Ministerial Order on the Appointment of Academic Staff at Danish Universities under the Danish Ministry of Science, Technology and Innovation.

The application must be in English and include a curriculum vitae, degree certificate, a complete list of publications, a statement of future research plans and information about research activities, teaching portfolio and verified information on previous teaching experience (if any). Guidelines for applicants can be found here.

Appointment shall be in accordance with the collective labour agreement between the Danish Ministry of Taxation and the Danish Confederation of Professional Associations. Further information on qualification requirements and job content may be found in the Memorandum on Job Structure for Academic Staff at Danish Universities.

Salary depends on seniority as agreed between the Danish Ministry of Taxation and the Confederation of Professional Associations.

Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.

Research activities will be evaluated in relation to actual research time. Thus, we encourage applicants to specify periods of leave without research activities, in order to be able to subtract these periods from the span of the scientific career during the evaluation of scientific productivity.

Aarhus University offers a broad variety of services for international researchers and accompanying families, including relocation service and career counselling to expat partners. Read more here. Please find more information about entering and working in Denmark here.

Aarhus University also offers a Junior Researcher Development Programme targeted at career development for postdocs at AU. You can read more about it here.

The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.

Deadline: 2022-10-31 at 23:59
Unit: Department of Ecoscience – Biodiversity and Conservation – Faculty: Technical Sciences
Email: mailto:jesper.moeslund@ecos.au.dk
Phone: +4523227111

Read the job description at the university homepage or apply.

Post expires on Monday October 31st, 2022

Postdoc positions in Molecular Biology at BRIC

Faculty of Health and Medical Sciences
University of Copenhagen

We are looking for a highly motivated and independent postdocs to provide experimental, scientific and operational support to the Cvejic Lab which is to commence on 15 December 2022 or soon thereafter.

Information on the department can be found at: BRIC – University of Copenhagen (ku.dk)

Our research
The aim of our group is to decipher how differentiation pathways of haematopoietic cells are influenced by different microenvironments. To achieve that we use state-of-the-art single-cell RNA-seq, single-cell ATAC-seq and spatial transcriptomics data generation combined with computational analysis to establish principles of blood lineage differentiation. We are working with human foetal haematopoietic cells to reveal the dynamics and cellular programmes active during human blood development as well as cancer patient samples to investigating the influence of tumour microenvironment in the context of pathological differentiation of immune cells. We are a team of highly collaborative researchers performing exciting interdisciplinary science using the cutting-edge experimental and computational technologies.

Your job
You will have a PhD with significant experience in molecular and cell biology. You will be able to demonstrate critical thinking, will be hard working, passionate about science, and keen to learn and improve skills in a supportive research environment. You will be part of a multidisciplinary team and will be tasked with proactively seeking and maintaining appropriate collaborations. You will be expected to contribute to and support the ongoing research projects in the group on an ad hoc basis when needed, working closely with biologists, clinicians and bioinformaticians within and outside the group to accomplish scientific objectives; disseminate your expertise to new lab members and support the lab management.

Profile
We are looking for a highly motivated and enthusiastic postdoc with the following competencies and experience.

Essential experience and skills:

  • You have a PhD in Life sciences or related
  • Extensive experience in molecular and cell biology techniques
  • Extensive experience in flow cytometry and cell culture
  • Experience and knowledge in CRISPR
  • An excellent research and publication track record
  • Highly organised
  • Ability to effectively prioritise, multi-task and work independently 
  • Good English skills, written and spoken

Desirable experience and skills:

  • Experience in working with patient-derived material
  • Experience in working with organoids
  • Haematology research
  • Multiomics approaches

Place of employment
The place of employment is at the BRIC, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories and core facilities Core Facilities – University of Copenhagen (ku.dk).

Terms of employment
The position is a full-time position (37 working hours weekly) limited to a period of 3 years. The starting date is 15 December 2022 or soon thereafter.  

Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Taxation and AC (Danish Confederation of Professional Associations) or other relevant organisation. Currently, the monthly salary starts at 35,500 DKK/approx. 4,770 EUR (October 2022 level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Foreign and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not been tax liable to Denmark the last 10 years.

The position is covered by the ‘Memorandum on Job Structure for Academic Staff at the Universities of December 11, 2019’.

Questions
For further information please contact Ana Cvejic on email: ana.cvejic@bric.ku.dk

Application
Your application in English should include:

  • Letter of application addressing the requirements (max. one page).
  • Curriculum Vitae
  • A certified/signed copy of certificate(s) of education (Master and PhD degree or equivalent)

Please submit your application by clicking on “Apply Now” below.

Application deadline: 19 October 2022, 23.59 CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background.

Deadline: 2022-10-19 at 23:59
Unit: Faculty of Health and Medical Sciences

Read the job description at the university homepage or apply.

Post expires on Wednesday October 19th, 2022

Doctoral (PhD) student position in next generation sequencing methods for the development of a novel biomaterial

The Department of Biosciences and Nutrition performs research and education in several areas of medical science including aging, Alzheimer, bioorganic chemistry, biomaterial, molecular endocrinology, cancer biology, functional genomics, systems biology, epigenetics, structural biochemistry, immunology, and nutrition. It offers an excellent international research and working environment, including around 250 scientists, students, administrative and technical personnel. The Department resides in Neo at Campus Flemingsberg, a biomedical research building, aimed at being a creative and open environment that enables meetings, synergies, and exploration of areas of mutual interest across disciplines.

Do you want to contribute to the development of a novel biomaterial?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

Our group has developed the first biomimetic method to spin artificial spider silk fibers and succeeded in establishing a production and purification method of recombinant silk proteins that results in unprecedented protein yields (Andersson et al. Nat Chem Biol. 2017; Schmuck et al. Mater Today. 2021). Furthermore, we have sequenced a whole spider genome of outstanding quality and have analyzed the transcriptome of the silk glands. Our research group consists of three PhD students, two technicians, four post docs and a bioinformatician, and is funded by the European Research Council, Swedish Research Council, FORMAS and Center for Innovative Medicine. The research group is located at Karolinska Institutet, campus Flemingsberg, and at SLU in Uppsala.

The doctoral student project and the duties of the doctoral student

We will employ an interdisciplinary approach to understand the processing and storage of silk proteins in the spiders’ glands. To do so we will use high-resolution microscopy techniques and use state-of-the-art sequencing methods to build a spatially resolved map of gene expression in the silk glands. Hopefully, these insights will help the research group in our quest to design proteins and spinning devices that can produce supreme artificial silk fibers.

The successful candidate is expected to have a profound interest in biology/bioinformatics/microscopy, enjoy practical lab work as well as bioinformatic analyses. You are expected to prepare samples and generate and analyze data, write papers and other scientific texts, and give seminars. You will pursue your projects independently with the support of the supervisors and fellow group members. The applicant will supervise master students in the lab. We work in collaboration with other groups and in an interdisciplinary way, which demands the applicant to be independent, creative, have a positive attitude and be collaborative. The applicant will work primarily at KI campus Flemingsberg but is also expected to travel to and work in the lab at SLU in Uppsala and research visits (for a few months) to other countries may be part of the job.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

  1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
  2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
  3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

The applicant must have theoretical knowledge of biology and bioinformatics (transcriptomics analysis by bioinformatics tools, as well as be able to write scripts in R. It is meritous if the applicant has previous experience of image analysis and microscopy. The applicant must be fluent in both written and spoken English. A positive attitude and strong drive to pursue research is desirable. Emphasis will be put on personal qualities in the selection process.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.


Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

https://ki.se/en/bionut/spider-silk-biology-for-biomedical-applications-anna-rising

Want to make a difference? Join us and contribute to better health for all

Deadline: 2022-10-13 at 23:59
Unit: Department of Biosciences and Nutrition

Read the job description at the university homepage or apply.

Post expires on Thursday October 13th, 2022

PhD position in genomics of major depression subtypes

Do you want to contribute to top quality medical research?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

We seek a PhD student who will conduct research at the KI-Psychiatric Genomics Institute (KI-PGI). The KI-PGI begins with fundamental genomic findings and then elucidates the implications for patients, clinicians, and neuroscientists. We are deeply collaborative, and we actively work with at least 10 major genetic, psychiatric, neuroscience, and functional genomic groups. We have established, long term collaborations within the KI, Sweden, Europe, the US, and Australia. We have multiple large new datasets, including expansion of the Swedish Schizophrenia Study (S3), Genomic Aggregation Project in Sweden (GAPS), and TRYGGVE2 (an effort to harmonize psychiatric genomics in Denmark, Norway, and Sweden).

The doctoral student project and the duties of the doctoral student

Applications are invited for a PhD research training position to investigate the epidemiology, genetics, and transcriptomics of subtypes of major depression.

These PhD project will involve the application of advanced statistical methods, molecular genetics and transcriptomics approach in large datasets with complex data types.

Under supervision, the PhD student will be responsible for literature review, data analysis, result interpretation, scientific article writing and data presentation.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

  1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
  2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
  3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

 

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

 

Skills and personal qualities

  1. The applicant should have a master’s degree in genetics, statistics, public health epidemiology, psychology, health informatic or related quantitative discipline, or comparable experience; and have a strong interest in psychiatric research.
  2. The applicant should have documented experience in psychiatric research especially depression.
  3. The applicant should have advanced skills in statistical analyses and basic understanding in genomics.
  4. Previous experience with GWAS (genome-wide association study) is considered a strong merit.
  5. Having experience with Nordic register data is a strong merit.
  6. Proficient programming skill in R or similar languages is considered a strong merit.
  7. Excellent oral and written communication skills in English are required, along with ample experience with scientific writing (e.g., first or co-author in published articles).
  8. The applicant should be able to work well in a team, as well as having the ability to work independently.
  9. The applicant should possess good organizational skills and know how to multitask.

 

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

 

https://ki.se/meb

https://ki.se/en/meb/ki-psychiatric-genomics-institute

 

Want to make a difference? Join us and contribute to better health for all

Deadline: 2022-10-14 at 23:59
Unit: Department of Medical Epidemiology and Biostatistics

Read the job description at the university homepage or apply.

Post expires on Friday October 14th, 2022

Doctoral student in Informatics with an orientation on Interaction design (licentiate)

Unspecified place of work

Reference number: 2021/840-2.2.1

Welcome to Linnaeus University! We meet the societal challenges of today and tomorrow in a spirit of openness, curiosity and creativity. By creating arenas for exchange of knowledge from different subjects, fields and cultures, we open up for new ideas and create new opportunities for long-term sustainable societal development. Linnaeus University – where people grow.

The Faculty of Technology strives to ensure that Linnaeus University’s vision permeates all activities, with a focus on the keywords: Attractive knowledge environment, Excellent research, Social drive, and Global values. The Faculty of Technology has broad operations spanning ten different departments through which Linnaeus University provides education and conducts research. The faculty has approximately 3 100 students at the undergraduate and advanced levels, 90 doctoral students and 300 teaching staff including administrators.

The Department of Informatics, where this position will be located, has about 35 employees, conducts research and education at two campus, in Kalmar and in Växjö. Informatics is the scientific subject that develops knowledge about people’s design and use of information and communication technology (ICT), also called digital technology. The focus for research and education is within the areas digital business development, information management, interaction design, eHealth and systems thinking.

Admitted to: Computer and Information Science
Terms of employment: 100 % employment as doctoral student till Licentiate Degree, with a possibility for extension to full PhD degree. The employment as a doctoral student is limited according to chapter 5, section 7 of the Higher Education Ordinance. The total employment period may not be longer than the equivalent full-time postgraduate studies of two years. If the employment is extended to Doctoral Degree, the total employment period may not be longer than the equivalent full-time postgraduate studies of four years.
Location: Växjö/Kalmar
Start: Autumn semester 2022 or according to agreement

Work description
An always current focus in informatics is how digitalisation affects people, organizations and society, and in this context, also the interaction between these factors, which contributes to increased participation and equality in society. For this position, methods and techniques related to design thinking are of special interest. Design thinking is a human-centered approach to innovation that draws from the designer’s toolkit to integrate the needs of people, the possibilities of technology, and the requirements for business success. In the light of the sustainability goals defined in Agenda 2030, the research will focus on how digital technology can be used to support health and wellbeing through the use of interactive technologies. Postgraduate education in informatics is part of the postgraduate education subject of computer and information sciences.

According to the Higher Education Ordinance, a person appointed to a doctoral studentship should primarily devote himself/herself to his/her own studies. An appointee may, however, work to a limited extent with education, research, artistic development, and administration. However, before a doctoral degree has been awarded, duties of this kind may not comprise more than 20% of a full-time position.

Requirements
General requirements

A person fulfils the general entry requirements if he/she has:

  • An advanced level degree
  • A completed undergraduate program of at least 240 credits, including 60 credits at the advanced level
  • Or the equivalent knowledge obtained in or outside of Sweden

Specific requirements

Specific prerequisites for admission to graduate studies in Computer and Information Science are required. A person fulfils the specific entry requirements if he/she has:

  • approved courses of a minimum of 90 credits in the subject Computer and Information Science or the equivalent, and
  • an individual study project of a minimum of 15 credits in the subject Computer and Information Sciences, or the equivalent.

Lastly, the applicant must be assessed as having the ability to pursue the studies.

Other requirements
It is essential that the candidate possess very good knowledge of the English language. Knowledge of the Swedish language is considered as an advantage.

The applicant must have capacity to conduct independent research within the described area. Interpersonal skills and ability to collaborate are of great importance since the work will be carried out in a research group and with external actors.

Previous professional experience and / or academic qualifications in a field relevant to the employment, as well as publications in scientific journals and conferences, are advantage. Selection of applicants is made with regard to the applicants’ ability to benefit from and to assimilate and utilize the content of the postgraduate program.

Assessment criteria
The selection to third cycle studies is based on the assessed ability to pursue the studies. The assessment focuses mainly on study results from first cycle and second cycle studies. The following is considered:

  1. Knowledge and skills relevant to the thesis work and the subject, see Work description above. These can be shown via attached documents
  2. Assessed ability to work independently and ability to formulate and approach scientific problems. The assessment may be based on the degree project and a discussion about this at a possible interview
  3. Level of written and oral communication
  4. Other merits relevant to the third cycle studies, e.g., professional experience

The following will also be considered: ability to work with others, ambition, independence, and personal aptitude, as well as the applicant’s assessed ability, based on their own experience and competence, to successfully complete the studies.

More information about assessment and selection criteria can be found in each subject’s General study plan for postgraduate education, please see https://lnu.se/en/research/PhD-studies/

Application process
Applicants are expected to submit their application in English, which should include:

  • A personal letter which states the reason for being interested in the position and in which ways the research project corresponds to your interests, experience, and educational background
  • A CV
  • Master’s degree transcripts/diploma, and copy, or link, to master degree project
  • Any other relevant documents (references, recommendation letter, transcript of records)
  • Proposal(s) for research project, maximum 1 A4 page per proposal

For further information, please contact

Head of department Arianit Kurti, 0470-70 83 75, arianit.kurti@lnu.se
Professor Anita Mirijamdotter, subject chair of Informatics, 0470-70 86 35, anita.mirijamdotter@lnu.se
HR partner Jesper Pettersson, jesper.pettersson@lnu.se 

We look forward to your application according to the instructions, no later than 17th of October.

Linnaeus University has the ambition to utilize the qualities that an even gender distribution and diversity brings to the organization.

Please apply by clicking on the Apply button at the bottom of the ad. Applicants are requested to the application resolving CV, cover letter , a copy of a relevant essay , grades and certificates and other relevant documents. The applicant also requested to submit with their application a proposed research plan within the current area of research. All documents must be attached to digital in the application. The application and other documents shall be marked with the reference number. All documents cited must be received by the University no later than 24.00 (Local time in Sweden) on the closing day.

Contact person

Read the job description at the university homepage

Apply

Post expires on Monday October 17th, 2022

Postdoctoral Researcher in Cognitive Neuroscience

Do you want to contribute to top quality medical research?

In our research group, you will find a unique opportunity to work together with top researchers in cognitive neuroscience to jointly try to understand how the brain encodes the attention of others. To achieve this goal, we conduct various research projects that lie in the relatively unexplored intersection between social cognition and attentional processing. We use several different methods, including functional magnetic brain imaging (fMRI), behavioral and psychophysical approaches (including advanced eye tracking), and intracranial electrophysiological (EEG) recordings in neurosurgical patients. We offer an engaging and international research environment where you get an opportunity to contribute to high-quality research at the highest international level.

Your mission

As a postdoctoral fellow in the group, you will lead a new project that aims to determine how autistic people process the attention of others. Our research group has characterized a novel mechanism by which the brain encodes others’ attention as an implied motion connecting agents to attended objects (the “Mind Beam” hypothesis). Although people show no awareness of this agent-to-object motion, it has a significant effect on motion-processing brain areas and behavioral measures, and on social cognitive decisions about the attention of others. Using fMRI and behavioral measurements, we want to investigate whether autistic people engage their visual motion systems when viewing other people gazing at objects, and compare their responses to a neurotypical cohort. The project is initially ongoing for 2 years, with possibility of extension. You will also be able to develop your own ideas within the areas of social cognition and attention. With the help of research assistants, you will be responsible for setting up experiments, analyzing data and writing scientific articles. We have access to two state-of-the-art 3-Tesla MRI scanners at the Karolinska Institutet and Stockholm University Brain Imaging Center (SUBIC), and collaborate with a group of neurosurgeons in Portland (Oregon, USA) for intracranial EEG experiments.

As a postdoctoral fellow, you are offered the opportunity to work in a successful and well-funded research group, and will be surrounded by a number of senior and junior researchers. Our research group collaborates with other groups at the department and a number of prominent research groups around the world, which provides an opportunity for international exchanges.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant’s main supervisor, director or equivalent.

We are looking for a talented, innovative, and enthusiastic researcher with a PhD in a relevant research field. The successful candidate has previous well-documented research experience of working with advanced fMRI analyses (ideally multivoxel pattern analyses) or other advanced experimental electrophysiology or related research experiences. Previous research experience on neurodevelopmental disorders is desirable, but not a requirement. A consistently excellent academic track record is required, including publications in high-quality international scientific journals. English is the main language of communication in the research group, therefore it is a requirement to have strong English skills in writing and speaking.

Potential candidates will be interviewed and personal skills and characteristics will be considered when filling the position.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.


Location:
Solna

Read more about the Department of Clinical Neuroscience
Read more about the research you will be part of

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)
  • Description of own ideas within the field that you want to pursue (optional, no more than one page)

Welcome to apply at the latest October 20th 2022

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all!

Deadline: 2022-10-20 at 23:59
Unit: Department of Clinical Neuroscience

Read the job description at the university homepage or apply.

Post expires on Thursday October 20th, 2022

PhD fellowship in Stress Neurobiology at the Department of Neuroscience in Copenhagen

Faculty of Health and Medical Sciences, University of Copenhagen

We are offering a fully-funded 3 years PhD fellowship in stress neurobiology starting 15 February 2023 or as soon as possible hereafter.

Our group and research
We are a systems neuroscience laboratory focusing on understanding the mechanisms by which neural circuits and behaviors are affected by stress, to better understand the etiology of mental disorders. Our expertise includes behavioral assays, neuronal tracing, in vivo calcium imaging of large populations of neurons (2 photon & light sheet microscope), opto/chemogenetics. We use transparent, transgenic larval zebrafish as a vertebrate model amenable to whole brain imaging at cellular resolution in vivo.

You will work under the supervision of Associate Professor Florence Kermen and receive active support in designing, discussing and publishing the results of your research project.

We are located in beautiful and well-connected Copenhagen. Frequent scientific and social events at the institute contribute to a collaborative and enjoyable work atmosphere.

Project description
You will use repeated stressor exposure or pharmacological manipulation of stress level, combined with quantitative behavioral assays and physiological measurements (e.g. ELISA) to characterize the immediate and long-term outcomes of early-life stress. Following this, you will use neurophysiological approaches (immunohistochemistry, in vivo calcium imaging) to investigate the adaptations taking place in neuromodulatory circuits.

Principal supervisor is is Associate Professor Florence Kermen, Department of Neuroscience, E-mail: florence.kermen@sund.ku.dk, Direct Phone: +45 22550187

Start:                15 February 2023

Duration:          3 years as a PhD student

Job description
Your key tasks as a PhD student at SUND are:

  • Carrying through an independent research project under supervision.
  • Completing PhD courses or other equivalent education corresponding to approximately 30 ECTS points.
  • Participating in active research environments including a stay at another research team.
  • Obtaining experience with teaching or other types of dissemination related to your PhD project
  • Teaching and disseminating your knowledge.
  • Writing a PhD thesis on the grounds of your project

Key criteria for the assessment of applicants
Applicants must have qualifications corresponding to a master’s degree related to the subject area of the project, e.g. human biology, neuroscience, molecular and cellular biology, animal physiology, or medicine. Please note that your master’s degree must be equivalent to a Danish master’s degree (two years).

Other important criteria are:

  • A high grade point average achieved
  • A certificate in Laboratory Animal science (FELASA)
  • Professional qualifications relevant to the PhD project
  • Previous publications
  • Relevant work experience
  • Other professional activities
  • A curious mind-set with a strong interest in scientific research and stress neurobiology and prior experience with practical lab work relevant to the project
  • Proficiency in written and spoken English

Place of employment
The place of employment is at the Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories, zebrafish research facility, and microscopy facility (https://cfim.ku.dk/).

Terms of employment
The average weekly working hours are 37 hours per week.

The position is a fixed-term position limited to a period of 3 years. The start date is 15 February 2023.

The employment is conditioned upon the applicant’s success­ful enrolment as a PhD student at the Graduate School at the Faculty of Health and Medical Sciences, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant.

The PhD study must be completed in accordance with The Ministerial Order on the PhD programme (2013) and the Faculty’s rules on achieving the degree.

Salary, pension and terms of employment are in accordance with the agree­ment between the Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary starts at approximately 27,800 DKK / Roughly 3,700 EUR (October 2021 level) plus pension.

Questions
For specific information about the PhD fellowship, please contact the principal supervisor.

General information about PhD studies at the Faculty of Health and Medical Sciences is available at the Graduate School’s website: https://healthsciences.ku.dk/phd/guidelines/

Application procedure
Your application must be submitted electronically by clicking ‘Apply now’ below. The application must include the following documents in PDF format:

1. Motivated letter of application (max. one page)

2. CV incl. education, research experience, language skills and the contact details of 2 academic references

3. Certified copy of original Master of Science diploma and transcript of records in the original language, including an authorized English translation if issued in other language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted. As a prerequisite for a PhD fellowship employment, your master’s degree must be equivalent to a Danish master’s degree. We encourage you to read more in the assessment database: https://ufm.dk/en/education/recognition-and-transparency/find-assessments/assessment-database. Please note that we might ask you to obtain an assessment of your education performed by the Ministry of Higher Education and Science

4. A copy of your Master’s thesis. If the thesis is ongoing, a draft or a 2-page summary of your work.

5. Publication list (if relevant), including a brief description of your contributions to joint works.

Application deadline: 18 October 2022, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.

The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement.

Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You find information about the recruitment process at: https://employment.ku.dk/faculty/recruitment-process/

The applicants will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background. 

Deadline: 2022-10-18 at 23:59
Unit: Faculty of Health and Medical Sciences

Read the job description at the university homepage or apply.

Post expires on Tuesday October 18th, 2022

PhD fellowship in “Identification of epigenetic and F-actin regulators improving the efficiency of ex vivo gene therapy” at the Biotech Research and Innovation Centre (BRIC), University of Copenhagen

The PhD is part of the EU funded “Gene Therapy of Rare Diseases” Doctoral Network (GetRadi) which is a MSCA Doctoral Network.

Within the European Union’s Horizon Europe research and innovation programme under the Marie Skłodowska-Curie Action (MSCA), University of Copenhagen is offering one PhD position for a Doctoral Candidate (DC), commencing on 1 March 2023. The position is for 36 months and is funded by Horizon Europe.

The successful applicant will join a multidisciplinary EU-funded Marie Skłodowska-Curie International PhD training network. This interdisciplinary doctoral position is based at the Department of BRIC (the Biotech Research and Innovation Centre), Brakebusch Group, at the University of Copenhagen (UCPH). The position will be supervised by Professor Cord Brakebusch.

For further information, applicants may contact the main supervisor Cord Brakebusch, e-mail: cord.brakebusch@bric.ku.dk, direct phone: +45 35325619.

The GetRadi Doctoral Network
Rare diseases are affecting more than 30 Mio people in the EU and are in most cases caused by genetic mutations. The only curative treatment for patients suffering from these diseases is gene therapy, but many technical problems still need to be solved before safe and affordable somatic gene therapy will be a clinical routine. Aim of the EU funded Doctoral Network “Gene Therapy of Rare Diseases” (GetRadi) is to train 10 PhD students to become exceptional experts in gene therapy of rare diseases. In their research projects, the students will aim to overcome major technical challenges that still prevent the widespread use of somatic gene therapy in the clinic. All projects are embedded in a tight and synergistic academic-industrial collaboration to develop marketable products for the application of gene therapy. This GetRadi training will allow young scientists to spearhead future research efforts in gene therapy of rare diseases.

More information can be found on the GetRadi’s homepage www.getradi.ku.dk

The project
Chromatin modifications and nuclear F-actin have been shown to affect genome editing efficiency. The underlying molecular mechanism, however, is unclear, and the effects might be highly dependent on the extent and timing of the chromatin alteration. Initiated by the recent finding of our group of a methylation inihibitor improving CRISPR genome editing efficiency by HDR, we will now investigate by a CRISPR ko screen the role of chromatin and nuclear F-actin modifying genes on the efficiency of the repair of a single nucleotide variant by genome editing. This will identify novel pathways to increase the efficiency of defined gene repair during gene therapy of rare diseases.

The group
Prof. Cord Brakebusch’s group at BRIC, University of Copenhagen, has extensive experience in the generation and analysis of genetically modified mice and was one of the first groups in Scandinavia using CRISPR genome editing for that purpose (https://www.bric.ku.dk/research-groups/Research/Brakebusch_Group/). Major research interest of the group in addition to genome editing technologies is the Rho GTPase signaling in vivo during development and disease and in the nucleus, where it links with epigenetic regulation and DNA repair.

The institution
BRIC is a Center of Excellence at the University of Copenhagen with a strong focus on molecular mechanisms underlying disease (www.bric.ku.dk). More than 20 ambitious groups are working at BRIC in a highly collaborative atmosphere, supported by state-of-the-art Core Facilities and administrative services.

Required qualifications

  • Master’s degree in life sciences. Please not that your master’s degree must be equivalent to a Danish master’s degree (two years 120 ECTS/2 FTE MSc + 180 ECTS/3 BSc)
  • Enthusiasm for research
  • Good English skills, written and spoken
  • Collaborative, interactive mindset
  • Experience in molecular biology or animal research is of advantage

In addition aplication will be required to meet the MSCA Doctoral Network eligibility criteria, notably:

  • You must not have resided or carried out your main activity (work, studies, etc.) in Denmark for more than 12 months in the 36 months immediately before the start of your employment at UCPH. Compulsory national service, short stays such as holidays, and time spent as part of a procedure for obtaining refugee status under the Geneva Convention are not taken into account.
  • You must not be in possession of a doctoral degree when starting your employment at UCPH.

Applicants will only be considered for the position if they fulfill both of the above eligibility criteria.

Terms of employment
The position as PhD fellow is full time (37 working hours weekly) and lasts 3 years. It is funded by Horizon Europe and will start 1 March 2023.

The employment is conditioned upon the applicant’s successful enrolment as a PhD student at the Graduate School at the Faculty of Health and Medical Sciences, University of Copenhagen. This requires submission and acceptance of an application for the specific project to the Graduate School of Health and Medical Sciences.

The PhD study must be completed in accordance with The Ministerial Order on the PhD programme (2013) and the Faculty’s rules on achieving the degree.

Salary, pension and terms of employment are in accordance with the requirements from the European Commission related to the MSCA programme and the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary begins around DKK 28,300 roughly 3,800 EUR (taxable) plus pension (April 2022 level). In addition, a mobility allowance (gross amount 600 EUR per month from the EU to UCPH) and (if eligible) also a family allowance (gross amount 660 EUR per month from the EU to UCPH).

For more information on working and living in Denmark visit http://ism.ku.dk (International staff mobility) and https://www.workindenmark.dk

Application procedure
Your application, written in English, may be submitted electronically by clicking “Apply now” below and should include the following documents in PDF format:

  • Motivated letter of application (max. one page)
  • CV incl. education, experience, language skills and other skills relevant for the position
  • Certified copy of original Master of Science diploma and transcript of records in the original language, including an authorized English translation if issued in other language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted.
  • As a prerequisite for a PhD fellowship employment, your master’s degree must be equivalent to a Danish master’s degree. We encourage you to read more in the assessment database: https://ufm.dk/en/education/recognition-and-transparency/find-assessments/assessment-database. Please note that we might ask you to obtain an assessment of your education performed by the Ministry of Higher Education and Science.
  • Applicants with a Master´s degree from abroad should also enclose a short description of the grading scale used
  • Publication list (if relevant)
  • Other information to consider: References and recommendations (to consider)

The deadline for applications is 20 October 2022, 23.59pm CET

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.

The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement.

Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to him/herself.

Candidates will be assessed and short listed for interviews, which are supposed to take place mid-November. All candidates will be informed of the outcome of their application.

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/

The University of Copenhagen wishes to reflect the diversity of society and encourages all qualified candidates to apply regardless of personal background.

Deadline: 2022-10-20 at 23:59
Unit: Faculty of Health and Medical Sciences

Read the job description at the university homepage or apply.

Post expires on Thursday October 20th, 2022

PhD fellowship in “Easy monitoring of ex vivo and in vivo gene editing efficiency by a novel fluorescent reporter mouse for HDR and NHEJ mediated DNA repair” at the Biotech Research and Innovation Centre (BRIC), University of Copenhagen

The PhD is part of the EU funded “Gene Therapy of Rare Diseases” Doctoral Network (GetRadi) which is a MSCA Doctoral Network.

Within the European Union’s Horizon Europe research and innovation programme under the Marie Skłodowska-Curie Action (MSCA), University of Copenhagen is offering one PhD position for a Doctoral Candidate (DC), commencing on 1 March 2023. The position is for 36 months and is funded by Horizon Europe.

The successful applicant will join a multidisciplinary EU-funded Marie Skłodowska-Curie International PhD training network. This interdisciplinary doctoral position is based at the Department of BRIC (the Biotech Research and Innovation Centre), Brakebusch Group, at the University of Copenhagen (UCPH). The position will be supervised by Professor Cord Brakebusch.

For further information, applicants may contact the main supervisor Cord Brakebusch, e-mail: cord.brakebusch@bric.ku.dk, direct phone: +45 35325619.

The GetRadi Doctoral Network
Rare diseases are affecting more than 30 million people in the EU and are in most cases caused by genetic mutations. The only curative treatment for patients suffering from these diseases is gene therapy, but many technical problems still need to be solved before safe and affordable somatic gene therapy will be a clinical routine. Aim of the EU funded Doctoral Network “Gene Therapy of Rare Diseases” (GetRadi) is to train 10 PhD students to become exceptional experts in gene therapy of rare diseases. In their research projects, the students will aim to overcome major technical challenges that still prevent the widespread use of somatic gene therapy in the clinic. All projects are embedded in a tight and synergistic academic-industrial collaboration to develop marketable products for the application of gene therapy. This GetRadi training will allow young scientists to spearhead future research efforts in gene therapy of rare diseases.

More information can be found on the GetRadi’s home page www.getradi.ku.dk

The project
For the clinical application of genome editing, it is crucial that the genome editing tools reach the target cells both efficiently and selectively. Viruses, lipid nanoparticles, and viral particles are currently investigated and optimized to execute this task, but easy-to-use in vivo models to monitor efficiency and selectiveness of these methods are lacking. Aim of this project is therefore to establish a fluorescent reporter mouse that allows the easy comparison of efficiency and selectiveness of different in vivo and ex vivo genome editing technologies in any tissue at single-cell resolution.

The group
Prof. Cord Brakebusch’s group at BRIC, University of Copenhagen, has extensive experience in the generation and analysis of genetically modified mice and was one of the first groups in Scandinavia using CRISPR genome editing for that purpose (https://www.bric.ku.dk/research-groups/Research/Brakebusch_Group/). Major research interest of the group in addition to genome editing technologies is the Rho GTPase signaling in vivo during development and disease and in the nucleus, where it links with epigenetic regulation and DNA repair.

The institution
BRIC is a Center of Excellence at the University of Copenhagen with a strong focus on molecular mechanisms underlying disease (www.bric.ku.dk). More than 20 ambitious groups are working at BRIC in a highly collaborative atmosphere, supported by state-of-the-art Core Facilities and administrative services.

Required qualifications

  • Master’s degree in life sciences. Please note that your master’s degree must be equivalent to a Danish master’s degree (two year 120 ECTS/2 FTE MSc +180 ECTS/3 FTE BSc.)
  • Enthusiasm for research
  • Good English skills, written and spoken
  • Collaborative, interactive mindset
  • Experience in molecular biology or animal research is of advantage

In addition, applicants will also be required to meet the MSCA Doctoral Network eligibility criteria, notably:

  • You must not have resided or carried out your main activity (work, studies, etc.) in Denmark for more than 12 months in the 36 months immediately before the start of your employment at UCPH. Compulsory national service, short stays such as holidays, and time spent as part of a procedure for obtaining refugee status under the Geneva Convention are not taken into account.
  • You must not be in possession of a doctoral degree when starting your employment at UCPH.

Applicants will only be considered for the position if they fulfill both of the above eligibility criteria.

Terms of employment
The position as PhD fellow is full time (37 working hours weekly) and lasts 3 years. It is funded by Horizon Europe and will start 1 March 2023.

The employment is conditioned upon the applicant’s successful enrolment as a PhD student at the Graduate School at the Faculty of Health and Medical Sciences, University of Copenhagen. This requires submission and acceptance of an application for the specific project to the Graduate School of Health and Medical Sciences.

The PhD study must be completed in accordance with The Ministerial Order on the PhD programme (2013) and the Faculty’s rules on achieving the degree.

Salary, pension and terms of employment are in accordance with the requirements from the European Commission related to the MSCA programme and the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary begins around DKK 28,300 roughly 3,800 EUR (taxable) plus pension (April 2022 level). In addition, a mobility allowance (gross amount 600 EUR per month from the EU to UCPH) and (if eligible) also a family allowance (gross amount 660 EUR per month from the EU to UCPH).

For more information on working and living in Denmark visit http://ism.ku.dk (International staff mobility) and https://www.workindenmark.dk

Application procedure
Your application, written in English, may be submitted electronically by clicking “Apply now” below and should include the following documents in PDF format:

  • Motivated letter of application (max. one page)
  • CV incl. education, experience, language skills and other skills relevant for the position
  • Certified copy of original Master of Science diploma and transcript of records in the original language, including an authorized English translation if issued in other language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted.
  • As a prerequisite for a PhD fellowship employment, your master’s degree must be equivalent to a Danish master’s degree. We encourage you to read more in the assessment database: https://ufm.dk/en/education/recognition-and-transparency/find-assessments/assessment-database. Please note that we might ask you to obtain an assessment of your education performed by the Ministry of Higher Education and Science.
  • Applicants with a Master´s degree from abroad should also enclose a short description of the grading scale used
  • Publication list (if relevant)
  • Other information to consider: References and recommendations (to consider)

The deadline for applications is 20 October 2022, 23.59pm CET

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.

The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement.

Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to him/herself.

Candidates will be assessed and short listed for interviews, which are supposed to take place mid-November. All candidates will be informed of the outcome of their application.

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/

The University of Copenhagen wishes to reflect the diversity of society and encourages all qualified candidates to apply regardless of personal background.

Deadline: 2022-10-20 at 23:59
Unit: Faculty of Health and Medical Sciences

Read the job description at the university homepage or apply.

Post expires on Thursday October 20th, 2022

PhD student in systematic biology

Published: 2022-09-16

Uppsala University is a comprehensive research-intensive university with a strong international standing. Our ultimate goal is to conduct education and research of the highest quality and relevance to make a long-term difference in society. Our most important assets are all the individuals whose curiosity and dedication make Uppsala University one of Sweden’s most exciting workplaces. Uppsala University has over 54,000 students, more than 7,500 employees and a turnover of around SEK 8 billion.

The Department of Organismal Biology teaches and explores the evolution, development and function on the organismal level. For more information see www.iob.uu.se.

The position is placed in the research group of Fabien Burki (https://www.burki-lab.net/) within the Systematic Biology program at the Department of Organismal Biology (Evolutionary Biology Center, Uppsala University). In the Burki lab, we study the broad diversity of eukaryotes, which is mainly microbial, to understand some of the main transitions in broad eukaryote evolution such as the origin of plastids.

Read more about our benefits and what it is like to work at Uppsala University

Project description
The Burki lab was recently awarded an ERC Consolidator grant (PlastidOrigin) that aims to study one of the most transformative events in eukaryote evolution–the origin of the photosynthetic organelles (the primary plastids). The main aims of this PhD position are to study the roles of genetic transfers in the integration of an endosymbiont into an organelle. For this we will study the lineage Paulinella–a lineage of amoebae (unicellular eukaryotes) that established primary plastids relatively recently. While most of the research on Paulinella has been done on the photosynthetic species, i.e. the species that diverged after the establishment of plastids, we will instead look at the heterotrophic species that diverged close but before plastid establishment to test the hypothesis that gene transfers facilitating the endosymbiotic integration occurred before the establishment of the plastids from varying food sources. A suite of methods will be employed, including long-read metabarcoding, transcriptomics, phylogenomics, cultivation, microscopy.

Duties
The position involves lab work and bioinformatics. Lab work includes: field trips, sampling, cell isolation, imaging with advanced microscopy, attempts for cultivation of interesting cells in enrichment cultures, and library preparation for metabarcoding and HTS sequencing. Bioinformatics includes analysis of diversity datasets, phylogenetics, analysis of transcriptomic datasets, gene-tree species tree reconciliation. Disseminate results in appropriate formats, including leading peer-reviewed publications and conferences. Training will be provided when necessary.

Requirements
Completed university education of 240 university points (högskolepoäng, hp) out of which 60 hp on advanced level corresponding to master degree in relevant field to the project. The selected candidate must possess expertise and knowledge in microbial sampling as well as identifying and handling protist cells. Experience in culturing of microbial eukaryotes is required. Background in eukaryotic diversity will be seen as highly valuable. A suite of methodologies will be used as described in the project description and are desirable attributes of the candidate. In particular, proven expertise in bioinformatics (e.g. phylogeny, genomics) and use of a scripting language (Python, R) are essential. Great emphasis is placed on personal qualities such as high-motivation, planning and organizational skills, problem solving and good collaborations and communication skills with team-members and other researchers. The applicant must have documented experience and proficiency in oral and written presentation in English.

Additional qualifications
In filling this position, the university aims to recruit the person who, in the combined evaluation of competence, skills and documented qualifications, is judged most suitable to carry out and develop the work-in-hand and to contribute to a positive development of the department.

Position
The PhD-student position is a 4-year appointment, and the candidate will primarily devote the time to his/her own research studies. Other departmental work, such as teaching or administration are typically part of the position (maximum 20 %). Salary placement is in accordance with local guidelines at Uppsala University. The applicant must be eligible for PhD studies at Uppsala University.

Information about research education can be found at the web site of the Faculty of Science and Technology, http://www.teknat.uu.se/Doktorand/.

Rules governing PhD students are set out in the Higher Education Ordinance chapter 5, §§ 1-7 and in Uppsala University’s rules and guidelines.

About the employment
The employment is a temporary position according to the Higher Education Ordinance chapter 5 § 7. Scope of employment 100 %. Starting date 2023-01-01 or as agreed. Placement: Uppsala

For further information about the position, please contact: Dr. Fabien Burki; fabien.burki@ebc.uu.se. 

Please submit your application by 17th of October 2022, UFV-PA 2022/3359.

Are you considering moving to Sweden to work at Uppsala University? Find out more about what it´s like to work and live in Sweden.  

Please do not send offers of recruitment or advertising services.

Submit your application through Uppsala University’s recruitment system.

Deadline: 2022-10-17 at 23:59
Unit: Department of Organismal Biology

Read the job description at the university homepage or apply.

Post expires on Monday October 17th, 2022