Kategoriarkiv: Health/Life sciences

Postdoctoral Position in Stem Cell Biology and Single-cell Genomics

A postdoctoral position is available at the Natarajan Lab to study transcriptional regulation and cell-fate decisions in embryonic stem cells. Our interdisciplinary and international team is part of Danish-Institute of Advanced Study (D-IAS) and based at the Functional Genomics and Metabolism Unit, Department of Biochemistry and Molecular Biology, University of Southern Denmark (SDU). 

Role:
We are looking for a highly motivated and ambitious candidate to investigate transcriptional regulation, cell cycle and metabolic control in embryonic stem cells, using single-cell genomics and CRISPR approaches. The project would involve deriving transgenic stem cell lines, profiling using state-of-art approaches (bulk, single-cell transcriptomics, chromatin accessibility and multi-omics) and functional characterisation. The goal is to obtain mechanistic insights into dynamic stem cell regulation and cell-state transitions.

The selected applicant will be strongly supported by our skilled colleagues, our core infrastructure (single-cell genomics, sequencing etc.), Bio-imaging (DaMBIC) and computational facilities (eScience Centre, SDUCloud and National HPC Centre).

Profile:
We are looking for candidates with these competences and experience: 

Essential: 
• PhD in relevant areas (Natural sciences, molecular biology, developmental biology or systems biology)
• Prior training and expertise in stem cell/developmental biology and standard molecular biology techniques
• Prior experience in next-generation sequencing (NGS) approaches (RNA-seq, ChIP-seq or ATAC-seq etc.)
• First author manuscript in relevant journal in the field
• Proficiency in English (reading/writing/speaking).

Desirable: 
• Expertise with CRISPR approaches, flow cytometry and microscopy
• Prior experience in analysis of large-scale NGS data
• Interested in interdisciplinary and collaborative work.

Offer:
• A three-year postdoc position (extendable) with a competitive salary and social benefits (e.g. health coverage, parental leave, social security etc.)
• Access to state-of-the art technologies, facilities and infrastructure alongside international network
• Dedicated assistance and support with various practical, social, legal aspects (housing, visa, administration, tax etc.), especially for international candidates through our international staff office (ISO). 

Start date:  15 April 2020, but starting date is negotiable. Application deadline: 31 March 2020.

Informal queries and letters of interest are welcome. Please write to Kedar Natarajan, knn@bmb.sdu.dk.

Application, salary etc.
The successful applicant will be employed in accordance with the agreement between the Ministry of Finance and AC (the Danish Confederation of Professional Associations). Please check links for more information on salary and taxation.

The application must be in English and include the following:
• Motivation letter (max. one page)
• A curriculum vitae including research experience, information on previous employment and relevant skills
• A full list of publications stating the scientific publications on which the applicant wishes to rely
• Two letters of recommendation from supervisors or previous employers. Referees are welcome to send letters directly to anc@sdu.dk, mentioning candidate’s name and the position in question in the subject line. These must also reach us before deadline to be considered.

Shortlisting may be used in the assessment process.

Incomplete applications and applications received after the deadline will neither be considered nor evaluated.

To qualify you must have passed a PhD or equivalent. Applications will be assessed by an expert assessor/committee. Applicants will be informed of their assessment by the university.

The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

Applications must be submitted electronically using the link “Apply online”. Attached files must be in Adobe PDF or Word format. Each box can only contain a single file of max. 10 Mb. We strongly recommend that you read How to apply before you apply.

Further information for international applicants about entering and working in Denmark.

Deadline: 31 March 2020
Unit: Faculty of Science
Campus: Odense
Read the job description and apply online

Post expires on Tuesday March 31st, 2020

PhD fellowship in Plant Nutrition and Biotechnology

Department of Plant and Environmental Sciences, Faculty of Science at University of Copenhagen is offering a PhD scholarship in Plant Nutrition and Biotechnology commencing 01.06.2020 or as soon as possible thereafter.

Description of the scientific environment
The PhD research will be carried out within a project from the Independent Research Fund Denmark that investigates the molecular basis of zinc nutrition and homeostasis in plants, and strategies for developing zinc biofortification in crops. The student will be part of the Plant and Soil Science Section at the Department, under the supervision of Ass. Prof. Ana Assuncao.

Project description
Zinc is an essential micronutrient for plants and animals because of its structural and catalytic roles in many proteins. However zinc deficiency in soils and in human diet is a global problem, affecting mainly populations living on plant-based diets that rely on crops from zinc deficient soils. Plants maintain adequate zinc levels through tightly regulated zinc homeostasis mechanisms that include zinc uptake, transport and distribution. In our research group we study the molecular basis of this zinc homeostasis regulatory network and the zinc deficiency response, both in the model plant Arabidopsis and in the important crop rice. The aim of the PhD project will be to further analyse these regulatory networks, with a focus on F-bZIP transcription factors and the zinc sensing molecular mechanism. The tasks will involve a combination of approaches including molecular biology, genetics, mass-spectrometry, element analysis and bioimaging.

Principal supervisor is Associate Professor Ana G. L. Assuncao, Department of Plant and Environmental Sciences, Email: agla@plen.ku.dk .

Job description
The position is available for a 3-year period and your key tasks as a PhD student at SCIENCE are:

  • To manage and carry through your research project
  • Attend PhD courses
  • Write scientific articles and your PhD thesis
  • Teach and disseminate your research
  • To stay at an external research institution for a few months, preferably abroad
  • Work for the department

Formal requirements
Applicants should hold an MSc degree in Plant Biology, Agriculture, Biotechnology or other related fields, with good results. The applicant is also expected to have excellent English skills. As criteria for the assessment of your qualifications emphasis will also be laid on previous publications (if any) and relevant work experience.

Terms of employment
The position is covered by the Memorandum on Job Structure for Academic Staff.
Terms of appointment and payment accord to the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State.
The starting salary is currently at a minimum DKK 328.355 (approx. €43,750) including annual supplement (+ pension at a minimum DKK 53,360). Negotiation for salary supplement is possible.

Application Procedure
The application, in English, must be submitted electronically by clicking APPLY NOW below.

Please include

  • Cover Letter, stating which PhD project you are applying for and detailing your motivation and background for applying for the specific PhD project.
  • CV
  • Diploma and transcripts of records (BSc and MSc)
  • Other information for consideration, e.g. list of publications (if any)
  • Full contact details (Name, address, telephone and email) of 2 professional referees

The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

The deadline for applications is 29 March 2020, 23:59 GMT +1. 

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Interview Committee. Afterwards an assessment committee will be appointed to evaluate the selected applications. The applicants will be notified of the composition of the committee and the final selection of a successful candidate will be made by the Head of Department, based on the recommendations of the assessment committee and the interview committee.

The main criterion for selection will be the research potential of the applicant and the above mentioned skills. The successful candidate will then be requested to formally apply for enrolment as a PhD student at the PhD school of Science. You can read more about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/ .

Questions
For specific information about the PhD scholarship, please contact the principal supervisor [Associate Professor Ana Goncalves Leite de Assuncao, Department of Plant and Environmental Sciences, agla@plen.ku.dkDirect Phone: +45-35331274].
General information about PhD programmes at SCIENCE is available at http://www.science.ku.dk/phd.

 

APPLY NOW

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Deadline: 29 March 2020
Unit: Faculty of Science
Campus: Department of Plant and Environmental Sciences

Phone:
Read the job description and apply online

Post expires on Sunday March 29th, 2020

Postdoctoral Positions in Algorithmic Cheminformatics

Several two-year postdoc positions starting 1 July 2020 are available at the University of Southern Denmark (SDU) for research on an exciting project in algorithmic cheminformatics supported by the Novo Nordisk Foundation: “From Category Theory to Enzyme Design – Unleashing the Potential of Computational Systems Chemistry”. We are seeking highly motivated individuals with a PhD in computer science, computational chemistry/biochemistry, or related areas. The ideal candidate has familiarity with several of the following areas: concurrency theory, graph transformation, algorithmics, algorithm engineering, systems chemistry, systems biology, metabolic engineering, or enzyme design. Solid competences in programming and ease with formal thinking are prerequisites.

The project is based on the novel application of formalisms, algorithms, and computational methods from computer science to questions in systems biology and systems chemistry. We aim to expand these methods and their formal foundations, create efficient algorithms and implementations of them, and use these implementations for research in understanding the catalytic chemistry of enzymes.

The Algorithmic Cheminformatics group at the Department of Mathematics and Computer Science at SDU offers a dynamic research environment, comprising two full professors, an assistant professor, and several students. The project includes partnerships with Harvard Medical School (Department of Systems Biology) and the University of Vienna (Institute for Theoretical Chemistry), who will host the postdoctoral researcher for extended visits. 

The research group is located at the main campus of SDU, which is located in Odense, the third largest town in Denmark, 1:20 hours by train west of Copenhagen. Denmark is known for its high standards of living, free health care, and competitive salaries. Applicants from outside Denmark are eligible for substantial tax reductions. 

Application deadline: 20 March 2020.

For further information contact Professor Daniel Merkle (e-mail: daniel@imada.sdu.dk, phone: +45 6550 2322).

Application, salary etc.
The successful applicant will be employed in accordance with the agreement between the Ministry of Finance and AC (the Danish Confederation of Professional Associations). Please check links for more information on salary and taxation.

The application must include the following:
• A curriculum vitae including information on previous employment.
• A full list of publications stating the scientific publications on which the applicant wishes to rely.

Shortlisting may be used in the assessment process.

Incomplete applications and applications received after the deadline will neither be considered nor evaluated.

To qualify you must have passed a PhD or equivalent. Applications will be assessed by an expert assessor/committee. Applicants will be informed of their assessment by the university.

The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

Applications must be submitted electronically using the link “Apply online”. Attached files must be in Adobe PDF or Word format. Each box can only contain a single file of max. 10 Mb. We strongly recommend that you read How to apply before you apply.

Further information for international applicants about entering and working in Denmark.

Deadline: 20 March 2020
Unit: Faculty of Science
Campus: Odense
Read the job description and apply online

Post expires on Friday March 20th, 2020

PhD scholarship in Evolution of Secondary Metabolite production in bacteria at the Center for Microbial Secondary Metabolites, CeMiSt

We offer a PhD fellowship at Department of Biotechnology and Biomedicine (DTU Bioengineering) at the Technical University of Denmark. The PhD project is part of the Center for Microbial Secondary Metabolites, CeMiSt and will be carried out in the Bacterial Interactions and Evolution Group headed by Professor Ákos. T. Kovács in the Section for Microbial and Chemical Ecology.

 

CeMiSt is a Center of Excellence funded by the Danish National Research Foundation. The Center started in 2018 and will run for six years with an option for a four-year extension. The Center is based at the Technical University of Denmark and hosted by Department of Biotechnology and Biomedicine (DTU Bioengineering). Three DTU departments and 10 senior faculty participate in the Center and >10 PhD students and postdocs are hired. The purpose of CeMiSt is to unravel the biological role of microbial secondary metabolites in natural microbiological communities. The Center is led by Professor Lone Gram.

 

We are seeking a candidate to study the evolution of bacterial secondary metabolite production using experimental evolution and genome analysis. You will be involved in a fun PhD project on microbial natural products, with strong international connections, a productive scientific environment, and a good work-life balance.

 

Responsibilities and tasks

Your PhD project will contribute to our understanding of gene cluster evolution related to microbial secondary metabolite (SM) production. You will perform experimental evolution using Bacillus subtilis under various conditions and analyse mutation frequency in biosynthetic gene clusters compared to the rest of the genome. In addition, you will determine the genome phylogeny in the Bacillus genus to determine the turnover and evolutionary rates of SM gene clusters.

 

Your experience within the areas of microbiology and/or computational biology will be an advantage, including:

  • experimental evolution
  • molecular microbiology
  • genome sequence analysis
  • evolutionary theory
  • microbial secondary metabolites
Previous experience in R/Python is advantageous.
 
Expected starting date: June/July 2020.
 

Qualifications
Candidates should have a master’s degree in molecular biology, biology, engineering or a similar degree with an academic level equivalent to the master’s degree in engineering.

 

Approval and Enrolment

The scholarship for the PhD degree is subject to academic approval, and the candidates will be enrolled in one of the general degree programmes of DTU. For information about the general requirements for enrolment and the general planning of the scholarship studies, please see the DTU PhD Guide.

 
Assessment

The assessment of the applicants will be made by 1st May 2020 by Professor Ákos T. Kovács and Professor Tilmann Weber.

 

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and an academic freedom tempered by responsibility.

 

Salary and appointment terms

The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed with the relevant union. The period of employment is 3 years.

 

You can read more about career paths at DTU here.

 
Further information

Further information may be obtained from Professor Ákos T. Kovács, tel.: +45 4525 2527, atkovacs@dtu.dk  

 

Please do not send applications to this e-mail address; follow the electronic application and submission procedure as explained below.

 

You can read more about DTU Bioengineering on http://www.bioengineering.dtu.dk and a DTU podcast introduces the Center that is also described at www.cemist.dtu.dk.

 
Application

Please submit your online application no later than 25 March 2020 (23:59 local time).

 

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link “Apply online”, fill in the online application form, and attach all your materials in English in one PDF file. The file must include:

  • A letter motivating the application (cover letter) – please provide contact details for two referees in your motivation letter
  • Curriculum vitae
  • Grade transcripts and BSc/MSc diploma
  • Excel sheet with translation of grades to the Danish grading system (see guidelines and excel spreadsheet here)

Candidates may apply prior to obtaining their master’s degree, but cannot begin before having received it.


All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.

 

The Center for Microbial Secondary Metabolites aims to establish what effect microbial secondary metabolites have on other microorganisms in their natural environment. We have traditionally perceived them as ‘competition substances’, but in natural environments they are rarely produced in quantities of antibiotic effect. The Center’s hypothesis is that secondary metabolites constitute a network of signal molecules that directly affect gene expression, behaviour, and metabolism of the microorganisms and thus play a decisive role in the composition and function of microbiological communities. We will explore this in an interdisciplinary collaboration with the use of sequence-based, analytical-chemical, molecular, bioinformatic, and classic microbiological methods.

 

The Department of Biotechnology and Biomedicine (DTU Bioengineering) addresses challenges of societal and scientific importance within biotechnology, biomedicine, food technology and human health. The department is based on both basic and applied research and employs tools from biochemistry, biophysics, chemistry, cellular biology, immunology, microbial ecology and physiology, bioinformatics and bio-engineering. Research is conducted within three main areas: Microbial ecology and physiology, Industrial biotechnology and cell factories, and Biomedicine and health. The department has extensive collaboration with national and international research units and industries. DTU Bioengineering has approx. 300 employees, of which 2/3 is scientific staff. The department is located at DTU Lyngby Campus

 

Technology for people
DTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear vision to develop and create value using science and engineering to benefit society. That vision lives on today. DTU has 11,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. Our main campus is in Kgs. Lyngby north of Copenhagen and we have campuses in Roskilde and Ballerup and in Sisimiut in Greenland.

Deadline: 25 March 2020
Unit: DTU Bioengineering
Read the job description and apply online

Post expires on Wednesday March 25th, 2020

Postdoc in “GenoChild: Gene-based optimization of diagnosis, treatment and prevention of childhood obesity”

at Novo Nordisk Foundation Center for Basic Metabolic Research

University of Copenhagen

The University of Copenhagen seeks a highly motivated and talented postdoctoral fellow to commence October 1, 2020 at the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen.

The postdoctoral fellowship is part of the Novo Nordisk Foundation Center for Basic Metabolic Research International Postdoctoral Program www.cbmr.ku.dk/postdocprogram.

About Us
The Novo Nordisk Foundation Center for Basic Metabolic Research’s vision is to strengthen interdisciplinary research that transforms our basic understanding of the mechanisms that underlie metabolic health and disease, and to accelerate this knowledge toward new prevention and treatment strategies. We were established in 2010, and in 2017 we moved into new laboratories, offices and meeting rooms in the Maersk Tower www.maersktower.ku.dk.

The Center has around 200 employees who work in an international, highly collaborative research environment across a range of biomedical disciplines. You can read more about us here: www.cbmr.ku.dk.

Our Research
The postdoc position is in the Genomic Physiology and Translation Group headed by Professor Torben Hansen. The research group investigates the human genome and the human global microbiome to characterize the impact of these genomes on health and disease. The findings can lead to potent translational strategies for prevention and treatment of metabolic disease. You can read more about the Hansen Group at www.cbmr.ku.dk/research/human-genomics-and-metagenomics-in-metabolism/hansen-group.

The projects in the Hansen Group are interdisciplinary and often in close collaboration with both national and international partners.

Job Description

Childhood obesity is a major health challenge associated with several comorbidities (e.g. dyslipidemia, hypertension, insulin resistance, non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D)), which often tracks into adulthood, resulting in severe long-term consequences. Childhood obesity is a multifactorial disorder with a strong genetic component. Estimates of the heritability of BMI (the proportion of phenotypic variance of BMI, which is attributable to genetic factors) range between 47-90%. The precipitation of cardiometabolic comorbidities among obese children is likely due to the combined genetic effect of obesity and tissue and cell type specific other risk variants, i.e. risk variants for T2D or NAFLD. Recent studies suggest that polygenic risk scores (PRS) that integrate effects of a very large number of variants, including many that lack significant genomewide associations, can identify individuals with extreme levels of risk for disease, including obesity and T2D. Our ambition is to define tissue and cell type specific PRS to identify the subset of obese children who are i) at highest risk of progression to type 2 diabetes and ii) at highest risk of developing NAFLD. Furthermore, we will examine whether these children respond satisfactorily to a structured lifestyle intervention. The project focus on translation of information from tissue specific single cell RNA profiling and single cell ATAC seq to generate cell type specific PRS. The generated PRS will be examined in more than 6,000 deep phenotyped and genotyped children followed at the Pediatric Department of Holbæk University Hospital. Co-mentors will be Associate Professor and Group Leader at CBMR, Tune Pers and Chief Physician, Jens-Christian Holm, Holbæk University Hospital.

Profile

The fellowship is aimed at early career researchers with a basic science background or clinicians who aspire to a career in academic medicine. We are particularly interested in candidates who are familiar with integrative research approaches within the broad area of basic metabolic research with an application towards human pathophysiology.

Required qualifications:

  • PhD in Bioinformatics, Biology, Biochemistry, Molecular Biology, Molecular Biomedicine, or related sciences
  • Excellent scientific track record in relation to career stage
  • Profound knowledge of bioinformatics, biostatistics and/or computer science
  • Knowledge of metabolic disease, especially cardiometabolic traits related to obesity
  • Excellent English communication skills, both written and oral
     

Eligibility

The CBMR International Postdoctoral Program is open for applicants that hold a PhD degree awarded from a university outside of Denmark. The program is also open for applicants with a Danish PhD degree who can document at least 12 months full-time research experience from outside Denmark. You are not eligible to apply for the program if you have been employed in a postdoctoral position for more than one year at the University of Copenhagen prior to the commencement of the fellowship.

Terms of Employment

The employment as postdoc is a full-time position for 3 years. Starting date is October 1, 2020.

Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

Questions

For further information about the position, please contact Professor Torben Hansen at torben.hansen@sund.ku.dk. Questions regarding the CBMR International Postdoctoral Program must be directed to cbmr@sund.ku.dk. For questions regarding the recruitment procedure, please contact HR at sund-hr-cbmr@sund.ku.dk.

The University of Copenhagen International Staff Mobility office offers support and assistance to all international researchers on all issues related to moving to and settling in Denmark. Read more at www.ism.ku.dk.

Application Procedure

Your online application must be submitted in English via the ‘Apply now’ link below. Furthermore, your application must include the following documents/attachments – all in PDF format:

  • Cover letter expressing the motivation and previous research experience of the applicant (max 1 page)
  • Curriculum vitae
  • Copy of the PhD degree certificate and the Master degree certificate. In case the PhD has not yet been completed, a written statement from the supervisor is acceptable.
  • List of publications
  • References (name and contact details of at least two references)

 
Application Deadline: March 22, 2020, 23.59pm CET
 
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
 
The Further Process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
 
You can read about the recruitment process at www.employment.ku.dk/faculty/recruitment-process.
 
The applicant will be assessed according to the Ministerial Order no. 242 of March 13, 2012 on the Appointment of Academic Staff at Universities.
 
The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of their personal background.

Read the job description at the university homepage

Apply

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Post expires on Sunday March 22nd, 2020

One PhD position in biology

Ref SLU ua 2020.2.5.1-296

Department of Plant Breeding

Genetic improvement of the seedcake quality of rapeseed for high quality feed and food uses 

Accompanied by a changing climate and a growing population, we are facing major challenges in supply of food, industrial raw materials and energy to meet an increasing demand for bio-based raw materials while making plant production more environmentally friendly and energy-efficient. At the Department of Plant Breeding, SLU Alnarp, we perform research, education and innovative extension work that are of great strategic importance for solving the abovementioned challenges. We use a wide range of both conventional and modern breeding technologies, ranging from field experiments and evaluation of genetic diversity to genetic, omics-, biotechnological, biochemical and physiological approaches. We are now recruiting a motivated PhD student to the Department of Plant Breeding, SLU in Alnarp. This doctoral project is funded SLU Grogrund – Center for Plant Breeding of Food Crops, which will gather academia and industry to develop competences to ensure, in accordance with the objectives of the food strategy, the availability of varieties for sustainable and competitive agricultural and horticultural production throughout Sweden.

Description:

The aim of this PhD project is to improve the seed cake quality of rapeseed for high quality feed and food uses. Research activities include transcriptome analysis for searching for new candidate genes, functional analysis of candidate genes using CRISPR-CAs9 in combination with Agrobacterium transformation and protoplast infection, screening and evaluation of mutation lines from natural or TILLING populations by sequencing, and chemical analyses of mutation lines.

Qualifications:

We seek a highly motivated and devoted candidate with master degree in plant biology or equivalent, with competence in molecular biology and biotechnology.  Experience in tissue culture, plant transformation and genome editing is a merit. The applicant must be fluent in both written and spoken English.

Place of work:

Alnarp

Extent:

100% of employment for 4 years.                               

Starting date:

According to agreement.

Application:

We welcome your application no later than 2020-03-15, use the button below.

A person has basic eligibility for third cycle education if he or she has taken a second cycle qualification or has completed course requirements of at least 240 higher education credits, including at least 60 higher education credits at second cycle education. Upper secondary school grades equivalent to English B/English 6 are a basic requirement.

Selection among applicants meeting the requirements is made with reference to written application including curriculum vitae, copies of degrees and transcripts of academic records, one copy of the dissertation for masters or undergraduate degree, a list of at least two references familiar with the applicant’s qualifications, certified knowledge of the English language and an interview.

Please observe that applicant/s chosen to participate in an interview shall hand in certified true copies of certificates, diplomas and transcripts from previous studies at an internationally recognized higher education institution (university or university college) and transcripts in connection to the interview. If the applicant is a foreign citizen we require a certified copy of the page in your passport with your personal data and photography.

Read about the PhD education at SLU at www.slu.se/en/education/postgraduate-studies/

Academic union representatives:

https://internt.slu.se/en/my-employment/employee-associations/kontaktpersoner-vid-rekrytering/


The Swedish University of Agricultural Sciences (SLU) develops the understanding and sustainable use and management of biological natural resources. The university ranks well internationally within its subject areas. SLU is a research-intensive university that also offers unique degree programmes in for example rural development and natural resource management, environmental economics, animal science and landscape architecture.

SLU has just over 3,000 employees, 5,000 students and a turnover of SEK 3 billion. The university has invested heavily in a modern, attractive environment on its campuses in Alnarp, Umeå and Uppsala.

www.slu.se

SLU is an equal opportunity employer.

Contact person

Li-Hua Zhu

Professor

+46 (0)40 41 53 73

firstname.surname@slu.se

Read the job description at the university homepage

Apply

Post expires on Sunday March 15th, 2020

Phd position in silviculture with focus on Scots pine and thinning

Ref SLU.ua.2020.2.5.1-587

Southern Swedish Forest Research Centre

SLU is one of the world’s top ten universities in biodiversity conservation and soil science, and is ranked #1 in forestry (CWUR). At our centre we carry out research, teaching and dissemination of scientific findings with direct application to the sustainable management of forests. We are a multidisciplinary institution, with global relevance and specialized expertise on issues related to dynamic forest landscapes. We closely collaborate with multiple stakeholders and conduct applied research in forest ecology, silviculture, pathology, policy and planning. We teach bachelor, master’s and PhD level courses addressing all of these subject areas. 

Silviculture with focus on Scots pine and thinning 

Description:

The aim of the PhD student position is a doctoral degree. In this project the student will primarily do research in silviculture of Scots pine in boreal forestry. The project will focus on growth and yield, and specifically the tree and stand response to thinnings. The main core of research work will be to analyze data from long term experiments and dealing with ecophysiological concepts of tree growth. The project is part of a larger interdisciplinary collaboration project between SLU and Stora Enso which will comprise about 5 doctoral students and several researchers who will have joint activities. They will also gain good insight into the work of an international company working with the entire value chain from forest production to finished bio-based product. The postgraduate education will be coordinated with trainee activities within Stora Enso. 

Qualifications:

The applicant should have a M. Sc. degree in silviculture or related forest sciences, biostatistics or a related discipline but with main focus on understanding tree and stand growth and development. Other beneficial qualifications are experience of forestry analytics, using preferably R programming language and/or GIS software, and good communications skills with fluency in written English. Drivers’ license is a necessity for the work duties.

The application must contain: A letter with expectations on the position and what you personally find interesting within the silviculture research subject (max 1 page), CV and contact information to two reference persons. the qualifications needed for the position; desired education, experience and personal traits. Be clear on what is required and what is a merit.

Place of work:

Alnarp

Forms for funding or employment:

Employment (4 years)

Starting date:

2020-05-01 or according to agreement

Application:

We welcome your application no later than 2020-03-16, use the button below.

A person has basic eligibility for third cycle education if he or she has taken a second cycle qualification or has completed course requirements of at least 240 higher education credits, including at least 60 higher education credits at second cycle education. Upper secondary school grades equivalent to English B/English 6 are a basic requirement.

Selection among applicants meeting the requirements is made with reference to written application including curriculum vitae, copies of degrees and transcripts of academic records, one copy of the dissertation for masters or undergraduate degree, a list of at least two references familiar with the applicant’s qualifications, certified knowledge of the English language and an interview.

Please observe that applicant/s chosen to participate in an interview shall hand in certified true copies of certificates, diplomas and transcripts from previous studies at an internationally recognized higher education institution (university or university college) and transcripts in connection to the interview. If the applicant is a foreign citizen we require a certified copy of the page in your passport with your personal data and photography.

Read about the PhD education at SLU at www.slu.se/en/education/postgraduate-studies/

Academic union representatives:

https://internt.slu.se/en/my-employment/employee-associations/kontaktpersoner-vid-rekrytering/


The Swedish University of Agricultural Sciences (SLU) develops the understanding and sustainable use and management of biological natural resources. The university ranks well internationally within its subject areas. SLU is a research-intensive university that also offers unique degree programmes in for example rural development and natural resource management, environmental economics, animal science and landscape architecture.

SLU has just over 3,000 employees, 5,000 students and a turnover of SEK 3 billion. The university has invested heavily in a modern, attractive environment on its campuses in Alnarp, Umeå and Uppsala.

www.slu.se

SLU is an equal opportunity employer.

Contact person

Emma Holmström

+46 (0)40-415114

firstname.surname@slu.se

Read the job description at the university homepage

Apply

Post expires on Monday March 16th, 2020

Post doctoral position in Governance of Nature-based Solutions – part of EU-CONEXUS project

Ref SLU ua 2020.2.5.1-437

Department of Landscape Architecture, Planning and Management

The Department of Landscape Architecture, Planning and Management is part of the faculty for Landscape Planning, Horticulture and Agricultural Sciences. Teaching and research responsibilities of the department cover six thematic areas: landscape planning, landscape analysis, governance and management, urban vegetation, cultural heritage, and design of urban landscapes. Teaching and research are multidisciplinary, including the perspectives of the humanities, social sciences, natural sciences, and technology. Of special concern is the development of action-oriented knowledge about society and sustainable urban environments through studies of planning and design practices. The department’s staff comprises 80 members, active in both teaching and research.

Duties:

The PostDoc position is part of a larger EU funded project (CONEXUS) focusing on strengthening international cooperation on sustainable urbanization by the use of nature-based solutions (NBS), as well as strengthening collaboration between European (EU) countries and Community of Latin American and Caribbean (CELAC) states.

CONEXUS is a consortium of EU and CELAC partners, including research partners, NGO’s and seven large cities. The cities share common challenges of sustainable urbanization and the PostDoc will be part of coordinating the development of local ‘Life-Lab’ partnerships in each of the partner cities. This includes participatory engagement to identify, initiate and co-create NBS interventions locally in Europe and South America.

In addition to being engaged within CONEXUS (50%) the PostDoc will also develop own research in relation to the topic of landscape governance, as well as being engaged in developing and contributing to various educational activities.

Qualifications:

As postdoctoral appointments are career-developing positions for junior researchers, we are primarily looking for candidates with a doctoral degree that is three years old at most.

Required:

  • PhD completed in landscape architecture, geography, ecology, social sciences or related field
  • Demonstrated research experience on the topics of planning and/or governance in relation to green infrastructure and nature-based solutions
  • Excellent written and oral English communication skills
  • Good written and oral Spanish communication skills
  • Effective inter- and intrapersonal communication skills

Desired:

  • Demonstrated experience in engaging diverse stakeholders (e.g., industry, government, academics and landholders)
  • Experience from international project
  • Experience of project management
  • Teaching experience at academic level

Place of work:

Alnarp, Sweden

Form of employment:

Temporary employment, 24 months

Extent:

100%

Starting date:

According to agreement.

Application:

We welcome your application no later than 2020-03-23, use the button below.

Academic union representatives:

https://internt.slu.se/en/my-employment/employee-associations/kontaktpersoner-vid-rekrytering/


The Swedish University of Agricultural Sciences (SLU) develops the understanding and sustainable use and management of biological natural resources. The university ranks well internationally within its subject areas. SLU is a research-intensive university that also offers unique degree programmes in for example rural development and natural resource management, environmental economics, animal science and landscape architecture.

SLU has just over 3,000 employees, 5,000 students and a turnover of SEK 3 billion. The university has invested heavily in a modern, attractive environment on its campuses in Alnarp, Umeå and Uppsala.

www.slu.se

SLU is an equal opportunity employer.

Contact person

Thomas Randrup

Professor

+4640-415412

firstname.surname@slu.se

Märit Jansson

senior lecturer

+4640 415135

firstname.surnamen@slu.se

Read the job description at the university homepage

Apply

Post expires on Monday March 23rd, 2020

Postdoc in microfluidics-based in vitro modeling of the tumor microenvironment

Postdoc in microfluidics-based in vitro modeling of the tumor microenvironment
Department of Biology
Faculty of Science
University of Copenhagen

A 2-year postdoctoral position is open from June 1st 2020 or as soon as possible thereafter, in the project MICROGRAD: A new generation of microfluidics-based methods to study genetic and functional effects of complex spatiotemporal gradients in tumor microenvironments.

Research environment  
The project is a highly interdisciplinary collaboration between four groups, located at the Department of Biology, Faculty of Science (Prof. Stine F. Pedersen, Prof. Albin Sandelin), the Technical University of Denmark (Assoc. Prof. Rodolphe Marie) and Federal Institute for Materials Research and Testing, Berlin (Prof. Ute Resch-Genger). The candidate will be based in Stine F. Pedersen’s group, but will work closely with the other groups, especially two postdoctoral fellows hired in parallel in the Sandelin and Marie groups. Together, the groups employ multiple postdocs, PhD students, and undergraduate students and provide a strong, international research environment.  

Research project and postdoc qualifications
The tumor microenvironment fundamentally impacts tumor cell behavior, but cannot currently be accurately mimicked in vitro. This project will develop and apply a new generation of microfluidic devices that allow constitution of spatiotemporally precise gradients of acidosis and hypoxia, key properties of the tumor microenvironment. The devices will be validated using fluorescent reporters, and will be used to determine the phenotypic and genotypic responses of tumor cells to the tumor microenvironment.

The postdoc will be responsible for all work on this project in the Pedersen lab and for coordinating the close collaboration with the three other groups. The ideal candidate has a background in biophysics/cell biology and strong expertise in advanced imaging. Expertise in molecular biology approaches and/or cancer biology is an advantage.

Other essential requirements are a PhD in a life science field, a documented track record of strong scientific publications, and excellent written and spoken English. The candidate must be able to work autonomously as well as in a team and have a passion for working in a highly interdisciplinary environment.  

Further information on the Department is linked at http://www.science.ku.dk/english/about-the-faculty/organisation/.  Inquiries about the position can be made to Professor Stine F. Pedersen (sfpedersen@bio.ku.dk).

The University wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

Terms of employment
The position is covered by the Memorandum on Job Structure for Academic Staff.

Terms of appointment and payment accord to the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State.

The starting salary is currently up to DKK 434.179 including annual supplement (+ pension up to DKK 74.244). Negotiation for salary supplement is possible.[SHFP1] 

The application, in English, must be submitted electronically by clicking APPLY NOW below.

Please include

  • Cover letter
  • Curriculum vita
  • Diplomas (Master and PhD degree or equivalent)
  • Complete publication list
  • Separate reprints of 3 particularly relevant papers

The deadline for applications is March 25 2020, 23:59 GMT +1.

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Interview Committee.

You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.

Apply now

Read the job description at the university homepage.

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Post expires on Wednesday March 25th, 2020

Postdoc in Human Genomics

Novo Nordisk Foundation Center for Basic Metabolic Research

University of Copenhagen

The University of Copenhagen seeks a highly motivated and talented postdoctoral fellow to commence October 1, 2020 at the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen.

The postdoctoral fellowship is part of the Novo Nordisk Foundation Center for Basic Metabolic Research International Postdoctoral Program www.cbmr.ku.dk/postdocprogram.

About Us
The Novo Nordisk Foundation Center for Basic Metabolic Research’s vision is to strengthen interdisciplinary research that transforms our basic understanding of the mechanisms that underlie metabolic health and disease, and to accelerate this knowledge toward new prevention and treatment strategies. We were established in 2010, and in 2017 we moved into new laboratories, offices and meeting rooms in the Maersk Tower www.maersktower.ku.dk.

The Center has around 200 employees who work in an international, highly collaborative research environment across a range of biomedical disciplines. You can read more about us here: www.cbmr.ku.dk.

Our Research
The research group of Associate Professor Niels Grarup investigates the genetic architecture of type 2 diabetes and metabolic traits to expand our insights into pathogenesis of metabolic disease. Our vision is to define the genetic determinants of diabetes-related phenotypes and to translate this information to clinically relevant interventions. Other methods include genetic epidemiology studies of populations or diseases and the application of recall-by-genotype principles to investigate the physiological impact on specific genetic variations. In addition, we participate in a number of genetics consortia in international collaborative studies on obesity, type 2 diabetes and related traits applying genome-wide association or other up-to-date genetic-epidemiological methods. The research group is embedded in a highly international and interdisciplinary environment that includes medical doctors, bioinformaticians and molecular biologists. The group has a diverse composition and we strive for a supportive and inclusive environment.

Job Description

In this study, we will examine the genetic aspects of taste preference to improve our understanding of taste, dietary habits and the effects of overconsumption on health status. As taste preference has a strong impact on food choice, it is important to investigate the genetic facets of an otherwise behavioral concept. Your tasks will be to lead the project, to help in further developing questionnaires to interrogate human taste preference and to run and interpret large-scale genetic analysis in collaboration with other scientists in the group. The project is carried out in collaboration with national and international partners.

Profile

The fellowship is aimed at early career researchers with a basic science background or clinicians who aspire to a career in academic medicine. We are particularly interested in candidates who are familiar with integrative research approaches within the broad area of basic metabolic research with an application towards human pathophysiology.

Required qualifications:

  • PhD in Biology, Biochemistry, Molecular Biology, Molecular Biomedicine, or related sciences
  • Excellent scientific track record in relation to career stage
  • Profound knowledge of human genetics in relation to human diseases and physiology
  • Knowledge of human nutrition, metabolism and diabetes
  • Experience with analysing human genetics data (NGS and/or GWAS) in relation to quantitative and/or disease traits
  • Demonstrated capacity for coordinating and supporting effective team work
  • Excellent English communication skills, both written and oral

Eligibility

The CBMR International Postdoctoral Program is open for applicants that hold a PhD degree awarded from a university outside of Denmark. The program is also open for applicants with a Danish PhD degree who can document at least 12 months full-time research experience from outside Denmark. You are not eligible to apply for the program if you have been employed in a postdoctoral position for more than one year at the University of Copenhagen prior to the commencement of the fellowship.

Terms of Employment

The employment as postdoc is a full-time position for 3 years. Starting date is October 1, 2020.

Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

Questions

For further information about the position, please contact Associate Professor Niels Grarup at niels.grarup@sund.ku.dk. Questions regarding the CBMR International Postdoctoral Program must be directed to cbmr@sund.ku.dk. For questions regarding the recruitment procedure, please contact HR at sund-hr-cbmr@sund.ku.dk.

The University of Copenhagen International Staff Mobility office offers support and assistance to all international researchers on all issues related to moving to and settling in Denmark. Read more at www.ism.ku.dk.

Application Procedure

Your online application must be submitted in English via the ‘Apply now’ link below. Furthermore, your application must include the following documents/attachments – all in PDF format:

  • Cover letter expressing the motivation and previous research experience of the applicant (max 1 page)
  • Curriculum vitae
  • Copy of the PhD degree certificate and the Master degree certificate. In case the PhD has not yet been completed, a written statement from the supervisor is acceptable.
  • List of publications
  • References (name and contact details of at least two references)

Application Deadline: March 22, 2020, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
 
The Further Process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
 
You can read about the recruitment process at www.employment.ku.dk/faculty/recruitment-process.
 
The applicant will be assessed according to the Ministerial Order no. 242 of March 13, 2012 on the Appointment of Academic Staff at Universities.

Apply now

Read the job description at the university homepage


 
The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of their personal background.

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Post expires on Sunday March 22nd, 2020

Postdoc in Adipose G protein-coupled receptor signalling

Novo Nordisk Foundation Center for Basic Metabolic Research

University of Copenhagen

The University of Copenhagen seeks a highly motivated and talented postdoctoral fellow to commence October 1, 2020 at the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen.

The postdoctoral fellowship is part of the Novo Nordisk Foundation Center for Basic Metabolic Research International Postdoctoral Program www.cbmr.ku.dk/postdocprogram.

About Us
The Novo Nordisk Foundation Center for Basic Metabolic Research’s vision is to strengthen interdisciplinary research that transforms our basic understanding of the mechanisms that underlie metabolic health and disease, and to accelerate this knowledge toward new prevention and treatment strategies. We were established in 2010, and in 2017 we moved into new laboratories, offices and meeting rooms in the Maersk Tower www.maersktower.ku.dk.

The Center has around 200 employees who work in an international, highly collaborative research environment across a range of biomedical disciplines. You can read more about us here: www.cbmr.ku.dk.

Our Research
We are focused on understanding the mechanisms controlling adipose tissue metabolism and how this control shapes organismal energy homeostasis. Specifically, we view the adipocyte as a signalling hub that receives and integrates a diverse array of neuronal, metabolite, and hormonal cues. These signals collectively shape adipocyte biology and match metabolic output to balance systemic energy demands. Brown and beige adipocytes are types of fat cells that possess a profound capacity to expend energy and are classified more generally as thermogenic adipocytes. This calorie-burning capacity is particularly appealing as a potential therapeutic approach to counteract metabolic disease. However, we currently lack the means of safely harnessing thermogenic adipose activity.

In this project, we will directly address this gap-in-knowledge by exploring novel mechanisms of G protein-coupled receptor (GPCR) control of human thermogenic adipose in close collaboration with Professor Erik Richter, Associate Professor Steen Larsen, Associate Professor Camilla Schéele, and Professor Thue Schwartz at the University of Copenhagen. We will take advantage of a battery of interdisciplinary, big data approaches to identify candidate regulators. We will then apply state-of-the-art phenotyping and pharmacological strategies to characterize the physiological role of such candidates in adipose metabolism. Where possible, we will leverage our basic research findings toward the development of novel innovative treatment strategies.

Find out more about the Gerhart-Hines lab here: https://cbmr.ku.dk/research/nutrient-and-metabolite-sensing/gerhart-hines-group/

Job Description

We seek an enthusiastic, passionate scientist with medical training who is interested in applying their expertise to the discovery and characterization of new adipose GPCR signalling mechanisms. You will have the opportunity to learn and apply a variety of clinical techniques, such as tissue microdialysis sampling. You will interrogate candidate GPCR signalling in mouse and human adipocytes as well as adipose-specific mouse models using an array of pharmacological and metabolic phenotyping strategies.

Profile

The fellowship is aimed at early career researchers with a basic science background or clinicians who aspire to a career in academic medicine. We are particularly interested in candidates who are familiar with integrative research approaches within the broad area of basic metabolic research with an application towards human pathophysiology.

Required qualifications:

  • Ph.D. in Biology, Biochemistry, Molecular Biology, Molecular Biomedicine, or related sciences
  • M.D.
  • Excellent scientific track record in relation to career stage
  • Profound knowledge of adipose tissue biology and metabolic disease
  • Knowledge of GPCR signalling and pharmacology
  • Experience with writing clinical protocols and biopsy techniques (such as the Bergström method)
  • Excellent English communication skills, both written and oral

Eligibility

The CBMR International Postdoctoral Program is open for applicants that hold a PhD degree awarded from a university outside of Denmark. The program is also open for applicants with a Danish PhD degree who can document at least 12 months full-time research experience from outside Denmark. You are not eligible to apply for the program if you have been employed in a postdoctoral position for more than one year at the University of Copenhagen prior to the commencement of the fellowship.

 Terms of Employment

The employment as postdoc is a full-time position for 3 years. Starting date is October 1, 2020.

Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

Questions

For further information about the position, please contact Associate Professor Gerhart-Hines at zpg@sund.ku.dk. Questions regarding the CBMR International Postdoctoral Program must be directed to cbmr@sund.ku.dk. For questions regarding the recruitment procedure, please contact HR at sund-hr-cbmr@sund.ku.dk.

The University of Copenhagen International Staff Mobility office offers support and assistance to all international researchers on all issues related to moving to and settling in Denmark. Read more at www.ism.ku.dk.

Application Procedure

Your online application must be submitted in English via the ‘Apply now’ link below. Furthermore, your application must include the following documents/attachments – all in PDF format:

  • Cover letter expressing the motivation and previous research experience of the applicant (max 1 page)
  • Curriculum vitae
  • Copy of the PhD degree certificate and the Master degree certificate. In case the PhD has not yet been completed, a written statement from the supervisor is acceptable.
  • List of publications
  • References (name and contact details of at least two references)

 Application Deadline: March 22, 2020, 23.59pm CET
 
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
 
The Further Process

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
 
You can read about the recruitment process at www.employment.ku.dk/faculty/recruitment-process.
 
The applicant will be assessed according to the Ministerial Order no. 242 of March 13, 2012 on the Appointment of Academic Staff at Universities.

Apply now

Read the job description at the university homepage.
 
The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of their personal background.

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Post expires on Sunday March 22nd, 2020

Postdoc in Organ Cross-Talk / Tissuekines

Novo Nordisk Foundation Center for Basic Metabolic Research

University of Copenhagen

The University of Copenhagen seeks a highly motivated and talented postdoctoral fellow to commence October 1, 2020 at the Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen.

The postdoctoral fellowship is part of the Novo Nordisk Foundation Center for Basic Metabolic Research International Postdoctoral Program www.cbmr.ku.dk/postdocprogram.

About Us
The Novo Nordisk Foundation Center for Basic Metabolic Research’s vision is to strengthen interdisciplinary research that transforms our basic understanding of the mechanisms that underlie metabolic health and disease, and to accelerate this knowledge toward new prevention and treatment strategies. We were established in 2010, and in 2017 we moved into new laboratories, offices and meeting rooms in the Maersk Tower www.maersktower.ku.dk.

The Center has around 200 employees who work in an international, highly collaborative research environment across a range of biomedical disciplines. You can read more about us here: www.cbmr.ku.dk.

Our Research
The general focus of the “Organ Cross-Talk / Tissuekines” group is the study of the intercellular communications and molecular pathways controlling metabolic functions that are associated with the development of metabolic diseases such as obesity and type 2 diabetes. We apply interdisciplinary approaches combining non-biased and high throughput technologies with functional characterization using gene manipulation techniques, cellular biology and physiology experiments in various cells, tissues and animal models, to identify novel factors and pathways that regulate metabolic processes. Our ultimate goal is to define novel specific targets that can be manipulated to improve outcomes in metabolic diseases.

The successful candidate will benefit from a dynamic, internationally diverse, collaborative and stimulating scientific environment in a well-equipped laboratory.

More information at: https://cbmr.ku.dk/research/integrative-metabolism-and-environmental-influences/emanuelli-group/

Job Description

We are seeking a highly motivated and qualified fellow with a background in molecular and cellular biology to investigate the molecular mechanisms regulating the activity of thermogenic adipocytes. The project aims to mechanistically dissect the functions of a key DNA- and RNA-binding protein (DRBP) in promoting and maintaining the thermogenic capacity of adipocytes. In collaboration with groups at the CBMR and internationally, the postdoctoral fellow will use a multidisciplinary approach combining RNA/protein complex purification, OMICS technologies and a wide range of biological assays using gain- and loss-of function studies in mouse and human adipocytes to decipher the molecular mechanisms controlled by this DRBP to facilitate the metabolic functions of thermogenic adipocytes.

Profile

The fellowship is aimed at early career researchers with a basic science background or clinicians who aspire to a career in academic medicine. We are particularly interested in candidates who are familiar with integrative research approaches within the broad area of basic metabolic research with an application towards human pathophysiology.

Required qualifications:

  • PhD in Biology, Biochemistry, Molecular Biology, Molecular Biomedicine, or related sciences
  • Excellent scientific track record in relation to career stage
  • Profound knowledge of molecular and cellular biology, in particular of the regulation of gene expression and RNA processing
  • Knowledge of cellular metabolism
  • Experience with cell culture, immunoblotting, gene transfer or silencing, gene expression analysis, protein complex purification, ChIP
  • Excellent English communication skills, both written and oral
  • Demonstrated capacity for effective team work

Eligibility

The CBMR International Postdoctoral Program is open for applicants that hold a PhD degree awarded from a university outside of Denmark. The program is also open for applicants with a Danish PhD degree who can document at least 12 months full-time research experience from outside Denmark. You are not eligible to apply for the program if you have been employed in a postdoctoral position for more than one year at the University of Copenhagen prior to the commencement of the fellowship.

Terms of Employment

The employment as postdoc is a full-time position for 3 years. Starting date is October 1, 2020.

Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Depending on qualifications, a supplement may be negotiated.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

Questions

For further information about the position, please contact Associate Professor Brice Emanuelli at emanuelli@sund.ku.dk. Questions regarding the CBMR International Postdoctoral Program must be directed to cbmr@sund.ku.dk. For questions regarding the recruitment procedure, please contact HR at sund-hr-cbmr@sund.ku.dk.

The University of Copenhagen International Staff Mobility office offers support and assistance to all international researchers on all issues related to moving to and settling in Denmark. Read more at www.ism.ku.dk.

Application Procedure

Your online application must be submitted in English via the ‘Apply now’ link below. Furthermore, your application must include the following documents/attachments – all in PDF format:

  • Cover letter expressing the motivation and previous research experience of the applicant (max 1 page)
  • Curriculum vitae
  • Copy of the PhD degree certificate and the Master degree certificate. In case the PhD has not yet been completed, a written statement from the supervisor is acceptable.
  • List of publications
  • References (name and contact details of at least two references)

Application Deadline: March 22, 2020, 23.59pm CET
 
We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.
 
The Further Process

After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed, each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.
 
You can read about the recruitment process at www.employment.ku.dk/faculty/recruitment-process.
 
The applicant will be assessed according to the Ministerial Order no. 242 of March 13, 2012 on the Appointment of Academic Staff at Universities.

Apply now

Read the job description at the university homepage
 
The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of their personal background.

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Post expires on Sunday March 22nd, 2020

Post-doc position: Carbohydrate polymers – proteins interactions Malmo

Ref REK2020/29

About Malmö University
Malmö University is an innovative, urban and international institute of higher education, located in the center of Malmö. We have around 1 800 employees and about 25 000 students and thereby one of Sweden’s largest universities. Our research and education are characterized by the role we believe a university should play in an open society, which is to contribute to sustainability and equality in a scientifically grounded way with external partners and stakeholders. Identifying and addressing the challenges of the future are of highest priority. Our researchers and students work in collaboration to create, share and spread knowledge in order to understand, explain and develop society. 

Malmö University is organized into five faculties: Faculty of Health and Society, Culture and Society, Education and Society, Faculty of Odontology and Technology and Society. 

Faculty of Health and Society
Our education and research are conducted with the vision of promoting health and participation. The faculty conducts research that   focuses on societal problems and seeks solutions in several fields of research. We develop leading professional education programs that provide healthcare, social work and enterprises with competent staff. Our education and research are located in three locations in Malmö. 

Biofilms – Research Center for Biointerfaces
The present position will be a part of the research center Biofilms – Research Center for Biointerfaces, which is a large academic environment at Malmö University spanning several departments. The overall objective of Biofilms – Research Center for Biointerfaces is to produce high-quality front-line research within the biomedical field, to offer relevant and attractive educational programs, and to maintain good reciprocal relations with partner industries and the public sector. The center today comprises four research groups (60 researchers) and offers a translational network for applied research, in collaboration with regional industry. The center expertise covers the range from mathematical modelling to clinical sciences. 

About the position
Protein-based therapeutics are becoming increasingly popular in medicine. Compared to low molecular drugs, they are more specific, cause fewer side effects and are environmentally friendly. They are however more sensitive to the conditions of the surroundings and need to be specially formulated to preserve their structure and function. Another challenge in designing protein formulations is to provide slow release of proteins during extended time. In this project we will investigate interactions of proteins with carbohydrate – based drug delivery vehicles: starch microparticles. In the excess of water, proteins partition between starch microparticles and surrounding liquid. We explore different approaches for controlling the release rate of proteins from starch microparticles.

To stabilize proteins in the formulations they can be dried. In the absence of excipients, the proteins can however change their structure, which may influence their stability. In this part of the project, we will perform studies of structure of proteins imbedded in starch microparticles in the solid state. Furthermore, mechanisms of destabilization of proteins in the solid state and the effects of residual moisture will be investigated. The project will be performed in collaboration between Malmö University and two companies: Magle Chemoswed and Adroit Science.

Apart from carrying out research within these areas the applicant is expected to take responsibility for the maintenance of the instruments involved and to be active by supervising graduate and postgraduate students and fellow scientists in the techniques and participate in teaching at graduate and postgraduate levels. In addition, the applicant will be expected to take part in applications for external funding to support research activities.

Qualifications
A postdoc is primarily employed to conduct research. They have completed a doctoral degree or a foreign degree considered on par with a doctoral degree. This is primarily relevant to people who have completed their doctoral degree no less than three years before the application period for the position of postdoc has expired.

Specific requirements for this position
PhD degree in physical chemistry, biochemistry, biophysics, polymer chemistry, physical pharmacy or another relevant discipline

Highly valued requirements for this position:
Hands-on experience in some of the following methods: small- and wide-angle X-ray diffraction/scattering and other scattering techniques, calorimetry and thermal analysis (DSC, ITC, isothermal microcalorimetry, TGA), water sorption techniques, solution or solid-state NMR.

The ideal candidate should also have the ability to work in a team and collaborate with people in complementary disciplines.

Assessment criteria

  • The quality and focus of the doctoral thesis
  • Research activities within fields relevant to the appointment in question
  • Documented ability to independently conduct research of sufficient standard
  • Reflective presentation of their own pedagogical outlook and practices
  • Demonstrated ability to communicate and collaborate with actors in other parts of society with a connection to education and research

For more information contact
Vitaly Kocherbitov, Professor at the Department of Biomedical Science. Phone: +46 40 6657946, E-mail: Vitaly.Kocherbitov@mau.se

Form of employment and starting date
Temporary position for 12 months (full-time) starting from April 1st or as soon as possible thereafter. The position can be prolonged beyond the first year. At Malmö University, individual salary negotiations apply.

Malmö University is a workplace characterized by an open and inclusive approach where equal treatment adds value to our activities.

Application
You apply through Malmö University’s recruitment system by clicking the button “apply/ansök”. You have the responsibility that your application is complete according to the adverted position and your application must be received no later than March 1, 2020.

The application should contain the following:

  1. A brief summary of scientific, teaching and other qualifications relevant to the position
  2. Attested copies of certificates
  3. Curriculum Vitae (CV)
  4. List of scientific publications and developed teaching materials
  5. Copies of three of your most relevant scientific publications
  6. At least two letters of reference

Trade union representatives
SACO-S: Ann-Mari Campbell, ann-mari.campbell@mau.se
Lärarförbundet: Carl-Erik Blomberg, carl-erik.blomberg@mau.se
OFR/S (ST): Naser Eftekharian, naser.eftekharian@mau.se

Welcome with your application!

Read the job description at the university homepage

Apply

Post expires on Sunday March 1st, 2020

Post-doc/Researcher position: Broken Barriers – How to maintain skin health and avoid a defective barrier Malmo

Ref REK2020/20

About Malmö University
Malmö University is an innovative, urban and international institute of higher education, located in the centre of Malmö. We have around 1,800 employees and 24,000 students. Malmö University is organized into five faculties: Faculty of Health and Society, Culture and Society, Education and Society, Faculty of Odontology and Technology and Society. 

The Department of Biomedical Science, Faculty of Health and Society, offers a programme leading to a professional qualification, Biomedical Scientist (first cycle, 180 credits), and a Masters’ programme, Biomedical Surface Science (second cycle, 120 credits), as well as first and second cycle freestanding courses. The Department negotiates the multifaceted intersection between biology, chemistry, medicine, physics, and technology and the interdisciplinary approach to research and education aims to further the theoretical and practical understanding of the complex subject matter. Drawing on the balance between pure and applied research, the Department has been successful in attracting funding from regional, national, and international research funding bodies. 

The research at the faculty is also linked to the research center Biofilms – Research Center for Biointerfaces, which combines biomedical science with clinical and translational research in medical, dental, food and environmental application areas in close collaboration with regional industry.

About the position
The research activities will be conducted in a network of academic, industrial, and clinical partners within a newly funded project entitled Biobarriers – Health, Disorders and Healing. The general vision of the research project is to improve health and healing of biological barriers by modernizing clinical treatments and products based on molecular level knowledge. In particular, the aim of the open position is to investigate how knowledge of molecular and structural characteristics of skin, manipulated by formulations, can be translated into clinical treatments and industrial products for maintaining skin health and preventing deterioration and breaking of the skin barrier.

The outermost layer of the skin organ is called the stratum corneum (SC) and is responsible for the skin barrier, which effectively restricts both inward and outward diffusion of most molecules and thus upholds the water balance and protects us from harmful substances entering the body. The SC is normally exposed to dry and cold climate of the external environment. Therefore, it is perhaps not surprising that the natural moisturizing factor (NMF) is produced spontaneously in the skin barrier. These molecules are known to be beneficial for dry skin and certain skin diseases, such as winter xerosis and atopic dermatitis. We have previously shown that addition of this kind of molecules to the skin alters the molecular mobility of the SC lipid and protein components by retaining the dynamical properties associated with a more hydrated SC membrane at dehydrating conditions. Thus, by retaining the fluidity of the SC components on a molecular level, at reduced hydration conditions, NMF molecules can potentially act to maintain a healthy, soft, and pliable skin barrier.

This hypothesis will be investigated in more detail within this research project by investigating a selection of scientifically and commercially relevant excipients and/or active pharmaceutical ingredients (APIs). The main goal is to clarify the relationship between:

1. the permeability behavior of topically applied excipients/APIs at specified concentrations and characterization of their concentrations in the SC and the basal layer where viable keratinocytes reside,
2. the effect of excipients/APIs on the molecular properties of the SC components (e.g. molecular mobility and structural arrangements of keratin filaments and extracellular lipids), and
3. the effect of excipients/APIs at relevant concentrations (as determined from permeability studies) on cultured keratinocytes.

This relationship is key for understanding what kind of mechanisms that are important for maintaining a healthy skin organ and how to avoid factors and events leading to a defective barrier. With increased understanding of this relationship, it will be possible to explore the beneficial effects of excipients and/or APIs in a scientifically robust manner.

Notably, the work is expected to include both in vitro and in vivo methodology where pig skin is used as in vitro model for human skin, while examination of human skin in vivo is conducted on healthy or diseased human subjects after granted ethical permission; documented writing and approval of ethical permissions is therefore a valued benefit for the applicant. Further, considering that the project requires collaboration between academic, industrial, and clinical partners, it is expected that the applicant actively communicates and collaborate within this context; documented project management and leadership abilities are therefore valued.

Apart from carrying out research within these areas the applicant is expected to take responsibility for the maintenance of the instruments involved and to be active by supervising graduate and postgraduate students and fellow scientists in the techniques and participate in teaching at graduate and postgraduate levels. In addition, the applicant will be expected to take part in applications for external funding to support research activities. 

Qualifications
A postdoc is primarily employed to conduct research. They have completed a doctoral degree or a foreign degree considered on par with a doctoral degree. This is primarily relevant to people who have completed their doctoral degree no less than three years before the application period for the position of postdoc has expired.

Specific requirements
Candidates must hold a PhD in chemistry, chemical engineering, biophysics or a similar field.

Highly valued requirements
The ideal candidate holds a Master’s degree in chemistry, biochemistry or biophysics and has completed a doctoral education focusing on the skin barrier and/or topical or transdermal drug delivery.

Hands-on experience in some of the following methods is highly valued:

  • in vitro permeability studies with Franz cells or similar,
  • in vivo characterization of the skin barrier (e.g. TEWL, corneometry, tape-stripping, electrochemical measurements, etc.),
  • solution or solid-state NMR,
  • small- and wide-angle X-ray diffraction/scattering,
  • HPLC with spectrophotometry and/or mass spectroscopy detection.

 Assessment criteria

  • The quality and focus of the doctoral thesis
  • Research activities within fields relevant to the appointment in question
  • Documented ability to independently conduct research of sufficient standard
  • Reflective presentation of their own pedagogical outlook and practices
  • Demonstrated ability to communicate and collaborate with actors in other parts of society with a connection to education and research

Information
For more information contact Sebastian Björklund, +46 (0)40 6657891, Sebastian.Bjorklund@mau.se

Application
You apply through Malmo Universities’ recruitment system by clicking the button “apply/ansok”. It is your own responsibility that your application is complete with all required documentation according to the adverted position.

Please submit your application no later than March 1, 2020.
The candidate selected for this position must be able to meet eligibility requirements to work in Sweden at  the start of the appointment.

The application should contain the following: 

1. Cover letter with a motivation for applying to this position
2. A brief summary of scientific, teaching, and other qualifications relevant to the position
3. Attested copies of certificates
4. Curriculum Vitae (CV)
5. List of scientific publications and developed teaching materials
6. Copy of doctoral dissertation or equivalent.
7. Copies of three of your most relevant scientific publications
8. At least two references with names, titles/positions, relation to you, and contact information.


Form of employment and starting date
At least one-year position, starting as soon as possible. At Malmö University, individual salary negotiations apply. Full-time 

Starting date 
as soon as possible

Trade union representatives
SACO-S: Ann-Mari Campbell, ann-mari.campbell@mau.se
Lärarförbundet: Carl-Erik Blomberg, carl-erik.blomberg@mau.se
OFR/S (ST): Naser Eftekharian, naser.eftekharian@mau.se

Welcome with your application!

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Post expires on Sunday March 1st, 2020

Postdoc in Vascular Biology at Department of Biomedical Sciences

We are looking for a highly motivated and dynamic researcher for a 2 year postdoc position commencing in May 2020 who will investigate the role of microtubules in hypertension.

The fellow will study the molecular contribution of the microtubule network to hypertension in arteries using the state-of-the-art techniques including, but not limited to, isometric and pressure myography, gene knockdown/editing systems, confocal/super-resolution microscopy, in situ proximity ligation assays, and animal disease models.

Information on the department can be found at: https://bmi.ku.dk/english/research/the-vascular-biology-group/

 Our research
The Vascular Biology Group is a fast growing, interdisciplinary team, dedicated to understanding vascular physiology and pathophysiology.

We are interested in the cells that control the diameter of arteries, namely smooth muscle cells, which can contract and relax. In hypertension and atherosclerosis, hyper-contractility and restructuring of arterial smooth muscle cells leads to increased arterial tone and/or reduced blood flow. In the smooth muscle cells, several membrane proteins display altered function and expression, but without an understanding of how their membrane expression is controlled, development of new therapeutics to treat hypertension remains a distant dream. Our research will investigates trafficking mechanisms of specific membrane proteins, such as ion channels and receptors, which are dysregulated in vascular disease.

Your job
The Vascular Biology Group is investigating the cells that control the diameter of arteries, namely smooth muscle cells, which can contract and relax. Within these cells, is a cellular ‘road’ network termed the microtubule network, which moves proteins around the cell to ensure it contracts and relaxes properly. Smooth muscle cells are often dysfunctional in hypertension but very little is known about the microtubule network, particularly in hypertensive blood vessels. Your job is to investigate microtubule regulation of arterial tone and determine whether targeting microtubules can help treat hypertension.

Teamwork is extremely important within the Vascular Biology Group. Your will be expected to work closely with several PhD students on different areas of microtubule-related vascular biology. Your main task would be to identify if and how our novel microtubule findings contribute to the pathogenesis of hypertension.  Since we are a multidisciplinary team, it is important you are open and enjoy working with others on the same project.

Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:

Essential experience and skills:

  • You have a PhD in Physiology (preferably vascular background) or molecule biology (preferable involving microtubule research).
  • You are highly experienced in either cardiovascular physiology or microtubule biology.
  • You have an active interest to learn and discover. We need you to be highly experienced in either cardiovascular physiology or microtubule biology, therefore we you must show determination and work hard to strengthen and develop your skills in the area in which you do not have experience.
  • Proficient communication skills and ability to work in teams
  • Excellent English skills written and spoken

Desirable experience and skills:

  • It is necessary that you have experience and knowledge of working with animals and dissections to apply for this position.
  • It is necessary that your PhD included research within either vascular physiology or microtubule biology.
  • Desirable – experience in molecular biology techniques including (but not limited to): mass spectrometry, proximity ligation assays, immunostaining, live cell imaging, super-resolution microscopy.
  • Desirable – Knowledge of Western blotting, co-immunoprecipitation assays.

Place of employment
The place of employment is at Department of Biomedical Sciences, Panum Institute, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories, an integrative cardiovascular physiology environment and access to excellent imaging facilities.

Terms of employment
The employment as postdoc is a full time and fixed-term position for 2 years. Starting date is May 2020.

Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Currently, the monthly salary starts at 33,600 DKK/ approx. 4,480 Euro (April 2018-level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of June 28, 2013.

Questions
For further information please contact Thomas Jepps; tjepps@sund.ku.dk. Applications submitted by email will not be considered. Please follow the application procedure below.

Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).

Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore your application must include the following documents/attachments – all in PDF format:

1. Motivated letter of application (max. one page).

2. CV incl. education, work/research experience, language skills and other skills relevant for the position.

3. A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.

4. List of publications.

Application deadline:  31st March 2020, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

Interviews are expected to be held in week beginning 20th April 2020

Read the job description at the university homepage

Apply

University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of age, disability, gender, nationality, race, religion or sexual orientation. Appointment will be based on merit alone.

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Post expires on Tuesday March 31st, 2020

Postdoc in structural biology at Department of Drug Design and Pharmacology

Faculty of Health and Medical Sciences
University of Copenhagen

A 2-year postdoc position is available in the group of associate professor Osman Mirza at the Department of Drug Design and Pharmacology, University of Copenhagen.

The Mirza group works on structure-function studies of secondary active nutrient and drug transporters and recently also proteins that interact with these transporters. Basigin also referred to as CD147 or Extracellular matrix metalloproteinase inducer (EMMPRIN), is a type-1 membrane protein that interacts with many different macromolecules and is involved in several diseases such as cancer and malaria. Our focus is on understanding the structure of full-length human Basigin and its interactions with transport proteins. The postdoctoral fellow will drive the project, which will involve in vitro protein:protein interaction studies and structure elucidation using cryoEM, participate in the education and guidance of students, and write scientific publications.

Our group is part of the Protein and Peptides discipline at the department and has access to state-of-the art facilities for expression, purification and characterization of proteins. CryoEM studies will be performed in collaboration with collaborators at the iNANO (Aarhus University).   

Profile
We are looking for a highly motivated and enthusiastic scientist with the following competencies and experience:

Essential experience and skills:

  • You have a PhD in structural biology or related field
  • You are highly experienced in membrane protein production in eukaryotic cells and protein structure elucidation by cryoEM.
  • You have an active interest in protein:protein
  • Proficient communication skills and ability to work in teams
  • Excellent English skills written and spoken

Desirable experience and skills:

  • Chemical crosslinking of protein:protein complexes
  • Membrane proteins

Place of employment
The place of employment is at Department of Drug Design and Pharmacology, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories].

Terms of employment
The employment as postdoc is a full time and fixed-term position for 2 years. Starting date is 1 May 2020 or soon hereafter.

Salary, pension and terms of employment will be in accordance with the agreement between the Danish Ministry of Finance and AC (Danish Confederation of Professional Associations). Currently, the monthly salary starts at 34,360 DKK/ approx. 4,590 Euro (October 2019-level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of 11 December 2019.

Questions
For further information please contact Osman Mirza om@sund.ku.dk; www.sund.ku.dk

Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).

Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore, your application must include the following documents/attachments – all in PDF format:

  1. Motivated letter of application (max. one page).
  2. CV incl. education, work/research experience, language skills and other skills relevant for the position.
  3. A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
  4. List of publications.

Application deadline:  12 March 2020, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

Interviews are expected to be held are expected to be held within a month after the application deadline.

University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of age, disability, gender, nationality, race, religion or sexual orientation. Appointment will be based on merit alone.

Read the job description at the university homepage

Login and apply


Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Post expires on Thursday March 12th, 2020

PhD fellowship in protein biophysics at the Department of Drug Design and Pharmacology

Faculty of Health and Medical SciencesUniversity of Copenhagen

We are offering a three-year PhD fellowship in protein biophysics commencing 1 June 2020 or as soon as possible hereafter in the Galvagnion group “Protein-membrane interactions in health and disease”.

Our group and researchOur research aims at understanding the role of dysfunctions in lipid homeostasis in the emergence of neurodegenerative diseases including Alzheimer’s and Parkinson’s Diseases. Our approach consists in identifying, using biological models, lipid changes associated with these diseases and/or their risk factors and in using biophysical methods to provide at the molecular level the mechanism by which these lipid changes can influence functional protein-protein and protein-membrane interactions as well as protein aggregation. Our interdisciplinary research involves an international collaborative network including neuroscientists, stem cell biologists, biochemists, protein biophysicists and lipid chemists.

More information on our research can be found here:

Project descriptionParkinson’s Disease (PD) is the second most common neurodegenerative disease and is characterized by the loss of dopaminergic neurons and the presence of protein deposits in the brain of patients. These deposits are mainly composed of the protein α-synuclein but can also contain other molecules such as lipids. Moreover, increasing evidence points towards a link between mutations in genes encoding proteins involved in lipid homeostasis, changes in lipid levels and PD / α-synuclein pathology. However, the mechanism by which these PD associated genetic mutations may lead to the formation of α-synuclein toxic aggregates in the cells and in vivo remains to be addressed.

The advertised research project aims at studying how genetic mutations associated with risk factors for PD can lead to the loss of function of proteins involved in lipid metabolism and to the formation of toxic aggregates by α-synuclein in vitro. In particular, proteins involved in lipid metabolism and their PD associated variants will be produced in E.Coli and yeast cells. The influence of PD related genetic mutations on the stability of these proteins, their interaction with α-synuclein and their ability to modulate α-synuclein aggregation will be investigated at the molecular level using a range of biophysical methods including circular dichroism, fluorescence spectroscopy, calorimetry and microscopy.

We are looking for a highly motivated and independent PhD student with an expertise in molecular biology, protein expression and purification and protein biophysics.

Principal supervisor:Assoc. Prof. Céline GalvagnionDepartment of Drug Design and PharmacologyE-mail: celine.galvagnion@sund.ku.dkWeb: drug.ku.dkDirect Phone: +45 3533 7828.Start:                 1 June 2020Duration:          3 years as a PhD student

Job descriptionYour key tasks as a PhD student at SUND are:

  • Carry through an independent research project under supervision
  • Complete PhD courses or other equivalent education corresponding to approx. 30 ECTS points
  • Participate in active research environments including a stay at another research team
  • Obtain experience with teaching or other types of dissemination related to your PhD project
  • Teach and disseminate your knowledge
  • Write a PhD thesis on the grounds of your project

Key criteria for the assessment of applicantsApplicants must have qualifications corresponding to a master’s degree related to the subject area of the project e.g. molecular biology and protein biophysics

Other important criteria are:

  • The grade point average achieved
  • Professional qualifications relevant to the PhD project
  • Previous publications
  • Relevant work experience
  • Other professional activities
  • Curious mind-set with a strong interest in neuroscience, lipid metabolism, protein folding, protein-protein and protein-membrane interaction, protein aggregation
  • Language skills

Place of employmentThe place of employment is at the Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories, a protein production and purification facility and protein biophysics instruments.

Terms of employmentThe employment as PhD fellow is full time and for 3 years.

It is conditioned upon the applicant’s success­ful enrolment as a PhD student at the Graduate School at the Faculty of Health and Medical Sciences, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant.

The PhD study must be completed in accordance with The Ministerial Order on the PhD programme (2013) and the Faculty’s rules on achieving the degree. Salary, pension and terms of employment are in accordance with the agree­ment between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary begins around 27,360 DKK /approx. 3,660 EUR (October 2019-level) plus pension.

QuestionsFor specific information about the PhD fellowship, please contact the principal supervisor.

General information about PhD study at the Faculty of Health and Medical Sciences is available at the Graduate School’s website: https://healthsciences.ku.dk/phd/guidelines/

Application procedure

Your application must be submitted electronically by clicking ‘Apply now’ below. The application must include the following documents in PDF format: 

  • Motivated letter of application (max. one page)
  • CV incl. education, experience, language skills and other skills relevant for the position
  • Master of Science diploma and transcript of records. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor will do
  • Publication list (if possible)
  • Application deadline: 12 March 2020, 23.59pm CET

    We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

    The further processAfter the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.

    The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement.

    Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

    You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/

    The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

    Interviews are expected to be held between via Skype between 2 April 2020 and 8 April 2020 and in person at the Department of Drug Design and Pharmacology between 20 April 2020 and 28 April 2020.

    The Faculty of Health and Medical Sciences comprises approximately 7800 students, 1550 PhD students and 4400 employees. The Faculty advances the field of health sciences through its core activities: research, teaching, knowledge sharing and communication. With basic research fields ranging from molecular studies to studies of society, the Faculty contributes to a healthy future through its graduates, research findings and inventions benefitting patients and the community. The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position. 

    APPLY NOW

    Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

    Deadline: 12 March 2020
    Unit: Faculty of Health and Medical Sciences
    Campus: Department of Drug Design and Pharmacology
    Email: celine.galvagnion@sund.ku.dk
    Phone:
    Read the job description and apply online

    Post expires on Thursday March 12th, 2020

    Postdoctoral studies in HIV latency and chromatin

    Karolinska Institutet, Department of Biosciences and Nutrition, Svensson (PSV)

    The Department of Biosciences and Nutrition performs research and education in several areas of medical science including bioorganic chemistry, molecular endocrinology, cancer biology, functional genomics, systems biology, epigenetics, structural biochemistry, cellular virology, and nutrition. It offers an excellent international research and working environment, including around 300 scientists, students, administrative and technical personnel. The Department resides in the new biomedical research building Neo, aimed at being a creative and open environment that enables meetings, synergies, and exploration of areas of mutual interest across disciplines.

    Division
    The research group of Peter Svensson at the department of Biosciences and Nutrition is looking for a Postdoctoral fellow in the field of HIV, https://ki.se/en/bionut/mechanisms-behind-hiv-1-latency-and-rebound-peter-svenssons-group

    The lab studies interactions between viruses and the host cell. By understanding how these interact we hope to gain insights into both cellular processes and the viral replicative cycle. Our main emphasis lies on how retroviruses such as HIV-1 and HTLV-1 make use of the host chromatin and transcription machinery. Specifically, our research group focuses on revealing molecular mechanisms behind epigenetic state reversal of the HIV-1 provirus.

    Researchers in our group investigate the establishment, maintenance and transition between chromatin states of the HIV-1 provirus. The circuitry of HIV-1 latency is modeled and tested in cell lines, as well as primary cells from both HIV- and HIV+ donors. In the lab we view epigenetic state reversal of HIV-1 as a general model to understand the activation and silencing of other loci important for e.g. development and cancer.  

    Duties
    We are looking for a highly motivated and qualified Postdoctoral fellow, which will be financed by a scholarship. The postdoc will carry out a research project to delineate how the host machinery is engaged in the latency reversal of HIV-1 and HTLV-1. This includes the refinement and use of novel single-cell methodology to identify determinants of the proviral latency reversal.

    Qualifications
    The ideal candidate holds a PhD in the field of epigenetics or virology and has previous experience handling human cells. Experience with HIV-1 is a merit, knowledge and practical experience with chromatin and microscopy is advantageous. The project demands ability to plan, develop and use advanced molecular biology to study chromatin and transcription. You are expected to be able to work independently within a team environment.  Proficiency in English is required and a proven track record of scientific writing (e.g. from published manuscripts) is expected.

    Entry requirements
    Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
    A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
    To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate.

    The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

    Type of scholarship
    The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

    Application process
    An application must contain the following documents in English or Swedish:

    • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
    • A complete list of publications
    • A summary of current work (no more than one page)

    The application is to be submitted on the Varbi recruitment system.

    Reference number2-384/2020
    ContactThomas Tinglöv, Head of Adminsitration, +46- 8-524 835 49Peter Svensson, Researcher and Group Leader, +46-730358315
    Union representativeHenry Wölling, SEKO, +46-8-524 840 80Birgitta Lindqvist, OFR, +46-73-209 83 12
    Last application date22.Mar.2020 11:59 PM CET

    Read the job description at the university homepage

    Login and apply

    Post expires on Sunday March 22nd, 2020

    Doctoral (PhD) student position in HIV-1 latency and chromatin:

    Karolinska Institutet, Department of Biosciences and Nutrition, Svensson (PSV)

    The Department of Biosciences and Nutrition performs research and education in several areas of medical science including bioorganic chemistry, molecular endocrinology, cancer biology, functional genomics, systems biology, epigenetics, structural biochemistry, cellular virology, and nutrition. It offers an excellent international research and working environment, including around 300 scientists, students, administrative and technical personnel. The Department resides in the new biomedical research building Neo, aimed at being a creative and open environment that enables meetings, synergies, and exploration of areas of mutual interest across disciplines.

    Do you want to contribute to top quality medical research?

    To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

    The research group
    The research group of Peter Svensson at the department of Biosciences and Nutrition is looking for a Phd student in the field of HIV. The lab studies interactions between viruses and the host cell. By understanding how these interact we hope to gain insights into both cellular processes and the viral replicative cycle. Upon infection of HIV-1, the causative agent for AIDS, the virus integrates in the genome of T-cells. There the provirus may stay latent in chromatin for years before it activates and re-spreads the infection. HIV-1 latency remains the main obstacle in the treatment of HIV-positive individuals.

    Researchers in our group investigate the establishment, maintenance and transition between chromatin states of the HIV-1 provirus. The circuitry of HIV-1 latency is modeled and tested in cell lines, as well as primary cells from both HIV- and HIV+ donors. In the lab we also view epigenetic state reversal of HIV-1 as a general model to understand the activation and silencing of other genetic loci important for e.g. development and cancer.  

    The doctoral student project and the duties of the doctoral student
    The overall aim of this PhD project is to identify and characterize mechanisms that control the latent HIV provirus. The student will study chromatin and transcription in a range of cell systems, from established cell lines, via in vitro infected primary cells to material directly isolated from HIV patients. A range of innovative method will be used, including those based on flow cytometry, microscopy and single cell chromatin characterization.

    What do we offer?
    A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

    Eligibility requirements for doctoral education
    In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

    It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

    A) General eligibility requirement
    You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

    1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree) or
    2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
    3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

    Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

    *If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

    B) Specific eligibility requirement

    You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

    – Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

    Follow the instructions on the web page English language requirements for doctoral education.

    Verification of your documentsKarolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

    Skills and personal qualities
    We are seeking a highly motivated, enthusiastic and ambitious student with strong interest in chromatin and HIV. Candidates must be able to work within a team environment but retain independence to explore their own hypotheses and results and drive their own projects. The applicant must be fluent in English, with excellent communication and advanced writing skills. The PhD student is expected to take a strong lead in project management, data generation, as well as analyses and interpretation. Prior experience with epigenetics, virology, microscopy as well as molecular biology and analytical methods is considered an advantage for this project. Authorship on research articles is highly meriting, as is previous training in research laboratories.

    Terms and conditions
    The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

    –[Video about the Karolinska Institutet, how we all work towards “a better health for all”] —

    — [Video about a workingday in Flemingsberg, delete if the location is in Solna] —

    Application process
    Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions.

    Your application should contain the following documents:

    – A personal letter and a curriculum vitae (Swedish or English)
    – Degree projects and previous publications, if any (Swedish or English)
    – Any other documentation showing the desirable skills and personal qualities described above (Swedish or English)
    – Documents certifying your general eligibility (see A above)
    – Documents certifying your specific eligibility (see B above)

    Selection
    A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

    Karolinska Institutet uses the following bases of assessment:

    – Documented subject knowledge of relevance to the area of research
    – Analytical skill
    – Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

     All applicants will be informed when the recruitment is completed.

    https://ki.se/en/bionut/mechanisms-behind-hiv-1-latency-and-rebound-peter-svenssons-group

    Want to make a difference? Join us and contribute to better health for all

    Type of employmentPhD placement
    Contract typeFull time
    Reference number2-383/2020
    ContactThomas Tinglöv, Head of Administration, +46-8-524 835 49Peter Svensson, Researcher and Group Leader, +46-730358315
    Union representativeHenry Wölling, SEKO, +46-8-524 840 80Birgitta Lindqvist, OFR, +46-73-209 83 12
    Last application date22.Mar.2020 11:59 PM CET

    Read the job description at the university homepage

    Login and apply

    Post expires on Sunday March 22nd, 2020

    Post doc in the cognitive neuroscience of aging

    Karolinska Institutet, Department of NVS

    Do you want to contribute to top quality medical research?

    At Aging Research Center (ARC) we conduct research with focus on older people and aging. ARC, within the Department of NVS is a multidisciplinary academic environment, representing psychology, sociology, and various branches of medicine (e.g., neurology, epidemiology, psychiatry, geriatrics).  
    Major research foci in the psychology section at ARC concern: (a) sources of individual differences in cognitive functioning among older adults; (b) the neural underpinnings of age-related differences in cognition, as assessed using structural and functional MRI; (c) PET research on the role of dopamine functions in cognitive aging; and (d) intervention research examining cognitive and brain plasticity in old age.
    ARC is now opening a post doc position for two years with planned start in March 2020.

    COBRA
    The present post is based on the Cognition, Brain, and Aging (COBRA) project, in which data collection takes place at Umeå University. COBRA examines the relationship of the neurotransmitter dopamine (DA) and other brain parameters (i.e., grey- and white matter volumes, white-matter microstructure, functional activation patterns during rest and task performance, perfusion) to cognitive performance and change in aging, with a chief focus on longitudinal trajectories of DA availability and how those map onto corresponding cognitive paths.

    Your mission

    A major task for candidate will be to contribute to the research activities within COBRA, conceptually as well as methodologically. In addition, there are possibilities to initiate individual research projects, based on the candidate´s interests.

    Your profile

    We are  looking for you who have a strong track record in terms of publications. Research experience regarding different brain imaging modalities is required. In particular, documented skills in integrating MRI data (e.g., functional connectivity, white-matter microstructure) and PET data (i.e., dopamine binding) as they relate to cognition weigh heavily in the recruitment process.
    A person is eligible to be appointed as a post doc if he or she has been awarded a doctoral degree or has achieved the corresponding scientific competence. We stress research expertise when assessing applicants. We  conduct research in an multicultural environment and collaborative skills are important as well as good knowledge in English.

    What do we offer?

    A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.
    Location: Solna, Stockholm. https://ki-su-arc.se/

    Application

    An employment application must contain the following documents in English or Swedish:

    • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
    • A complete list of publications
    • A summary of current work (no more than one page)

    Welcome to apply at the latest March 25, 2020.
    The application is to be submitted through the Varbi recruitment system.

    Want to make a difference? Join us and contribute to better health for all!

    Type of employmentTemporary position longer than 6 months
    Contract typeFull time
    First day of employmentAccording to agreement
    SalaryMonthly salary
    Number of positions1
    Working hoursFull time
    CitySolna
    CountyStockholms län
    CountrySweden
    Reference number2-6073/2019
    ContactLars Bäckman, Professor, lars.backman.1@ki.seJohan Fritzell, Head of division, Professor, johan.fritzell@ki.seMaria Axelsson, HR officer, 08-524 882 96 HR@nvs.ki.se
    Union representativeBiborka Bereczky Veress, SACO, 46 70-173 85 75Carina Eklund, OFR, 08-585 826 65Henry Wölling, SEKO, 08-524 840 80
    Last application date25.Mar.2020 11:59 PM CET

    Read the job description at the university homepage

    Login and apply

    Post expires on Wednesday March 25th, 2020