Tag Archives: Karolinska

Postdoctoral position: DNA damage as a driver of adipocyte senescence (3)

Do you want to contribute to top quality medical research?

The Strategic Research Programme in Diabetes (SRP Diabetes) at Karolinska Institutet is funding a prestigious fellowship programme for postdoctoral research fellows. The Programme is focused on research in diabetes and its comorbidities. With this postdoctoral programme SRP Diabetes aims to support the next generation of exceptional young scientists within the diabetes area, including both experimental and clinical research. As part of this programme, we are now looking to recruit 4 outstanding postdoctoral research fellows. Full details on each project and contact information to the PIs can be found at: http://ki.se/en/srp-diabetes/postdoctoral-fellowships

Based at Karolinska Institutet, fellows will undertake a cutting-edge research project in a competitive lab and be part of the SRP Diabetes dynamic research environment where several events will be held throughout the year such as high-profile lectures, symposia, internal retreat, etc. which the fellows will attend

The fellowships are fully funded, and salary is provided for a 2-year period. It is our intention that the positions will start in the autumn of 2023, though some flexibility with the start date might be possible.

Research Project 3

Investigating DNA damage as a driver of adipocyte senescence and inflammation in obese, hyperinsulinemic individuals

Senescent cells, which can release factors that cause inflammation and dysfunction, increase in adipose tissue and associate with obesity and hyperinsulinemia. The proposed project will determine whether oxidative stress and DNA damage in human adipocytes drives adipocyte senescence, and the associated pro-inflammatory secretory profile. A small molecule approach to attenuate adipocyte DNA damage and reverse adipocyte senescence will be investigated.

Key responsibilities of the selected applicant:

Plan, manage and conduct an agreed academic research project and associated activities.

  • Test hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate.
  • Develop research questions, analyse detailed and complex qualitative and/or quantitative data from a variety of sources, and contribute original ideas for new research projects.
  • Coordinate multiple aspects of work to deliver novel research data in accordance with established timelines set between you and the Principal Investigator.
  • Adapt existing and develop new scientific techniques and experimental protocols to support research.
  • Write research articles at an international level for peer-reviewed journals, book chapters, and reviews.
  • Formally present your research and represent the research group at internal, national and international conferences and meetings, either with other members of the team or alone.
  • Informally present your research to the group at established meetings.
  • Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

Selection Criteria

Essential 

  • A PhD in a medical/biological subject (latest completion date 2023).
  • Demonstrated expertise in oxidative stress, mitochondria and DNA damage.
  • The ability to manage your own academic research and associated activities.
  • A strong CV, having published in high impact journals and presented at international meetings.
  • Ability to contribute ideas for new research projects and research income generation.
  • Ability to work with meticulous attention to detail.
  • An enthusiastic interest in diabetes research.
  • Evidence of excellent interpersonal skills and leadership, with the ability to communicate research ideas and results in a clear and logical way and the ability to confidently and effectively interact with colleagues and the broader research community.
  • Strong verbal and written communication skills in English.
  • A conscientious and enthusiastic working approach.
  • Excellent planning, organizational and problem-solving skills.

Advantageous

  • Experimental and theoretical knowledge of adipose tissue biology
  • Microscopy (including confocal) and immunocytochemistry

Each Fellowship is for two years. We will prioritize applicants who have the opportunity to complete the project and be employed for two years. Preference should be given to those who were awarded a PhD or attained equivalent research competence no more than three years prior to the expiry of the application period for the position as postdoc.

Location: Solna

How to apply

If you consider that you meet the selection criteria, click on the Login and apply button on this page and follow the on-screen instructions to register as a user. You will then be required to provide information in a number of screens with your application details, relating to your skills and experience. When prompted, please provide details of three references. You will also be required to upload a CV and Personal Letter which explains how you meet the selection criteria for the position. The Personal Letter (maximum two pages) should explain your relevant experience which may have been gained in employment, education, or you may have taken time away from these activities as illness, military service, work for labour unions or student organisations, parental leave or similar circumstances. Your application will be judged in part on the basis of how you demonstrate that you meet the selection criteria outlined above and we are happy to consider evidence of transferable skills or experience which you may have gained outside the context of paid employment or education.

Please save all uploaded documents to show your name and the document type.

The application is to be submitted through the Varbi recruitment system.

The closing date for applications is midnight CEST on Sunday 30th April, 2023.

Working at Karolinska Institutet

For further information about working at Karolinska Institutet, rules for visa/residence permit, insurance and accommodation please see: International staff

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-04-30 at 23:59
Unit: at one of KI’s departments

Read the job description at the university homepage or apply.

Post expires on Sunday April 30th, 2023

Postdoctoral position: Insulin nanotechnology (4)

Do you want to contribute to top quality medical research?

The Strategic Research Programme in Diabetes (SRP Diabetes) at Karolinska Institutet is funding a prestigious fellowship programme for postdoctoral research fellows. The Programme is focused on research in diabetes and its comorbidities. With this postdoctoral programme SRP Diabetes aims to support the next generation of exceptional young scientists within the diabetes area, including both experimental and clinical research. As part of this programme, we are now looking to recruit 4 outstanding postdoctoral research fellows. Full details on each project and contact information to the PIs can be found at: http://ki.se/en/srp-diabetes/postdoctoral-fellowships

Based at Karolinska Institutet, fellows will undertake a cutting-edge research project in a competitive lab and be part of the SRP Diabetes dynamic research environment where several events will be held throughout the year such as high-profile lectures, symposia, internal retreat, etc. which the fellows will attend

The fellowships are fully funded, and salary is provided for a 2-year period. It is our intention that the positions will start in the autumn of 2023, though some flexibility with the start date might be possible.

Research Project 4

Mapping the biodistribution of multivalent insulin variants in zebrafish and in mice

At the Teixeira lab (Ana Teixeira-group), we have developed DNA nanotechnology-based  approaches to map and target membrane protein nanodomains (e.g. Ambrosetti et al, Nat Nanotechnology, 2021; Fang et al, ACS Nano, 2021; Verheyen, Fang et al, Nucleic Acids Research, 2020; Shaw, Lundin, et al, Nat Methods 2014). In this project, the postdoctoral research fellow will investigate the nanoscale spatial organization of insulin receptors in different tissues. This information will be used to develop multivalent insulin variants using DNA- and protein-based self-assembly. The biodistribution and tissue specific effects of different multivalent insulin variants will be mapped in wild type and diabetes models in zebrafish and mice. This work aims to form the basis for the future development of insulin variants with tailored tissue targeting patterns.

Key responsibilities of the selected applicant:

  • Plan, manage and conduct an agreed academic research project and associated activities.
  • Test hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate.
  • Develop research questions, analyse detailed and complex qualitative and/or quantitative data from a variety of sources, and contribute original ideas for new research projects.
  • Coordinate multiple aspects of work to deliver novel research data in accordance with established timelines set between you and the Principal Investigator.
  • Adapt existing and develop new scientific techniques and experimental protocols to support research.
  • Regularly write research articles at an international level for peer-reviewed journals, book chapters, and reviews.
  • Formally present your research and represent the research group at internal, national and international conferences and meetings, either with other members of the team or alone.
  • Informally present your research to the group at established meetings.
  • Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

Selection Criteria

Essential

  • A PhD in a medical/biological subject (to be completed in 2023).
  • The ability to manage your own academic research and associated activities.
  • A strong CV, having published in high impact journals and presented at international meetings.
  • Ability to contribute ideas for new research projects and research income generation.
  • Ability to work with meticulous attention to detail.
  • An enthusiastic interest in diabetes research.
  • Evidence of excellent interpersonal skills and leadership, with the ability to communicate research ideas and results in a clear and logical way and the ability to confidently and effectively interact with colleagues and the broader research community.
  • Strong verbal and written communication skills in English.
  • A conscientious and enthusiastic working approach.
  • Excellent planning, organizational and problem-solving skills.

In addition, experience in one or several of the following is valued:

  • DNA nanotechnology
  • Surface Plasmon Resonance spectroscopy
  • Super-resolution microscopy
  • Single cell biology
  • Animal models

Each Fellowship is for two years. We will prioritize applicants who have the opportunity to complete the project and be employed for two years. Preference should be given to those who were awarded a PhD or attained equivalent research competence no more than three years prior to the expiry of the application period for the position as postdoc.


Location: Solna

How to apply

If you consider that you meet the selection criteria, click on the Login and apply button on this page and follow the on-screen instructions to register as a user. You will then be required to provide information in a number of screens with your application details, relating to your skills and experience. When prompted, please provide details of three references. You will also be required to upload a CV and Personal Letter which explains how you meet the selection criteria for the position. The Personal Letter (maximum two pages) should explain your relevant experience which may have been gained in employment, education, or you may have taken time away from these activities as illness, military service, work for labour unions or student organisations, parental leave or similar circumstances. Your application will be judged in part on the basis of how you demonstrate that you meet the selection criteria outlined above and we are happy to consider evidence of transferable skills or experience which you may have gained outside the context of paid employment or education.

Please save all uploaded documents to show your name and the document type.

The application is to be submitted through the Varbi recruitment system.

The closing date for applications is midnight CEST on Sunday 30th April, 2023.

Working at Karolinska Institutet 

For further information about working at Karolinska Institutet, rules for visa/residence permit, insurance and accommodation please see: International staff

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-04-30 at 23:59
Unit: at one of KI’s departments

Read the job description at the university homepage or apply.

Post expires on Sunday April 30th, 2023

Postdoctoral researcher in motor control neuroscience

Do you want to contribute to top quality medical research?

A postdoctoral position on sensorimotor integration and neural control of movement is available at the Department of Neuroscience. The project will have a particular focus on the integration of sensory feedback on movements in mice. This is a collaborative project between the labs of Abdel El Manira, Francois Lallemend and Laurence Picton and will involve multiple advanced techniques. The selected candidate will investigate the functional properties and connectivity of proprioceptive neurons and will explore proprioceptive feedback pathways in the brainstem and spinal cord. The project will involve the use of viral tracing, electrophysiology, optogenetics and behavioral analysis.

The Department of Neuroscience at KI offers a multidisciplinary and diverse research environment with a strong community and a number of leading labs in motor control neuroscience.

Your mission

In this postdoctoral role you will study proprioceptive feedback pathways for motor control. The applicant should have experience working with transgenic mice, virus injections and surgeries and have a strong interest in understanding sensory feedback for mammalian motor control.

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

We are seeking applicants with a PhD and strong background in motor control neuroscience. The ideal candidate should have experience in the following techniques:
•    Experimental work with transgenic mouse lines
•    Virus injections
•    Stereotaxic surgery
•    Histology
•    Mouse behavior
•    Electrophysiology

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna
Neuroscience is one of the strategic research areas at Karolinska Institutet. There many leading labs at the Department of Neuroscience focusing on brain circuit organization and function using a range of advanced techniques. The Department of Neuroscience offers a vibrant environment with an open and collaborative atmosphere.

https://ki.se/en/neuro/lallemend-lab
https://www.elmaniralab.org

Application

The application is to be submitted through the Varbi recruitment system. In this recruitment, you will apply with your CV without a personal letter. Instead, you will answer some questions about why you are applying for the job in the application form.

This is a fixed-term position for 2 years with the possibility of extension for 1 year.

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

Welcome to apply at the latest 13th of April 2023!

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-04-13 at 23:59
Unit: El Manira

Read the job description at the university homepage or apply.

Post expires on Thursday April 13th, 2023

Postdoctoral studies in exosome-based cancer therapy and liquid biopsy development (scholarship)

Do you want to contribute to top quality medical research?

Our research efforts in the EL Andaloussi´s lab focus on one of the greatest challenges facing modern therapeutics; delivery of macromolecules to target cells in vivo. Despite the unprecedented knowledge of diseases and their mechanisms due to advances in biomedical sciences; many promising therapeutic approaches are still clinically unavailable. This is simply because there is no efficient means of delivering these therapeutics to the right tissue with the right dose. Our research performance involves developing novel and innovative drug delivery technologies that can carry therapies to the target tissues safely and efficiently. In this connection, we engineer exosomes with enhanced delivery and targeting capacities and screen our wide array of exosome designs in disease-relevant cellular and animal models. In parallel, exosomes can also be used for diagnostic purposes. Tumor derived exosomes can be found in all body fluids and can act as a fingerprint, carrying genomic and proteomic information of the cancer. Liquid biopsy is an expanding research field with the hope to improve cancer monitoring and improve implementation of personalized cancer therapies. Even though the field has been largely dominated by circulating tumor cells (CTCs) and DNA (ctDNA), exosomes may have the ability to further improve early cancer detection as exosomes are believed to be secreted at an earlier time point of the cancer development. Thus, our research platform offers a unique opportunity for discovering and developing advanced exosome-based therapeutics and diagnostic tools.  

We are now looking for a Postdoctoral Research fellow for a scholarship.


Your mission

As a Postdoctoral Research fellow, you will be involved in the development of bioengineered extracellular vesicles (EVs) as novel cancer therapies and development of improved strategies for enrichment of tumor derived EVs as an improved liquid biopsy platform in cancer.

Most of the research will initially be conducted utilizing cell lines and animal models before the methods are applied to patient material. The duties will involve developing stable cell lines for production of EVs engineered to harbor reporter proteins, with or without a therapeutic/targeting domain. The stable cells will be used both for screening of suitable cell source for therapeutic applications of EVs and for labeling of tumor derived EVs used for optimization of isolation techniques from complex media such as plasma. Next, the therapeutically engineered EVs will be loaded with anti-tumoral drugs and assessed in vitro and in vivo. Following successful isolation protocol, the labeled tumor derived EVs (and later patient derived EVs) will be sequenced and undergo proteomic analysis, which will be compared to ctDNA/CTCs. 

Your profile

The applicant should have a solid background in molecular and tumor biology or biotechnology. The position requires practical lab experience in the following areas; RNA-sequencing and experience with molecular cloning and extensive knowledge regarding cell culture work including generation of stable cell clones for protein expression proteomics. Secondly, experience with proteomics and flow cytometric analysis of protein expression are wanted. The ideal candidate would furthermore have experience within the EV or virus field. FELASA level animal license and experience from experimental work in rodents is meritorious.

In addition, excellent proficiency in both spoken and written English is important. We are looking for an energetic and passionate person who fits in, and actively contributes to our team.

Entry requirements

The eligible candidate for the Postdoctoral Researcher scholarship should hold a PhD degree dated no more than 7 years before the last date of employment as postdoc. The term can be extended under special circumstances.

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Location: Flemingsberg

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.

Welcome to apply at the latest 10 April. 

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-04-10 at 23:59
Unit: Department of Laboratory Medicine

Read the job description at the university homepage or apply.

Post expires on Monday April 10th, 2023

Postdoctoral studies in Inflammation and cancer (scholarship)

Do you want to contribute to top quality medical research?

The research team of Assistant Professor Dr. Sylvain Peuget investigates how the bacterial microbiota participates in cancer initiation and progression. Metagenomics studies have highlighted dysregulation of the microbiota composition in cancer patients compared to healthy individuals. However, how bacteria influence cancer is still poorly understood. More specifically, we are interested in the molecular mechanisms which link bacterial dysbiosis, inflammation and alterations of the tumor suppressor p53 pathway, and ultimately cancer.

Division

The Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet conducts research and teaching within immunology, infection biology, cell biology and cancer. MTC have about 40 research groups and our key words are multidisciplinary, bridging, national and international collaborations

Duties

P53 is the main tumor suppressor gene in humans, and is inactivated in virtually all cancer, either by mutation or by other mechanisms, across all tumor types. Interestingly, the splicing factor ZMAT3 has been shown to be critical for p53 tumor suppressive function. Our previous work and preliminary data suggest that ZMAT3 plays an important role during inflammation. The project aims at understanding the role of ZMAT3 in inflammation and innate immune response, both in vivo and in a novel mouse model.

The successful candidate will:

  • Establish and characterize a new conditional ZMAT3 KO mouse model
  • Investigate its response in a setting of inflammatory-driven carcinogenesis
  • Decipher the molecular mechanisms linking ZMAT3 and inflammation in vivo

Additionally, the candidate is expected to contribute to the lab routine duties of the group, will participates in group meetings and journal clubs, and will have the opportunity to attend international conferences on the topic. This project will be performed in close collaboration with Prof. Klas Wiman’s lab, discoverer of the gene ZMAT3, and Ass. Prof. Marie-Stéphanie Aschtgen, expert in infection biology, both at Karolinska Institutet.

Entry requirements

We are looking for a highly motivated, curious and creative candidate, with a background in Cancer biology or Immunology.

  • A strong experience in mouse models is required, including with Cre recombinase system, breeding and management of a small colony of animals. Previous experience with AOM-DSS model is a plus.
  • Hands-on laboratory experience with mammalian cell culture, flow cytometry, and basic techniques in biochemistry (western blots, RT-qPCR) is required.
  • Knowledge on the p53 and/or NFkB pathway, as well as experience with RNAseq data analysis are highly valued.
  • Successful candidates should be self-driven and passionate about the research themes developed in the lab, have strong organizational skills, and be willing to be part of the lab team-work.

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.

A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent. To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Location: Solna

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-04-12 at 23:59
Unit: Selivanova

Read the job description at the university homepage or apply.

Post expires on Wednesday April 12th, 2023

Postdoctoral position: Integrating transcriptomics and chemical biology for induction of ß-cells (1)

Do you want to contribute to top quality medical research?

The Strategic Research Programme in Diabetes (SRP Diabetes) at Karolinska Institutet is funding a prestigious fellowship programme for postdoctoral research fellows. The Programme is focused on research in diabetes and its comorbidities. With this postdoctoral programme SRP Diabetes aims to support the next generation of exceptional young scientists within the diabetes area, including both experimental and clinical research. As part of this programme, we are now looking to recruit 4 outstanding postdoctoral research fellows. Full details on each project and contact information to the PIs can be found at: http://ki.se/en/srp-diabetes/postdoctoral-fellowships

Based at Karolinska Institutet, fellows will undertake a cutting-edge research project in a competitive lab and be part of the SRP Diabetes dynamic research environment where several events will be held throughout the year such as high-profile lectures, symposia, internal retreat, etc. which the fellows will attend

The fellowships are fully funded, and salary is provided for a 2-year period. It is our intention that the positions will start in the autumn of 2023, though some flexibility with the start date might be possible.

Research Project 1

Integrating transcriptomics and chemical biology for induction of β-cells

Diabetes features a reduction in the number of functional β-cells, a key pathologic event that causes or exacerbates the dysregulation of blood glucose levels. Regenerating insulin-producing β-cells might prove a better treatment for diabetes, which is at present controlled but not reversed by insulin injections. Therefore, the main interest in the lab of Olov Andersson is to determine how small molecules and cellular mechanisms can promote regeneration of insulin-producing beta-cells and improve metabolic control, as potential curative approaches for diabetes. The successful applicant will use chemical-genetic screening techniques in zebrafish to identify compounds, genes and signalling pathways that can promote β-cell regeneration.

Signaling between different pancreatic cell types will be identified using bioinformatics tools, and the identified pathways will be perturbed (using genetics or small molecules know to target the pathways) and assessed for involvement in progenitor maintenance or differentiation of progenitors to β-cells in zebrafish.

We will lineage-trace specific progenitor populations, as well as isolate the progenitor cells and their differentiated descendants to delineate the mechanisms of β-cell regeneration by single-cell RNA-seq. We will then perturb candidate pathways in human organoids derived from ductal cells to determine whether their effects on β-cell neogenesis are conserved across species.

The present project will span from chemical biology to genetics in zebrafish, as well as translational studies using human organoids. The studies will include assessing beta-cell neogenesis, proliferation and transdifferentiation, and how such cellular changes may affect glycemia.

The zebrafish are amenable to efficient transgenesis and high-resolution imaging. We will make use of these properties to generate transgenic, knock-in and mutant zebrafish for single-cell analysis of phenotypes and lineage tracing.

Visit the lab’s website for examples of how the research can be conducted:
Olov Anderssons-group

Key responsibilities of the selected applicant:

  • Plan, manage and conduct an agreed academic research project and associated activities.
  • Test hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate.
  • Develop research questions, analyse detailed and complex qualitative and/or quantitative data from a variety of sources, and contribute original ideas for new research projects.
  • Coordinate multiple aspects of work to deliver novel research data in accordance with established timelines set between you and the Principal Investigator.
  • Adapt existing and develop new scientific techniques and experimental protocols to support research.
  • Write research articles and reviews for peer-reviewed journals.
  • Formally present your research and represent the research group at internal, national and international conferences and meetings, either with other members of the team or alone.
  • Informally present your research to the group at established meetings.
  • Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

Selection Criteria

Essential 

  • A PhD in a medical/biological subject (to be completed in 2023).
  • Experience in molecular, cellular and biochemical techniques, e.g. cloning, qPCR, Western blot and immunohistochemistry.
  • Experience in bioinformatics, drug screening, organoid cultures, or the zebrafish model.
  • Published in established journals and presented at meetings.
  • Ability to work with meticulous attention to detail.
  • An enthusiastic interest in diabetes research.
  • The ability to manage your own academic research and associated activities.
  • Strong verbal and written communication skills in English.

Each Fellowship is for two years. We will prioritize applicants who have the opportunity to complete the project and be employed for two years. Preference should be given to those who were awarded a PhD or attained equivalent research competence no more than three years prior to the expiry of the application period for the position as postdoc.

Location: Solna

How to apply

If you consider that you meet the selection criteria, click on the Login and apply button on this page and follow the on-screen instructions to register as a user. You will then be required to provide information in a number of screens with your application details, relating to your skills and experience. When prompted, please provide details of three references. You will also be required to upload a CV and Personal Letter which explains how you meet the selection criteria for the position. The Personal Letter (maximum two pages) should explain your relevant experience which may have been gained in employment, education, or you may have taken time away from these activities as illness, military service, work for labour unions or student organisations, parental leave or similar circumstances. Your application will be judged in part on the basis of how you demonstrate that you meet the selection criteria outlined above and we are happy to consider evidence of transferable skills or experience which you may have gained outside the context of paid employment or education.

Please save all uploaded documents to show your name and the document type.

The application is to be submitted through the Varbi recruitment system.

The closing date for applications is midnight CEST on Sunday 30th April, 2023.

Working at Karolinska Institutet

For further information about working at Karolinska Institutet, rules for visa/residence permit, insurance and accommodation please see: International staff

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-04-30 at 23:59
Unit: at one of KI’s departments

Read the job description at the university homepage or apply.

Post expires on Sunday April 30th, 2023

Postdoctoral position in computational pathology and cancer precision medicine

Do you want to contribute to top quality medical research?

Call for Precision Medicine Postdocs within computational pathology/data science/AI Machine Learning – A unique collaboration between two of the world’s foremost medical institutions: Karolinska institutet & Oslo university hospital in partnership with AstraZeneca (pharmaceuticals)

Are you interested in identifying and implementing predictive biomarkers in Lung or Breast Cancer, using advanced predictive analytics and AI? Do you have the skills and the mindset to exploit health data from multiple sources using machine learning / AI towards improved diagnosis and outcomes for cancer patients? This is YOUR opportunity to join key experts from leading cancer institutes and AstraZeneca to make a difference for patients.

This position is focused on Breast Cancer and is based at Karolinska Institutet, Department of Medical Epidemiology and Biostatistics (MEB), Stockholm, Sweden.

Karolinska Institutet is one of the world’s foremost medical universities, KI accounts for the single largest share of all academic medical research conducted in Sweden. KI also offers the country’s broadest range of education in medicine and health sciences. The Department of Medical Epidemiology and Biostatistics (MEB) is among the largest departments of epidemiology and biostatistics in Europe. The Department consists of researchers, doctoral students, biostatisticians, data collectors and database administrators as well as administrative personnel, in total some 250 staff and is situated at campus Solna. Further information can be found at ki.se/meb..

Your mission

Our ambition is to discover innovative ways to stratify patients and to identify predictive and prognostic biomarkers by machine learning and AI. This postdoctoral position is focused on development and validation of methodologies for analysis and modelling of breast cancer histopathology image data together with clinical information. Machine learning and deep learning techniques are central in this computational pathology project aimed at improving phenotyping and patient stratification. The project is based on unique and large in-house datasets that include both image data together with clinical information and outcomes. The role would suit applicants who are interested in developing a career in AI/ML and data-driven cancer precision medicine.

Duration: 2 years initially with an additional 1 year merit-based extension.

Your profile

We are looking for passionate individuals in their final year of graduate studies (PhD or equivalent) or working as postdoctoral researchers within two years of receiving their PhD degree (Note: Final year graduates must have submitted and defended their PhD thesis prior to the preliminary start date)

We believe that you have a strong research background in e.g. applied AI/machine learning, computer vision, statistics or data science, and prior experience of medical research. The successful candidate will join an interdisciplinary research team that has strong collaborations with clinical experts and other national and international research groups.

Prior experience in Python programming, and prior experience of working with common deep learning frameworks, such as Tensorflow/Keras or Pytorch, is required. It is desirable that the candidate has prior experience from large-scale analysis of biomedical data and/or applied machine learning/deep learning/AI. Prior experience in computational pathology or medical image research in general is desirable.

The applicant should be able to collaborate as part of a team as well as independently and be able to organize and prioritise his/her own tasks with minimal supervision. Excellent written and oral communication skills in English are required.

Note: Successful applicants will require valid work visas for Schengen (EU EEA).

For further information please contact Associate Professor Mattias Rantalainen (email: mattias. rantalainen@ki.se)

What we offer

Successful candidates will be awarded a fully funded postdoctoral position, joining a vibrant scientific community within academia and pharma. If selected, you will have access to leading expertise, unique large-scale data, and the mentoring support needed to turn ideas into reality.

Both academic supervisors and AstraZeneca mentors will be assigned to each postdoctoral fellow, offering you the freedom and autonomy to contribute your unique skills, plus the support to rapidly learn new approaches to follow the science, innovate and make a tangible impact. You are expected to regularly present at national and internal workshops, seminars and conferences and contribute to publications in leading journals.

Karolinska Institutet is a state university, which entitles you to several benefits through our collective agreement.

Location: Solna

Choose to work at KI – Ten reasons why

 

Application

An employment application must contain the following documents in English or Swedish:

  • A cover letter that includes a summary of current work and statement of research interest (no more than one page)
  • A complete CV, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications

Welcome to apply at the latest 20th of April 2023

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-04-20 at 23:59
Unit: Department of Medical Epidemiology and Biostatistics

Read the job description at the university homepage or apply.

Post expires on Thursday April 20th, 2023

Postdoctoral studies in translational immunology focusing on autoimmunity and lymphoma in the skin (scholarship)

Do you want to contribute to top quality medical research?

Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Join our truly translational scientific constellation focusing on tissue inflammation: a creative and inspiring environment full of expertise and curiosity.

Division

The Department of Medicine, Solna, is one of the largest departments at Karolinska Institutet. The department consists of several units that are separated into different research groups. The core activities of the department are research, doctoral education and undergraduate education for medical and biomedical students. The research has three main profiles: allergy, cardiovascular medicine and inflammatory diseases.

The laboratory of Hanna Brauner is located in an excellent immunological research environment at the Centre for Molecular Medicine, CMM. The close proximity of the laboratory to the clinic at the Karolinska University Hospital also facilitates collaborations with clinicians of different fields and enables the analysis of fresh patient samples.

Duties

We seek a highly motivated postdoctoral fellow to join the team of MD PhD Hanna Brauner in focusing on finding novel pathogenic mechanisms and biomarkers for patients with autoimmunity and lymphoma.

We have access to unique clinical material, which we will assess in a truly translational approach, applying cutting edge methods to understand key clinical questions. The team of Hanna Brauner has a net-work of national and international collaborators among both basic science researcher and clinical researchers and is associated to the research group of professor Marie Wahren Herlenius.

Our main research interest is to understand pathways governing development of systemic inflammatory diseases and lymphoma and the link between those two, since patients with autoimmune diseases run an increased risk of developing lymphoma and other cancers. We will investigate possible immune mechanisms and tumor properties governing cancer development in patients with autoimmunity, including dermatomyositis and systemic lupus erythematosus. In addition, we focus on cutaneous T cell lymphoma, which is a rare type of lymphoma primarily engaging the skin. The unique accessibility of this disease allows for easy access to the tumor and the possibility to follow the development of the lymphoma and anti-lymphoma immune responses over time. Most of the patients with cutaneous T-cell lymphoma get an indolent disease, but for largely unknown reasons around 10-15% percent develop aggressive disease with high fatality. In these efforts our ultimate aims are to increase fundamental knowledge on the pathogenesis of cutaneous lymphoma and cancer in autoimmunity and aid earlier identification of patients at risk of aggressive disease. 

To reach our goal have set up a strong collaborative team of researchers and clinicians in dermatology, hematology, rheumatology, oncology, pathology, immunology and epidemiology to take a broad approach. Our research originates in clinical questions and patient material paired with high level basic science experimental investigations.

The position includes experimental work, primarily with clinical material and cell lines but possibly also animal experiments. Key techniques include in vitro assessments of immune cell phenotype and function, advanced flow cytometry, immunohistochemistry, spatial proteomics and transcriptomics, single cell RNA sequencing and confocal microscopy.

Entry requirements

Applicants are required to have a PhD in immunology, cell biology or another relevant field. A strong publication record and ability to draft manuscripts is also desired. The successful applicant further has strong interpersonal skills, motivation and organizational and executive capacity.

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Location

The position is located within the Department of Medicine, Solna. The department consists of twelve divisions and each division consists of several research groups. The position is located within the research group of Marie Wahren-Herlenius, research team Hanna Brauner. Please see our websites for more information:

https://staff.ki.se/people/hanna-brauner

https://ki.se/en/meds/hanna-brauner-team

https://centermolecularmed.wixsite.com/my-site/hanna-brauner-team

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-04-05 at 23:59
Unit: Rheumatology division

Read the job description at the university homepage or apply.

Post expires on Wednesday April 5th, 2023

Postdoctoral position in adaptive immunity and mRNA delivery

Do you want to contribute to improving human health?

We are looking for an ambitious postdoctoral fellow with solid immunology and mRNA delivery skills to join our highly accomplished team. We offer a stimulating environment in a rapidly moving research frontier. The successful candidate will be part of a cluster of other researchers working on similar topics. 

Your mission

The Buggert group conducts innovative studies on cell-mediated immunity in health, cancer, and viral diseases. These studies are translational in nature and involve the usage of cutting-edge bulk- and single-cell technologies, including high-parameter flow cytometry, gene-editing, mRNA delivery, RNA-seq, ATAC-seq, TCR-seq, and proteomics analysis to dissect the heterogeneity and function of memory T cell immunity. Through these platforms, we study various aspects of human memory T cell biology with an overall aim to i) investigate the heterogeneity of circulating and resident memory T cells in human organ donors, ii) identify alternative functions of memory T cells in human tissues, and iii) understand how we can improve current immunological therapies for diseases.

The postdoctoral candidate will work with questions centered on tissue imprints on T cell functions and the establishment of new mRNA delivery platforms to create CAR-T cells. The candidate will work in close collaboration with different members of the group to apply gene-editing technologies (e.g. CRISPR-Cas9) to mechanistically dissect different functions of human memory T cells in peripheral blood and tissues. As such, we are seeking a postdoctoral candidate with a PhD, who will work as an integrated member of our team, being involved in several ongoing projects and driving their project forward.

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

To be considered for employment as a postdoctoral candidate, in addition to holding a PhD in the field of biomedicine, the candidate must have demonstrated research expertise and documented research experience in the field of T cell immunology during his/her doctoral thesis work.

The candidate should have received training in biotechnology and immunology during their PhD studies and must fully master mRNA-delivery techniques. Experience in sequencing techniques, flow cytometry, and gene-editing techniques will also be considered as merits. Applicants should have first-author publications in recognized peer-reviewed journals, and fluency in English is a requirement.

It is particularly meritorious that the applicant has

  • Been trained in immunology during her/his PhD studies
  • Publications in the field of T cell immunology
  • Fully master mRNA-delivery platforms
  • Statistical knowledge
  • Generate flow cytometry data
  • Extensive cell culture background
  • Gene-editing technologies
  • Fluency in English

It is meritorious that the applicant has

  • Laboratory molecular and cell biology skill sets (e.g. preparation of RNAseq libraries)
  • Been trained in biotechnology during her/his Bachelor or Master studies

After an overall assessment of the expertise and merits of the applicants in relation to the subject area, Karolinska Institutet will determine which of them has the best potential to contribute to the positive development of the activities at KI.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.


Location:
Flemingsberg

Read more about the Center for Infectious Medicine

Read more about the Buggert group 

 

 

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

Welcome to apply at the latest 2023-03-31

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-03-31 at 23:59
Unit: Department of Medicine, Huddinge

Read the job description at the university homepage or apply.

Post expires on Friday March 31st, 2023

Four positions: SRP Diabetes Postdoctoral Fellowship Programme

Do you want to contribute to top quality medical research?

The Strategic Research Programme in Diabetes (SRP Diabetes) at Karolinska Institutet is funding a prestigious fellowship programme for postdoctoral research fellows. The Programme is focused on research in diabetes and its comorbidities. With this postdoctoral programme SRP Diabetes aims to support the next generation of exceptional young scientists within the diabetes area, including both experimental and clinical research. As part of this programme, we are now looking to recruit 4 outstanding postdoctoral research fellows. Full details on each project and contact information to the PIs can be found at: http://ki.se/en/srp-diabetes/postdoctoral-fellowships

Based at Karolinska Institutet, fellows will undertake a cutting-edge research project in a competitive lab and be part of the SRP Diabetes dynamic research environment where several events will be held throughout the year such as high-profile lectures, symposia, internal retreat, etc. which the fellows will attend

The fellowships are fully funded, and salary is provided for a 2-year period. It is our intention that the positions will start in the autumn of 2023, though some flexibility with the start date might be possible.

Available Research Projects

The following 4 projects are available (click each project to reach the corresponding job posting):

  1. Integrating transcriptomics and chemical biology for induction of ß-cells. Prinicipal Investigator: Olov Andersson
  2. Somatosensory networks control glucose homeostasis. Principal Investigator: Alessandro Furlan
  3. Investigating DNA damage as a driver of adipocyte senescence and inflammation in obese, hyperinsulinemic individuals. Principal Investigator: Kirsty Spalding
  4. Mapping the biodistribution of multivalent insulin variants in zebrafish and in mice. Principal Investigator: Ana Teixeira

Full details on each project and contact information for the PI’s can be found at: srp-diabetes/postdoctoral-fellowships

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

 

HOW TO APPLY

You can do one of the following:

a) go to this website https://ki.se/en/srp-diabetes/postdoctoral-fellowships to find detailed information on the projects and labs and the individual job postings with their online application form:

b) Directly click on the individual projects titles above to find the corresponding job posting and online application form

 

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-04-30 at 23:59
Unit: Department of Molecular Medicine and Surgery

Read the job description at the university homepage or apply.

Post expires on Sunday April 30th, 2023

Postdoctoral studies in immunology with focus on regulation of B cells and Macrophages in autoimmune disease (scholarship)

Do you want to contribute to future treatments of autoimmune disease?

In our research group we focus on investigating how B cell tolerance is broken to allow for production of autoantibodies that drives disease. We are studying how B cell interactions with innate immune cells including NKT cells, Macrophages and Neutrophils influence autoantibody production in connection to SLE and the comorbidity atherosclerosis. We have made several discoveries that we are now expanding on, including interactions between Neutrophils and NKT cells in the regulation of B cells (PNAS. 2020 21;117 and Nat. Immunol. 2016 12:1407). The focus now is how to modify these mechanisms for treatment purposes and find out which disease mechanisms that can be targeted.

Division and research group

Prof. Mikael Karlssons group is located at the Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet, in Solna (Biomedicum). The department conducts research and teaching in immunology, infectious biology, cell biology and cancer. Our keywords are interdisciplinary, clinically based basic research and national and international cooperation.

Duties and description of the project

The postdoc will focus on to understand how B cells interact with innate immune cells during the initial steps of activation and how this can lead to break of tolerance. We have recently generated novel mouse strains that are yet to be published and the postdoc will use these to study B cell activation. This includes conditional targeting of innate immune recognition pathways in macrophages and neutrophils as well as lineage tracing of regulatory B cells. Besides in vivo models the lab has experience in working with in vitro models for B cell activation and regulation as well as using patient material to verify findings. Findings in patients can also be further be tested in the in vivo models where we also aim to develop B cell specific treatments for autoimmunity. The project is done part in collaboration with UCL in Great Britain, Harvard University in the US and University of Toronto in Canada and the postdoc will interact with these institutions as well have the possibility to travel there.

Entry requirements

  • Candidates should have a strong background in immunology and demonstrate a promising publication record with at least one first-author peer-reviewed publication.
  • Proficiency in multi-parameter flow cytometry and mouse cancer models is a requirement.
  • Skills in bioinformatics and cell culture experience is an advantage.
  • The candidate should be self-motivated, have good communication skills and ability to interact effectively and work productively in a team. Emphasis in the recruitment will be on personal suitability.

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent. A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Location: Solna

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-03-31 at 23:59
Unit: Mikael Karlsson

Read the job description at the university homepage or apply.

Post expires on Friday March 31st, 2023

Phd position in Immunology

Do you want to contribute to top quality medical research?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

The group of Itziar Martinez-Gonzalez at the department of Microbiology, tumor- and cell biology (MTC) at Karolinska Institutet, is interested in studying memory ILC2s in type 2 immune diseases.

You find more information about our group here: https://ki.se/en/mtc/itziar-martinez-gonzalez-project-immunological-memory-of-innate-lymphoid-cells

The Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet conducts research and teaching within immunology, infection biology, cell biology and cancer. MTC have about 40 research groups and our key words are multidisciplinary, bridging, national and international collaborations.

The doctoral student project and the duties of the doctoral student

In this project, the doctoral student will develop an in-depth understanding of the role of ILC2s in the initiation and progression of hematological malignancies. The student will also develop a deep understanding of many cutting-edge techniques, including single cell multiomics, human sample analysis, mouse models of hematological disease, histological techniques and advanced flow cytometry. The student will also contribute to the general management and dynamics of the laboratory.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden.

As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

  1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
  2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
  3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

  • The candidate must hold a master degree in the field of immunology.
  • Ideally, the candidate would have previous experience in ILC research, mouse work and computational biology.
  • It is a merit if the applicant has some experience with flow cytometry analysis and sorting.

The candidate should be self-motivated, have good communications skills and a proven ability to interact effectively and work productively in a team. Fluency in English is a requirement. Personal skills are highly evaluated.  

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-03-30 at 23:59
Unit: Department of Microbiology, Tumor and Cell Biology

Read the job description at the university homepage or apply.

Post expires on Thursday March 30th, 2023

Postdoctoral Researcher in neutrophil biology

Do you want to contribute to top quality medical research?

The Center for Hematology and Regenerative Medicine (HERM) performs research and education in close collaboration with the Karolinska University Hospital. Our research team at HERM studies neutrophil biology and autophagy. Our goal is to improve treatments for neutropenic patients.

Your mission

The postdoctoral researcher will be involved in our ongoing efforts to improve the understanding of neutrophil function and interaction with mesenchymal stem cells. We are also working on neutrophil functional assays to characterize the neutrophil transfusion products. This work requires a creative approach to incorporate the functional assays and molecular work to dissect the research questions.

Your profile

We are looking for a talented, highly motivated postdoctoral researcher interested in neutrophil biology and autophagy. Documented experience in the following techniques is required:

  1. Flow cytometry
  2. Neutrophil functional assays (migration, phagocytosis and oxidative burst).
  3. Experience culturing mesenchymal stem cells
  4. Deep understanding of autophagy

The projects are pursued in an interdisciplinary environment that involves collaboration with several groups; therefore, good collaborative skills are necessary. Fluency in English is mandatory.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.


Location:
Flemingsberg

 Choose to work at KI – Ten reasons why

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

Welcome to apply at the latest 2023-03-30

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-03-30 at 23:59
Unit: Department of Medicine, Huddinge

Read the job description at the university homepage or apply.

Post expires on Thursday March 30th, 2023

Postdoctoral Researcher in single-cell asthma research

Do you want to contribute to top quality medical research?

We are looking for an ambitious postdoc with solid single-cell immunology skills to join our highly accomplished team of immunologists. We offer a stimulating environment in a rapidly moving research frontier.

Your mission

The Mjösberg group studies the development, regulation and function of innate lymphoid cells (ILCs) in humans, and how these cells contribute to pathology in mucosal organs such as the lung and gut. In this specific project, the postdoc will explore the lymphocyte landscape in bronchial biopsies of patients with severe asthma to identify ways of predicting and characterizing response to biologics therapy (read more here). The studies are translational as they involve advanced basic molecular and cellular immunological investigations of precious human tissue samples to discover novel disease mechanisms and therapy targets. The group is internationally recognized in the field through several high impact publications in recent years (Nat Immunol 2016, Cell Res 2021, Sci Imm 2022 etc).

The postdoc will continue the successful line of investigations utilizing single-cell techniques to dissect human ILC and T cell biology in healthy and diseased tissues. The project involves handling of human lung tissues and isolation of innate and adaptive lymphocytes, single-cell RNA-sequencing (scRNAseq), high resolution/spectral flow cytometry and in vitro cell-differentiation and co-culture assays. As this is a team effort, excellent communication skills are essential, as is proven ability to work in multidisciplinary teams. It is expected that the postdoc also participate in other ongoing projects, supervises students and other researchers if necessary, as well as contribute to common lab duties.

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

The candidate must hold a PhD equivalent to a Swedish doctoral degree in the field of immunology. The candidate must fully master multidimensional (>20 parameters) flow cytometry analysis and sorting, as well as be experienced in scRNAseq. The candidate should be familiar with R software and have some experience analyzing scRNAseq data. Experience in isolation and in vitro culturing of primary immune cells is a requirement, as is basic functional in vitro assessments of immune cell function such as intracellular cytokine stainings, ELISA etc. The candidate should have a strong publication track-record. The candidate should be self-motivated, have good communications skills and a proven ability to interact effectively and work productively in an interdiciplinary team. Fluency in English is a requirement.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.


Location:
 Flemingsberg


Read more about the Department of Medicine, Huddinge (MedH) and CIM

Read more about the project Tissue resident lymphocytes in severe asthma (TESLA)

 

 

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

Welcome to apply at the latest 2023-04-17

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-04-17 at 23:59
Unit: Department of Medicine, Huddinge

Read the job description at the university homepage or apply.

Post expires on Monday April 17th, 2023

Doctoral (PhD) student position in Tissue Microbiology

Do you want to contribute to top quality medical research?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

This doctoral position will be performed as part of Team Melican, one of 15 research teams which makes up AIMES.  AIMES, The center for the Advancement of Integrated Medical and Engineering Sciences is an interdisciplinary research center co-affiliated between Karolinska Institutet (KI) and the KTH Royal Institute of Technology (KTH). Research at AIMES is characterized by intimate interactions between pre-clinical and clinical scientists and researchers with natural sciences and engineering backgrounds. Biomedical research in infection and neuroscience is addressed by the development of cutting-edge approaches based on Organic Bioelectronics, Organ-on-Chip technology, and Tissue Microbiology, which combines expertise in electroactive polymers, chemistry, microfluidics, neurobiology, microbiology, physiology, pathology and intravital imaging. Other areas of research include renewable biomaterials, sensor technologies and anti-fouling surfaces. AIMES has an explicit aim to translate scientific findings to societal use via strong interactions with external stakeholders.

Team Melican, focusses on using cutting-edge tissue and animal models to study Bacterial Pathogenesis in vivo and in vitro. The team has expertise in numerous different bacterial pathogens and tissue models, with a particular interest in humanized skin models for studying bacterial skin and soft-tissue infections.

The doctoral student project and the duties of the doctoral student

This project is part of a Novo Nordisk funded Interdisciplinary Synergy Grant which focusses on preventing invasive infection by interfering with bacterial communication in the context of human skin. This project is run in close collaboration with teams at the University of Copenhagen. The project will involve the development and optimization of human skin tissue models to study colonization and invasion by skin commensal bacteria and Staphylococcus aureus. The project will involve cell and tissue handling, the integration of new tissue modelling techniques, molecular microbiology approaches as well as in vivo animal work. The student will be expected to optimize and develop new methodological approaches to address the research questions.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

  1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
  2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
  3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

 

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

We are seeking a highly motivated person with a Masters degree in Biomedicine and an interest in bacterial pathogenesis and the molecular mechanisms of host-pathogen interaction.

Skills required include microbiology experience and demonstrated ability to work at BSL2 safety levels. Experience with cell and tissue models is also required.

Good inter-personal and communication skills in English is a must, both written and oral.

Experience working with Staphylococcus sp. is advantageous as is certified training in animal handling equivalent to EU standards. Experience with techniques for microscopy as well as protein and genomic analysis is desirable.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

https://staff.ki.se/people/keira-melican

https://aimes.se/

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-03-31 at 23:59
Unit: Department of Neuroscience

Read the job description at the university homepage or apply.

Post expires on Friday March 31st, 2023

Doctoral student – Prevention of stroke – Make My Day

Do you want to contribute to improving human health?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

Make My Day is a research project grounded in theories from occupational science, behavioural science, stroke prevention, and health technologies. The project is situated in the research group Health in Everyday Life among people with neurological Disability (HELD) in the division of occupational therapy at the Department of Neurobiology, Care Sciences, and Society (NVS). The project is also situated within the Unit for Research, Education, Development, and Innovation at Stockholms Sjukhem. These well-established research environments provide many possibilities for the doctoral student to meet other doctoral students, postdocs, research assistants, as well as senior and junior researchers.  Moreover, this is an environment in which the doctoral student can discuss and reflect on her/his own research as well as research internationally. The research group environments are interprofessional and include members with a background in occupational therapy, physiotherapy, speech therapy, design, public health, and medicine. There will be regular seminars and events to discuss research and education available to the doctoral student.

The doctoral student project and the duties of the doctoral student

Lifestyle factors such as tobacco use, food, and physical activity have a big impact on the risk for stroke and TIA. Primary healthcare has the potential to develop services using eHealth that specifically target stroke prevention. The project’s overarching aim is to study how next-of-kin perspectives and work perspectives can be integrated in an intervention as well as to update a and evaluate the feasibility of the interprofessional and eHealth based prevention program – Make My Day for persons with TIA. The doctoral student projects are part of a broader research program. Three studies will be included in the doctoral student plan and will be designed to include both qualitative and quantitative methods. Over the course of doctoral studies, the student will be expected to carry out data gathering, analyses, and writing of scientific articles with increasing impendence and under supervision. Courses and research seminars are an integral part of the doctoral education and the student is expected to attend actively. Furthermore, the doctoral student will be expected to present at national and international conferences as well as develop critical thinking in relation to carrying out and evaluating research. The doctoral student is expected to gain thorough knowledge within occupational science and related methods.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

  1. A) General eligibility requirement

    You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

 

  1. B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

A requirement is that the applicant has sufficient fluency in Swedish and English in order to gather qualitative data and conduct analyses in Swedish as well as write, present, and publish results in English. It is of merit if the applicant has a background in a field such as occupational therapy, physical therapy, or nursing with clinical experience within primary healthcare and rehabilitation.

Of importance will also be personal fit for the project. We are looking for a candidate who takes initiatives, is curious, and actively seeks knowledge. The candidate needs to be a collaborator, organized, independent, and flexible.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.


Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

 

All applicants will be informed when the recruitment is completed.

https://ki.se/en/nvs/make-my-day-prevention-of-stroke

 

Want to make a difference? Join us and contribute to better health for all

 

Deadline: 2023-03-31 at 23:59
Unit: Avdelningen för arbetsterapi

Read the job description at the university homepage or apply.

Post expires on Friday March 31st, 2023

Postdoctoral Researcher in Cancer Biology with Focus on Mutational Signatures

Do you want to contribute to top quality medical research?

We are looking for a motivated postdoc to be part of our research group with a focus on mixture toxicology at the Unit of Biochemical Toxicology, Institute of Environmental Medicine (IMM). The position is placed in the research group of Kristian Dreij in a project that aims to determine mutational signatures of environmental complex mixtures to improve the understanding of carcinogenesis.

Your mission

Experimentally determined mutational signatures have provided important insights into the agents and processes underlying the causes of human cancer. Although humans mainly are exposed to complex mixtures of agents which might contribute to cancer development, this research has so far exclusively focused on single mutagens. The overall objective of this project is to determine mutational signatures induced by environmental complex mixtures in human cells, thereby increasing the understanding of the mechanisms and role of mixtures vs single compounds in cancer etiology. This project is conceptually novel and expected to have important consequences on our understanding of mutational signatures and cancer development.

The post doc will primarily use basic cell biology methodologies together with next-generation sequencing to determine mutational signatures and gene expression profiles. The post doc will be responsible for bioinformatic analyses of the sequencing data together with collaborators and NBI Sweden. Other tasks include writing manuscripts and participating in meetings and discussions with partners as well as in teaching. The position is temporary for 2 years, with possibility of extension.

Your profile

We are looking for a highly motivated postdoctoral fellow who can work independently and develop his/her own ideas and visions and with a strong drive for a future career in research. The successful applicant must have a Ph.D. from an appropriate discipline such as toxicology, cell- or molecular biology with in-depth understanding of cellular signaling and carcinogenesis. A documented background in standard cell biology techniques is required. Documented hands-on experience of data analysis of next-generation sequencing data is required. Advanced understanding and experience of data analysis of whole genome sequencing data is particularly meritorious.

The candidate must be able to work well in a team with researchers from different disciplines, have good collaboration and communication skills and must be able to communicate well in English, both orally and in writing. In addition, personal suitability will be a factor in the selection process.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.


Location: 
Institute of Environmental Medicine, Solna.

For more information:
https://staff.ki.se/people/kristian-dreij
https://ki.se/en/imm/unit-of-biochemical-toxicology

 

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-04-04 at 23:59
Unit: The Institute of Environmental Medicine

Read the job description at the university homepage or apply.

Post expires on Tuesday April 4th, 2023

Doctoral (PhD) student position in Sensory Neuroscience

Do you want to contribute to top quality medical research?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

The aim of our research is to understand how the human sensory systems work. To achieve this, we conduct various research projects that attempt to link smell perception to brain processing using a range of different methods, including electrophysiological (EEG), functional (fMRI) and structural brain imaging (MRI), as well as behavioral and psychophysical measurements. In our research group, we use state-of-the art methods and develop new analysis methods for brain imaging. Here you will find a unique opportunity to work together with top researchers in the borderland between psychology and neuroscience to jointly try to understand how the sensory system works. We offer an engaging and international research environment where you get an opportunity to contribute to high-quality research at an international top level.

The doctoral student project and the duties of the doctoral student

In your role as a PhD student in the group, you will participate in a project that attempts to determine how breathing affects the human brain and perception the through brain imaging measurements (e.g. EEG fMRI). With the help of other team members, you will be responsible for setting up experiments, analysing data and writing scientific articles where the results from these experiments are reported.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

  1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
  2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
  3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

We are looking for you who like to collaborate, have very good analytical skills, and are curious about how the human brain processes sensory information (your background could for example be in engineering or neuroscience). It is highly meritorious to have previous experience with analyses of EEG and fMRI data. Furthermore, it is highly meritorious to have documented good knowledge of inference statistics and signal processing. It is highly meritorious to have good knowledge of the programs such as Matlab, Python, and R which are the group’s analysis tools. Applicants must also demonstrate a high degree of accuracy, initiative, and independence.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.


Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

Read more about the Department of Clinical Neuroscience 
Read more about the Perceptual Neuroscience Lab

Want to make a difference? Join us and contribute to better health for all!

Deadline: 2023-04-01 at 23:59
Unit: Department of Clinical Neuroscience

Read the job description at the university homepage or apply.

Post expires on Saturday April 1st, 2023

Postdoctoral Researcher in Psychology

Do you want to contribute to top quality medical research?

Your mission

The current postdoc position will focus on biomarkers of olfactory and cognitive function in aging and dementia. You will work with data collected at a Memory clinic (n = 250) and within the population-based Swedish National Study on Aging and Care-Kungsholmen (SNAC-K, n = 2500). Available biomarkers include CSF, blood, and neuroimaging markers. The Memory clinic sample is currently cross-sectional but follow-ups are ongoing. The SNAC-K study covers repeated assessments of olfaction, cognition, and dementia across 18 years. Over the course of the postdoctoral appointment, the candidate will plan, analyze, structure, and report on results from these and other databases.

This is a temporary full-time position of 2 years with start in June 2023.

Your profile

We are looking for a highly motivated and creative person who can work both independently and as a member of a team. The candidate should have a background in psychology or cognitive neuroscience. It is considered favorable if the candidate has knowledge within the fields of cognitive aging or olfactory cognition. Prior experience with longitudinal population-based databases and advanced statistical modelling is also an advantage. Excellent collaborative, communication and scientific writing skills are needed. Very good English skills in speaking and writing are an absolute requirement for the position. Independence and strong motivation are expected throughout the project.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

We stress research expertise within the specified areas when assessing applicants. In addition, great emphasis will be placed on collaborative ability, ability to work independently, and personal suitability.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.


Location:
ARC, Solna

Information about NVS

Information about ARC

Choose to work at KI – Ten reasons why

 

 

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

Welcome to apply at the latest 2023-03-28.

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-03-28 at 23:59
Unit: Aging Research Center, ARC

Read the job description at the university homepage or apply.

Post expires on Tuesday March 28th, 2023

Postdoctoral Researcher in <subject area>

Do you want to contribute to top quality medical research?

Research at the Institute of Environmental Medicine is carried out in four major areas: epidemiology, toxicology, physiology, environmental and occupational medicine. The institute offers an excellent international research and working environment, and has about 350 employees and associates. The institute also provides authorities in Sweden and EC as well as international organisations (e.g. WHO) with expertise on environmental health risk assessments.

The aim of the research at the unit Metals and Health is to identify toxic effects of metals in the general and in the work environment, to understand causal relationships between metal exposure and various diseases, and how susceptibility factors influence these relationships. We also study mechanisms of metal toxicity. We work both in vitro and using molecular epidemiology approaches. We now search for a postdoctoral researcher with competence in metal toxicology.   

Your mission

The successful applicant will work on toxicological studies of metals present in water and food using a combination of toxicogenomics, toxicoepigenomics, as well as traditional toxicological assays. As a postdoctoral researcher you will be involved in all steps of the project, i.e., experimental planning, data analysis, and writing manuscripts.

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

To be eligible, the candidate must have:

  • background in toxicology, biology, biochemistry or equivalent
  • experience of metal analysis
  • experience of epigenetic analysis
  • excellent writing and communication skills (English) as well as ability to work in a very structured way and enjoy collaborating

It is meritorious if the candidate has:

  • experience working with in vitro toxicity testing
  • experience or a strong interest in working with novel toxicological approaches such as RNA sequencing and bioinformatics 

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.


Location:
Solna

 

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

Welcome to apply.

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-03-27 at 23:59
Unit: The Institute of Environmental Medicine

Read the job description at the university homepage or apply.

Post expires on Monday March 27th, 2023