Do you want to contribute to top quality medical research?

We are looking for an ambitious postdoc with solid single-cell immunology skills to join our highly accomplished team of immunologists. We offer a stimulating environment in a rapidly moving research frontier.

Your mission

The Mjösberg group studies the development, regulation and function of innate lymphoid cells (ILCs) in humans, and how these cells contribute to pathology in mucosal organs such as the lung and gut. In this specific project, the postdoc will explore the lymphocyte landscape in bronchial biopsies of patients with severe asthma to identify ways of predicting and characterizing response to biologics therapy (read more here). The studies are translational as they involve advanced basic molecular and cellular immunological investigations of precious human tissue samples to discover novel disease mechanisms and therapy targets. The group is internationally recognized in the field through several high impact publications in recent years (Nat Immunol 2016, Cell Res 2021, Sci Imm 2022 etc).

The postdoc will continue the successful line of investigations utilizing single-cell techniques to dissect human ILC and T cell biology in healthy and diseased tissues. The project involves handling of human lung tissues and isolation of innate and adaptive lymphocytes, single-cell RNA-sequencing (scRNAseq), high resolution/spectral flow cytometry and in vitro cell-differentiation and co-culture assays. As this is a team effort, excellent communication skills are essential, as is proven ability to work in multidisciplinary teams. It is expected that the postdoc also participate in other ongoing projects, supervises students and other researchers if necessary, as well as contribute to common lab duties.

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

The candidate must hold a PhD equivalent to a Swedish doctoral degree in the field of immunology. The candidate must fully master multidimensional (>20 parameters) flow cytometry analysis and sorting, as well as be experienced in scRNAseq. The candidate should be familiar with R software and have some experience analyzing scRNAseq data. Experience in isolation and in vitro culturing of primary immune cells is a requirement, as is basic functional in vitro assessments of immune cell function such as intracellular cytokine stainings, ELISA etc. The candidate should have a strong publication track-record. The candidate should be self-motivated, have good communications skills and a proven ability to interact effectively and work productively in an interdiciplinary team. Fluency in English is a requirement.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location:  Flemingsberg

Read more about the Department of Medicine, Huddinge (MedH) and CIM

Read more about the project Tissue resident lymphocytes in severe asthma (TESLA)

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply at the latest 2023-04-17

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-04-17 at 23:59
Unit: Department of Medicine, Huddinge

Read the job description at the university homepage or apply.

Post expires on Monday April 17th, 2023

Do you want to contribute to top quality medical research?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

Department of Clinical Neuroscience (CNS) conducts research and education in the field of neuroscience from the molecular level to the society level. The clinical research and education is conducted in collaboration with other research groups from the Karolinska Institutet, with other universities as well as the Stockholm County Council.

Our research group is a translational and multidisciplinary research team studying movement and psychiatric disorders, particularly Parkinson’s disease and depression. We use cellular and animal models and analyse clinical samples and biopsies from patients. Our goals are to understand the molecular mechanisms underlying disease states, drug mechanisms and to identify novel biomarkers and medically relevant therapeutic targets.

The doctoral student project and the duties of the doctoral student

Disorders of the brain are among the biggest challenges facing public and personal health today. Major depression is one of the most frequent disorders of the brain and the majority of drugs used for its treatment affect signaling through the neurotransmitter serotonin (5-HT) in one way or another. Side effects of these drugs are common and many patients do not respond to treatment, such that there is a pressing need for new drugs with fewer side effects and enhanced efficacy. To develop such drugs, a more complete understanding of signaling in mood disorders is necessary. Towards this end, the Translational Neuropharmacology laboratory uses molecular, cellular and animal models in which the function of glutamate and serotonergic receptors are studied. Thanks to the breadth of methodological approaches, the laboratory is capable of translating results from molecular and cellular assays into the clinical stage using patient samples.

Over the course of the doctoral studies, the development of various behavioral, neurochemical, electrophysiological, molecular, and morphological analyses to evaluate the effects of the fast-acting antidepressant ketamine and its enantiomers will be a focus. The successful applicant will generate data that guide the development of novel pharmacological approaches (rapid-onset) to be tested in animal models of stress and depressive-like behavior. Independence and strong motivation are expected throughout the project. The candidate will be encouraged to serve as supervisor for exam students.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

Applicants should have an academic degree in Biological Sciences (Molecular Biology or Human Biology). Applicants must have a background in the mechanisms underpinning the pathophysiology of depression and fast-acting antidepressant agents, such as ketamine. A strong background in biochemical or behavioral paradigms, animal models of stress and depression, and extensive experience with methods of molecular and cellular neuroscience is a strength. In addition, candidates should have a solid knowledge of neuroscience and pharmacology in theory and practice. Ideal applicants will have spent part of their education in a foreign country, bringing international experience and a strong team spirit to the laboratory. Excellent command of the English language is requierd.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

Read more about the Department of Clinical Neurosience here
Read more about the research group here

Want to make a difference? Join us and contribute to better health for all!

Deadline: 2023-03-21 at 23:59
Unit: Department of Clinical Neuroscience

Read the job description at the university homepage or apply.

Post expires on Tuesday March 21st, 2023

Do you want to contribute to top quality medical research?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

This doctoral position will be performed as part of Team Melican, one of 15 research teams which makes up AIMES.  AIMES, The center for the Advancement of Integrated Medical and Engineering Sciences is an interdisciplinary research center co-affiliated between Karolinska Institutet (KI) and the KTH Royal Institute of Technology (KTH). Research at AIMES is characterized by intimate interactions between pre-clinical and clinical scientists and researchers with natural sciences and engineering backgrounds. Biomedical research in infection and neuroscience is addressed by the development of cutting-edge approaches based on Organic Bioelectronics, Organ-on-Chip technology, and Tissue Microbiology, which combines expertise in electroactive polymers, chemistry, microfluidics, neurobiology, microbiology, physiology, pathology and intravital imaging. Other areas of research include renewable biomaterials, sensor technologies and anti-fouling surfaces. AIMES has an explicit aim to translate scientific findings to societal use via strong interactions with external stakeholders.

Team Melican, focusses on using cutting-edge tissue and animal models to study Bacterial Pathogenesis in vivo and in vitro. The team has expertise in numerous different bacterial pathogens and tissue models, with a particular interest in humanized skin models for studying bacterial skin and soft-tissue infections.

The doctoral student project and the duties of the doctoral student

This project is part of a Novo Nordisk funded Interdisciplinary Synergy Grant which focusses on preventing invasive infection by interfering with bacterial communication in the context of human skin. This project is run in close collaboration with teams at the University of Copenhagen. The project will involve the development and optimization of human skin tissue models to study colonization and invasion by skin commensal bacteria and Staphylococcus aureus. The project will involve cell and tissue handling, the integration of new tissue modelling techniques, molecular microbiology approaches as well as in vivo animal work. The student will be expected to optimize and develop new methodological approaches to address the research questions.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

We are seeking a highly motivated person with a Masters degree in Biomedicine and an interest in bacterial pathogenesis and the molecular mechanisms of host-pathogen interaction.

Skills required include microbiology experience and demonstrated ability to work at BSL2 safety levels. Experience with cell and tissue models is also required.

Good inter-personal and communication skills in English is a must, both written and oral.

Experience working with Staphylococcus sp. is advantageous as is certified training in animal handling equivalent to EU standards. Experience with techniques for microscopy as well as protein and genomic analysis is desirable.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

https://staff.ki.se/people/keira-melican

https://aimes.se/

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-03-31 at 23:59
Unit: Department of Neuroscience

Read the job description at the university homepage or apply.

Post expires on Friday March 31st, 2023

Do you want to contribute to improving human health?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

Make My Day is a research project grounded in theories from occupational science, behavioural science, stroke prevention, and health technologies. The project is situated in the research group Health in Everyday Life among people with neurological Disability (HELD) in the division of occupational therapy at the Department of Neurobiology, Care Sciences, and Society (NVS). The project is also situated within the Unit for Research, Education, Development, and Innovation at Stockholms Sjukhem. These well-established research environments provide many possibilities for the doctoral student to meet other doctoral students, postdocs, research assistants, as well as senior and junior researchers.  Moreover, this is an environment in which the doctoral student can discuss and reflect on her/his own research as well as research internationally. The research group environments are interprofessional and include members with a background in occupational therapy, physiotherapy, speech therapy, design, public health, and medicine. There will be regular seminars and events to discuss research and education available to the doctoral student.

The doctoral student project and the duties of the doctoral student

Lifestyle factors such as tobacco use, food, and physical activity have a big impact on the risk for stroke and TIA. Primary healthcare has the potential to develop services using eHealth that specifically target stroke prevention. The project’s overarching aim is to study how next-of-kin perspectives and work perspectives can be integrated in an intervention as well as to update a and evaluate the feasibility of the interprofessional and eHealth based prevention program – Make My Day for persons with TIA. The doctoral student projects are part of a broader research program. Three studies will be included in the doctoral student plan and will be designed to include both qualitative and quantitative methods. Over the course of doctoral studies, the student will be expected to carry out data gathering, analyses, and writing of scientific articles with increasing impendence and under supervision. Courses and research seminars are an integral part of the doctoral education and the student is expected to attend actively. Furthermore, the doctoral student will be expected to present at national and international conferences as well as develop critical thinking in relation to carrying out and evaluating research. The doctoral student is expected to gain thorough knowledge within occupational science and related methods.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

1. A) General eligibility requirement

   You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

1. B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

A requirement is that the applicant has sufficient fluency in Swedish and English in order to gather qualitative data and conduct analyses in Swedish as well as write, present, and publish results in English. It is of merit if the applicant has a background in a field such as occupational therapy, physical therapy, or nursing with clinical experience within primary healthcare and rehabilitation.

Of importance will also be personal fit for the project. We are looking for a candidate who takes initiatives, is curious, and actively seeks knowledge. The candidate needs to be a collaborator, organized, independent, and flexible.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

https://ki.se/en/nvs/make-my-day-prevention-of-stroke

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-03-31 at 23:59
Unit: Avdelningen för arbetsterapi

Read the job description at the university homepage or apply.

Post expires on Friday March 31st, 2023

Do you want to contribute to top quality medical research?

We are looking for a motivated postdoc to be part of our research group with a focus on mixture toxicology at the Unit of Biochemical Toxicology, Institute of Environmental Medicine (IMM). The position is placed in the research group of Kristian Dreij in a project that aims to determine mutational signatures of environmental complex mixtures to improve the understanding of carcinogenesis.

Your mission

Experimentally determined mutational signatures have provided important insights into the agents and processes underlying the causes of human cancer. Although humans mainly are exposed to complex mixtures of agents which might contribute to cancer development, this research has so far exclusively focused on single mutagens. The overall objective of this project is to determine mutational signatures induced by environmental complex mixtures in human cells, thereby increasing the understanding of the mechanisms and role of mixtures vs single compounds in cancer etiology. This project is conceptually novel and expected to have important consequences on our understanding of mutational signatures and cancer development.

The post doc will primarily use basic cell biology methodologies together with next-generation sequencing to determine mutational signatures and gene expression profiles. The post doc will be responsible for bioinformatic analyses of the sequencing data together with collaborators and NBI Sweden. Other tasks include writing manuscripts and participating in meetings and discussions with partners as well as in teaching. The position is temporary for 2 years, with possibility of extension.

Your profile

We are looking for a highly motivated postdoctoral fellow who can work independently and develop his/her own ideas and visions and with a strong drive for a future career in research. The successful applicant must have a Ph.D. from an appropriate discipline such as toxicology, cell- or molecular biology with in-depth understanding of cellular signaling and carcinogenesis. A documented background in standard cell biology techniques is required. Documented hands-on experience of data analysis of next-generation sequencing data is required. Advanced understanding and experience of data analysis of whole genome sequencing data is particularly meritorious.

The candidate must be able to work well in a team with researchers from different disciplines, have good collaboration and communication skills and must be able to communicate well in English, both orally and in writing. In addition, personal suitability will be a factor in the selection process.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Institute of Environmental Medicine, Solna.

For more information:
https://staff.ki.se/people/kristian-dreij
https://ki.se/en/imm/unit-of-biochemical-toxicology

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-04-04 at 23:59
Unit: The Institute of Environmental Medicine

Read the job description at the university homepage or apply.

Post expires on Tuesday April 4th, 2023

Do you want to contribute to top quality medical research?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

The aim of our research is to understand how the human sensory systems work. To achieve this, we conduct various research projects that attempt to link smell perception to brain processing using a range of different methods, including electrophysiological (EEG), functional (fMRI) and structural brain imaging (MRI), as well as behavioral and psychophysical measurements. In our research group, we use state-of-the art methods and develop new analysis methods for brain imaging. Here you will find a unique opportunity to work together with top researchers in the borderland between psychology and neuroscience to jointly try to understand how the sensory system works. We offer an engaging and international research environment where you get an opportunity to contribute to high-quality research at an international top level.

The doctoral student project and the duties of the doctoral student

In your role as a PhD student in the group, you will participate in a project that attempts to determine how breathing affects the human brain and perception the through brain imaging measurements (e.g. EEG fMRI). With the help of other team members, you will be responsible for setting up experiments, analysing data and writing scientific articles where the results from these experiments are reported.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

We are looking for you who like to collaborate, have very good analytical skills, and are curious about how the human brain processes sensory information (your background could for example be in engineering or neuroscience). It is highly meritorious to have previous experience with analyses of EEG and fMRI data. Furthermore, it is highly meritorious to have documented good knowledge of inference statistics and signal processing. It is highly meritorious to have good knowledge of the programs such as Matlab, Python, and R which are the group’s analysis tools. Applicants must also demonstrate a high degree of accuracy, initiative, and independence.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

Read more about the Department of Clinical Neuroscience 
Read more about the Perceptual Neuroscience Lab

Want to make a difference? Join us and contribute to better health for all!

Deadline: 2023-04-01 at 23:59
Unit: Department of Clinical Neuroscience

Read the job description at the university homepage or apply.

Post expires on Saturday April 1st, 2023

Do you want to contribute to top quality medical research?

Your mission

The current postdoc position will focus on biomarkers of olfactory and cognitive function in aging and dementia. You will work with data collected at a Memory clinic (n = 250) and within the population-based Swedish National Study on Aging and Care-Kungsholmen (SNAC-K, n = 2500). Available biomarkers include CSF, blood, and neuroimaging markers. The Memory clinic sample is currently cross-sectional but follow-ups are ongoing. The SNAC-K study covers repeated assessments of olfaction, cognition, and dementia across 18 years. Over the course of the postdoctoral appointment, the candidate will plan, analyze, structure, and report on results from these and other databases.

This is a temporary full-time position of 2 years with start in June 2023.

Your profile

We are looking for a highly motivated and creative person who can work both independently and as a member of a team. The candidate should have a background in psychology or cognitive neuroscience. It is considered favorable if the candidate has knowledge within the fields of cognitive aging or olfactory cognition. Prior experience with longitudinal population-based databases and advanced statistical modelling is also an advantage. Excellent collaborative, communication and scientific writing skills are needed. Very good English skills in speaking and writing are an absolute requirement for the position. Independence and strong motivation are expected throughout the project.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

We stress research expertise within the specified areas when assessing applicants. In addition, great emphasis will be placed on collaborative ability, ability to work independently, and personal suitability.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: ARC, Solna

Information about NVS

Information about ARC

Choose to work at KI – Ten reasons why

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply at the latest 2023-03-28.

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-03-28 at 23:59
Unit: Aging Research Center, ARC

Read the job description at the university homepage or apply.

Post expires on Tuesday March 28th, 2023

Do you want to contribute to top quality medical research?

Research at the Institute of Environmental Medicine is carried out in four major areas: epidemiology, toxicology, physiology, environmental and occupational medicine. The institute offers an excellent international research and working environment, and has about 350 employees and associates. The institute also provides authorities in Sweden and EC as well as international organisations (e.g. WHO) with expertise on environmental health risk assessments.

The aim of the research at the unit Metals and Health is to identify toxic effects of metals in the general and in the work environment, to understand causal relationships between metal exposure and various diseases, and how susceptibility factors influence these relationships. We also study mechanisms of metal toxicity. We work both in vitro and using molecular epidemiology approaches. We now search for a postdoctoral researcher with competence in metal toxicology.   

Your mission

The successful applicant will work on toxicological studies of metals present in water and food using a combination of toxicogenomics, toxicoepigenomics, as well as traditional toxicological assays. As a postdoctoral researcher you will be involved in all steps of the project, i.e., experimental planning, data analysis, and writing manuscripts.

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

To be eligible, the candidate must have:

• background in toxicology, biology, biochemistry or equivalent
• experience of metal analysis
• experience of epigenetic analysis
• excellent writing and communication skills (English) as well as ability to work in a very structured way and enjoy collaborating

It is meritorious if the candidate has:

• experience working with in vitro toxicity testing
• experience or a strong interest in working with novel toxicological approaches such as RNA sequencing and bioinformatics 

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply.

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-03-27 at 23:59
Unit: The Institute of Environmental Medicine

Read the job description at the university homepage or apply.

Post expires on Monday March 27th, 2023

Do you want to contribute to top quality medical research?

We are looking to recruit a postdoctoral researcher that will study the role of mitochondria in skin biology with focus on wound healing.

Your mission

The postdoctoral fellow will run a project that in depth examines how cell biology in general and mitochondria in specific is affected in normal and impaired skin wound healing.

Division
The Dermatology and Venereology unit is located in buildings at the Centre of Molecular Medicine (CMM; http://cmm.ki.se/). The research is performed in an interdisciplinary setting with strong collaboration with clinical departments and other national and international research groups. The principal investigator Dr Jakob Wikström, MD PhD, work in close collaboration with the other dermatology oriented research groups.

Your profile

Applicants should have a PhD degree within the area of biomedical research and have strong interest in medical and biological problems. We are looking for a senior postdoc with experience in basic dermatology research and mitochondrial research. The applicant should be able to independently perform cell culture, gene manipulation, confocal microscopy, and qPCR as well as mitochondrial assays such as respirometry. A documented interest in mitochondrial biology is qualifying. The applicant must be able to handle human samples. The ideal candidate should be able to work independently but at the same time also be a team player and be able to collaborate with the rest of the group.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location

The position is located within the Department of Medicine, Solna. The department consists of twelve divisions and each division consists of several research groups. The position is located within the research group of Jakob Wikström which is part of the Dermato-venereology division and located at the Centre for Molecular Medicine 

https://centermolecularmed.wixsite.com/my-site/jakob-wikström-group

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-03-24 at 23:59
Unit: Dermatology and venereology division

Read the job description at the university homepage or apply.

Post expires on Friday March 24th, 2023

Do you want to contribute to top quality medical research?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

As a doctoral student you will join our research group at the Marianne Bernadotte Center within the Division of Eye and Vision at the Department of Clinical Neuroscience. The overall goal of our research is to use measurements of eye and vision to understand the workings of the human brain in both health and disease, and to improve our knowledge of how the visual system develops and functions across the life span. Most of our research involves eye tracking, typically in a clinical context with a neurological condition or cognitive deficit in focus. Our team is interdisciplinary, which means that you will get to work closely with colleagues with expertise from different scientific fields (e.g., optometry and ophthalmology, psychology, computational linguistics and more).

The doctoral student project and the duties of the doctoral student

Vision is a highly active process and our eyes never stop moving. Even when we attempt to fixate our gaze on a steady visual target, we make small eye movements beyond our awareness commonly known as fixational eye movements. Microsaccades, the largest type of fixational eye movement, have long been of interest in eye movement research and visual neuroscience, in part because they are largely beyond volitional control and produced without the observer’s awareness, and in part because their functional significance to human vision has proven difficult to explain. Furthermore, in the past two decades a surge of research has shown that microsaccades are related to many aspects of visual perception, attention, and cognition, and thus potentially carry important information about brain function and neurological disease.

The purpose of this research project is to use machine learning methods to advance our understanding of fixational eye movements and how this type of eye movements may be affected by neurological conditions. The project will draw on recent advances in both reinforcement learning and supervised machine learning to better understand the spatiotemporal dynamics of these eye movements, as well as to identify early risk markers that might be useful in screening for neurodegenerative diseases.

It is not a requirement to be skilled in both reinforcement learning and supervised learning to apply for the position. A highly motivated applicant who has experience in only one of the two methodologies (reinforcement learning or supervised learning) will have the opportunity to learn the other during the project. As a PhD student in this project, you will record and analyze eye tracking data, design and implement machine learning workflows and computational models in Python, and perform statistical analysis in R and/or Python. You will be trained in all parts of the scientific process and actively be involved in all aspects of the research project, including planning, setting-up and running experiments, as well as writing manuscripts and publishing and presenting research findings in scientific journals and at international conferences.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

We are looking for a highly motivated PhD student who is interested in learning more about the fascinating relationship between the eye, vision, and the brain. We believe that you hold a degree in computer science, cognitive science, or psychology (or a related field dealing with computation and/or the human mind). You have an interest in how artificial intelligence (AI) and machine learning can be combined with sensor technologies, such as eye tracking, to learn more about the human nature. If you think you match this profile, you are particularly encouraged to apply.

In order to succeed in this role, we believe that you have:

• Programming and data analysis skills, ideally in Python and R.
• Machine learning skills in supervised learning (e.g., experience with Scikit-learn, TensorFlow, Keras or related libraries) and/or reinforcement learning (e.g., experience with OpenAI Gym, PyQlearning, Keras-RL or related libraries).
• Strong writing and oral communication skills in English.

In addition, it is an advantage, but not essential, if you have:

• Experience with performing eye tracking experiments or using other advanced sensor technologies.
• Experience with analyzing eye tracking data or other time series data.
• Experience of scientific writing and communication (e.g., having presented or published results at a conference or in a scientific journal.)

Moreover, it is important that you can work independently and take great responsibility for your own work tasks while also cooperating well with others. Your overall suitability for pursuing a doctoral education will be considered when filling the position.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

Read more about the research group here

Choose to work at KI – Ten reasons why

Want to make a difference? Join us and contribute to better health for all!

Deadline: 2023-04-25 at 23:59
Unit: Department of Clinical Neuroscience

Read the job description at the university homepage or apply.

Post expires on Tuesday April 25th, 2023

Do you want to contribute to top quality medical research?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The Department of Medical Epidemiology and Biostatistics conducts research in epidemiology and biostatistics across a broad range of areas within biomedical science. The department is among the largest of its type in Europe and has especially strong research profiles in psychiatric, cancer, reproductive, pediatric, pharmaco, genetic, and geriatric epidemiology, eating disorders, and biostatistics. Our department consists of researchers, doctoral students, biostatisticians, data collectors and database administrators as well as administrative personnel, in total some 270 staff.

The department is situated at campus Solna. Further information can be found at ki.se/en/meb.

The research group

The geriatric pharmacoepidemiological group’s mission is to investigate and improve drug utilization among older adults. Our research areas include inappropriate medication use, polypharmacy, register-based pharmacoepidemiology, medication use in frail older adults and inequality in medication use. Besides medication use, we also conduct research in related areas such as health, Covid-19, and use of health- and eldercare in older adults. The research group is led by Professor Kristina Johnell (https://staff.ki.se/people/kristina-johnell). We belong to the aging research group at MEB.

The doctoral student project and the duties of the doctoral student

The doctoral student project will investigate medication use in older adults, with a special focus on the process of deprescribing, using national register data. The project will include statistical analyses of national registers in order to investigate the frequency, the determinants, and benefit/harms of deprescribing in older adults. The PhD student will learn to master a broad range of methods, including epidemiological analysis of large Swedish registers.

What do we offer?

Ten reasons to work at KI
Career support for doctoral students
International staff

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

1. A) General eligibility requirement

   You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

• have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
• have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
• have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

1. B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

• Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

We attach great importance to personal qualities in this recruitment. As a person, you are independent, pay attention to detail, analytical, communicative and have excellent collaborative skills. 

• It is meritorious to have conducted research, including documented published research articles in international peer-reviewed scientific journals.
• Topic knowledge in geriatric pharmacoepidemiology, aging epidemiology, or related areas are meritorious.
• Previous experience of extracting, managing and analyzing large data materials is meritorious.
• Documented knowledge in use of standard statistical software , such as Stata, SAS or R is required.
• Excellent skills in English, both written and oral, is required.
• Knowledge in Swedish is an advantage.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-04-11 at 23:59
Unit: Department of Medical Epidemiology and Biostatistics

Read the job description at the university homepage or apply.

Post expires on Tuesday April 11th, 2023

Do you want to contribute to top quality medical research?

The Department of Dental Medicine at Campus Flemingsberg focuses on the education of dentists and dental hygienists. In addition, we perform research, dental specialization training and provide patient care. Karolinska Institutet and the rest of Scandinavia have been world leaders in dentistry for decades.

Division

The Department of Dental Medicine works with research and education within dental medicine and medicine with clinical training sites for future dental surgeons. We offer a top international learning and research environment for researchers, students, technical and administrative personnel. In KI´s new ANA Futura laboratory we are creating a leading translational integrated research environment equipped for cutting-edge research, where the boundaries between departments and clinics are torn down and researchers collaborate on the basis of common research profiles.

Location

A postdoc scholarship position is available in the research group of Prof. Margaret Sällberg Chen  https://staff.ki.se/people/marche at the Division of Oral Diagnostics and Rehabilitation, Section for Oral Diagnostics and Surgery. The scholarship position is for 1 year with possibility for extension.

Duties

This postdoctoral research position is immediately available in the research group of Prof Margaret Sällberg Chen. It is suitable for a scientist with research background on microbiota and human health. The candidate will join a multidisciplinary team that investigates mechanistic pathways in prevention of chronic disorders and cancer The focus of this postdoctoral study will be oral microbes and host cell interactions in human health, including microbial functions and responses to novel drug treatments.

The team recently discovered that oral microbiota can translocate into pancreatic tumors (GUT 2019, Front Immunol 2020) and has isolated the microbiota with implications in pancreas carcinogenesis (Gut Microbes 2021, J Proteome Res 2021). The group is active in developing translational studies to support cancer patient diagnostic and cancer prevention strategies (J Hepatol. 2019, JCI Insight 2021, Leukemia 2021, EBioMedicine 2021, Immunity 2022, Blood 2022). The candidate will learn our novel research models and participate in collaborative studies with possibility to discover new diagnostic/therapeutic biomarkers. The work will be conducted in an innovative and friendly environment with focus on diagnostics and precision health.

The position is suitable for highly motivated researchers who are strong in molecular biology as well as microbiological methods. Good laboratory knowledge in culture of bacteria and/or fungi, human cells, and PCR related analysis is a must. Familiar with human sample processing and biobanking, RNA/DNA preparation for microbiome analysis. The studies require good organisational and analytical skills. Interest in assay standardisation and biostatistics is a plus.

Qualifications

To qualify the applicant must hold a doctoral degree or a foreign qualification equivalent to a doctorate. A PhD in life science, biomedicine or biomedical sciences within subjects of microbiology, molecular biology or equivalent is preferred. In additional to laboratory experiences, he or she should have good writing and presentation skills. Applicants must have excellent communication skills in English.

Entry requirements

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.

A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent. To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable. 

Application process

An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)
• Motivation letter
• Name of two references

The application is to be submitted on the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-03-27 at 23:59
Unit: Department of Dental Medicine

Read the job description at the university homepage or apply.

Post expires on Monday March 27th, 2023

Do you want to contribute to top quality medical research?

The research group of Professor Johan Hartman at the Oncology-Pathology department performs clinical and translational studies for breast cancer, with a special focus on precision medicine.
The aim is to predict better individual patients’ unique drug sensitivity, as well as to understand the role of tumor heterogeneity and tumor-stromal interactions in breast cancer disease progression. We have a well-established research platform and organization using a multitude of pathology, genetic, and transcriptomic methods in a concerted effort to identify key factors that lead to resistance to current treatment regimens for breast cancer, as well as to identify novel biomarkers for the development of new diagnostic tools. The successful candidate will have access to our unique patient datasets and is expected to perform top-level breast cancer studies together with our collaborators at both KI, KTH, and Science for Life Laboratory.

Your mission

We are looking for a highly motivated postdoc with strong bioinformatics background to join our multidisciplinary team consisting of clinicians, bioinformaticians, computer scientists, and biologists. The postdoc candidate’s main tasks will be establishing pipelines for analyzing gene expression data from bulk-/single-cell RNA-sequencing, spatial transcriptomics, and other platforms (e.g., microarray or digital multiplexed gene expression platforms). DNA sequencing (WES or targeted sequencing of gene panels) and chromatin accessibility sequencing (ATAC-seq) will also be carried out. The postdoc candidate will participate in the somatic mutation and copy number alteration analysis concerning the interplay between tumor heterogeneity and treatment resistance mechanisms.

Your profile

To be eligible for employment as a postdoc, a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered an advantage if you have completed your doctoral degree within the last three years; if there are special reasons, your degree may have been completed earlier. The successful applicant should have the following qualifications:

Absolute requirements:

• A Ph.D. degree in bioinformatics, computational biology, molecular biology, computer science, or an equivalent quantitative area.
• Proficiency in a scripting language like R/Python, as well as the ability to work efficiently in a Linux command-line environment.
• Prior experience with gene expression analysis of high-throughput data and/or DNA-sequencing data analysis, supported by publications.
• Knowledge of molecular biology and interest in learning more.
• Excellent interpersonal communication skills (written and verbal English).
• Good data management and documentation skills.

Desired competencies:

• Experience in single-cell or spatial transcriptomics analyses or multi-omics integration analysis.
• Knowledge of tumor biology and/or histology.
• Experience in biostatistics or machine learning approaches.
• Experience in cancer-related databases, such as TCGA, COSMIC, dbSNP, etc

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: The position is located within the Oncology-Pathology department, mainly at Cancer Centrum Karolinska (CCK) in Solna. The position is located within the research group of Prof. Johan Hartman.

Links: https://hartmanlab.org/

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications 
• A summary of current work (no more than one page)

Welcome to apply at the latest April 3^th . 

The application is to be submitted through the Varbi recruitment system.

This position will last for two years. 

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-04-03 at 23:59
Unit: Forskargrupp Hartman

Read the job description at the university homepage or apply.

Post expires on Monday April 3rd, 2023

The Department of Medical Epidemiology and Biostatistics (MEB) is among the largest departments of epidemiology in Europe with special focus on increasing our knowledge of the aetiology of different diseases. Our department consists of researchers, doctoral students, biostatisticians, data collectors and database administrators as well as administrative personnel, in total some 250 staff. The department is situated at campus Solna. Further information can be found at ki.se/meb

Do you want to contribute to top quality medical research?

The research group at the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet in Stockholm has a broad research interest in women’s and children’s health. The primary focus is to understand and map sex specific risk factors, etiology and long-term consequences of preterm birth on neuropsychiatric and related disorders. A second research area is women’s health in relation to pregnancy and childbirth.

Your mission

In a collaboration between the Karolinska Institutet in Sweden, the Icahn School of Medicine at Mount Sinai, New York and the Chinese University Hong Kong you will participate in world-leading medical research to fill critical knowledge gaps using modern statistical and epidemiological methods.

The research program aims to (1) gain a comprehensive understanding of sex specific risks for neuropsychiatric disorders, with focus on autism; (2) determine causes for preterm birth and it’s consequences on neuropsychiatric disorders and children’s health, and (3) examine determinants for women’s health and it’s consequences on children’s health.

You will have access to world unique databases compiled from national registers in the Nordic countries and Israel as well as a longitudinal cohort study of 50,000 women with repeatedly collected information on lifestyle factors and medical conditions. You will work in an international research group and apply statistical methods for life-course epidemiological analyses. You will have the opportunities to initiate and lead the work from planning phase to publication of research manuscripts. You will also participate as an expert in collaborative studies.

You will publish, as lead as well as co-author, in peer review high impact journals.

Please check the link below for our latest publications, https://www.ncbi.nlm.nih.gov/myncbi/1TESiepxI0_kr/bibliography/public/

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

You have a background in medicine, public health, statistics or epidemiology and a PhD in statistics, epidemiology or similar and have experience in performing large-scale data analysis using standard statistical software. SAS is our primary software for data management and statistical analyses but experience of R is an advantage. Other software skills e.g. Python, Stata and UNIX is an advantage. You should have experience in survival analyses. Examples of statistical methods used are Cox regression, logistic regression and poisson regression, including various methods to deal with correlated data, confounding, modification and mediation. There are ample possibilities in attending courses in statistics, epidemiology, computer programming and similar.

A track record in writing scientific publications in English is required, and publications in high-impact journals is a merit. International research experience is preferred. Experience of presenting at international conferences is a merit.

The applicant should be experienced in working in a multidisciplinary context, possess communication and organizational skills, and know how to successfully multitask. Experience of the Nordic registers may be beneficial.

Important personal characteristics are that you are meticulous, analytical and structured.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna

Choose to work at KI – Ten reasons why

KI Postdoc Association

International staff

Stockholm Dual Career Network | International spouse network

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply at the latest March 28 2023.

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-03-28 at 23:59
Unit: Department of Medical Epidemiology and Biostatistics

Read the job description at the university homepage or apply.

Post expires on Tuesday March 28th, 2023

Do you want to contribute to improving human health?

Please join my team of world-leading bioinformaticians working across the globe in Mount Sinai Hospital in New York to Karolinska Institutet in Sweden and Tartu University Hospital in Estonian. Our main source of systems genetics analyses is the cardiovascular disease (CVD) STARNET (Stockholm-Tartu Atherosclerosis Reverse Network Engineering Task) study – a high-dimensional, multi-tissue genetics-of-gene/protein-expression database of  >1500 patients with and without CVDs. We study the network biology within and across organs to individual cells to better understand the complex etiologies of CVDs.

Your mission

You will take on the main responsibility of STARNET data within my lab at Karolinska Institutet and in collaborations within the EU and elsewhere. You will not require to develop new bioinformatic tools but to use state-of-the-art methodologies for QC, normalization, correlation and differential expression analyses, protein and gene expression quantitative trait loci (QTLs), co-expression network analysis like WGCNA, directed network analysis using probabilistic and machine learning (e.g., GENIE3) analyses as well as other deep and machine learning methods for data mining and statistical pattern recognition. Examples of integrative analyses, with for instance GWAS, are colocalization, mendelian randomization and transcriptome-wide analyses (TWAS such as SMR, MetaXcan and Coloc). Other roles will include data protection, sharing and cloud storage. You are also expected to help draft manuscripts and grants with emphasis on data illustrations and visualization.

Your profile

We are looking for an experienced person with extensive bioinformatical knowledge in the field of systems genetics – integrating DNA and RNA sequencing with proteomics and clinical information from one or more datasets (e.g., GWAS). The applicant should have substantial proficiency working in a Linux environment, as well as possess expertise in the coding languages of Python and R. Experience of working with a computing server is required. 

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

The candidate should have been trained in computer science, bioinformatics, or computational biology during her/his Ph.D. studies. The candidate should fully master (requirement) Python (Python Data Stack tools such as NymPY, SciPY, Pandas, scikit), be proficient in R, and have solid Unix/Linux experience and statistical knowledge. Experience working with high-performance computing is an advantage. The candidate should have experience in genome-wide NGS data analysis, particularly in working with bulk-RNAseq, scRNAseq and scATACseq from FASTQ to analyze data with 10x and other formats such as SmartSeq2. Other merits include the ability to formalize biological questions into computational models to drive projects forward and provide advice on the experimental design before data generation. The candidate should be self-motivated, have good communication skills, and have a proven ability to interact effectively and work productively in an interdisciplinary team. Fluency in English is a requirement.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Flemingsberg

Choose to work at KI – Ten reasons why

Department of Medicine (MedH) conducts graduate and post-graduate education, as well as research, within a wide range of the medical field, covering all internal medicine specialties, infectious diseases and dermatology. The department consists of seven units with a total of nearly 60 research groups. Our ambition is to be the leading department for medical research and education.

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply at the latest 2023-04-07

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-04-07 at 23:59
Unit: Department of Medicine, Huddinge

Read the job description at the university homepage or apply.

Post expires on Friday April 7th, 2023

Do you want to contribute to improving human health?

Division

The newly started Ketzef laboratory, closely affiliated to the Silberberg laboratory at the Department of Neuroscience, has an open position for a postdoctoral fellow. We are searching for talented and enthusiastic postdocs interested in studying the neural networks of the basal ganglia underlying sensorimotor functions using electrophysiological, optical, and molecular methods.

Duties

The successful candidate should show a high level of responsibility and independency, be able to collaborate with others in a team, and possess good English communication skills. Applicants should have a strong neuroscience background with documented experience in electrophysiology. Experience in surgery, animal behavior, computer programming, and manuscript writing, are highly advantageous. The project will involve in vivo patch-clamp recordings, optogenetics, and imaging in the mouse basal ganglia.

Entry requirements

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Location:

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-04-01 at 23:59
Unit: Silberberg

Read the job description at the university homepage or apply.

Post expires on Saturday April 1st, 2023

Do you want to contribute to top quality medical research?

We are located in a modern research hub called NEO at Karolinska Institutet in Huddinge. You will be working in an international and interdisciplinary research environment, where collaborative efforts are encouraged. We always aim for an open and welcoming environment. Together with other research groups, we offer state-of-the art core facilities providing cell sorting techniques, microscopy, sequencing, mouse facilities, and provide access to clinical samples. This position will be supported by the prestigious Swedish Research Council Starting Grant. The appointment will be for two years with a possible extension for up to two additional years.

Your mission

The failure to regenerate tissue with age is a major health issue. A contributor to this decline is the loss of stem cell function. Despite the essential role of stem cells, it is still unclear how they fail to maintain their functions during aging and disease. We discovered a new aspect of stem cell aging in vivo: cellular enlargement. With age and damage, stem cells increase in size causing their functional decline. However, we are only beginning to understand how size impacts stem cell fitness and the physiological importance of this process remains unsolved.

We are seeking a highly motivated and ambitious individual from universities around the world to join the research team of Assistant Professor Dr. Jette Lengefeld as a Postdoctoral Researcher to mechanistically understand novel mechanisms of human stem cells that drive aging and disease. The Lengefeld research group uses hematopoietic stem cells from mice and human bone marrow donations to discover how deregulation of cellular size is connected to aging and cancer.

Your project will utilize hematopoietic stem cells from elderly or patients with leukemia to identify factors that facilitate stem cell aging and leukemia by single sequencing, creating xenotransplants using “humanized” mice and in vitro systems to investigate the underlying mechanisms

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

Required skills:

• Excellent knowledge in English, written and spoken
• At least one first author publications in recognized peer-reviewed journal
• Good understanding of molecular biology and genetics

Desirable skills:

• A research background in experimental stem cell biology, hematology, sequencing, cell culture and experience working with mice
• Good knowledge of hematopoiesis
• Hands-on experience with cell culture, cell sorting, and advanced flow cytometry
• An attitude to drive own research and work in an intra and inter team fashion
• Soft skills in teamwork, research communication and presentation
• A competence to think logically in biological terms, as demonstrated in research publications
• Expertise in R and foundations of statistics

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Flemingsberg

Lab Webpage

Choose to work at KI – Ten reasons why

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply at the latest 2023-04-02

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-04-02 at 23:59
Unit: Department of Medicine, Huddinge

Read the job description at the university homepage or apply.

Post expires on Sunday April 2nd, 2023

Do you want to contribute to top quality medical research?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

The Smed Sörensen lab is an international research group that does translational immunology on respiratory inflammatory diseases and respiratory viral infections including influenza viruses and SARS-CoV-2. We have attracted funding for our research from the Swedish Research Council, the Swedish Heart and Lung Foundation and the Bill and Melinda Gates Foundation.

The doctoral student project and the duties of the doctoral student

This doctoral research project is focused on using experimental and computational analyses to understand immune responses and disease development in respiratory viral infections. We do longitudinal sampling of respiratory virus infected patients and investigate differences in immune responses over time and across disease severity and relate to clinical outcomes. Patient inclusion and sampling, sample processing, experimental immunological and computational analyses are central duties of the doctoral student in this project. In addition to the doctoral research project, the doctoral student is expected to help with common tasks of the laboratory as well as actively participate in seminars and journal clubs.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

Experience from patient inclusion and sampling is necessary and as a consequence the applicant should hold a medical degree and speak Swedish. Experience from processing human biological samples, biobanking and cell culture is necessary. Experience from experimental immunology is desirable, as is documented research experience in the infection immunology area. Experience in bioinformatics and knowledge in programming (R, python) are desirable. The applicant should hold a master degree in medicine (MD). We are looking for an ambitious, technically skilled and creative person that can communicate in Swedish and English. The successful applicant must be able to work independently within his/her project but also have the capacity to work efficiently and productively in a team. It is necessary to work carefully and systematically.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

–[Video about Karolinska Institutet, how we all work towards “a better health for all”] –

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

Location

The position is located within the Department of Medicine, Solna. The department consists of twelve divisions and each division consists of several research groups. The position is located within the research group of associate professor Anna Smed Sörensen. http://ki.se/en/meds/research-group-anna-smed-sorensen

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-03-21 at 23:59
Unit: Department of Medicine, Solna

Read the job description at the university homepage or apply.

Post expires on Tuesday March 21st, 2023

Do you want to contribute to improving human health?

 The Lindström research group offers a creative and inspiring environment filled with expertise and curiosity. Our vision is to contribute to top quality medical research within our field in order to improve survival and clinical management of breast cancer patients. We are part of the Department of Oncology and Pathology at BioClinicum, which combines basic, translational, and clinical cancer research in an inspiring environment. Karolinska Institutet is one of the world’s leading medical universities and since 1901 the Nobel Assembly at Karolinska Institutet has selected the Nobel laureates in Physiology and Medicine. 

The research group

We are seeking a highly motivated Postdoctoral researcher to join our team who is dedicated to improving the understanding of breast cancer and factors related to survival. Who has a high risk of dying from the disease and why? Breast cancer is a very heterogeneous disease both in tumor biology as well as metastatic capacity and time to fatal disease. For instance, younger women are known to have a worse survival compared to middle-aged women, but the underlying reasons are not well understood. A special interest of the Lindström group is to understand the long-term risk 20-30 years after primary diagnosis since we and others have shown that estrogen receptor (ER)-positive breast cancer patients have a steady and late risk of metastatic and fatal disease. A variety of approaches are used in the Lindström group to answer these research questions, and the group mainly conducts studies by annotating information on tumor characteristics in patient cohorts and clinical studies.

The group has a large network of interdisciplinary collaboration with nationalally and internationalally leading researchers within the field. Linda Lindström is the Co-Director of the Breast Cancer Theme Center (BRECT) at Karolinska Institutet and the Chairman of the national translational breast cancer network Swetribe.

For further information about our work, please consult a selection of reports from our lab:

Lindström LS and Esserman et al, JNCI 2018; Yu and Lindström et al, JAMA Oncol. 2019; Dar H, and Lindström LS. JAMA Netw Open. 2021; Johansson A, and Lindström LS et al. JCO, in press June 2022.

Your mission

We are running several comprehensive and ambitious research studies. In one of these studies, we are continuing our research initiatives on breast cancer intra-tumor heterogeneity which we have shown is associated with more aggressive breast cancer and with a higher risk to die from the disease. In this study we will use several approaches to further understand intra-tumor heterogeneity of breast cancer tumors. One of the projects will focus intra-tumor heterogeneity of the breast cancer markers, the second project on image analysis of tumor slides to assess heterogeneity, and in the third project we will use single-cell sequencing to annotate information on gene expression and DNA mutations on single breast cancer tumor cells. As a foundation of our studies, we have annotated a large clinical randomized trial with genomic information and clinical tumor characteristics including more than 2,500 patients with long-term and high-quality follow-up (20-30 years). The goal of these projects is to understand and predict breast cancer patients’ long-term risk and treatment benefit to improve clinical management and long-term survival.

The Postdoctoral researcher will have the leading role in at least one of the projects and will in that project be responsible for the various parts of the project including planning, literature reviewing, statistical analytical work, data presentation, and scientific article writing.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment.
This must be substantiated by the applicant’s main supervisor, director or equivalent.

We are looking for an enthusiastic and highly motivated candidate with a clear interest in analytical work (biostatistics/ bioinformatics) and breast cancer research including molecular oncology and genomics. Since the Postdoctoral researcher will work and communicate scientific findings in an interdisciplinary and international environment, good communication and writing skills in English are very important.

The applicant should have a mathematical and/or statistical undergraduate education and it is considered an advantage if the applicant also has documented knowledge and experience relevant to the research area such as:

Working with applied data analysis (for example using patient cohorts or registry data) Excellent programming skills in for example R or Python Statistics, including survival analysis and AI/machine learning methods Previous experience in working with image data High throughput genomic analysis Breast cancer Other documented knowledge or experience that may be relevant to the project.

Location: Department of Oncology and Pathology, BioClinicum, Solna

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis.
In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system latest March 20 ^th .

The position is a scholarship for 1 year at Radiumhemmet Research institution. With the possibility of employment at the institution Oncology-Pathology after one year scholarship at Radiumhemmet.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-03-20 at 23:59
Unit: Department of Oncology-Pathology

Read the job description at the university homepage or apply.

Post expires on Monday March 20th, 2023

Do you want to contribute to top quality medical research?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

The Johnson lab offers a stimulating, international research environment. We are part of the Department of Cell and Molecular Biology at the Karolinska Institute in Stockholm, Sweden, one of the world’s leading medical universities. The lab is located in Biomedicum, a state-of-the-art research building on Solna campus. The labs primary focus is on the cellular and tissue response to low oxygen, or hypoxia.

Link to research group page: https://ki.se/en/cmb/randall-johnsons-group

The doctoral student project and the duties of the doctoral student

The project is concerned with the role of hypoxia induced metabolites and their roles in the modulation of T cell responses. The responses that the project will in particular focus on are those related to T cell immunotherapy.

The student will take on an independent project with a focus on a few specific metabolites that our group has found influence both molecular responses in T cells and in particular can alter their epigenetic states during activation following antigen recognition. A characterization of these responses and a better understanding of their mechanistic causes will be the chief focus of the doctoral work.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

The student will need to be highly independent and self-directed. Additionally, the student will need to have good tissue culture training and skills, and extensive experience with molecular biology and immunology techniques, including western blotting, quantitative PCR, and FACs analysis.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2023-03-27 at 23:59
Unit: Department of Cell and Molecular Biology

Read the job description at the university homepage or apply.

Post expires on Monday March 27th, 2023