Subject description

We are recruiting a post-doctoral fellow for 2 years to the ERC-funded project “Hybridization derived novel patterns of gene expression”. This project addresses the role of gene expression in how adaptive variation can arise from hybridization. Two specific questions that will be addressed are 1) to which extent alterations to genomic architecture, including indels and inversions contributes to altered gene expression in a hybrid taxon, the Italian sparrow Passer italiae in comparison to its parental species. 2) the role of altered methylation in altered patterns of gene expression in the hybrid Italian sparrow. To understand which patterns are general, four independent lineages of hybrid Italian sparrows on different Mediterranean islands will be used as a study system. Extraction of long read DNA and de novo assembly of top quality reference genomes from long read data for all these hybrid lineages and annotation will be crucial for achiving these research goals. The post doctoral fellow will perform gene expression analyses, help inform study design and contribute to field work, synthesize and write up the work for publication and work with the HybridExpress team consisting of a lab manager, a PhD-student and a researcher. There will be opportunities for mentorship. The project is led by Associate Senior Lecturer Anna Runemark, and set within the SPeciation, Adaptation and Co-Evolution lab in the biodiversity unit.

Work duties

The main duties involved in a post-doctoral posistion is to conduct research. Teaching may also be included if mutually agreed, but up to no more than 20% of working hours.

Detailed description of the work duties:

• Extraction of long read DNA for long read genomes and RNA for gene expression analysis
• Genome assembly including long read and Hi-C data and annotation
• Identification of structural variation in genomes of the hybrid lineages in comparison to the parent species
• Analysis of methylation
• Analysis of and interpretation of gene expression data
• Synthesizing the data for publication

The position includes the opportunity for three weeks of training in higher education teaching and learning, and the post doc could potentially contribute to the teaching of genome assembly and annotation on the bioinformatics program.

Qualification requirements 

Appointment to a post-doctoral position requires that the applicant has a PhD, or an international degree deemed equivalent to a PhD, within the subject of the position, completed no more than three years before the date of employment decision. Under special circumstances, the doctoral degree can have been completed earlier.

Additional requirements:

• Very good oral and written proficiency in English.
• A documented ability to develop and conduct high quality research.
• Very strong skills in bioinformatics, including genome assembly.
• Documented knowledge of molecular lab work.
• Background and publication record in evolutionary biology, evolutionary ecology or evolutionary genomics

 Assessment criteria and other qualifications

This is a career development position primarily focused on research. The position is intended as an initial step in a career, and the assessment of the applicants will primarily be based on their research qualifications and potential as researchers. Particular emphasis will be placed on research skills within the subject.

For appointments to a post-doctoral position, the following shall form the assessment criteria:

• A good ability to develop and conduct high quality research.
• Strong skills in bioinformatics, including genome assembly from long read data

Additional assessment criteria:

• Documented ability to extract high weight molecular DNA
• Knowledge of development of repeatable workflows such as snake-make

Consideration will also be given to good collaborative skills, drive and independence, and how the applicant’s experience and skills complement and strengthen ongoing research within the department, and how they stand to contribute to its future development.

Terms of employment
This is a full-time, fixed-term employment of a maximum of 2 years. The period of employment is determined in accordance with the agreement “Avtal om tidsbegränsad anställning som postdoktor” (“Agreement on fixed-term employment as a post-doctoral fellow”) between Lund University, SACO-S and OFR/S, dated 1st February 2022.

 Instructions on how to apply

Applications shall be written in English and be compiled into a PDF-file containing:

• résumé/CV, including a list of publications
• a cover letter detailing how your past research experience fits the position and your future research interests (no more than two pages)
• contact information of at least two academic references
• copy of the doctoral degree certificate

Description of the workplace
At the unit of Diagnostic Radiology, research related to clinical image analysis and medical diagnostics is conducted. LUCI (Lund University breast Cancer Imaging) is an interdisciplinary research group within the unit, mainly oriented towards innovative imaging methods of diagnosing breast cancer with a specific focus on screening and artificial intelligence. The units are led by Prof. Sophia Zackrisson, and consists of both researchers and technical staff. More information can be found here.

Intensive research efforts are being made to make way for individualized breast cancer screening. Our group has created a large image data base matched with registry and clinical data about breast cancer cases and as a next step the database will be enriched with tumor genomic information. With the purpose of strengthening the translational focus of the group, we are now looking for a skilled, ambitious, and motivated postdoctoral researcher with competence to work with image-based risk prediction models for breast cancer. The group is located at Skåne University Hospital (SUS) in Malmö.

We care about creating a positive, respectful, and stimulating environment. We value communication and collaboration and a workplace that promotes learning and development for all employees. We are also committed to building a safe and positive environment for all employees through mutual respect and tolerance.

We offer
Lund University is a governmental authority, which means you get special benefits, generous holidays and a favorable occupational pension. We also have a flexible time agreement that creates good conditions for a balance between work and leisure.
Read more on the university’s website about being employed at Lund University, Work with us.

Work duties
The goal of this project is to develop image-based risk prediction models for breast cancer for future individualized screening. You will be responsible for applications, planning and execution of projects for matching data from the SCAN-B registry. Data processing and statistical analysis will be done in cooperation with staff in the research group and statisticians.

The job also includes participating in the daily work of the research group, collecting patient data, helping with supervision of doctoral students and other students, as well as working with producing material for research publications. Other tasks within the research group may become relevant.

Eligibility
Appointment to a post-doctoral position requires that the applicant has a PhD, or an international degree deemed equivalent to a PhD, within the subject of the position. This eligibility requirement needs to be met no later than the time when the employment decision is made, and evidence that this requirement is met needs to have been sent in by this time at the latest. Candidates should have completed their PhD degree no more than three (3) years before the last date for applications. Under special circumstances, the doctoral degree can have been completed earlier. These circumstances refer to leave due to illness, parental leave, clinical work, positions of trust within trade union organizations or other similar circumstances.

Basis for assessment      
At Lund University, employment as a postdoctoral researcher provides opportunities for scientific and pedagogical merit. There is mainly room for merit in research, but also for certain higher education pedagogical training. Teaching may be included in the tasks.

For the employment as a postdoctoral research, scientific ability will primarily be taken into account.

Qualifications
Requirements for the position are:

• A PhD in biomedicine, experimental oncology or biotechnology
• Experience with analysis and data mining to identify trends and produce meaningful data visualizations
• Experience in SPSS or other statistical software
• Experience in writing and communicating scientifically
• Documented oral and written knowledge in English
• Good ability to be proactive and work independently
• Good ability to collaborate with others and be a productive part of a team
• Good communication skills as well as social skills

Meritorious for the position are:

• Experience in breast cancer research, both preclinical and clinical
• Experience with epidemiological methods
• Experience of supervising/teaching students
• Experience of collaborating with international partners

Terms of employment
This is a full-time employment limited to 2 years, with a possible extension for up to one additional year. Preliminary start date 1st of May 2023 or according to agreement. The period of employment is determined in accordance with the agreement “Avtal om tidsbegränsad anställning som postdoktor” (“Agreement on fixed-term employment as a post-doctoral researcher”) between SACO-S, OFR/S and SEKO, dated November 19, 2021.

How to apply
The position is sought via the university’s recruitment system. Applications must include a personal motivation letter, a CV, contact information of two references, a diploma (including a grade transcript) and other documents you wish to be considered.

Description of the workplace

The Laboratory of Epigenetics and Chromatin Dynamics at the Department of Experimental Medical Science (Faculty of Medicine), is currently conducting research investigating the epigenetic regulation of repetitive and transposable genetic elements – so-called ‘genomic dark matter’ – in human brain development. The group consists of 5 research-active members and is led by Dr Christopher Douse. We are fascinated by how these underexplored regions of the human genome contribute functionally to human neurobiology and neurological disease. Our work integrates state-of-the-art wet and dry lab methods. More information can be found at Here. As a workplace, we safeguard a good work environment with respect and consideration in our relationships with each other.

We offer

Lund University is a public authority which means that employees get particular benefits, generous annual leave and an advantageous occupational pension scheme. Read more on the University website about being a Lund University employee Work at Lund University

Work duties and areas of responsibility

You will lead a project on the epigenetic regulation of transposable and repetitive elements by MORC ATPases and associated protein complexes. This will involve designing, executing and analysing loss- and gain-of-function experiments in stem cell models of human brain development. This is a long-term project aimed at discovering new basic human neurobiology, and thereby insights on the mechanistic underpinning of repeat-associated neurological disorders.

Qualifications

Requirements for employment are:

-A masters or equivalent education in molecular biology, biochemistry, genetics or similar topics

-Good, demonstrable knowledge of state-of-the-art methods of epigenome profiling (e.g. CUT&RUN, Nanopore sequencing) and/or methods to model human brain development (e.g. organoids, neural stem cell culture).

-Being a good team-player  with a strong interest in epigenetics and stem cell biology.

-Personal qualities such as curiosity, flexibility and a drive to discover new biology.

Additional qualifications for the position are:

-Excellent interpersonal skills and independence, and an ability and interest in collaborating.

-Experience in handling bioinformatic analyses of genomic methods (e.g. RNA-seq, CUT&RUN-seq)

-Knowledge of basic protein biochemistry (e.g. Western blotting) or imaging (immunofluorescent staining)

-An interest in repetitive and transposable elements.

Further information

The employment is a fixed-term employment for 4 years at 100 percent with a start date 1th of May 2023, or as agreed, but at the latest at 30th of April, 2027.

How to apply

The application should include a personal letter justifying your interest in the position and how it matches your qualifications. The application should also include a CV, degree certificates or equivalent and any other document to which you would like to draw attention (copies of grade transcripts, details of referees, letters of recommendation, etc.) Candidates will be considered on an ongoing basis during the application period.

Eligibility
Students with basic eligibility for third-cycle studies are those who- have completed a second-cycle degree- have completed courses of at least 240 credits, of which at least 60 credits are from second-cycle courses, or- have acquired largely equivalent knowledge in some other way, in Sweden or abroad.

The employment of doctoral students is regulated in the Swedish Code of Statues 1998: 80. Only those who are or have been admitted to PhD-studies may be appointed to doctoral studentships. When an appointment to a doctoral studentship is made, the ability of the student to benefit from PhD-studies shall primarily be taken into account. In addition to devoting themselves to their studies, those appointed to doctoral studentships may be required to work with educational tasks, research and administration, in accordance with specific regulations in the ordinance.

Type of employment
Limit of tenure, four years according to HF 5 kap 7§.

Subject description
New pathways are needed for an efficient alignment of the financial system with the needs of biodiversity. This postdoc links efforts of the research project BIOPATH with aim to assess, co-develop and test existing and novel approaches for integration of biodiversity considerations into financial decision-making with financial actors, and analyse the institutional and policy implications of potential transition pathways. The postdoc will focus on how to develop and adapt life cycle assessment (LCA) methodology to assess biodiversity consequences of alternative use of food, forest products and bioenergy. This requires, in parallel, development of more robust quantitative biodiversity threshold values which can be integrated in financial decision-making by enhanced LCA approaches, similar to the inclusion of quantitative carbon footprint values today. To this end, existing LCA methodologies and biodiversity impact models will be used to develop new and innovative approaches able to integrate biodiversity into financial decision.

Work duties
The main duties involved in a post-doctoral posistion is to conduct research. Teaching may also be included, but up to no more than 20% of working hours. The position shall include the opportunity for three weeks of training in higher education teaching and learning.

The successful candidate will map and evaluate the robustness of existing LCA-based approaches published in various literature which include quantification of biodiversity impacts. In a second step, the candidate will assess the possibilities of integrating enhanced and adapted data-driven biodiversity metrics into developed LCA methodology for different decision contexts. Finally, LCA-based case studies will be performed testing and transforming the approaches mapped in the previous tasks but focusing on biodiversity consequences of alternative uses of bioenergy and food. Here, new biodiversity footprints will be combined with existing carbon footprints utilised in current decision-making, e.g. included in EU and national policy tools.

The work will be carried out with an interdisciplinary project team with expertise in biodiversity and ecological science, environmental systems studies, political science, and more. The postdoc is expected to present results at international conferences, produce high quality scientific papers, and play a role in disseminating the results. Stakeholder interactions are a part of the project. The postdoc is also expected to actively participate in and contribute to the general scientific discussion in the research groups.

Qualification requirements
Appointment to a post-doctoral position requires that the applicant has a PhD, or an international degree deemed equivalent to a PhD, within the subject of the position, completed no more than three years before the date of employment decision. Under special circumstances, the doctoral degree can have been completed earlier.

Additional requirements:

• Very good oral and written proficiency in English.
• Documented skills in life cycle assessments
• Knowledge of ecology and biodiversity mapping
• Demonstrated skills in scientific publishing

Assessment criteria and other qualifications
This is a career development position primarily focused on research. The position is intended as an initial step in a career, and the assessment of the applicants will primarily be based on their research qualifications and potential as researchers.

Particular emphasis will be placed on research skills within the subject.

For appointments to a post-doctoral position, the following shall form the assessment criteria:

• A good ability to develop and conduct high quality research.
• Teaching skills.

Additional assessment criteria:

• Proficiency and experience in life-cycle assessment, in particular related to the use of biomass in different sectors
• Documented knowledge of ecology in general and conservation of biodiversity in particular

Consideration will also be given to good collaborative skills, drive and independence, and how the applicant’s experience and skills complement and strengthen ongoing research within the department, and how they stand to contribute to its future development.

Terms of employment
This is a full-time, fixed-term employment of 2 years. The period of employment is determined in accordance with the agreement “Avtal om tidsbegränsad anställning som postdoktor” (“Agreement on fixed-term employment as a post-doctoral fellow”) between Lund University, SACO-S and OFR/S, dated 1st February 2022.

Instructions on how to apply
Applications shall be written in English and be compiled into a PDF-file containing:

• résumé/CV, including a list of publications,
• a general description of past research and future research interests (no more than three pages),
• contact information of at least two references,
• copy of the doctoral degree certificate, and other certificates/grades that you wish to be considered.

Subject description
Every ecosystem on our planet is composed of a complex community of organisms. The function of these ecosystems is often dependent on interactions – or symbioses – between community members. In the microbial world, symbiotic interactions based on syntrophy (i.e., a type of mutualistic symbiosis where nutrients are exchanged between organisms to allow for metabolic division of labour) are common, especially between prokaryotic organisms in anoxic environments. Such interactions are essential drivers of biogeochemical processes like global carbon, nitrogen, and sulphur cycling. Whether similar roles can be attributed to single-cell eukaryotes (protists) occupying these environments remains unclear owing in large part to our limited understanding of the biology, syntrophic potential, and metabolism of anaerobic eukaryotes.

Work duties
The prospective post-doctoral fellow will be hosted by Dr. Courtney Stairs with support of the European Research Council funded project ‘TANGO2’ in the Biology Department at Lund University. The fellow will develop a genetic methods to study anaerobic respiration in unicellular eukaryotes.  

The work focuses on the development of genetic tools to study adaptation to low-oxygen life styles. Some of the planned methodology include anaerobic culturing, yeast genetics, bioinformatic analysis and experimental evolution of yeast strains. 

The main duties involved in a post-doctoral position is to conduct research. Teaching may also be included, but up to no more than 20% of working hours. The position shall include the opportunity for three weeks of training in higher education teaching and learning.

Work duties include:

• The successful candidate will work on the above outlined research project. It is expected that she/he will apply and optimize methodologies to pursue the overall project goals, and design and interpret experiments. All work will be carried out embedded in a research team, requiring sharing of expertise, open discussion of results and facilitating experiments of other team members. International collaboration is planned in the project, including work visits to at least one foreign lab
• Active participation at international conferences is expected, as well as dissemination of results in peer reviewed international publications
• Opportunities for supervision of degree projects (Bachelor and Master) as well as co-supervision of PhD projects may be provided and would be encouraged
• The successful candidate is expected to actively seek independent research funding during the employment period, to provide an opportunity to transition towards an independent researcher position
• Finally, the position may include limited duties in administration related to the work duties listed above

Qualification requirements 
Appointment to a post-doctoral position requires that the applicant has a PhD, or an international degree deemed equivalent to a PhD, within the subject of the position, completed no more than three years before the date of employment decision. Under special circumstances, the doctoral degree can have been completed earlier. 

Additional requirements:

• Very good oral and written proficiency in English.
• A degree in molecular biology and genetics including unicellular eukaryotes or yeast as a model organisms
• Documented ability in nucleic acid extraction, DNA sequence analysis, cloning, yeast transformation, Southern/northern blot analysis
• Documented experience in bioinformatics and gene and protein database work.
• A good track record of publishing peer-reviewed academic papers
• Evidence of ability to work efficiently both independently and as a member of a team.
• Evidence of ability to organize resources, plan and progress work activities, and meet deadlines effectively and consistently.
• Ability to communicate scientific results and knowledge to non-specialists and students.

Assessment criteria and other qualifications

This is a career development position primarily focused on research. The position is intended as an initial step in a career, and the assessment of the applicants will primarily be based on their research qualifications and potential as researchers. Particular emphasis will be placed on research skills within the subject.

For appointments to a post-doctoral position, the following shall form the assessment criteria:

• A good ability to develop and conduct high quality research.
• Teaching skills. 

Additional assessment criteria:

• Documented abilities and experiences of working with genetic, cell biological and biochemical methods that will be used in the project (see above)
• Documented ability and experience in wet and in silico work with yeast as a model organism
• Documented ability and experience of supervising students, individually and in groups

Consideration will also be given to good collaborative skills, drive and independence, and how the applicant’s experience and skills complement and strengthen ongoing research within the department, and how they stand to contribute to its future development.

Terms of employment
This is a full-time, fixed-term employment of 2 years. The period of employment is determined in accordance with the agreement “Avtal om tidsbegränsad anställning som postdoktor” (“Agreement on fixed-term employment as a post-doctoral fellow”) between Lund University, SACO-S and OFR/S, dated 1st February 2022. Start date: April 16, 2023.

Instructions on how to apply
Applications shall be written in English and be compiled into a PDF-file containing:

• CV (maximum of 2 pages)
• List of publications
• Cover letter (maximum of 2-pages):
  • A general description of your past and future research interests, including methodological knowhow
  • A clear explanation of how your skills can be applied to the enclosed project
  • Contact information of 2-3 references, including previous main supervisors
• Copy of the doctoral degree certificate, and other certificates/grades that you wish to be considered.

Subject description
Every ecosystem on our planet is composed of a complex community of organisms. The function of these ecosystems is often dependent on interactions – or symbioses – between community members. In the microbial world, symbiotic interactions based on syntrophy (i.e., a type of mutualistic symbiosis where nutrients are exchanged between organisms to allow for metabolic division of labour) are common, especially between prokaryotic organisms in anoxic environments. Such interactions are essential drivers of biogeochemical processes like global carbon, nitrogen, and sulphur cycling. Whether similar roles can be attributed to single-cell eukaryotes (protists) occupying these environments remains unclear owing in large part to our limited understanding of the biology, syntrophic potential, and metabolism of anaerobic eukaryotes.

Work duties
The prospective post-doctoral fellow will be hosted by Dr. Courtney Stairs with support of the European Research Council funded project ‘TANGO2’ in the Biology Department at Lund University. The fellow will develop a genetic tool to perform massively parallelized mutagenesis of bacterial symbionts of anaerobic protists to uncover genes essential for symbiotic interactions. These data will be used to approximate metabolic interactions between the organisms.  The candidate will have the potential to develop experimental detection methods to test these predictions in collaborations with Dr. Ryan Gawryluk (U. Victoria, Canada).

The work focuses on the development of genetic tools to study protist:bacteria interactions. Some of the planned methodology include anaerobic culturing, development of genetic tools in Arcobacteracea transposon mutagenesis and bioinformatic analysis. 

The main duties involved in a post-doctoral position is to conduct research. Teaching may also be included, but up to no more than 20% of working hours. The position shall include the opportunity for three weeks of training in higher education teaching and learning.

Work duties include:

• The successful candidate will work on the above outlined research project. It is expected that she/he will apply and optimize methodologies to pursue the overall project goals, and design and interpret experiments. All work will be carried out embedded in a research team, requiring sharing of expertise, open discussion of results and facilitating experiments of other team members. International collaboration is planned in the project, including work visits to at least one foreign lab
• Active participation at international conferences is expected, as well as dissemination of results in peer reviewed international publications
• Opportunities for supervision of degree projects (Bachelor and Master) as well as co-supervision of PhD projects may be provided and would be encouraged
• The successful candidate is expected to actively seek independent research funding during the employment period, to provide an opportunity to transition towards an independent researcher position
• Finally, the position may include limited duties in administration related to the work duties listed above

Qualification requirements 
Appointment to a post-doctoral position requires that the applicant has a PhD, or an international degree deemed equivalent to a PhD, within the subject of the position, completed no more than three years before the date of employment decision. Under special circumstances, the doctoral degree can have been completed earlier. 

Additional requirements:

• Very good oral and written proficiency in English.
• A degree in molecular biology, molecular genetics, molecular cell biology including anaerobic organisms as study material, or similar
• Documented ability in nucleic acid extraction and bacterial transformation and/or development of genetic tools in non-model organisms
• Documented experience in bioinformatics and gene and protein database work.
• A good track record of publishing peer-reviewed academic papers
• Evidence of ability to work efficiently both independently and as a member of a team.
• Evidence of ability to organize resources, plan and progress work activities, and meet deadlines effectively and consistently.
• Ability to communicate scientific results and knowledge to non-specialists and students.

Assessment criteria and other qualifications
This is a career development position primarily focused on research. The position is intended as an initial step in a career, and the assessment of the applicants will primarily be based on their research qualifications and potential as researchers. Particular emphasis will be placed on research skills within the subject.

For appointments to a post-doctoral position, the following shall form the assessment criteria:

• A good ability to develop and conduct high quality research.
• Teaching skills. 

Additional assessment criteria:

• Documented abilities and experiences of working with genetic, cell biological and biochemical methods that will be used in the project (see above)
• Documented ability and experience in wet and in silico work with non-model organisms or environmental microorganisms
• Documented ability and experience of supervising students, individually and in groups

Consideration will also be given to good collaborative skills, drive and independence, and how the applicant’s experience and skills complement and strengthen ongoing research within the department, and how they stand to contribute to its future development.

Terms of employment
This is a full-time, fixed-term employment of 3 years. The period of employment is determined in accordance with the agreement “Avtal om tidsbegränsad anställning som postdoktor” (“Agreement on fixed-term employment as a post-doctoral fellow”) between Lund University, SACO-S and OFR/S, dated 1st February 2022. Preferred start date in May 2023.

Instructions on how to apply
Applications shall be written in English and be compiled into a PDF-file containing:

• CV (maximum of 2 pages)
• List of publications
• Cover letter (maximum of 2 pages): 
  • A general description of your past and future research interests, including methodological knowhow 
  • A clear explanation of how your skills can be applied to the enclosed project
  • Contact information of 2-3 references, including previous main supervisors 
• Copy of the doctoral degree certificate, and other certificates/grades that you wish to be considered.