RETTSGENETIKK ENHET FOR SAKKYNDIGHET OG FORSKNING, Oslo universitetssykehus HF

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PhD candidate or postdoc position available at the Department of Forensic Sciences, Oslo University Hospital (OUS)

There is a fully funded position available for a PhD candidate or postdoc in the Forensic Biology Research Group. We seek an individual with a strong background/degree in statistics/bioinformatics. The position is a three year commitment starting in autumn 2019.

The Section of Forensic Biology at OUS is a caseworking laboratory with about 55 employees. The section performs analysis of biological traces in criminal cases on behalf of the police and judiciary. The research group provides up-to-date and cutting-edge research in an international environment within Forensic Genetics.

DNA-analysis in criminal casework is a powerful forensic tool to link an individual to biological material detected at a crime scene. DNA profiling is the main technique used in criminal investigations, because of its high discriminating power and sensitivity. Over the years, the continuous improvement of this technology has greatly increased the amount of biological data generated, providing new interpretation challenges. This leads to increased requirement to further build statistics/informatics competence in our laboratory. Application deadline: 01/08/2019 Employer: Oslo universitetssykehus HF Title: PhD candidate or postdoc Full-time/part-time: Full-time Employment type: Scholarship Percentage of full-time: 100 Webcruiter ID: 4093041085 Positions: 1 Social sharing :

Areas of research

The PhD candidate/postdoc will join a research team currently working with implementation of algorithms and models based on biological data generated from Massively Parallel Sequencing (MPS) technology (Illumina MiSeq and ThermoFisher Ion S5 System). There are two main areas of research interest which the successful applicant will participate: 

Develop MPS models to integrate with our internationally recognized open source software ‘Euroformix’
         a. Comparative studies with ‘conventional’ methods
         b. Development of MPS nomenclature
         c. Modelling MPS stutters and degradation characteristics
         d. Extend Euroformix in order to take account of the specific characteristics of MPS STR systems
         e. Population genetics aimed towards building an MPS based frequency database

Body fluid prediction using mRNA and microbial patterns, complementing our previous work in this area (https://doi.org/10.1016/j.fsigen.2017.05.009). Here we are interested in expanding our capability to identify body fluids/cell types, using methods like Principle Component Analysis
          a. Expand the capability to different body fluids and tissues
          b. Discover new candidate markers
          c. Study the effect of degradation on mRNA and microbiota
          d. Investigate improved efficiency gains if data from different techniques are combined– specifically mRNA and microbiota from body fluids using existing multiplex systems

Qualifications

• The candidate must fulfil the requirements for a PhD position at the University of Oslo
• The candidate must be able to work as part of a team
• Good communication skills in written and spoken English
• Good computer programming skills (R and C++ are preferred)
• A degree in mathematics, statistics, computer or data science is essential
• Some genetics background is preferable but this should not discourage suitably qualified individuals from applying, since  training will be provided
  

Personal qualities

• Ability to work in a systematic and structured way
• High motivation and enthusiasm for working with research projects
  

We offer

• A welcoming and professionally stimulating international research environment attached to a casework laboratory
• Opportunities for national and international collaboration
• Salary according to current agreements    
  

Location Sognsvannsveien 20, 0372 Oslo, Norway

Contacts

Oskar Hansson

Enhetsleder, oskhan@ous-hf.no

Oslo universitetssykehus er Norges største helseforetak med over 22 000 ansatte. Vi har en rekke nasjonale funksjoner innen spesialisert medisin, og har landets mest avanserte traumemottak.
Vi har stor aktivitet innen forskning, utprøvende behandling, opplæring, utdanning og innovasjon hvor vi er med å utvikle morgendagens medisiner og behandlinger. Oslo universitetssykehus skal være en lærende og skapende organisasjon med et arbeidsmiljø preget av åpenhet og respekt.

Read the job descirption at the university homepage

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Post expires on Thursday August 1st, 2019

Division of Laboratory Medicine, Department of Pathology, Section of Research, Oslo University Hospital

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Research in the Department is currently organized in research groups that integrate university and hospital research activities. Current research topics are within cancer, immunopathology, inflammation and neurodegenerative diseases. The research groups have extensive collaborations with national and international investigators and opportunities to perform translational research are excellent. The successful applicant is expected to strengthen the research activity in the Department.

We have one open PhD research fellow position within the field of bioinformatics or computational biology is available at Oslo University Hospital (OUS) – Norwegian Radium Hospital. The candidate will work at the Department of Pathology at the Norwegian Radium Hospital. The appointment is a full-time position for three years, and is free of any teaching obligations.

Application deadline: 31/05/2019 Employer: Oslo universitetssykehus HF Title: PhD research fellow Employment type: Temp Percentage of full-time: 100 Webcruiter ID: 4047437329 Start date: 03/06/2019
End date: 02/06/2022

Job description

The work tasks will be to design next generation predictive models for detecting functional gene regulation. The new computational method will eventually be applied on high-throughput sequencing data such as genome-wide sequencing data from cancer patients. The project involves both national and international research collaboration. Therefore, the student may spend time in the US with our international collaborator. The candidate will be co-supervised by Prof. Magnar Bjørås from University of Oslo, Dr. Junbai Wang from OUS, and our international collaborator from the US. The scientific work by PhD candidate is expected leading to a PhD thesis at the University of Oslo.

Qualifications

 We seek for a highly motivated person with good knowledge in molecular biology, human genetics, data mining and computational programming. Ideally, the candidate should hold a Master’s degree in bioinformatics or computational biology. However, MSc in physics, computer science or applied mathematics may also be considered if the candidate can show his/her potential in learning molecular biology and human genetics. Please attach a single PDF, which should contain an application letter
stating why you are interested in the position and describing your major achievement in the MSc/BSc works and your key competences, together with a full CV, list of publications if possible, recommendation letters, copies of educational certificates and transcript of records, and detailed contact address (i.e. email and phone number) of three References.

All PhD candidates must show high English language skills. International applicants must document the skills by providing one of the following tests: TOEFL – Test of English as Foreign Language (minimum score 80), IELTS – International English Language Testing Service (minimum score 6.5), PET Academic – Person Test of English Academic (minimum score 62), and CAE – Certificate in Advanced English and CPE – Certificate of Proficiency in English from the University of Cambridge. Applications must be submitted via Webcruiter. Oslo University Hospital distribute offers of employment via email.
Education Level: College / University, Master’s degree.

Language:English, Norwegian  

We can offer

Organized member of one of the best pension plans in Norway

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Read the job description at the university homepage

Oslo University Hospital is a highly specialized hospital in charge of extensive regional and local hospital assignments. As Scandinavia’s largest hospital, we carry out more than 1.2 million patient treatments each year. The hospital has a nationwide responsibility for a number of national and multi-regional assignments, and has several national centers of competence. Oslo University Hospital is responsible for approximately 50 percent of all medical and health care research conducted at Norwegian hospitals, and is a significant role player within the education of a large variety of health care personnel. 

Post expires on Friday May 31st, 2019