Tag-arkiv: malmo university

Post-doc position: Carbohydrate polymers – proteins interactions Malmo

Ref REK2020/29

About Malmö University
Malmö University is an innovative, urban and international institute of higher education, located in the center of Malmö. We have around 1 800 employees and about 25 000 students and thereby one of Sweden’s largest universities. Our research and education are characterized by the role we believe a university should play in an open society, which is to contribute to sustainability and equality in a scientifically grounded way with external partners and stakeholders. Identifying and addressing the challenges of the future are of highest priority. Our researchers and students work in collaboration to create, share and spread knowledge in order to understand, explain and develop society. 

Malmö University is organized into five faculties: Faculty of Health and Society, Culture and Society, Education and Society, Faculty of Odontology and Technology and Society. 

Faculty of Health and Society
Our education and research are conducted with the vision of promoting health and participation. The faculty conducts research that   focuses on societal problems and seeks solutions in several fields of research. We develop leading professional education programs that provide healthcare, social work and enterprises with competent staff. Our education and research are located in three locations in Malmö. 

Biofilms – Research Center for Biointerfaces
The present position will be a part of the research center Biofilms – Research Center for Biointerfaces, which is a large academic environment at Malmö University spanning several departments. The overall objective of Biofilms – Research Center for Biointerfaces is to produce high-quality front-line research within the biomedical field, to offer relevant and attractive educational programs, and to maintain good reciprocal relations with partner industries and the public sector. The center today comprises four research groups (60 researchers) and offers a translational network for applied research, in collaboration with regional industry. The center expertise covers the range from mathematical modelling to clinical sciences. 

About the position
Protein-based therapeutics are becoming increasingly popular in medicine. Compared to low molecular drugs, they are more specific, cause fewer side effects and are environmentally friendly. They are however more sensitive to the conditions of the surroundings and need to be specially formulated to preserve their structure and function. Another challenge in designing protein formulations is to provide slow release of proteins during extended time. In this project we will investigate interactions of proteins with carbohydrate – based drug delivery vehicles: starch microparticles. In the excess of water, proteins partition between starch microparticles and surrounding liquid. We explore different approaches for controlling the release rate of proteins from starch microparticles.

To stabilize proteins in the formulations they can be dried. In the absence of excipients, the proteins can however change their structure, which may influence their stability. In this part of the project, we will perform studies of structure of proteins imbedded in starch microparticles in the solid state. Furthermore, mechanisms of destabilization of proteins in the solid state and the effects of residual moisture will be investigated. The project will be performed in collaboration between Malmö University and two companies: Magle Chemoswed and Adroit Science.

Apart from carrying out research within these areas the applicant is expected to take responsibility for the maintenance of the instruments involved and to be active by supervising graduate and postgraduate students and fellow scientists in the techniques and participate in teaching at graduate and postgraduate levels. In addition, the applicant will be expected to take part in applications for external funding to support research activities.

Qualifications
A postdoc is primarily employed to conduct research. They have completed a doctoral degree or a foreign degree considered on par with a doctoral degree. This is primarily relevant to people who have completed their doctoral degree no less than three years before the application period for the position of postdoc has expired.

Specific requirements for this position
PhD degree in physical chemistry, biochemistry, biophysics, polymer chemistry, physical pharmacy or another relevant discipline

Highly valued requirements for this position:
Hands-on experience in some of the following methods: small- and wide-angle X-ray diffraction/scattering and other scattering techniques, calorimetry and thermal analysis (DSC, ITC, isothermal microcalorimetry, TGA), water sorption techniques, solution or solid-state NMR.

The ideal candidate should also have the ability to work in a team and collaborate with people in complementary disciplines.

Assessment criteria

  • The quality and focus of the doctoral thesis
  • Research activities within fields relevant to the appointment in question
  • Documented ability to independently conduct research of sufficient standard
  • Reflective presentation of their own pedagogical outlook and practices
  • Demonstrated ability to communicate and collaborate with actors in other parts of society with a connection to education and research

For more information contact
Vitaly Kocherbitov, Professor at the Department of Biomedical Science. Phone: +46 40 6657946, E-mail: Vitaly.Kocherbitov@mau.se

Form of employment and starting date
Temporary position for 12 months (full-time) starting from April 1st or as soon as possible thereafter. The position can be prolonged beyond the first year. At Malmö University, individual salary negotiations apply.

Malmö University is a workplace characterized by an open and inclusive approach where equal treatment adds value to our activities.

Application
You apply through Malmö University’s recruitment system by clicking the button “apply/ansök”. You have the responsibility that your application is complete according to the adverted position and your application must be received no later than March 1, 2020.

The application should contain the following:

  1. A brief summary of scientific, teaching and other qualifications relevant to the position
  2. Attested copies of certificates
  3. Curriculum Vitae (CV)
  4. List of scientific publications and developed teaching materials
  5. Copies of three of your most relevant scientific publications
  6. At least two letters of reference

Trade union representatives
SACO-S: Ann-Mari Campbell, ann-mari.campbell@mau.se
Lärarförbundet: Carl-Erik Blomberg, carl-erik.blomberg@mau.se
OFR/S (ST): Naser Eftekharian, naser.eftekharian@mau.se

Welcome with your application!

Read the job description at the university homepage

Apply

Post expires on Sunday March 1st, 2020

Post-doc/Researcher position: Broken Barriers – How to maintain skin health and avoid a defective barrier Malmo

Ref REK2020/20

About Malmö University
Malmö University is an innovative, urban and international institute of higher education, located in the centre of Malmö. We have around 1,800 employees and 24,000 students. Malmö University is organized into five faculties: Faculty of Health and Society, Culture and Society, Education and Society, Faculty of Odontology and Technology and Society. 

The Department of Biomedical Science, Faculty of Health and Society, offers a programme leading to a professional qualification, Biomedical Scientist (first cycle, 180 credits), and a Masters’ programme, Biomedical Surface Science (second cycle, 120 credits), as well as first and second cycle freestanding courses. The Department negotiates the multifaceted intersection between biology, chemistry, medicine, physics, and technology and the interdisciplinary approach to research and education aims to further the theoretical and practical understanding of the complex subject matter. Drawing on the balance between pure and applied research, the Department has been successful in attracting funding from regional, national, and international research funding bodies. 

The research at the faculty is also linked to the research center Biofilms – Research Center for Biointerfaces, which combines biomedical science with clinical and translational research in medical, dental, food and environmental application areas in close collaboration with regional industry.

About the position
The research activities will be conducted in a network of academic, industrial, and clinical partners within a newly funded project entitled Biobarriers – Health, Disorders and Healing. The general vision of the research project is to improve health and healing of biological barriers by modernizing clinical treatments and products based on molecular level knowledge. In particular, the aim of the open position is to investigate how knowledge of molecular and structural characteristics of skin, manipulated by formulations, can be translated into clinical treatments and industrial products for maintaining skin health and preventing deterioration and breaking of the skin barrier.

The outermost layer of the skin organ is called the stratum corneum (SC) and is responsible for the skin barrier, which effectively restricts both inward and outward diffusion of most molecules and thus upholds the water balance and protects us from harmful substances entering the body. The SC is normally exposed to dry and cold climate of the external environment. Therefore, it is perhaps not surprising that the natural moisturizing factor (NMF) is produced spontaneously in the skin barrier. These molecules are known to be beneficial for dry skin and certain skin diseases, such as winter xerosis and atopic dermatitis. We have previously shown that addition of this kind of molecules to the skin alters the molecular mobility of the SC lipid and protein components by retaining the dynamical properties associated with a more hydrated SC membrane at dehydrating conditions. Thus, by retaining the fluidity of the SC components on a molecular level, at reduced hydration conditions, NMF molecules can potentially act to maintain a healthy, soft, and pliable skin barrier.

This hypothesis will be investigated in more detail within this research project by investigating a selection of scientifically and commercially relevant excipients and/or active pharmaceutical ingredients (APIs). The main goal is to clarify the relationship between:

1. the permeability behavior of topically applied excipients/APIs at specified concentrations and characterization of their concentrations in the SC and the basal layer where viable keratinocytes reside,
2. the effect of excipients/APIs on the molecular properties of the SC components (e.g. molecular mobility and structural arrangements of keratin filaments and extracellular lipids), and
3. the effect of excipients/APIs at relevant concentrations (as determined from permeability studies) on cultured keratinocytes.

This relationship is key for understanding what kind of mechanisms that are important for maintaining a healthy skin organ and how to avoid factors and events leading to a defective barrier. With increased understanding of this relationship, it will be possible to explore the beneficial effects of excipients and/or APIs in a scientifically robust manner.

Notably, the work is expected to include both in vitro and in vivo methodology where pig skin is used as in vitro model for human skin, while examination of human skin in vivo is conducted on healthy or diseased human subjects after granted ethical permission; documented writing and approval of ethical permissions is therefore a valued benefit for the applicant. Further, considering that the project requires collaboration between academic, industrial, and clinical partners, it is expected that the applicant actively communicates and collaborate within this context; documented project management and leadership abilities are therefore valued.

Apart from carrying out research within these areas the applicant is expected to take responsibility for the maintenance of the instruments involved and to be active by supervising graduate and postgraduate students and fellow scientists in the techniques and participate in teaching at graduate and postgraduate levels. In addition, the applicant will be expected to take part in applications for external funding to support research activities. 

Qualifications
A postdoc is primarily employed to conduct research. They have completed a doctoral degree or a foreign degree considered on par with a doctoral degree. This is primarily relevant to people who have completed their doctoral degree no less than three years before the application period for the position of postdoc has expired.

Specific requirements
Candidates must hold a PhD in chemistry, chemical engineering, biophysics or a similar field.

Highly valued requirements
The ideal candidate holds a Master’s degree in chemistry, biochemistry or biophysics and has completed a doctoral education focusing on the skin barrier and/or topical or transdermal drug delivery.

Hands-on experience in some of the following methods is highly valued:

  • in vitro permeability studies with Franz cells or similar,
  • in vivo characterization of the skin barrier (e.g. TEWL, corneometry, tape-stripping, electrochemical measurements, etc.),
  • solution or solid-state NMR,
  • small- and wide-angle X-ray diffraction/scattering,
  • HPLC with spectrophotometry and/or mass spectroscopy detection.

 Assessment criteria

  • The quality and focus of the doctoral thesis
  • Research activities within fields relevant to the appointment in question
  • Documented ability to independently conduct research of sufficient standard
  • Reflective presentation of their own pedagogical outlook and practices
  • Demonstrated ability to communicate and collaborate with actors in other parts of society with a connection to education and research

Information
For more information contact Sebastian Björklund, +46 (0)40 6657891, Sebastian.Bjorklund@mau.se

Application
You apply through Malmo Universities’ recruitment system by clicking the button “apply/ansok”. It is your own responsibility that your application is complete with all required documentation according to the adverted position.

Please submit your application no later than March 1, 2020.
The candidate selected for this position must be able to meet eligibility requirements to work in Sweden at  the start of the appointment.

The application should contain the following: 

1. Cover letter with a motivation for applying to this position
2. A brief summary of scientific, teaching, and other qualifications relevant to the position
3. Attested copies of certificates
4. Curriculum Vitae (CV)
5. List of scientific publications and developed teaching materials
6. Copy of doctoral dissertation or equivalent.
7. Copies of three of your most relevant scientific publications
8. At least two references with names, titles/positions, relation to you, and contact information.


Form of employment and starting date
At least one-year position, starting as soon as possible. At Malmö University, individual salary negotiations apply. Full-time 

Starting date 
as soon as possible

Trade union representatives
SACO-S: Ann-Mari Campbell, ann-mari.campbell@mau.se
Lärarförbundet: Carl-Erik Blomberg, carl-erik.blomberg@mau.se
OFR/S (ST): Naser Eftekharian, naser.eftekharian@mau.se

Welcome with your application!

Read the job description at university homepage

Apply

Post expires on Sunday March 1st, 2020

PhD Student Position in Computer Science: the digitalization of higher education Malmo

Ref REK2020/21

Malmö University, located in the center of Malmö, is an innovative, urban, and international institute of higher education, with about 1800 employees and 24000 students. Research and education at the University are characterized by the urgent demands of contemporary society — to contribute to sustainability and equality, based in rigorous science, in close co-operation with external partners and stakeholders, prioritizing and addressing the challenges of the future. Faculty and students work collaboratively to acquire, share, and disseminate knowledge, in order to understand, explain and develop societal circumstances — locally as well as globally.

Faculty
The Faculty of Technology and society (TS) offers education and research in computer science and media technology as well as engineering, sciences and applied mathematics. A characteristic of our research and teaching is the engagement of companies and other organizations as active participants.

Department
At the Department of Computer Science and Media Technology, currently around 60 lecturers, researchers and professors from 20 different countries are employed.

At the department, the research is devoted to the digitalization of our society, and a special area of attention is the Internet of Things, where we mainly investigate the usefulness and human use of the connected devices in our surroundings. Other research areas that our researchers investigate are, e.g., software engineering, intelligent transport systems, and computational media. Apart from a strong cooperation with the industry and with several research organizations, such as the Internet of Things and People Research Center, Software Center, and the Swedish Knowledge Center for Public Transport, our researchers actively take part in research projects with universities around the world.

For more information about the activities at the department, please visit http://mah.se/english/faculties/Faculty-of-Technology-and-Society/

Job description and responsibilities
This PhD student position is directed towards the study and development of methods and technologies intended to support the digitalization of higher education. Special attention will be paid to the concept of privacy, as an integral part of the digitalization of universities is information about individuals. Other crucial concepts include the Internet of Things and Artificial Intelligence, which also drive the development towards the universities of tomorrow. Software and application development are also important parts of the job description for the PhD student.

The PhD student will be part of an interdisciplinary research group launched in order to study the digitalization of higher education institutions and to ensure research-based alignment to the university-wide digitalization initiative at Malmö University. The research of the PhD student will also be connected to the Internet of Things and People research center at Malmö University.

Employment as PhD Student
An employed PhD student shall primarily devote time to his/her own research training. Teaching assignments of up to 20% may be part of your duties. Regulations regarding employment of PhD students can be found in the Higher Education Ordinance 5 Chap. 1-7 §§. The PhD student is expected to actively participate in the research and teaching environment.

The aim of the PhD programme is to develop the knowledge and skills required for the PhD student to independently conduct research and thereby contribute to the development of knowledge within the project. The PhD programmer is worth 240 higher education credits (equivalent to four years of full-time studies).

Eligibility Requirements for Admission
PhD students are both employed at the University and admitted to the study programme in parallel.

To be eligible for PhD studies, a student must have:

1. a second-cycle higher education degree.
2. completed course requirements of at least 240 higher education credits, of which at least 60 higher education credits are second-cycle.
3. in some other way, nationally or internationally, acquired equivalent knowledge. 

Regulations regarding admission to PhD studies can be found in Higher Education Ordinance 7 Chap. 34-41 §§.

Specific Admission Requirements
Specific eligibility is accorded to those who have knowledge and skills equivalent to a second-cycle degree in computer science or in another subject that has relevance for computer science.
Excellent knowledge of written and spoken English is a prerequisite.

Assessment and Selection Criteria
Initial assessment concerns the general and specific eligibility requirements (above).
Furthermore, according to the Higher Education Ordinance 5 Chap. 5 §, importance is placed on the student’s ability to appropriate the advanced learning of the third-cycle PhD programme. The previously written material and the dissertation plan are important indicators of this ability as well as research experience and documented relevant working life experience. Of special relevance are independently written material on advanced level (MSc).

Good knowledge (on the level of second-cycle higher education degree) of computer science or related area, knowledge in data management, software development, sensor technology, and machine learning is meritorious.

Knowledge and ability to participate in contexts where the Swedish language is spoken is also meritourious.

Additional assessment criteria include demonstrated analytical and communication skills, and demonstrated fluency in written and spoken English.

Information
Andreas Jacobsson, dean, chair at the council for digitalization, andreas.jacobsson@mau.se
Bo Peterson, head of department, bo.peterson@mau.se
Sara Eriksson, HR specialist, sara.eriksson@mau.se

Instructions for Application
You apply through Malmö University’s recruitment system by clicking the button “Apply/Ansök” below. You have the responsibility that your application is completed with all required documentation according to the adverted position. Your application must have arrived no later than 2020-02-23.
The candidate selected for this position must be able to meet eligibility requirements to work in Sweden at the start of the appointment

The application should contain the following documents (when applicable):

1. A personal letter in which the applicant gives a short description of him/herself and his/her research interests in relation to the position. (max 2 pages)
2. CV
3. Complete list of publications and creative works relevant to the position (including scholarly as well as general-interest publications, advanced level independent thesis and reports).
3. Master’s thesis or similar degree projects
4. Copies of writings that you specifically wish to highlight (maximum 3 writings)
5. Certificates and university transcripts, certifying your CV
6. References (at least 2; names, titles, contact information positions/relation.
Please do not submit letters of reference).

Form of Employment
Employment is full-time and time restricted according to Higher Education Ordinance 5 Chap. 7 §.

Malmö University is characterized by an open and inclusive approach, where gender equality and equal opportunities add value to our activities.

Starting Date
As soon as possible

Union Representatives
SACO, Stefan Gustafsson, stefan.gustafsson@mau.se
ST/OFR Bodil Sterner, bodil.sterner@mau.se
PhD Student Union representative, johan.salo@mau.se

Welcome with your application!

Read the job description at the university homepage

Apply

Post expires on Sunday February 23rd, 2020