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Postdoctoral researcher in eating disorders with expertise in epidemiology



Mental Health Center Ballerup seeks a postdoctoral researcher to join a strong international research environment in eating disorders, starting from March 2023 or soon thereafter. The position will be offered between 80-100% FTE, depending on seniority.  
 

The position

You will contribute to a large grant on risk and resilience for the development of eating disorders across development, mostly focusing on adolescents and young adults. You will have diverse tasks and responsibilities, incl. conceiving research ideas, developing study protocols, data analysis, writing manuscripts etc. in collaboration with both in-house, national and international collaborators. There will be opportunities for you to develop new research questions.

The project will rely on Danish register data and large population-based cohorts (e.g., ALSPAC, UK Biobank).

You will join a dynamic and growing team and work across the Eating Disorders Research Unit and the Institute of Biological Psychiatry.

As well as benefitting from this large collaborative grant, you will benefit from an existing large network of collaborations both within Denmark and abroad.

In this position you will supervise junior colleagues (PhD students, research assistants, interns, etc.). and report to the Head of the Eating Disorders Unit.
 

Environment

The Center for Eating and feeding Disorders Research-CEDaR) is a multicultural and multidisciplinary team recently set up with a large portfolio of grants, across epidemiological, genetic, neuroimaging, and clinical intervention studies in feeding and eating disorders. We are a dynamic, collaborative, and international team, that is rapidly growing. The unit has several international collaborations with the UK, US, Sweden, Germany, Switzerland.

Research in eating disorders is a highly prioritized research area of the Mental Health Services in the Capital Region of Denmark. We have a strong commitment to perform research at the highest international level with the aim of providing new insights into what causes eating disorders and better treatments for patients.
 

Qualifications

  • You are highly motivated to drive and pursue research in eating disorders.
  • You have a PhD in epidemiology or public health, or epidemiology applied to behavioural data. It is desirable but not necessary to have experience in obesity or eating disorders research.
  • You are an enthusiastic researcher, with experience in designing and carrying out research in psychiatric epidemiology.
  • You have proven skills in effective project management and co-ordination.
  • You have excellent oral and written communication skills in English
  • You have experience in working on Danish registers (desirable).

You must demonstrate original academic production in the field of psychiatric epidemiology, as evidenced by peer reviewed publications in English. 

Participation in international networks and collaboration with researchers and key institutions within eating disorders or epidemiology is an advantage.
 

Conditions:

Salary, pension and other conditions of employment are set in accordance with the Agreement between the Ministry of Finance and AC (Danish Confederation of Professional Associations) or other relevant organisations.

The position is in accordance with best Danish labour practices, including a 37-hour work week, six weeks of paid vacation per annum, funded parental leave, matched pension contributions, enrolment in national healthcare, and labour union representation.

The position is funded by a 7-year Laureate award from the Novo Nordisk Foundation (NNF) grant to Prof Micali, and  initially offered for a fixed-term of two years with the possibility of an extension to five years.

Non-Danish applicants may be eligible for tax reductions if they hold a PhD degree and have not lived in Denmark in the last 10 years.


Application procedure

The position is open for appointment until the 30th March. Rolling interviews will be held as applications are reviewed. The position is available at the earliest convenience. 

Applications – including the required attachments – must be sent via the link provided. Only online applications will be accepted. Applications must be written in English.

The application must contain:

  • a motivation letter
  • a detailed CV
  • degree certificates
  • a complete and numbered list of publications
  • two references

References will be obtained for the applicant who is the first choice for the position. The application will be evaluated by an assessment committee.

If you are interested in the position but want to know more or are unsure about your CV fitting the position contact the Head of the Eating Disorders Unit Prof. Nadia Micali, email: nadia.micali@regionh.dk PA and Unit administrator Kate Livemore, kate.livemore@regionh.dk.
 

Do you want to know more about us?

Since 2017, treatment of all adult patients with Eating Disorders in the Capital region has been located at Mental Health Centre Ballerup, and around one thousand patients are referred for treatment each year, making it one of the largest clinics for Eating Disorders in Europe.

Mental Health Center Ballerup is a part of Copenhagen University Hospital and one of nine departments, that provide treatment for mental disorders in the Capital Region of Denmark. The department consists of ten inpatient wards comprising 157 beds, nine outpatient clinics with several specialized functions and three research groups. We employ around 90 medical doctors and 80 psychologists in addition to nurses, physiotherapists, occupational therapists, social workers, and technical and administrative staff.

Facts

Job type

Forsker, Postdoc

Workplace

Region Hovedstadens Psykiatri

Work hours

Full Time

Job number

247995

Application due

30-03-2023

Contact us

Nadia Micali
E-mail

Read the job description at the university homepage

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Apply

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Post expires on Thursday March 30th, 2023

PhD fellowship at the Neurobiology Research Unit, Rigshospitalet and University of Copenhagen: “Good Vibes”

A 3-year PhD fellowship is available at the Neurobiology Research Unit (NRU) at Rigshospitalet and University of Copenhagen (UCPH), Denmark, with an anticipated start on May 1st 2023, or soon thereafter.

The stipend is funded by the InnovationFond Denmark and the EU Joint Programme Neurodegenerative Disease Research (JPND2022-120) and is a collaborative project on Augmenting glymphatic transport with monitored vibrations to prevent Alzheimer’s disease (aka “Good Vibes”).

About Good Vibes

Our consortium consists of the following frontline academic partners:

  • University of Oulu, Finland (Coordinator)
  • University of Copenhagen, Center for Translational Neuromedicine, Denmark 
  • Copenhagen University Hospital Rigshospitalet, Neurobiology Research Unit, Denmark 
  • Stichting Radboud University, Nijmegen, the Netherlands
  • Semmelweiss University, Budapest, Hungary

The consortium research builds on the recent observations that failure of the glymphatic system, as observed in rodents, leads to impaired brain solute transport which is linked to neurovascular changes that contribute to Alzheimer’s Disease. Imaging of brain fluid transport has in recent years gained international attention due to its role clearing waste products, such as beta-amyloid and tau. Glymphatic transport is most dominant during sleep offering new insight into the neurobiology underlying the necessity to sleep identified in all species studied so far.

The focus of the consortium is to target mechanisms that can prevent AD by augmenting the pulsatile perivascular cerebrospinal fluid solute efflux from the brain. The major aim is to understand how physical oscillations can be used to improve glymphatic hydrodynamics and waste efflux.

About your project

Your project will involve research in pigs where you will conduct ultrafast functional neuroimaging with MREG which currently is the only approach that non-invasively can detect physiological pulsations simultaneously over the whole brain. Invasive tracer studies in rodent have indicated that the hydrodynamic brain pulsations reflect the glymphatic CSF fluid transport in the lissencephalic brain. We aim to quantitatively investigate to what extent this occurs in the more gyrencephalic pig as a larger animal model with which NRU has extensive experience. The pig is an ideal translational model for glymphatic function and we want to cross-compare brain MREG pulsations in pig brain with traditional approaches to map glymphatic flow in rodents. We want to compare 3T MREG pulsation mappings in pigs with gold-standard cisterna magna tracer injection using multimodal neuroimaging approaches. The gold-standard approach includes real-time SPECT scanning with a high-resolution camera after infusion of 99mTc-DTPA in cisterna magna of the anesthetized pig. To validate this, we will also impose physiological or pharmacological modulations on the brain pulsations to alter CSF hydrodynamics. The effects of the manipulation on MREG pulsatility spectra in the pig brain will be monitored and compared with glymphatic fluid transport in the same brain, also using the other neuroimaging approaches.

Eligibility criteria

We are looking for a dedicated and skilled individual with the following qualifications:

– Obtained a Master’s degree, preferably within neuroscience, life sciences, medicine or engineering. To be considered for the position, it is a condition that your Master’s degree is considered to be equivalent to a Danish Master’s degree.

– Passed course in Laboratory Animal Science EU Function ABD (formerly FELASA Category C), or willingness to undergo the course at the earliest convenience.

– Fluency in English.

The candidate will be enrolled at the Faculty of Health and Medicines at the University of Copenhagen. The graduate program requires the student to obtain 30 ECTS points during the three-year period in order to graduate. A broad set of PhD courses are offered (https://phdcourses.ku.dk/). The school offers financial support for a stay abroad. Subscription to the PhD program is anticipated to be completed over the first 3 months of the employment, where the successful applicant will be employed as a research assistant. You are expected to spend up to 3 months at one of the collaborating institutions.

About NRU

Neurobiology Research Unit (NRU), the Neuroscience Center, Rigshospitalet, is a research center with approximately 125 scientists focusing on conducting translational neuroscience research on brain neurotransmission with the aim to promote preventive, diagnostic and therapeutic advances. We make use of in vivo molecular, structural, and functional brain imaging (PET and MRI) combined with genetic and biochemical approaches and behavioral assessments to uncover disease mechanisms and risk correlates as well as to determine drug effects. We also make use of animal and cell models as well as human brain tissue to investigate drug effects and diagnostic value in the clinic. We identify biomarkers and mechanisms behind neurobiological and psychiatric disorders and develop new treatment or prevention strategies. We bring discoveries from cells and animals into healthy volunteers and patients with brain disorders as early as possible.

NRU collaborates with many national and international research institutes and is partner in and houses the management of the Lundbeck Foundation funded project BrainDrugs. NRU wishes our staff to reflect the diversity of society and thus welcomes applications from all qualified candidates regardless of personal background.

Terms of employment

Employment will start May 1st 2023, or soon thereafter.

The terms of employment and salary are in accordance with the agreement between Danish Regions and The Danish Confederation of Professional Associations on Academics in the Regions.

More information

More information about NRU can be found at https://nru.dk/.

For further information about the position, applicants may contact Professor Gitte Moos Knudsen (phone: +45 3545 6720; email: gitte.knudsen@nru.dk) or Senior Group Leader Hanne D. Hansen (phone: +45 3545 6718; email: hdh@nru.dk).

Application

The application must include a cover letter, a curriculum vitae, a list of peer reviewed publications, as well as possible letters of recommendation and diplomas.

The closing date for applications will be March 25, 2023.

Facts

Job type

PhD

Workplace

Rigshospitalet – Blegdamsvej

Work hours

37 timer

Job number

247986

Application due

25-03-2023

Contact us

Gitte Moos Knudsen
Professor
E-mail

Read the job description at the university homepage

Apply

​​​

Post expires on Sunday March 26th, 2023

Two-year Postdoc Position in Clinical Omics Data Integration

This is an opportunity to join the Systems Medicine Research Group at Steno Diabetes Center Copenhagen (SDCC).

About the Systems Medicine Research Group
The Systems Medicine research group is headed by a research manager and currently involves ten scientists. We lead and are partners in consortia focusing on the development of type 1 and type 2 diabetes, and diabetic complications in brain, liver, and gut metabolism. We specialize in the human metabolome, lipidome and proteome to design tests for clinical decision-making (personalized medicine) and to discover novel mechanisms to target in disease. 

About the Project
Position is divided into two steps, where in the first year you will support ongoing projects within metabolomics data processing and multiomics integration. Last two years will be dedicated to diabetes complication, namely neuropathy, where we aim to set up a standardized data analysis for clinical application and personalized medicine through development of a new software. Joining our group, you will become a central part of research project, where we will focus on biomarkers development for prediction of distal symmetrical polyneuropathy in type 1 diabetes. Through this translational project you will be able to influence real-life diagnostics applied to patients at Steno Diabetes Center.

The Position
You are expected to lead and contribute to dissemination of results. You will work with a quality mindset for creating reproducible research for the benefit of the patient. You will be able to supervise and manage projects. You will take responsibility in maintaining and developing pipelines for high-throughput data analysis.
We are looking for a candidate with:

  • Expertise in omics data integration and programming in R and/or Python 
  • Proven record of lead-author publications in the field of genomics, metabolomics, or proteomics
  • Experience in developing and publishing computational tools to analyze data in clinical science
  • PhD in biochemistry, chemistry, bioinformatics, computational biology, data science or another relevant field
  • Knowledge of Neo4j platform is highly appreciated  


What we offer
We offer a career path that promotes taking a key role in clinical research projects. We have close interaction with clinicians for patient-related research and an international network with industry and academia for collaborative opportunities. 
There will be opportunity to supervise, apply for funding, to develop managing skills and to define and lead multiomics projects. 

Recruitment and employment
As part of the recruitment procedure the candidate’s qualifications will be assessed by an academic assessment committee. The employment is in accordance with the Capital Regions collective agreements.

Contact and Information
Applications for the position are accepted online before 31st of March 2023. Interviews are expected to be held in week 16 with starting date of employment of the 1st of June 2023 or soon after. For further information about the position, please feel free to contact senior researcher Karolina Sulek or head of the group Cristina Legido Quigley on +45 3091 3393. We welcome applications from all candidates with the relevant professional background and qualifications. We reserve the right to close this vacancy early if we receive highly qualified applicant for the position. Therefore, if you are interested, please submit your application as early as possible.

About Steno Diabetes Center Copenhagen 
Steno Diabetes Center Copenhagen (SDCC) is specialized in patient care, research, prevention of diabetes, and in education of health care professionals within diabetes. SDCC is the largest diabetes clinic in Scandinavia, treating annually more than 11,000 children and adults with diabetes.
 

Facts

Job type

Postdoc

Workplace

Steno Diabetes Center Copenhagen

Work hours

37

Job number

246931

Application due

31-03-2023

Contact us

Cristina Legido Quigley
E-mail

Read the job description at the university homepage

Apply

Post expires on Friday March 31st, 2023