Tag-arkiv: University of Oulu

Doctoral student, Biochemistry and Structural Biology

The University of Oulu is one of the largest universities in Finland, with approximately 15 000 students and 3 000 employees. We, at the University of Oulu, work as part of the international science community to produce new scientific information and science-based solutions. Our university’s several specialized research and service units enable extensive and diverse development and career opportunities for experts in various fields.

Protein and Structural biology is one of he three research focus areas of the Faculty of Biochemistry and Molecular Medicine. The Faculty provides a dynamic research surrounding and cutting-edge research infrastructure services to academics and other users in Finland and abroad. The Faculty has about 190 employees (including PhD students) of which about half are from outside of Finland.

The host research team also belongs to Biocenter Oulu (http://www.oulu.fi/biocenter/), which offers a high-level international multidisciplinary environment supplied with cutting-edge infrastructures.  Under this framework, the Health and Biosciences Doctoral Program offers doctoral training in clinical medicine, biomedicine, biochemistry, molecular medicine, dentistry, health sciences, medical technology. For more information: http://www.oulu.fi/uniogs/dp/hbsdp

We have now an opening for a fixed-term, full-time Doctoral student position in research project headed by Professor Lari Lehtiö in the Protein and Structural Biology research unit, Faculty of Biochemistry and Molecular Medicine.  The position is supervised by professor Lehtiö and is focused on structural and functional characterization of human tankyrases as well as in development of small molecule inhibitors as tools and as potential future drug leads.

Our team focuses on structure, function and selective inhibition of proteins involved in signaling through ADP-ribosylation – a post translational modification affecting protein stability, function and interactions in multiple cellular pathways.  We use X-ray crystallography, small angle X-ray scattering, cryoEM and other biophysical techniques to study the structure and function of these, often multidomain proteins, work. We develop assays suitable for high-throughput screening of inhibitors and use structural information for more rational design to develop specific inhibitors that can be used as chemical probes to study the functions of the proteins and in some cases to validate them as drug targets. Protein X-ray crystallography is our main tool used to understand structure-activity relationships of compounds. For more information, please see web pages: https://www.oulu.fi/university/focusarea/lifelong-health/spearhead-projects/lehtio and twitter: https://twitter.com/lablehtio

Requirements

To successfully occupy the position of a doctoral student, the candidate must possess a Master’s degree or an equivalent degree (e.g. licentiate) preferably in biochemistry. Degree must have been completed with good grades by 28.2.2021.

The doctoral student position is intended for an Early Stage Researcher (ESR) who is defined as a researcher in the first four years (full-time equivalent) of his/her research activity, including the period of research training. Applicants will be either starting their doctoral training or will have completed no more than two full years of training (adjusted for possible previous part-time status) at the time the position is filled. The selected candidate will carry out his/her doctoral studies in the Health and Biosciences Doctoral Program of the University of Oulu Graduate School (UniOGS) and must meet the minimal requirements to receive doctoral study rights as defined in http://www.oulu.fi/uniogs/requirements_for_admission.

Salary

The salary of selected doctoral students will be initially set on level 2, and later on levels 2 – 4 of the national salary scale for the teaching and research staff of Finnish universities. In addition, a supplementary remuneration is given for personal achievement and performance (max. 50 %). In practice, the salary is roughly 2200 – 3000 € per month for an early stage researcher, depending on the appointee’s qualifications and progress of the doctoral thesis.

The position is filled for a maximum of four-year period. The employment begins on 1 March 2021 or as soon as possible thereafter. A six-month trial period is applied in the positions.

Application

Applications must be submitted using the electronic application form by January 20th, 2021 (23:59Finnish local time, EET), with the following attachments as three separate pdf files:

  1. Complete CV containing contact information of at least two referees (Max. size limit of the attachment: 5 Mbytes)
  2. Motivation letter (maximum 1 page) describing prior knowledge and research interests and career plans (1-2 pages; max. size limit of the attachment: 2 Mbytes).
  3. Certificates/Diplomas: Scanned electronic copies of diplomas and transcripts of the records of relevant previous degrees. If the original documents are not in English, Finnish or Swedish, each document must be accompanied by an official certified translation into English or Finnish. (Max. size limit of the attachment: 2 Mbytes)

Other relevant information

The eligible applicants fitting best in the research profile expected for the position may be invited to an on-site or remote interview. All applicants will be notified when the selection process is completed.

For further information:

Professor Lari Lehtiö, e-mail: lari.lehtio (at) oulu.fi

Apply for the job

Read the job description at the university homepage

Post expires on Wednesday January 20th, 2021

DOCTORAL STUDENT FOR INTELLIGENT MOBILITY AND LOGISTICS

The University of Oulu is one of the biggest universities in Finland. We are a multidisciplinary international science and innovation community working in close cooperation with our peer institutes, industry, and the public sector. Together we form a globally significant innovation hub, pushing the boundaries of knowledge for a more sustainable and intelligent future.

We are now looking for a

DOCTORAL STUDENT FOR INTELLIGENT MOBILITY AND LOGISTICS

to join the Faculty of Technology at the University of Oulu. The position is based in Structures and Construction Technology Research Unit and the research team of Infrastructure & Transport.

The duties and tasks of the Doctoral Student will be associated with a 4-year European research project AURORAL (Architecture for Unified Regional and Open digital ecosystems for Rural Areas Large scale applications). Specifically, there will be concrete project tasks related to project work packages and dissemination activities (website, newsletters, etc.). The Doctoral Student will also be expected to complete studies and research aiming for a degree of Doctor of Science (Technology) within the Doctoral Programme of Civil Engineering. Studies and research for the doctoral degree include research data collection, analysis of data and publishing the results in peer-reviewed journals. Other duties include teaching undergraduate courses (approx. 5 % of the 1612 annual working time) and other projects.

To succeed in the position the candidate is required to have good basic knowledge of the field and a completed MSc degree (transport engineering, industrial engineering, computer or information sciences, business or economics, or similar). The project tasks require adequate skills in website design and hosting as well as being active in developing those skills. The candidate must have a proficient command of both written and spoken English. The candidate is expected to contribute to the work of other project team members, and therefore teamwork and collaboration skills are essential. The candidate can expect good support for his/her own work from the surrounding team and will be able to contribute to teaching activities depending on the candidate’s motivation and capabilities.

We appreciate the following characteristics for the prospective candidate:

  • Curiosity and willingness to explore challenges of digitalized transport and mobility
  • Open-minded and proactive attitude in teamwork
  • Commitment to achieve ambitious project objectives
  • Goal-orientation in candidate’s own doctoral studies

We offer an exciting opportunity to contribute to the development of digital ecosystems of mobility and to develop one’s own academic career. Furthermore, the University of Oulu offers opportunities of a big organisation, flexible working hours, excellent work-life balance, salary payments for 12 months / year, leave corresponding to a holiday and extensive occupational healthcare services. The line manager will be the research unit head. For a well-performing and academically-oriented candidate, the university offers exciting career opportunities.

The salary will be based on the levels 2 – 4 (2 200 EUR/month – 3 100 €/month) of the demand level chart for teaching and research staff of Finnish universities. The level will be decided according to applicant’s qualifications and experience. In addition, a salary component based on personal work performance will be paid (maximum of 50 % of the job-specific component).

Applications and further information

Applications, together with all relevant enclosures, should be submitted using the electronic application form by Monday, January 18, 2021 at 23:59 (Finnish local time). Please include the following attachments in PDF form in your application:

The position is filled as of February 1, 2021 (or as soon as possible after this date). A trial period of six (6) months is applied in the position.


Further details are available from:

Veikko Pekkala, University Teacher, veikko.pekkala(at)oulu.fi, +358 50 354 7352 and
Virve Merisalo, University Teacher, virve.merisalo(at)oulu.fi, +358 50 436 2260

Apply for the job

Read the job description at the university homepage

Post expires on Monday February 1st, 2021