Tag-arkiv: University of Helsinki

Postdoc­toral Re­searcher / Doc­toral Stu­dent in Food Pack­aging

The department of Food and Nutrition is a collaborator in an EU funded project “Healthy Food Africa”, and the project PI is University lecturer Hanna Koivula. Food packaging is a multidisciplinary research topic, requiring knowledge in material and food sciences, where the results can improve the wellbeing of both the people and the planet. We are now looking to strengthen the food packaging research team and are therefore seeking for

POSTDOCTORAL RESEARCHER / DOCTORAL STUDENT IN FOOD PACKAGING

for a fixed-term 1 year contract (depending on the level of the position and starting date) to work in the “Healthy Food Africa” project. The starting date is 1.12.2020 but can be negotiated. The position is funded initially for one year with a possibility for extension depending on availability of additional research funding (applicants will be expected to apply for further funding together with the project PI). There will be a trial period of six months in the beginning.

The project focuses in increasing the efficiency of agri-food chains and improving food safety through the development of innovative post-harvest innovations, packaging, new technologies and the minimization of food waste. Sustainability, collaboration and communication across the food value chain are the core of the project.

We are looking for a highly motivated and skilled researcher with preferably a PhD or MSc degree in food sciences, chemical engineering, physical chemistry, or other related fields. The postdoctoral researcher or doctoral student are expected to contribute to research on in Healthy Food Africa project, in analysis and creation of increased value and sustainability in food systems through improved processing and packaging. The appointed researcher will work in collaboration with the project colleagues at University of Helsinki and other members of the Healthy Food Africa project under supervision of D.Sc. (Tech), University lecturer Hanna Koivula.

Doctoral student: The appointee should either already have the right to pursue a doctoral degree at the University of Helsinki by the start of the appointment, or apply for the right and obtain it within the probationary period of six months of their appointment. If the candidate does not already have the right to pursue a doctoral degree at the University of Helsinki, it must be applied for separately. https://www.helsinki.fi/en/research/doctoral-education/the-application-p…

For a postdoctoral researcher, the salary of the successful candidate will be based on level 5 – 6 of the demands level chart for teaching and research personnel in the salary system of Finnish universities. In addition, the appointee will be paid a salary component based on personal performance. The starting salary will be ca. 3300 – 3800 euros/month, depending on the appointee’s qualifications and experience.
The salary for the doctoral candidate position is based on levels 2–4 of the job requirement scheme for teaching and research personnel in the salary system of Finnish universities. In addition, the appointee will be paid a salary component based on personal work performance. Depending on the appointee’s qualifications and experience, the salary is ca EUR 2200–3050 per month (starting salary EUR 2200-2400).

A successful candidate should be able to:
• Coordinate, evaluate and conduct research on food preservation, food-packaging interactions and technological solutions, and report research.
• Communicate, effectively project partners with multidisciplinary background.
• Contribute to proposal writing to apply further research funding.
• Contribute to master/doctoral student supervision and teaching of food science.
• Engage with scientific community, research partners and the wider public at all levels, internationally and domestically through scientific publications as well as for example through social media (blogs, etc.).

The candidate is expected to have:
Education, experience and technical skills
• A degree in an applicable field and experience in materials sciences/technologies (a doctoral degree for the postdoctoral researcher position or a master’s degree for the doctoral student position).
• Knowledge of physicochemical methods and practices used to characterize and evaluate food packaging functionality and safety is an advantage.
• Fluency in English and excellent writing and communication skills.

Personal attributes and competencies:
• Excellent analytical and research skills
• Innovative in research planning
• Has capability and willingness to study broadly around his/her expertise
• Excellent interpersonal and communication skills and is experienced in working within multicultural and multidisciplinary teams.
• Has high motivation for academic research, takes initiative and is capable of working both independently as well as in team.
• Values continuous improvement based on constructive evaluation, self-reflection and learning.

HOW TO APPLY
Applicants are requested to enclose with their applications the following documents. Please compile all documents as a single pdf file.
For both positions:
1) A curriculum vitae, clearly indicating type and level of qualifications.
2) A list of publications (postdoctoral applicants should indicate three most important publications to be considered for the position).
3) A statement (max 1 page) explaining the applicant’s motivation to apply for the position and how his/her expertise would productively contribute to research on intergenerational effects in criminology.
4) Names and contact details of people possibly providing references.
Additionally, for the position of postdoctoral researcher:
5) A summary (max. 2 pages) of the applicant’s scholarly activities including: summary of previous original research, academic networks and collaboration, disciplinary and interdisciplinary activities, success in obtaining research funding, and other relevant details.

Please submit your application through the University of Helsinki Recruitment System via the link Apply for the position. Applicants who are employees of the University of Helsinki must submit their application via the SAP HR portal, saphr.it.helsinki.fi. The deadline for applications is 12 of October, 2020.

For more information, please contact Dr Hanna Koivula: hanna.koivula(at)helsinki.fi.

Due date

12.10.2020 23:59 EEST

Read the job description at the university homepage

Apply for the position

Post expires on Monday October 12th, 2020

Doc­toral Stu­dent / Research As­sist­ant in mi­to­chon­drial biology and sig­nalling

The University of Helsinki as research-oriented university offers a stimulating and international environment. The Faculty of Medicine of the University of Helsinki, together with Helsinki University Central Hospital, The Helsinki Institute of Life Science, and the Institute for Molecular Medicine Finland forms the Academic Medical Center Helsinki. This medical campus ranks among the 10 best medical centers at European level and the 50 best centers in the world. More info on the Faculty or Medicine and AMCH can be found here:

https://www.helsinki.fi/en/faculty-of-medicinehttps://www.helsinki.fi/en/meilahti-campus

Faculty of Medicine, Jackson laboratory, invites applications for a position of
Doctoral Student / Research Assistant in mitochondrial biology and signalling
for a fixed-term

The focus of the lab is to unravel fundamental signalling pathways and mechanisms controlling mitochondrial function. We are particularly interested in how mitochondria adapt signalling to metabolic cues in models of dysfunction including primary mitochondrial patient cell lines, cancer and associated disorders. We aim to exploit this knowledge on basic principles of mitochondrial signalling and subsequent metabolic susceptibilities in cellular models to help devise novel treatments of diseases that stem from misregulated mitochondrial function.

In this role the candidate will have the unique opportunity to drive an exciting project addressing limiting metabolic pathways in models of mitochondrial dysfunction by genome-wide CRISPR screening and mitochondrial structural analysis. The successful candidate will have access to a wide range of methodologies with work consisting in preparation of cell models, construction of libraries, and analysis of metabolic, proteomic and microscopic data at the cellular level.

We are looking for a highly motivated independent researcher with prime analytical skills driven by a passion for science. We expect you to formulate your own hypotheses, propose experimental design to address them, and take advantage of the laboratory and research community’s intellectual and skill resources to advance the knowledge of the field. The appointee is expected to publish in top-level international peer reviewed scientific journals. In addition, she/he is also expected to potentially take part on the other research tasks such as ones related to ongoing studies and preparation of grant applications. The specific responsibilities will vary according to the level of expertise of the candidate.

The ideal candidate has an extensive background in standard molecular cell biological methods, ideally encompassing genetic and microscopic techniques and/or bioinformatics (NGS data). Expertise in biochemistry and molecular biology is a pre-requisite for this position. Additional expertise for research projects involving human subjects, primary cell culture would be highly desirable. The ideal candidate is an adaptable team-player and has excellent communication and organizational skills and a strong command in written and spoken English and should be familiar with the constraints related to translational research.

This position will provide multiple opportunities for collaborations with potential lab visits abroad and cross-disciplinary scientific exchange, where the candidate will receive extensive training in cutting-edge technology. An aptitude to drive and maintain intra and inter team collaborations will be highly appreciated. In return, the candidate is offered access to an extensive variety of methodology and advanced techniques, appropriate supervision and help in career development.

More information about the lab, including the latest research and news, can be found here:
http://www.jacksonlab.org

The DL for applications has been extended, all applications will be taken into consideration.

The position is initially limited to 2 years with a possibility of extension starting from September 2020. The contract of employment includes a probationary period of 6 months. Salary will be based on the Universities salary scheme for teaching and research personnel composed of both task specific and personal performance components.

The position will remain open until a suitable candidate will be recruited.

Please submit: CV, list of publications, motivation letter including a description of your research interests, and the names and telephone numbers of at least two referees.

Please submit your application, together with the required attachments, through the University of Helsinki electronic recruitment system by clicking on the ‘Apply for job’ button. Internal applicants (i.e., current employees of the University of Helsinki) submit their applications through the SAP HR portal.

For further information, please contact Christopher B. Jackson, Ph.D., docent:
christopher.jackson(at)helsinki.fi

Due date

30.09.2020 23:59 EEST

Read the job description at the unviersity hompage

Apply for the position

Post expires on Wednesday September 30th, 2020

Com­pu­ta­tional bio­lo­gist / Bioin­form­atician in the field of func­tional ge­n­om­ics and cancer research

Computational biologist / Bioinformatician in the field of functional genomics and cancer research (available immediately)

We are seeking a highly motivated and talented individual for working in the field of functional epigenomics in cancer research and transcriptional regulation. The focus of the lab is to investigate the interplay between transcription factors and oncogenes using modern genome-wide methods for regulatory genomic features and chromatin architecture. The group belongs to the Applied Tumor Genomics Program in the Research Programs Unit of the Faculty of Medicine at the University of Helsinki providing an excellent research environment with strong focus on cancer research. The center is very well equipped with modern facilities and supported with core facilities for genomics, next generation sequencing, proteomics, imaging etc. We offer a position in an ambitious, multi-disciplinary and well-resourced group that is comprised of both wet-lab and computational scientists (https://www.helsinki.fi/en/researchgroups/enhancer-biology).

The candidate should have a PhD / Master’s degree in any field of computer science, bioinformatics or life sciences with expertise in computational data analysis and strong motivation towards biomedical research. Prior experience in analysis of high-throughput genome-wide omics datasets from next-generation sequencing methods is desirable. Candidates should have a strong background in programming languages (Perl, Python, R etc.) and ones with proven track record in terms of publications will be given preference. A good understanding of biochemistry, genomics experiments and bioinformatics is expected. The ideal candidates will be involved in computational analysis and integration of functional genomics datasets such as ATAC-seq, Hi-C, ChIP-seq, single-cell genomics as well as genome-wide CRISPR-based approaches.

With English as a working language, excellent oral and written communication skills are required.

Salaries are based on the salary system for Finnish universities (YPJ) in the range of 40,000 – 45,000 euros per annum for post-docs and 25,000 – 28,000 euros for PhD students depending on experience level, and a six-month trial period will be applied.

Details on the project and other informal queries are very welcome and should be sent to biswajyoti.sahu(at)helsinki.fi.

Applications will be considered on a rolling basis till a suitable candidate is found.

Applications should be in a form of single pdf containing (1) a one-page cover letter describing your research goals, interest and motivation, (2) a recent curriculum vitae (CV) including publications, and (3) two–three reference letters with contact details of the referees.

Please apply as soon as possible or by October 8, 2020 via the University of Helsinki electronic recruitment system (by clicking on “Apply for job”). Internal applicants (i.e., current employees of the University of Helsinki) must submit their applications through the SAP HR portal.

The Faculty of Medicine promotes scientific research of a high standard and is responsible for providing research-based undergraduate and postgraduate education in medicine, dentistry, psychology and logopedics, as well as for the English-language Master’s Programme in Translational Medicine. In addition to its teaching and research activities, the Faculty serves as a significant expert organisation in the healthcare sector and contributes to the discourse on ethics in the field. In terms of research, the Faculty aims for a place among the best medical faculties in the world, while consolidating and strengthening its status as a top-level institution of medical education.

Together with the Helsinki University Hospital (HUS) and the Helsinki Institute of Life Sciences (HiLIFE), the Faculty of Medicine, University of Helsinki, constitutes the Academic Medical Center Helsinki (AMCH). This medical center has been very successful in international comparisons, ranking among the top 10 medical campuses in Europe and among the top 50 globally.

Due date

08.10.2020 23:59 EEST

Read the job description at the university homepage

Apply ofr the position

Post expires on Thursday October 8th, 2020

PhD or Post-doc­toral re­search­ers in sys­tems- and cog­nit­ive neuroscience

The University of Helsinki, founded in 1640, is one of the world’s leading universities for multidisciplinary research. The university has an international academic community of 40,000 students and staff members.
Neuroscience Center in the Helsinki Institute of Life Science (HILIFE) is an independent research organization. Research in Neuroscience Center spans scales from molecular and cellular neuroscience to developmental, cognitive, and systems neuroscience.

The Palva group has a longstanding interest in the comprehensive understanding of systems-level neuronal basis of cognition. Specifically, the research is centered in resolving large-scale architecture of oscillatory brain dynamics and its functional significance in cognition and behavior in humans and recently also in mice models.

The research groups of Satu Palva at the Neuroscience Center, HiLIFE invites applications for

1-2 PHD or POSTDOCTORAL RESEARCHER

The PhD or postdoctoral researchers will participate in Academy of Finland funded project “Systems-level neuronal basis of short-term memory and working memory”. The objective of the researcher is to carry out research on large-scale neuronal oscillations and connectomics using magnetoencephalography (MEG) in association with computational modelling and TMS.
We are looking for enthusiastic, innovative, and strongly motivated postdoctoral researcher or PhD with prior experience to join our multidisciplinary research team.

The position is available for 2 + 1 years starting January 2021.

PhD or Postdoctoral applicants should possess MSc or PhD degree, respectively, in a relevant field (engineering, cognitive neuroscience, computer science, neurophysiology or similar). We expect prior experience in MEG, EEG or in vivo electrophysiology, neuronal oscillations and good signal processing and programming skills. Prior experience in connectomics, computational modelling and TMS is considered an advantage. Post-doctoral researcher should have a proven academic track-record in these fields with publications in international scientific journals. The position require also good communication skills with written and spoken English.

This position will provide multiple opportunities for collaborations with potential lab visits abroad and cross-disciplinary scientific exchange. Candidate is offered access to a wide variety of methodologies and advanced techniques, appropriate supervision and help in career development.

The salary of the successful candidate will be determined by the demands level chart for teaching and research personnel in the salary system for Finnish universities. In addition, the appointee will be paid a salary component based on personal performance. The starting salary is about 2200 – 3200 euros/month for the PhD researcher and 3200 – 3800 euros/month for the postdoctoral researcher, depending on the appointee’s qualifications and experience. A six-month trial period will be applied.

Application should include the following documents as a single pdf file: (1) a motivation letter, (2) a CV and publication list, and (3) the names and email addresses of two persons capable of providing a recommendation for the applicant.

To apply, please submit the application through the University of Helsinki electronic recruitment system by clicking on Apply for job. Internal applicants (i.e., current employees of the University of Helsinki) please submit your applications through the SAP HR portal.

Deadline for application is 31.10.2020, but review of applications will begin immediately and continue until the position is filled.

Informal enquiries should be sent to satu.palva(at)helsinki.fi.

For questions regarding the recruitment process, please contact HR Specialist Anu Roine (anu.roine(at)helsinki.fi). Technical support regarding the recruitment system: rekrytointi@helsinki.fi.

For an outline of the group’s research:

https://www.helsinki.fi/en/helsinki-institute-of-life-science/units/neur…

http://criticaloscillations.org.index.html

Due date

31.10.2020 23:59 EET

Read the job description at the university homepage

Apply for the position

Post expires on Saturday October 31st, 2020

Post-doc­toral fel­low / PhD stu­dent in the field of func­tional ge­n­om­ics and cancer research

Post-doctoral fellow / PhD student in the field of functional genomics and cancer research (available immediately)

We are seeking a highly motivated and talented individual for working in the field of functional epigenomics in cancer research and transcriptional regulation.

The focus of the lab is to investigate the interplay between transcription factors and oncogenes using modern genome-wide methods for regulatory genomic features and chromatin architecture.

The group belongs to the Applied Tumor Genomics Program in the Research Programs Unit of the Faculty of Medicine at the University of Helsinki providing an excellent research environment with strong focus on cancer research. The center is very well equipped with modern facilities and supported with core facilities for genomics, next generation sequencing, proteomics, imaging etc. We offer a position in an ambitious, multi-disciplinary and well-resourced group that is comprised of both wet-lab and computational scientists
(https://www.helsinki.fi/en/researchgroups/enhancer-biology).

The candidate should have a PhD / Master’s degree in any field of life sciences or quantitative sciences with a particular interest in functional genomics and cancer research. The ideal candidates will be involved in generation and integration of functional genomics datasets from next-generation sequencing methods such as ATAC-seq, Hi-C, ChIP-seq, single-cell genomics as well as CRISPR-based approaches.

A good understanding of cell and molecular biology, biochemistry, genomics experiments and bioinformatics is expected. Prior experience in generation and analysis of high-throughput omics datasets is desirable and candidates with proven track record in terms of publications will be given preference, especially for postdoctoral fellows. With English as a working language, excellent oral and written communication skills are required.

Salaries are based on the salary system for Finnish universities (YPJ) in the range of 40,000 – 45,000 euros per annum for post-docs and 25,000 – 28,000 euros for PhD students depending on experience level, and a six-month trial period will be applied.

Details on the project and other informal queries are very welcome and should be sent to biswajyoti.sahu(at)helsinki.fi. Applications will be considered on a rolling basis till a suitable candidate is found.

Applications should be in a form of single pdf containing (1) a one-page cover letter describing your research goals, interest and motivation, (2) a recent curriculum vitae (CV) including publications, and (3) two–three reference letters with contact details of the referees.

Please apply as soon as possible or by October 8, 2020 via the University of Helsinki electronic recruitment system (by clicking on “Apply for job”). Internal applicants (i.e., current employees of the University of Helsinki) must submit their applications through the SAP HR portal.

The Faculty of Medicine promotes scientific research of a high standard and is responsible for providing research-based undergraduate and postgraduate education in medicine, dentistry, psychology and logopedics, as well as for the English-language Master’s Programme in Translational Medicine. In addition to its teaching and research activities, the Faculty serves as a significant expert organisation in the healthcare sector and contributes to the discourse on ethics in the field. In terms of research, the Faculty aims for a place among the best medical faculties in the world, while consolidating and strengthening its status as a top-level institution of medical education.

Together with the Helsinki University Hospital (HUS) and the Helsinki Institute of Life Sciences (HiLIFE), the Faculty of Medicine, University of Helsinki, constitutes the Academic Medical Center Helsinki (AMCH). This medical center has been very successful in international comparisons, ranking among the top 10 medical campuses in Europe and among the top 50 globally.

Due date

08.10.2020 23:59 EEST

Read the job description at the university homepage

Apply for the position

Post expires on Thursday October 8th, 2020

Postdoc­toral Re­searcher in Biological Net­work Mod­el­ling

A postdoctoral position is available at the Faculty of Medicine, University of Helsinki, Finland to work in the research group of Dr. Jing Tang (https://www.helsinki.fi/en/researchgroups/network-pharmacology-for-preci…). The position is part of an Academy of Finland’s research project that aims to do network pharmacology modeling to provide the mechanism of action of drugs and drug combinations for a systems-level understanding of cancer. The Tang group combines computational methods to offer improved efficiency methods to identify more effective cancer treatments for personalized medicine. The Tang laboratory is based at Research Program in Systems Oncology (ONCOSYS) (https://www.helsinki.fi/en/researchgroups/research-program-in-systems-on…) at the Meilahti biomedical campus.

Role description:
We are seeking at least one postdoctoral researcher to work on the computational methods to develop network pharmacology models for predicting drug combinations. The project is focused on strategies for predicting potential drug combination and patient subclasses by constructing multipartite networks using drug response data. The primary goal of the project is to analyse drug sensitivity datasets to exploit drug-target interaction data to explore the biological mechanism of drugs. A key aim of the work is to propose drug combination regimens focusing on patient-derived drug response data along with the providing a biochemical and biophysical understanding of a drug combination. Hematological malignances and ovarian cancer are the available datasets for this project. The post holder will be responsible for planning and conducting computational research within the project under the supervision of Dr. Mohieddin Jafari, and Prof. Jing Tang.

The ability to work well within a collaborative team is critical for this position. You will work with unique datasets derived from large-scale experiments associated with a diverse range of projects in pharmacology and molecular biology. Salary will be commensurate with qualifications and experience based on the University guidelines. The full-time position start Jan 2021. A six-month trial period will be applied.

Key requirements:
We are seeking a creative and highly motivated individual with primary interest in network science and biomedical data mining. Candidates should have a PhD in bioinformatics, computational biology, statistics, computer science or other related disciplines. The ideal candidate will have experience in at least one of the aforementioned areas, and a strong interest in the others. Previous experience with biological networks, omics datasets, and expertise in related statistics and modelling are considered an advantage. Solid skills in scripting/programming (preferably R and Python) are essential prerequisites for this position. Excellent communication and presentation skills in English, good organisational skills, troubleshooting expertise and the ability to work effectively to tight deadlines are desirable.

Appointment details:
The position is available from October 2020 onwards, and can be started later upon agreement. It is a two-year fixed-term position, with a possibility of extension. Trial period of 6 months will be applied. The salary will be based on level 5 of the demands level chart for teaching and research personnel in the salary system of Finnish universities. In addition, the appointee will be paid a salary component based on personal performance with the overall starting salary amounting to approximately 3300-3600 EUR per month, depending on the qualifications and previous relevant research experience of the candidate.

Application details:
Please submit your application via the University of Helsinki Recruitment System by clicking the ‘Apply for the position button’ below. Internal applicants (i.e. current employees of the University of Helsinki) should submit their applications through the SAP HR portal. If you need support with the recruitment system, please contact recruitment@helsinki.fi.

Please attach the following documents to your application as a single PDF file:
– CV (including publications)
– Cover letter (maximum 1 page) that details your past experience and motivation for applying to the post.
– At least two recommendation letters with the contact details

The deadline for applications is September 30th 2020. Interviews will be conducted either in person or online. For more information on the position, please contact Dr. Mohieddin Jafari (mohieddin.jafari(at)helsinki.fi) and Prof. Jing Tang (jing.tang(at)helsinki.fi).

The University of Helsinki (UH), founded in 1640, is a vibrant scientific community of 40,000 students and researchers. It is one of the leading multidisciplinary research universities and ranks among the top 100 international universities in the world. It is currently investing heavily in life sciences research. UH offers comprehensive services to its employees, including occupational health care and health insurance, sports facilities, and opportunities for professional development.

Together with the Helsinki University Hospital (HUS) and the Helsinki Institute of Life Sciences (HiLIFE), the Faculty of Medicine, University of Helsinki, constitutes the Academic Medical Center Helsinki (AMCH). This medical center has been very successful in international comparisons, ranking among the top 10 medical campuses in Europe and among the top 50 globally.

Research Program in Systems Oncology (ONCOSYS) consists of basic, translational and clinical researchers who use cutting-edge measurement technology, patient data and AI methods in cancer research and oncology. The overall objective of ONCOSYS is to understand the underlying causes of cancer progression or treatment resistance, and to develop effective diagnostic, prognostic and therapeutic approaches.

Due date

30.09.2020 23:59 EEST

Read the job description at the university homepage

Apply for the position

Post expires on Wednesday September 30th, 2020

Postdoc­toral Fel­low in Com­pu­ta­tional On­co­logy

Join the Systems Biology of Drug Resistance in Cancer research group (https://www.helsinki.fi/en/researchgroups/systems-biology-of-drug-resist…) in University of Helsinki, Finland as

POSTDOCTORAL FELLOW IN COMPUTATIONAL ONCOLOGY

to discover combination therapies to overcome chemotherapy resistance in ovarian cancer. We have collected one of the largest high-quality data set that consists of WGS, bulk RNA-seq, whole-genome DNA methylation, ctDNA, single-cell RNA-seq or single-cell proteomics data from >1000 samples taken from 200 patients before and after chemotherapy within pan-Europe HERCULES (https://project-hercules.eu/) project. Complete and curated clinical data offers various data mining and integration opportunities in addition to the sequencing data. Our network enables validation of computational results and as well as translation of the validated results to clinic.

We expect:
• Strong methodological expertise. For example, in fields of statistics, applied mathematics, engineering or bioinformatics.
• Demonstrated track record of research experience in relevant subject areas, such as multivariate data analysis, machine learning, or mathematical modelling.
• Ability to both conduct research independently and work in collaborative multidisciplinary projects
• Good knowledge of English, both written and spoken
• Basic understanding of cancer biology is considered as an advantage

We offer:
• Excellent data, mentoring and infrastructure to conduct science at the highest level.
• A postdoctoral position for 3 years with a possibility for extension.
• A salary based on experience. Starting salary for a recently graduated postdoc is approx. 3500€
• an international multidisciplinary research environment with state-of-the-art facilities and computational resources
• occupational health services, flexible working hours, and excellent sports facilities, among other benefits of working for the biggest and highest ranking university in Finland

Work environment
The Systems Biology of Drug Resistance in Cancer research group is part of the cross-disciplinary Systems Oncology research program (https://www.helsinki.fi/en/researchgroups/research-program-in-systems-on…) at the Faculty of Medicine in University of Helsinki, Finland. The medical center ranks at the top 10 medical campuses in Europe and among the top 50 globally.

Application
Apply at latest on 30.9.2020. Application should include a short cover letter describing your areas of expertise and motivation, CV and list of publications. The application, together with the required attachments, must be submitted through the University of Helsinki electronic recruitment system by clicking on ‘Apply for the position’ link. Internal applicants must submit their applications through the SAP HR portal.

Further information is available from the group leader, professor Sampsa Hautaniemi, sampsa.hautaniemi(at)helsinki.fi, Tel. +358 50 336 4765.

The University of Helsinki (UH), founded in 1640, is a vibrant scientific community of 40,000 students and researchers. It is one of the leading multidisciplinary research universities and ranks among the top 100 international universities in the world. It is currently investing heavily in life sciences research. UH offers comprehensive services to its employees, including occupational health care and health insurance, sports facilities, and opportunities for professional development.

Together with the Helsinki University Hospital (HUS) and the Helsinki Institute of Life Sciences (HiLIFE), the Faculty of Medicine, University of Helsinki, constitutes the Academic Medical Center Helsinki (AMCH). This medical center has been very successful in international comparisons, ranking among the top 10 medical campuses in Europe and among the top 50 globally.

Due date

30.09.2020 23:59 EEST

Read the job description at the university homepage

Apply for the position

Post expires on Wednesday September 30th, 2020

Epidemiologist, FIMM

The University of Helsinki is an international scientific community of 40,000 students and researchers. It is one of the leading multidisciplinary research universities and ranks among the top 100 international universities in the world.

The Institute for Molecular Medicine Finland (FIMM) is an international research unit focusing
on human genomics and personalised medicine at the Helsinki Institute of Life Science (HiLIFE) of the University of Helsinki – a leading Nordic university with a strong commitment to life science research. As part of Academic Medical Center Helsinki in Meilahti campus FIMM collaborates locally with the Faculty of Medicine, Helsinki University Hospital and National Institute for Health and Welfare. FIMM is part of the Nordic EMBL Partnership for Molecular Medicine, composed of the European Molecular Biology Laboratory (EMBL) and the centres for molecular medicine in Norway, Sweden and Denmark, and the EU-LIFE Community.

FIMM is currently seeking
Epidemiologist

FIMM is the leading genetics and precision medicine research unit in Finland. We are managing petabytes of human genetics and health data, and these datasets will likely increase tenfold in the forthcoming years. We are daily collaborating with top researchers and research institutes in the world and international health-care companies to improve health and well-being on a global scale. FIMM is seeking an experienced epidemiologist to have a key role in the expansion of one of the largest research projects in Finland.

The FinnGen research project (https://www.finngen.fi/en) led by the University of Helsinki, aims to better understand the mechanisms of disease by combining genomic and health information. FinnGen is one of the very first personalised medicine projects at this scale, and the public-private collaborative nature of the project is exceptional compared to many ongoing studies. The project brings together Finnish universities, hospitals and hospital districts, THL, Blood Service, biobanks and international pharmaceutical companies. The FinnGen study utilizes samples collected by Finnish biobanks and the goal is to better understand how our genome affects our health by involving 500,000 Finns. The FinnGen project is prepared to launch a new effort that aims to recontact up to 200,000 participants to collect detailed information about health status and lifestyle.

Qualification and requirements: We are looking for an experienced epidemiologist that will take a leading role in the Finngen recontacting study. Tasks include setting up and analyzing questionnaires data, evaluating participation rate, and employ strategies to improve it. The candidate will work closely with the Finnish Biobanks and the FinnGen partners to implement changes in the study protocol. He/She will also be responsible for identifying and implementing tools for reporting aggregate questionnaire results. Because of the highly collaborative nature of this job, effective verbal and written communication skills are required. The candidate should have at least 5 years of experience in working with survey or epidemiological data and good knowledge of statistical programming languages such as R or Stata. A doctoral degree and a publication track record are considered a plus. The candidate will closely work with The Data Science and Genetic Epidemiology Lab (https://www.dsgelab.org/) led by Dr. Andrea Ganna.

Contract & salary: The job is for a fixed-term of an initial 1 year with a possibility to extend it for three years. A trial period of 6 month will be applied. The starting salary will be ca. 3500 – 4300 euros/month, depending on the appointee’s qualifications and experience and including a salary component based on personal performance. Standard Finnish pension benefits and occupational health care are provided for University employees.

Finland is a member of the EU, has high quality free schooling (also in English), generous family benefits and healthcare, and was recently ranked as the best country in the world for expat families and in the world’s top ten most livable cities. Finland and the Helsinki region possess top expertise in sciences in terms of a vibrant talent pool, leading research, strong support services and functioning collaboration networks. For more information about working at the University of Helsinki and living in Finland, please see https://www.helsinki.fi/en/university/working-at-the-university

How to apply: The application should include (i) CV, (II) a one- page statement of motivation for applying for this position, (iii) contact information of at least one reference persons who have agreed to provide a written statement on behalf of the applicant and (iv) a publication list, if any.

To apply, please submit the application through the University of Helsinki electronic recruitment system by clicking on Apply for job. Internal applicants (i.e., current employees of the University of Helsinki) please submit your applications through the SAP HR portal. Please apply no later than 30 September 2020.

For further information about the position, please visit https://www.finngen.fi/en or contact Andrea Ganna (aganna@broadinstitute.org). For more information about our working environment visit https://www.helsinki.fi/en/hilife-fimm and https://www.dsgelab.org/. For questions regarding the recruitment process, please contact HR Specialist Anu Roine (anu.roine@helsinki.fi). Technical support regarding the recruitment system: rekrytointi@helsinki.fi.

Due date

30.09.2020 23:59 EEST

Read the job description at the university homepage

Apply for the position

Post expires on Wednesday September 30th, 2020

Postdoctoral Researcher in Statistical Human Genetics

The University of Helsinki is an international scientific community of 40,000 students and researchers. It is one of the leading multidisciplinary research universities and ranks among the top 100 international universities in the world.

The Institute for Molecular Medicine Finland (FIMM) is an international research unit focusing
on human genomics and personalised medicine at the Helsinki Institute of Life Science (HiLIFE) of the University of Helsinki – a leading Nordic university with a strong commitment to life science research. As part of Academic Medical Center Helsinki in Meilahti campus FIMM collaborates locally with the Faculty of Medicine, Helsinki University Hospital and National Institute for Health and Welfare. FIMM is part of the Nordic EMBL Partnership for Molecular Medicine, composed of the European Molecular Biology Laboratory (EMBL) and the centres for molecular medicine in Norway, Sweden and Denmark, and the EU-LIFE Community.

FIMM is currently seeking

Postdoctoral Researcher in Statistical Human Genetics

The Data Science and Genetic Epidemiology Lab (https://www.dsgelab.org/) lead by Dr. Andrea Ganna is interested in the development or application of methods to translate genetic discovery efforts into public health-relevant measures. In our group, we integrate electronic health records with genetic information from large biobank-based studies (e.g. https://www.finngen.fi/en). Our team includes experts in human genetics, epidemiology, and machine learning and we have recently launched the COVID19 Host Genetic Initiative (https://www.covid19hg.org/), to study the genetic determinants of COVID19 severity.

Our lab is based at FIMM and at Massachussets General Hospital/Harvard Medical School and affilitated with the Broad Institute. The candidate would be able to work periodically in both locations, if necessary. FIMM also provides excellent training opportunities for postdoctoral researchers through the FIMMPOD postdoctoral program.

Qualification and requirements: We are looking for future research leaders to work with an unprecedented amount of health information (diagnoses, medications, socio/demographic information, etc.) from millions of individuals in combination with biobank-based genetic data. The candidate will develop and pilot cutting edge approaches that leverage this data to elucidate the biological basis of disease and translate these findings into relevant public-health intervention. The successful candidate should prove a solid understanding of statistical genetics methods, including genome-wide association studies, Mendelian randomization, polygenic scores, and family-based designs. Understanding of epidemiological design and measures is considered a plus.

The candidate should hold a Ph.D. in the field of genetics, statistics, mathematics, computational sciences or genetic epidemiology. The ideal candidate shows scientific independence, has publishing experience, and an aptitude towards developing novel techniques. Together with the PI, he/she is jointly responsible for coordinating projects and supervising PhD students.

Contract & salary:. The job is for a fixed-term of 2 years with a possibility of extension for additional two years. A trial period of 6 months will be applied. The starting salary will be ca. 3300 – 3800 euros/month, depending on the appointee’s qualifications and experience and including a salary component based on personal performance. Standard Finnish pension benefits and occupational health care are provided for University employees.

Finland is a member of the EU, has high quality free schooling (also in English), generous family benefits and healthcare, and was recently ranked as the best country in the world for expat families and in the world’s top ten most livable cities. Finland and the Helsinki region possess top expertise in sciences in terms of a vibrant talent pool, leading research, strong support services and functioning collaboration networks. For more information about working at the University of Helsinki and living in Finland, please see https://www.helsinki.fi/en/university/working-at-the-university.

Given the current COVID19 pandemic we will also consider candidates that want to work mostly remotely.

How to apply: The application should include (i) CV, (ii) a publication list, (iii) a one- page statement of research interests and motivation for applying for this position and (iv) contact information of at least two reference persons who have agreed to provide a written statement on behalf of the applicant.

To apply, please submit the application through the University of Helsinki electronic recruitment system by clicking on Apply for job. Internal applicants (i.e., current employees of the University of Helsinki) please submit your applications through the SAP HR portal. Please apply no later than 30 September 2020.

For further information about the position, please visit our website at https://www.dsgelab.org/ or visit https://www.helsinki.fi/en/hilife-fimm or contact Andrea Ganna (aganna@broadinstitute.org). For questions regarding the recruitment process, please contact HR Specialist Anu Roine (anu.roine@helsinki.fi). Technical support regarding the recruitment system: rekrytointi@helsinki.fi.

Due date

30.09.2020 23:59 EEST

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Post expires on Wednesday September 30th, 2020

Doctoral student student in molecular biology/ transcriptional regulation

The University of Helsinki is a research-oriented university, which offers stimulating and international working environment. The Faculty of Medicine of the University of Helsinki, together with Helsinki University Central Hospital, The Helsinki Institute of Life Science, and the Institute for Molecular Medicine Finland forms the Academic Medical Center Helsinki. This medical campus ranks among the 10 best medical centers at European level.

DOCTORAL STUDENT IN MOLECULAR BIOLOGY or TRANSCRIPTIONAL REGULATION
The tentative starting date for the position is 1st of January 2021.

Dr. Harri Itkonen is setting up a new research group at the Department of Biochemistry and Developmental Biology, Faculty of Medicine, University of Helsinki, and is looking for a highly motivated doctoral student to join his team.

The group of Harri Itkonen is looking for outstanding candidates for a PhD Student trainee position to study how metabolism is integrated to regulate global gene expression. We utilize a wide range of techniques including cell biology, organoid technology, live-cell imaging, mass spectrometry, ChIP- and RNA-seq among others to study processes that cancer cells are addicted to (see eg. Itkonen and al. Mol Cancer Res 2020; Itkonen and al. Theranostics 2019; Martin and al. J Am Chem Soc. 2018). The aim of the current project is to understand how the crosstalk between RNA polymerase II modifying enzymes regulates global gene expression.

We are looking a creative thinker with strong analytical skills and high motivation to develop novel therapies to treat cancer. Our group is well connected internationally, and the hired PhD Student will have a chance to present her / his findings in international conferences, and the training includes a tentative half a year research visit to University of Oxford.

The PhD Student candidate must hold, or soon receive, an MSc degree, and have background in molecular biology and / or bioinformatics. The ability to independent thinking and interest in computational biology will be prioritized. Strong written and oral communication skills in English are a must. Experience in one of the following methodologies: cell culture, RNA biology, ChIP- / RNA-sequencing is expected. Candidates are requested to familiarize themselves with the literature, and informal inquiries about the position prior to deadline are encouraged to harri.itkonen(at)helsinki.fi.

The appointee must apply and obtain the right to pursue a doctoral degree at the University of Helsinki within the probationary period of 6 months applied in the appointment.

The salary of the position is based on level 2 of the demands level table for teaching and research personnel in the salary system of Finnish universities. The starting salary will be 2200-2500 euros/month, depending on the appointee’s qualifications and experience.

University of Helsinki offers comprehensive services to its employees, including occupational health care and health insurance, sports facilities, and opportunities for professional development. The Faculty of Medicine has strong activities towards enhancing gender equality, diversity and employee wellbeing. The International Staff Services office assists employees from abroad with their transition to work and life in Finland.

To apply for this fully funded PhD training position, please submit the application through the University of Helsinki electronic recruitment system by clicking on Apply for job by September 30, 2020. Internal applicants (i.e., current employees of the University of Helsinki) please submit your applications through the SAP HR portal.

In your application, please include:

– a CV (with possible list of publications)
– a copy of your transcript records (the courses completed during MSc program; if you have not yet obtained your MSc degree, please include an estimated date for this)
– contact details of 1-3 references
-a cover letter (maximum 1 page) describing your research interests, experience in laboratory work and why you are an excellent candidate for this project

Due date

30.09.2020 23:59 EEST

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Post expires on Wednesday September 30th, 2020

Postdoc­toral and/​or PhD po­s­i­tions in cell biology of the en­do­cytic cyto­skel­eton

Helsinki Institute of Life Science, HiLIFE (https://www.helsinki.fi/en/helsinki-institute-of-life-science), is a new life science institute at the University of Helsinki established in 2017 supporting high quality research across campuses and life science faculties. HiLIFE builds on existing strengths, new recruits and partnerships to create an attractive international environment for solving grand challenges in health, food, and environment. It coordinates research infrastructures in life sciences, provides research-based interdisciplinary training and supports researchers within its units and partner faculties. In 2019 HiLIFE has a staff of 600 and budget of 59 M€.

Our lab is located within the HiLIFE unit Institute of Biotechnology, Viikki campus. The Institute of Biotechnology (BI) (https://www.helsinki.fi/en/hilife-institute-of-biotechnology) is an international research unit within the Helsinki Institute of Life Science (HiLIFE) of the University of Helsinki. Research groups at BI conduct research and develop infrastructures in biotechnology and modern biosciences at the highest international level, actively applying the results for the benefit of society.

The Almeida-Souza Lab at HiLIFE invites applications for

Post-doctoral researcher and/or PhD student in cell biology of the endocytic cytoskeleton

We offer you a highly collaborative, supportive and international research environment. The working language of the institute is English. Our research goal is to understand the molecular logic behind the dynamics of the actin cytoskeleton at endocytic sites and how disturbances in this process affect physiology and disease progression.

Projects in the lab involve Super-resolution imaging and analysis, protein biochemistry, CRISPR/Cas9 genome engineering and drug screens. Please look at our webpage for more details (https://www.helsinki.fi/en/researchgroups/endocytic-cytoskeleton-biology). Successful candidates will be able to decide which projects suit best their interests and expertise.

Our lab offers a 3-year fixed-term contract for postdocs and a 4-year fixed-term contract for PhD students. Candidates will be encouraged to apply for their own funding.

We seek motivated individuals willing to contribute positively to the research team and the HiLIFE community at large. Our lab is committed to build an environment where everyone is respected and valued. Importantly, we believe that science should be fun and exciting.

The successful Doctoral and/or Postdoctoral candidates will hold an excellent Master Degree (or equivalent) and/or PhD in Biology with a specialization in Cell Biology and/or Biochemistry. In addition, the Postdoctoral candidate will have a proven record of excellence in the above-mentioned research areas, whereas the Doctoral candidate will have a strong potential for excellence in research. Previous experience with cellular and molecular biology techniques is essential. Experience with super-resolution microscopy and/or protein purification using multiple expression systems is definite plus.

To apply, please submit your application using the University of Helsinki electronic recruitment system by clicking on the Apply link below. Internal applicants (i.e., current employees of the University of Helsinki) please submit your applications through the SAP HR portal. Upload a single pdf-file containing a one-page cover letter outlining your relevant work experience and motivation to work on our research group, your CV and contact information for 2-3 referees. Please indicate whether you are applying for the PhD student or Postdoc position.

The application deadline is January 6th, 2020, but review of applications will begin immediately and continue until the position is filled.

For informal enquiries, contact leonardo.almeida-souza@helsinki.fi. In case you need technical support with the recruitment system, please contact recruitment(at)helsinki.fi.

The University of Helsinki, founded in 1640, is one of the leading multidisciplinary research universities and ranks among the top 100 international universities in the world. It is currently investing heavily in life sciences research. The University of Helsinki has an international academic community of 40,000 students and staff members, and it offers comprehensive services to its employees, including occupational health care and health insurance, sports facilities, and opportunities for professional development.

Due date

06.01.2020 23:59 EET

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Post expires on Monday January 6th, 2020