Diary id: PAR 2019/835
Employment level: Fixed term
Location: Institute of Biomedicine
Apply by: 2019-07-05
The Institute of Biomedicine is involved in both research and education. In both of these The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell – what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them.
The Institute is composed of the following four departments:
- The Department of Infectious Diseases
- The Department of Microbiology and Immunology
- The Department of Medical Biochemistry and Cell Biology
- The Department of Laboratory Medicine
At present, the institute has about 370 employees and approximately 400 million SEK in total assets.
We offer 24 month full time postdoctoral position within the research group led by Professor Michael Kann, Department of Infectious Diseases, Institute for Biomedicine, Sahlgrenska academy at the University of Gothenburg, Sweden. The focus of the research group is the understanding how parvo- and hepatitis B viruses transport their genome into the nucleus. The newly created group consists of 1 professor, 1 engineer, and 1 technician, closely collaborating with the clinical virologists at the department and with cancer researchers. A PhD student is currently hired. The group has extensive collaboration with other international universities. The research is interdisciplinary at the interface between fundamental and clinical virology, and cell biology.
Subject area description
Parvoviruses are not only pathogens of a variety of organisms but also used as therapeutic agents. E.g. parvovirus PVH-1 is used in clinical trial for treatment of glioblastoma. Adeno-associated viruses (AAV) are a major platform in gene therapy. All parvoviruses have in common that they are very inefficient and hundreds of viral particles are needed for infection/transduction.
Our group thus likes understanding this obstacle, which is linked to parvovirus intracellular trafficking. A better knowledge about the underlying molecular mechanisms will thus help improving gene therapy and cancer treatment.
The postdoctoral fellow is expected to conduct research with the aim of identifying the molecular mechanisms and factors involved in parvovirus trafficking and genome release. It is expected that the successful candidate participates also in hepatitis B virus research, in which similar techniques are used. The project is largely based on fluorescence microscopy of living cells and FACS analysis. Techniques of molecular biology as e.g. Western blot, PCR, virus and protein purification by affinity columns and ultracentrifugation are needed for verification of microscopical results. The work also includes authoring/co-authoring scientific publications and presenting research at international scientific conferences.
An achieved doctoral degree is compulsory for a position as postdoctor at Göteborg University. The doctoral thesis shall be in a relevant area according to the specific position stated here. Since a position as postdoctor aims to give new holders of the doctorate the opportunity mainly to strengthen and develop their scholarly proficiency, we aim for those who have a doctoral degree not older than 3 years counting from last date of application.
The qualifications for academic positions are given in Chapter 4, Section 3 – 4 of the Higher Education Ordinance.
PhD in relevant area, as well as excellent scientific production in relation to the time passed since completing PhD are required. A high degree of independence including extensive experience of practical molecular and microbiological analyses with the techniques indicated (confocal fluorescence microscopy, FACS), experience in virus entry using these techniques, previous international postdoc experience, excellent communicative skills including fluent verbal and written scientific English, experience from working at differerent labs and abilty to work successfully are all additional qualifying criteria.
Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 – 4 of the Higher Education Ordinance.
The employment is full time and temporary, two years, with placement at the Institute of Biomedicine. First day of employment as agreed.
For further information:
Please contact Professor Michael Kann, e-mail: Michael.firstname.lastname@example.org
Union representatives at the University of Gothenburg: http://www.gu.se/english/about_the_university/job-opportunities/union-representatives
How to apply
In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. The selection of candidates is made on the basis of the qualifications registered in the application.
The application is to be written in English.
The application should contain:
- A cover letter giving a brief description of previous research experience, and a motivation to why you are applying
- A CV including a list of publications
- Proof of completed PhD
- Contact details of two references
The University of Gothenburg promotes equal opportunities, equality and diversity.
Salary is determined on an individual basis.
Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.
Read the job description at the university homepage
The University of Gothenburg tackles society’s challenges with diverse knowledge. 47 500 students and 6 400 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.
Post expires on Friday July 5th, 2019