Tag-arkiv: Umeå University

Two postdoc positions in physiology of oxygen sensation

Applications are invited for two postdoc positions in the laboratory of Dr. Changchun Chen at Umeå University, Sweden, working on oxygen sensation in the nematode C. elegans. The lab is affiliated to Wallenberg Centre for Molecular Medicine (WCMM) and located in Umeå Centre for Molecular Medicine (UCMM). Both positions are of two-year-full-time employment, funded by a starting grant from European research council (ERC) (2019-2023). Positions will be available from January 2019.

Project description
The lab aims at delineating the molecular underpinning of O2 sensing, and dissecting the neural circuit controlling behavior in response to O2 variations. Projects running in the lab include the elucidation of how cytokines exert effects on circuit function in the context of O2 sensation, using both C. elegans and cultured mammalian neurons (Chen et al, Nature 2017). Projects involve high-throughput genetic screen, genomics, biochemistry, calcium imaging, optogenetics and RNA profiling of single cells. The lab received funding from European research council, Wallenberg Centre for Molecular Medicine and Swedish Research Council.

Qualifications
The candidate shall have a PhD in a relevant subject (biology, genetics or biochemistry) or be due to complete a PhD within 6-7 months. Priority will be given to highly motivated applicants who can work independently within a highly interactive group. The ideal candidate shall have demonstrated expertise in genetics, cell biology, biochemistry or relevant areas. Previous experience in C. elegans will be a plus but not essential.

Please submit your application combined in one pdf file:

1.     A cover letter including your past achievements and research interests

2.     A curriculum vitae including publication list and the contact information of two references

For more information, please contact Changchun Chen (changchun.chen@umu.se) and visit our webpage at http://www.wcmm.umu.se/gruppledare/gruppledare#Changchun.


About Umeå University
Umeå University is dedicated to providing creative environments for learning and work. We offer a wide variety of courses and programmes, world leading research, and excellent innovation and collaboration opportunities. More than 4 300 employees and 31 500 students have already chosen Umeå University. We welcome your application!

The Faculty of Medicine, which consists of 13 departments, is responsible for biomedical research and courses in the field of nursing and health care and has an extensive research and graduate education in more than 80 subjects.

Admission

By agreement

Contact

Changchun Chen, Associate senior lecturer

090-786 71 35

Registration number

AN 2.2.1-1938-18

Salary

Monthly salary

Union representative

SACO

090-786 53 65

SEKO

090-786 52 96

ST

090-786 54 31

Read the job description at the university homepage

Apply

before

2019-01-04

Post expires on Friday January 4th, 2019

PhD student position in Chemistry – Fabrication of Polymeric Membranes

We are now recruiting a PhD student to a project where we synthesis new polymers and fabricate polymeric membranes based on these polymers for separation applications. The applicant should have experience in the synthesis of polymer, polymeric membrane formation, and characterizing the prepared membranes. Application deadline is January 15th, 2019.

Description
The focus of the PhD project is research on synthesis of new polymers and fabrication of polymeric membranes for separation applications. Further targets of this project are to investigate the preparation conditions on the performance of the produced membranes, studying the thermodynamic and kinetic aspect of membrane formation, optimizing the fabrication parameters, and evaluating the potential of the prepared membranes for pilot scale separation. The work which will be carried out in the project is largely experimental. The project is based on a collaboration between industry and university.

Admission requirements
You are required to have completed a second- cycle level degree, or completed course requirements of at least 240 ECTS credits, of which at least 60 ECTS credits are at second-cycle level, or have an equivalent education from abroad, or equivalent qualifications.

To fulfil the specific entry requirements for studies at third-cycle level in chemistry, you are required to have completed first-cycle courses of at least 90 ECTS credits within the fields of chemistry or chemical technology, or other closely related subjects considered directly relevant to the specialization in question. Among these 90 ECTS credits, at least 15 ECTS credits shall have been acquired at the second-cycle level within the specialization or an equivalent subject.

Fundamental knowledge about the synthesis of polymer, polymeric membrane formation, and characterizing the prepared membranes are mandatory. Documented experience of laboratory work in the areas of separation science and organic synthesis is meriting. Part of the experimental work will involve designing and building unique equipment. Familiarity with electronics and a reasonable amount of handiness is therefore needed to successfully carry out the work.

Very good communication skills in English, both orally and in writing are required. In order to succeed as a PhD student, you must be creative, goal-oriented and devoted to work. You must also have good interpersonal skills, be resourceful, and have a high degree of independence. You should also have a keen interest in polymer chemistry, alternatively, in organic chemistry, industrial chemistry, separation sciences, and be prepared to adopt scientific and technological challenges.

About the position
The position is intended to result in a doctoral degree and the main task of the PhD students is to pursue their doctoral studies, which includes participation in research, in the compulsory department seminar series, and postgraduate courses. Teaching and other departmental work can be assigned (up to a maximum of 20% of full working time). The employment is time-limited to four years of full-time work, with extension of up one year to compensate for part time teaching and other duties. Salary is set in accordance with the established salary ladder for PhD positions.

The application
A complete application should contain the following documents:

  • An application letter (see below for expected contents) which should include your contact information;
  • A curriculum vitae including a listing of formal merits,
  • A digital copy of your completed BSc and/or MSc thesis and, if applicable, other research publications;
  • Verified copies of degree certificates translated into Swedish or English, including documentation of completed academic courses and obtained grades; and
  • Contact information to at least three reference persons

As part of your application letter you are requested to account for a) the driving forces that motivate you to pursue studies at the PhD level in this area of science and in our group in particular; b) your career ambitions; and c) the expectations you have on working life after you have completed a doctoral degree. You are also requested to explain why you are convinced that your previous study background and work experience, combined with other items listed in the CV attached to your application, are particularly useful for solving the research challenges listed in this advertisement.

Your application should be written in Swedish or English and be submitted via our e-recruitment system MyNetwork Pro/Varbi (link below) on January 15th, 2019 at latest.

For specific information on this position, contact Dr. Naser Tavajohi Hassan Kiadeh, naser.tavajohi@umu.se, +46(0)90-7866061.

For general information on PhD studies in chemistry, contact the director of postgraduate studies, prof. Elisabeth Sauer-Eriksson, elisabeth.sauer-eriksson@umu.se, +46(0)90-7865923.

We politely but firmly decline any contacts from recruitment agencies in connection to this ad.

Information about the department
The Department of Chemistry is part of the Faculty of Science and Technology. It is currently the workplace of about 200 employees, including about 50 postgraduate students. The research is a strong and expanding part of our activities, which covers three major areas: Biological Chemistry, Environmental and Biogeochemistry, and Technical Chemistry. These three focus areas are also mirrored in programs and courses taught by our staff at the undergraduate and graduate levels. The department is also a strong partner in The Chemical-Biological Centre (KBC). Information about the Department of Chemistry; www.chemistry.umu.se/english. Information about postgraduate education can be found on the Faculty of Science and Technology website: http://www.teknat.umu.se/english/doctoral-studies/. For more information about working at Umeå University, https://www.umu.se/en/work-with-us/

Admission

By agreement

Contact

Naser Tavajohi Hassan Kiadeh

090-7866061

Registration number

AN 2.2.1-1967-18

Salary

Monthly salary

Union representative

SACO

090-786 53 65

SEKO

090-786 52 96

ST

090-786 54 31

Read the job description at the university homepage

Apply

before

2019-01-15

Post expires on Tuesday January 15th, 2019

PhD student position in Chemistry with focus on Organic Chemistry

We are now recruiting a doctoral student to a research project within chemical biology. The applicant should have experience in organic chemistry research and be interested in the design and development of small drug-like molecules, and fulfill the other requirements. Last day to apply is 25 January 2019.

Work description
The department of chemistry at Umeå University holds a strong position in the field of chemical biology where collaborations over disciplines are a key to be able to answer complex research questions. In this employment as doctoral student you will be working in such a project with focus on the design and development of small drug-like molecules that selectively inhibit Mycobacterium tuberculosis (Mtb) ability to convert to a tolerant state. In this tolerant state Mtb is persistent and unsensitive to antibiotics and immune responses. It is known that Mtb convert to this tolerant state but there are still a lot of gaps in the knowledge and more detailed mechanistic understanding is desired. We have named our compounds”Mycobacterial tolerans inhibitors” (MTIs) and they are very interesting both as chemical research tools to gain deeper mechanistic knowledge but also because they have therapeutic potential.

The main objective with this doctoral research project is to develop these molecules further in terms of their activity and selectivity but also to introduce chemical groups/features that make them more valuable as research tools in the aim to unravel the exact MTI mode of action. The work thus mainly concerns synthetic organic chemistry. However, because the evaluation of the compounds activity and selectivity are so central to the project you will also learn different methods to test the compounds. You will also attend group meetings with focus on the design and synthesis of the molecules as well as project meetings with collaborators where the use of the molecules in biological studies will be discussed. Several international research groups with complementary expertise are involved in the research program and regular meetings with these collaborators are also part of the work.

Requirements
To be admitted for studies at third-cycle level you are required to have completed a second-cycle level degree, or completed course requirements of at least 240 ECTS credits, of which at least 60 ECTS credits are at second-cycle level or have an equivalent education from abroad, or equivalent qualifications.

To fulfil the specific entry requirements to be admitted for studies at third-cycle level in chemistry, you are required to have completed first-cycle courses of at least 90 ECTS credits within the field of chemistry or another subject considered to be directly relevant to the specialization in question. Of those 90 ECTS credits, at least 15 ECTS credits shall have been acquired at second-cycle level within organic chemistry or an equivalent subject.

The successful candidate must have very good command of written and spoken English. Experience in research related to synthetic organic chemistry, achieved through for example a diploma work in a research group or similar, is also a requirement. It’s a merit if the research related to synthetic organic chemistry is connected to chemical biology or equivalent. You should be enthusiastic, like experimental work, be precise, have good working ethics and moral, and be able to work both independent and in a group.

Terms of employment
The employment is expected to result in a doctoral degree and the main assignment for the doctoral student is thus to be part of the research education, which includes participation in the described research project but also to take relevant courses. Teaching and other departmental work (up to a maximum of 20%) can be included. The employment is limited to four years at full time or up to five years if teaching and other departmental work is performed. The salary is fixed according to the established salary level for doctoral students.

Application
The application should include the following:

  • CV
  • A personal letter where you describe your scientific background and interests, previous research experience and why you are interested in the position
  • Verified copies of graduation degrees, or equivalent, including documentation of performed academic courses and obtained grades as well as other relevant certificates (e.g. English knowledge)
  • Name and contact information to at least two reference persons

The application is submitted through our e-recruitment system, log in and apply at the bottom of the page. Apply no later than 25 January 2019.

Contact Fredrik Almqvist for more information, telephone: +4670-3979097, e-mail: fredrik.almqvist@umu.se

Information about us
The Department of Chemistry is one of the largest departments at the Faculty of Science and Technology with approximately 200 employees, out of which 40 are doctoral students. The department is located within the Chemical Biological Centre (www.kbc.umu.se) at Umeå University and provides excellent facilities and state-of-art equipment and platforms in a creative, inspiring, international and highly interactive environment. We welcome your application!

Admission

By agreement

Registration number

AN 2.2.1-1993-18

Salary

Monthly salary

Union representative

SACO

090-786 53 65

SEKO

090-786 52 96

Applybefore

2019-01-25

Post expires on Friday January 25th, 2019

Postdoctoral position in computational biology

Postdoctoral position in computational biology: Decoding plant stress responses with network science methods

The Department of Physics is looking for an exceptional Postdoc to join our interdisciplinary group at Integrated Science Lab, IceLab, where we work on solving life science problems with tools from physics, mathematics, and computer science. This two-year full-time position is part of a large multidisciplinary 5-year project that also includes researchers at the Chemical Biological Centre (www.kbc.umu.se) and Umeå Plant Science Centre (www.upsc.se), two stimulating research environments at Umeå University.

Project description and working tasks
Large amounts of crop and forest production are lost every year to unfavourable weather conditions, and climate change will further increase the losses. To develop plants that maintain yield under adverse conditions, we need a mechanistic understanding of plant stress tolerance. We propose that plant stress responses are mediated by a central regulatory hub, the Mediator complex. The Mediator is an evolutionary conserved multiprotein complex involved in gene expression regulation and chromatin remodelling; essential processes for regulating plant stress responses. It integrates external signals from different receptors by transmitting promoter element-bound transcription factors to RNA polymerase II. Several functions of the Mediator are still unknown, especially how specific Mediator subunits integrate different signalling pathways and how they transfer these signals to RNA polymerase II to regulate the expression of target genes. To reveal the regulatory mechanisms of Mediator and to functionally define stress responses at all organisational levels, we perform module specific analysis of global changes in gene expression, mediator DNA binding, and mediator complex composition at stress. To enable the integration and interpretation of these complex data sets, we will use network methods as well as other computational tools to construct a model of the signalling networks that regulate plant stress responses.

The postdoctoral project is part of the 5-year multidisciplinary project “Decoding Signalling Networks Controlling Plant Stress Responses”, financed by the Swedish Foundation for Strategic Research. The project provides challenging postdoctoral training for multiple postdocs, who will together solve problems using methodologies from biology, physics, and computer science.

A successful candidate will study how the Mediator functions as a regulatory hub that integrates stress signals to control changes in gene expression, required for the acclimation to stress. Using a suite of computational tools, the postdoc will identify modules of co-regulated genes with shared regulatory motifs and gene products with conserved biological functions regarding stress responses. The postdoc will be supervised by Martin Rosvall in IceLab, co-supervised by Åsa Strand at Umeå Plant Science Centre and Stefan Björklund at Department of Medical Biochemistry and Biophysics, work in close collaboration with senior research engineer Matilda Rentoft, and be a part of dynamic and multidisciplinary environments, which also provide technical support.

The position is a two-year full-time employment that will open in March 2019, or at a later date according to an agreement.

Qualifications
To qualify for the position, the candidate should have a PhD degree or a foreign degree that is deemed equivalent, in applied mathematics, bioinformatics, computer science, physics, or a relevant field. To be eligible, the degree should have been completed a maximum of three years before the end of the application period unless certain circumstances exist.

We are looking for a highly motivated and responsible candidate who wants to develop as an individual scientist as well as a research team member. The candidate should have extensive training in statistics or computational modelling with languages such as C++, Python or R, and be passionate about leveraging statistical methods and machine learning algorithms to address biological questions. Working experience in large-scale sequence analysis is an advantage. An ability to perform research independently as well as in a team, and good skills in the English language, are essential.

Application
The application should include:
1. A cover letter summarizing your qualifications, your scientific interests, and your motives for applying (max 2 pages),
2. A curriculum vitae (CV),
3. A publication list,
4. Copies of doctoral degree certificate and other relevant degree certificates,
5. Copies of the PhD thesis and relevant publications,
6. Names and contact information of two references,
7. Other documents you wish to claim.

The application must be written in English or Swedish. The application is made through our electronic recruitment system. Documents sent electronically must be in Word or PDF format. Log in to the system and apply via the button at the end of this page. The closing date is 2019-01-31.

Information
For more information, contact Martin Rosvall, martin.rosvall@umu.se or Matilda Rentoft, matilda.rentoft@umu.se.
Research: http://www.tp.umu.se/~rosvall
Mapping tools: http://mapequation.org
Research environment: http://www.icelab.se

We look forward to receiving your application!

Admission

March 2019, or at a later date according to an agreement.

Contact

Martin Rosvall

070-2391973

Registration number

AN 2.2.1-1804-18

Salary

Monthly salary

Union representative

SACO

090-786 53 65

ST

090-786 54 31

Apply 

before

2019-01-31

Post expires on Thursday January 31st, 2019

Postdoctoral researcher, Software Technology, Resource Management Systems

The Department of Computing Science at Umeå University (www.cs.umu.se) is seeking a candidate for a post-doctoral researcher position in software technology focusing on resource management systems for a collaboration project with The Royal Institute of Technology (KTH), Stockholm. The position is funded by The Knut and Alice Wallenberg Foundation through The Wallenberg AI, Autonomous Systems and Software Program (WASP), which is Sweden’s largest research program ever.

The position is within the Distributed Systems group at Umeå University, which is a large, dynamic, and well-recognized research group comprised of more than 20 people from about 10 different countries. The group’s research focuses on the autonomous management of resources and applications to support the future digitized society. Target infrastructures range from single large-scale cloud datacenters to the mobile edge clouds. The research spans from basic research to applied research, and even innovation via spin-off companies. Collaborations are performed with industries like Google, IBM, Intel, Red Hat, and Ericsson, as well as universities and institutes such as Princeton University, Imperial College London, Lawrence Berkeley Lab, Nanyang, Technological University (NTU), Singapore, and many more.

See www.cloudresearch.org for a presentation of the group as well as an overview of ongoing research projects and publication lists.

Project description and tasks
The project addresses the increasingly important problem of software bloat, i.e. the fact that software, throughout the whole software stack, is rapidly growing in size with consequences such as substantially increased resource consumption, reduced performance, and increased vulnerability for security threats.

This project investigates code debloating as well as the management of specialized and debloated software. These approaches aim to detect and remove parts of an application’s compiled code that are not or are seldom used. Bloated code has many side effects including, performance degradation, wasting computing resources, and increased energy footprints. The automatic process of software debloating and execution of debloated software is tightly interrelated with semi-autonomous resource and application management, requiring both new functionality and adjusted configuration and optimization. The expected benefits of specialization and debloating are reduced security risks and attack surface, smaller programs, and faster execution. This is a highly ambitious project with very high potential to impact the software industry, while publishing very high-quality publications in top-tier venues.

The postdoc is expected to develop an autonomous research activity in the area of management of specialized and debloated software, publish in top conferences and journals in the fields of software engineering and systems, and tightly collaborate and cooperate with our project partners at KTH. The applicant must also be ready to take part in supervision activities (Masters and PhD students), grant proposal preparation, and the research groups active engagement in the international scientific and industrial activities.

The appointment is for 2 years full-time employment. The employment will start on April 1, 2019, or as otherwise agreed.

Qualifications
Applicants must have earned a PhD or a foreign degree that is deemed equivalent to a PhD in Computer Science or a subject relevant for the position. The PhD degree should not be more than three years old by the application deadline, unless special circumstances exist.

The candidate should have a strong background in at least two of the following areas:  cloud systems software, static and dynamic program analysis, compiler techniques and optimization, operating systems, programming languages, and resource management. The candidate should be comfortable with systems level programming in general. Moreover, strong research merits and excellent publications are required. Proficiency in English, both spoken and written, is required, as well as good ability to co-operate and take own initiatives.  The project will be adapted based on the competence of the selected candidate, and his/her interests.

Application
A complete application should include:

  • Introductory letter including a 2-page statement of research interests relative to the above topics and a motivation of why your expertise is appropriate for the position.
  • Curriculum Vitae (CV) including a complete list of scientific publications.
  • Copies of doctoral degree certificates, including documentation of completed academic courses and obtained grades, and other relevant degree certificates.
  • A copy of your PhD thesis and copies of (max 5) original research publications relevant to the above topics, numbered according to the publication list.
  • Names and contact information for three persons willing to act as references.
  • Any other information relevant for the position such as description of software development experience, or previous industry experience.

Please observe that all material needs to be written in Swedish or English. If material is submitted in other languages a translation to Swedish or English must be included. As we strive for a more balanced gender distribution within the department, we encourage women as applicants.

Welcome with your application
Applications must be submitted electronically using the e-recruitment system of Umeå University, and be received no later than January 31, 2019. Reference number AN 2.2.1-2025-18.

Further information
For further information, please contact Professor Erik Elmroth, elmroth@cs.umu.se.

More information about the hosting research group and Umeå University can be found at
http://www.cloudresearch.org/ , http://www.umu.se/

Admission

2019-04-01 or as otherwise agreed

Contact

Erik, Elmroth, professor

+46 70 315 3928

Registration number

AN 2.2.1-2025-18

Salary

Månadslön

Union representative

SACO

090-786 53 65

SEKO

090-786 52 96

before

2019-01-31

Post expires on Thursday January 31st, 2019