Ref. No. SU FV-3449-19
at the Department of Materials and Environmental Chemistry. Closing date: 5 November 2019.
The Department of Materials and Environmental Chemistry (MMK) is one of the largest departments at the Faculty of Natural sciences with about 150 employees. The teaching focuses on general chemistry, inorganic, material chemistry and analytical chemistry. Research activities of MMK in the areas of Materials and Solid-State Chemistry focus on different classes of materials; e.g. ceramics and glasses, self-assembled and porous materials, and soft matter. The work often encompasses synthesis, characterization by X-ray and neutron diffraction and electron microscopy, NMR studies, modelling with computer simulations of materials with a potential for various applications. Research activities of MMK in the areas of Analytical Chemistry mainly focuses on developing advanced analytical techniques and methods for determination of organic compounds and biomolecules. This includes the whole Analytical Chain from sampling and clean-up, to chromatography, mass spectrometry and data analysis. Environmental aspects are also an important part of the research activities.
Project title: New cryo-EM methods for determination of 3D atomic structures and charges in biomolecules.
Knowing the 3D atomic structures is crucial for understanding the functions of macromolecules and chemical processes in biological systems. The information is also important for drug design. X-ray diffraction is presently the most important technique but requires large crystals. Electron microscopy (EM) and electron diffraction (ED) can be used for studying nano and micron-sized particles/crystals. Single particle cryo-electron microscopy (cryo-EM) has made important breakthroughs for structure determination of macromolecules (awarded Nobel Prize in Chemistry 2017).
The group of Prof. Zou is internationally leading in developing and applying electron crystallographic methods to study novel atomic structures. Recently the method based on 3D electron diffraction (3D ED), also known as MicroED, has shown to be powerful in determining structures of novel inorganic crystals and pharmaceutics from nano- and microcrystals. It was identified as one of the 2018 ten breakthroughs by Science (vis.sciencemag.org/breakthrough2018/).
The PhD project aims at developing and applying new 3D ED methods to obtain structure information from microcrystals of pharmaceutics and proteins. The project is funded as one of the 22 Wallenberg Scholars awards 2018 by the Knut and Alice Wallenberg Foundation (kaw.wallenberg.org/en/xiaodong-zou). The focus can be either method development including programming and machine learning, or applications of the methods on new pharmaceutics and proteins using advanced cryo-EM techniques.
The student will be part of a large group working on one or all the subprojects, depending on her/his background and interests. The project requires close collaboration with synthetic chemists and biochemists from academia and industry. She/he should have a strong collaborative and communication skill, be self-motivated and a good team player. Good knowledge on computers and programming are desired but not necessary. The candidate should have a Master or equivalent degree in Physics, Biochemistry, Chemistry or Materials Sciences. For more information see the group homepage: http://www.mmk.su.se/zou.
In order to meet the general entry requirements, the applicant must have completed a second-cycle degree, completed courses equivalent to at least 240 higher education credits, of which 60 credits must be in the second cycle, or have otherwise acquired equivalent knowledge in Sweden or elsewhere.
In order to meet the specific entry requirements, the general syllabus for doctoral studies in the field of Chemistry is valid. Those studies should include at least one specialized course or a thesis in the research subject. In order to facilitate the evaluation of merits and suitability for the PhD studies your curriculum vitae (CV) should contain information about the extent and focus of the academic studies. The quantity (as part of an academic year) and the quality mark of courses in chemistry and physics are of particular interest. Please, state titles of undergraduate theses and project works.
The qualification requirements must be met by the deadline for applications.
The selection among the eligible candidates will be based on their capacity to benefit from the training. The following criteria will be used to assess this capacity: the candidates’ documented knowledge in a relevant field of research, written and oral proficiency in English, the capacity for analytical thinking, the ability to collaborate, as well as creativity, initiative, and independence. The assessment will be based on previous experience and grades, the quality of the degree project, references, relevant experience, interviews, and the candidate’s written motivation for seeking the position.
A short list will be set up and interviews with the top candidates will be carried out at the department or via internet.
Economic support for the PhD studies are guaranteed for full time studies during the time period agreed on in the individual study plan. The studies does normally mean four years full time studies. You are encouraged to contact the project leader for more information about the project.
Admission Regulations for Doctoral Studies at Stockholm University are available at: www.su.se/rules and regulations.
Terms of employment Only a person who will be or has already been admitted to a third-cycle programme may be appointed to a doctoral studentship.
The term of the initial contract may not exceed one year. The employment may be extended for a maximum of two years at a time. However, the total period of employment may not exceed the equivalent of four years of full-time study.
Doctoral students should primarily devote themselves to their own education, but may engage in teaching, research, and administration corresponding to a maximum of 20 % of a full-time position.
Please note that admission decisions cannot be appealed.
Stockholm University strives to be a workplace free from discrimination and with equal opportunities for all.
For more information, please contact Professor Xiaodong Zou, telephone: +46 8 16 23 89, email@example.com, or he Head of the Department, Professor Gunnar Svensson, firstname.lastname@example.org.
Ingrid Lander (Saco-S), telephone: +46 708 16 26 64, email@example.com, Alejandra Pizarro Carrasco (Fackförbundet ST/Lärarförbundet), telephone: +46 8 16 34 89, firstname.lastname@example.org, email@example.com (SEKO), and PhD student representative, firstname.lastname@example.org.
Apply for the PhD student position at Stockholm University’s recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the advertisement, and that it is submitted before the deadline.
Please include the following information with your application
- Your contact details and personal data
- Your highest degree
- Your language skills
- Contact details for 2–3 references
and, in addition, please include the following documents
- Cover letter
- CV – degrees and other completed courses, work experience and a list of degree projects/theses
- Project proposal/Research proposal describing:
– why you are interested in the field/project described in the advertisement
– why and how you wish to complete the project
– what makes you suitable for the project in question
- Degree certificates and grades confirming that you meet the general and specific entry requirements (no more than 6 files)
- Letters of recommendation (no more than 6 files)
- Degree projects/theses (no more than 6 files).
The instructions for applicants are available at: Instructions – Applicants.
You are welcome to apply!
Stockholm University – our education and research produce results.
Closing date: 05/11/2019
Post expires on Tuesday November 5th, 2019