Tag-arkiv: RegionH

Post doc position in translational diabetes research

At Steno Diabetes Center Copenhagen (SDCC) we are seeking a post doc to join our research group, Type 1 Diabetes Biology (headed by Flemming Pociot). SDCC is part of the Capital Region of Denmark (RegionH) and is a leading research institute and specialized diabetes care hospital. The post doc will be part of the Immuno Diabetology team headed by Joachim Størling.
About the project 
To support our pipeline of clinical and translational research activities, we wish to apply a new methodology to measure energy metabolism in living cells using the “Seahorse” technology. The post doc we are seeking will undertake the task of establishing the technique in our laboratory and applying it on research projects at SDCC.
There are two overall aims of the project: i) to perform metabolic measurements of peripheral blood mononuclear cells (PBMSc) isolated from patients with diabetes who participate in clinical trials at SDCC. Information about the metabolic activity in PBMCs may provide mechanistic insight into therapeutic treatments and may serve as a potential “biomarker” of treatment efficacy. Applying the Seahorse technology in a patient-near context at SDCC allows for fresh PBMC preparation and analyses on site; ii) to perform metabolic measurements on isolated pancreatic islets and beta cells exposed to different diabetes-relevant compounds to address if these alter their energy metabolism.
 
What we offer 
We offer an exciting multidisciplinary research environment with top-class laboratory and office facilities. A friendly and sociable atmosphere and intercross collaborations and research disciplines are characteristics of SDCC. We have large networks of national and international relations offering great possibilities for synergies with groups outside the house.
Terms
The post doc candidate will be offered a full-time position for a period of two years. Employment will be in accordance with the relevant collective agreement within the Capital Region of Denmark.
Qualifications 
The candidate must have completed her/his PhD. The candidate will preferably have an interest and skills in cell biology and diabetes research. Candidates with past experience in the Seahorse technology especially in the combination with PBMCs and/or islets are particularly qualified. Creativity, independent thinking, good communication skills, and the ability to work in a team are all important qualities. The successful candidate will be responsible for the daily management of his/her research project(s) in coordination with the team leader and other members of the group.
Application & further information
Submit your application including your CV, documentation of diplomas (Master degree, PhD degree), names and contact information of 1-2 references no later than May 15, 2018. The position is available now.  For further information please contact team leader and senior researcher Joachim Størling at +45 30 91 33 99.
About Steno Diabetes Center Copenhagen
Steno Diabetes Center Copenhagen is specialized in patient care, research, and prevention of diabetes, and in education of health care professionals within diabetes. SDCC is the biggest diabetes clinic in Scandinavia and treats annually more than 9.000people with diabetes from the Capital Region of Denmark. For more information visit www.sdcc.dk and follow Steno Diabetes Center Copenhagen on LinkedIn and Twitter.

Post expires on Tuesday May 15th, 2018

PhD student position in cranial pain mechanisms

Department of Clinical Experimental Research, Glostrup Research Institute, Copenhagen University Hospital, Rigshospitalet, Denmark
We are looking for outstanding and highly motivated candidates with background in neurobiology, pharmacology and scientific methodology.
We employ a wide range of different biochemical methods and animal models to address our scientific questions. The primary responsibility includes conducting research with a clear translational focus. The development of different methods to achieve results of high quality and of different character is desirable.
Project title: Detection and function of neuropeptides in the trigeminal ganglion and mechanisms involved in controlling messenger molecule release.
Background: This PhD is designed to develop the understanding of cranial pain mechanisms such as those associated or involving clinical conditions such as migraine and trigeminal neuralgia. The work will center around the trigeminal system – the trigeminal neurons and glial cells, its central and peripheral ramifications, and the neuronal messenger molecules associated cells.
Main aim and Importance: To develop methods to evaluate neuropeptides and their receptors function in different parts of the trigeminovascular system. The work will have importance in understanding cranial pain conditions.
Qualifications: The PhD work will involve several basic laboratory methods: It will be of considerable value that the candidate show evidence of knowledge in immunohistochemistry (a key method) as well as of organ culture and myography of vascular smooth muscle. It is important that the candidate shows genuine interest and willingness to learn, both the theoretical side as well as the practical part of our laboratory environment. Good collaborative ability is appreciated.
The candidate should be familiar with basic experiments and having approved certificate to handle laboratory animals is an advantage. It would be an additional advantage if the candidate has experience with handling rodents and dissecting tissues.
The position is a 3 year position. The starting date will be after agreement.
Application: The CV including a publication list, copy of latest degree certificate, a description of previous research and other activities of relevance for the position, including documents showing expierence in animal experiments and a brief description of current research interest should be submitted (total maximum of one page). Names and addresses of at least two people able to provide references for the candidate should also be provided.
Information: Professor Karin Warfvinge (Karin.Birgitta.Warfvinge@regionh.dk)

Application due

5/4/2018

Post expires on Friday May 4th, 2018