Tag-arkiv: Karolinska Institutet

Postdoctoral Researcher in Polymer Chemistry

Ming Wai Lau Centre for Reparative Medicine, KI, Hong Kong

Ming Wai Lau Centre for Reparative Medicine (MWLC) aims to contribute to the improvement of human health by conducting cutting-edge research in reparative medicine and related subjects, by creating a new platform for synergies between academia and innovation in Sweden and Hong Kong as well as China, and fostering future leaders in both academia and industry.

Description of research group and project

Dr. Linxian Li’s Laboratory has long interests in developing novel biomaterials for clinical applications. Committed to translating new materials for medical use, the Li group focuses on engineering functional materials for medical use and developing biomolecules as therapeutics. We are seeking a highly motivated postdoctoral researcher for research initiatives in polymer chemistry for a wide-array of studies in medicine.

One postdoc position in Polymer Chemistry

We are searching for a postdoctoral researcher with the following qualifications and experience:

  • Applicants must hold a PhD with strong background in Polymer Chemistry.
  • Demonstrated experience in polymer synthesis and characterization.
  • Experience in characterization of polymer libraries will be considered an asset.
  • The ideal candidate should enjoy working in a highly collaborative and interdisciplinary environment.
  • Excellent command of written and spoken English is required.

The employment

This is a one-year fixed-term position, with the possibility of renewal.

The assignment is located at MWLC, Hong Kong, and the employment will follow local labour laws in Hong Kong.

A competitive remuneration package including 10% on top of basic salary (fully-taxable) intended as pension will be offered in addition to MPF employer’s contribution and medical benefits.

Entry requirement

At KI the Postdoctoral researcher position is regarded as an early career step after a doctoral degree. Qualified to be employed as a Postdoctoral researcher is one who has obtained a doctorate or has equivalent scientific competence.

Application process

An employment application must contain the following documents in English:

  1. A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  2. A complete list of publications 
  3. A summary of current work (no more than one page)
  4. Applicants should arrange to have at least two letters of reference

The application is to be submitted through the Varbi recruitment system.

Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.
Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.
Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.
For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.

Type of employmentTemporary position longer than 6 months
Contract typeFull time
First day of employmentAs soon as possible
Number of positions1
Working hours100%
CityHong Kong
Country
Reference number2-2703/2019
ContactLinxian Li, Assistant Professor, linxian.li@ki.se
Last application date02.Jun.2019 11:59 PM CET

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Post expires on Sunday June 2nd, 2019

Postdoctoral researcher in Mitochondrial Biology

Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Division of Molecular Metabolism

Division of Molecular Metabolism
Applications are invited for the postdoctoral position in the group of Joanna Rorbach, at the Division of Molecular Metabolism, Max Planck Institute for Biology of Ageing – Karolinska Institutet Laboratory (MPI-KIL) located at Karolinska Institutet, Stockholm.

 he Division of Molecular Metabolism (http://ki.se/en/mbb/research-divisionof-molecular-metabolism, http://ki.se/en/mbb), is located in Biomedicum, Solna campus of Karolinska Institutet. The research at the division aims at understanding the regulation of mitochondrial function and the role of mitochondrial dysfunction in disease. The current research encompasses biochemical and genetic studies of patients with inherited diseases as well as basic scientific approaches to understand the regulation of mtDNA expression and other aspects of mitochondrial metabolism. The overall aim of the Division of Molecular Metabolism is to combine these different areas of research to get insights into disease pathophysiology and to develop novel treatments.
The Division of Molecular Metabolism offers an outstanding research environment and a close interaction between basic science, clinical science and diagnostics at the Centre for Inherited Metabolic Diseases (CMMS) at Karolinska University Hospital, Stockholm, Sweden. The newly founded Max Planck Institute for Biology of Ageing – Karolinska Institutet Laboratory (MPI-KI laboratory) is also integrated into our laboratory. Excellent access to the most advanced resources in molecular and cell biology is available at the department and at the national core facilities at the Science for Life Laboratory (https://www.scilifelab.se).

Research background
Mitochondria are sub-cellular organelles essential for eukaryotic cell function, and their dysfunction has been implicated in a variety of hereditary diseases, ageing, cancer and immunity. The correct expression of mitochondrial DNA is essential for mitochondrial function. Currently, we try to understand mechanisms of gene expression in mitochondria; as a means to identify the pathways and factors important to human mitochondrial diseases and improve our understanding of the fundamental mechanisms of eukaryotic cell function. More specifically, we focus on: i) RNA-protein interactions in mitochondria; ii) mitochondrial ribosome biogenesis; iii) molecular and structural characterization of the mitochondrial translation machinery. We employ diverse model systems and multidisciplinary approaches and to address these questions, including cryo-EM, high-throughput gene targeting, proteomics and RNASeq-based ribosome profiling.
For further information about the project and the position, please contact Dr Joanna Rorbach, e-mail: Joanna.rorbach@ki.se.

Successful applicant requirements
Enthusiastic and motivated applicants should have a strong background in molecular or structural biology. Specific experience in mitochondrial biology is an advantage, given the nature of the research, but is not a requirement. The successful applicant should be knowledgeable of biological advancements, demonstrate a promising publication record, and have a rigorous scientific approach. The candidate should be able to work independently and interactively in a team and collaborative settings, as our research group collaborates with several laboratories within Sweden and abroad.
A person is eligible for this position, if he or she has obtained a PhD no more than four years before the last date of employment as postdoc. The term can be extended under special circumstances.

Application process
An employment application must contain the following documents in English:

  1. A complete curriculum vitae, including date of the thesis defense, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  2. A complete list of publications
  3. A summary of current work (no more than one page)
  4. Two references (name and contact information)

The application is to be submitted through the Varbi recruitment system.

Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.
Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.
Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.
For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.

Type of employmentTemporary position longer than 6 months
Contract typeFull time
First day of employmentUpon agreement
Salarymonthly
Number of positions1
Working hours100%
CitySolna
CountyStockholms län
CountrySweden
Reference number2-2679/2019
ContactJoanna Rorbach, 08-524 866 93
Union representativeAnne Edgren, OFR/S, P, O, 08-524 87570Biborka Bereczky Veress, SACO, 46 70-173 85 75Henry Wölling, SEKO, 08-524 840 80
Last application date02.Jun.2019 11:59 PM CET

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Post expires on Sunday June 2nd, 2019

Postdoctoral studies in RNA-guided chromatin remodeling and DNA repair

Karolinska Institutet,

The Department of Cell and Molecular Biology (CMB) is a department with a strong focus on basic science. CMB conducts research and education in cell biology, molecular biology, developmental biology, stem cell biology, cancer and infection biology.

Research group
The position is placed in the laboratory of Marianne Farnebo, which currently includes 8 employees – 3 PhD students and 4 postdocs – and locates at the Department of Cell and Molecular Biology (CMB) at Karolinska Institutet. The laboratory studies the function of non-coding RNA and RNA-binding proteins in DNA repair and chromatin remodeling, and how defects in these processes contribute to cancer. A number of cutting-edge techniques required to study RNA are already up and running in Farnebo laboratory, including single-molecule RNA FISH, RNA tethering, live-cell imaging and laser-micro irradiation.

Farnebo laboratory recently moved to Biomedicum, a new interdisciplinary research center designed to concentrate much of the experimental research conducted at Karolinska Institutet Campus Solna under one roof to promote collaboration. Biomedicum will house approximately 1,600 researchers and other personnel and allow expensive equipment to be shared and utilised more effectively.

Description of the Project
Although accumulating evidence reveals that RNA plays a key role in the regulation of chromatin structure, the underlying mechanism(s) remains poorly understood. The postdoc project will focus on characterizing the involvement of RNA and associated proteins in opening and closure of chromatin and in signaling and repair of DNA damage. This project is conceptually novel and expected to have important consequences on our understanding of chromatin integrity control and whether these functions are altered in cancer, which could have implications for cancer therapy.

Qualifications
To build a strong and creative research team, we are looking for high achievers from universities around the world. We will offer an intellectually stimulating environment and we look for talented people who will play a part in developing our next breakthrough ideas. Are you ready to discover the unexplored?

More specifically,

·         Applicant will hold a PhD in Cell Biology, Molecular Biology or Biochemistry

·         Applicant should have previous experience various cell biology techniques, including cell                 culture, microscopy, western blot and cloning.

·         Applicant should have a high personal drive and motivation

·         Applicant should be efficient and contribute productively in a team

·         Applicant should be fluent in English (written and spoken)

·         Emphasis will be placed on personal suitability

Entry requirements
Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.

Applicants who have completed their PhD degree no more than three years before the last date for applications are given priority. 

To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Postgraduates who have yet to graduate may apply if their public defense is scheduled to take place within three months after the application deadline.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Type of scholarship
The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

The scholarships may be paid by Radiumhemmets Forskningsfonder.

Application process
An application must contain the following documents in English:

1.       Curriculum vitae
2.       A complete list of publication
3.       A personal letter
4.       Copy of university and high school/gymnasium transcripts and final grade scores

Deadline for applications is 10 May 2018, but interesting candidates can be called for interviews before this deadline so applying before the deadline is encouraged.

The application is to be submitted on the Varbi recruitment system.

Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.
Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.
Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.
For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.

Reference number2-2285/2019
ContactMarianne Farnebo, Associate Professor, , Marianne.Farnebo@ki.se
Last application date10.Jun.2019 11:59 PM CET

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Post expires on Monday June 17th, 2019

Postdoctoral studies in Epigenetic regulation of hematopoietic stem cells (Scholarship)

Karolinska Institutet, The department of Medicin, Huddinge

Division
The Department of Medicine at Huddinge comprises seven units, three research centers and, around 60 independent research groups. The Center for Hematology and Regenerative Medicine (HERM) is a research unit within the Department of Medicine Huddinge which brings together basic and clinical research competences to pursue cutting-edge research improving the understanding of mechanisms involved in normal and malignant hematopoiesis (https://ki.se/en/medh/center-for-hematology-and-regenerative-medicine).

Description of the research group and project
Dr. Sidinh Luc is an Assistant Professor at the Center for Hematology and Regenerative Medicine (HERM), at the Institute of Medicine, Huddinge (MedH), Karolinska Institutet (https://ki.se/en/medh/sidinh-luc-group). Her research group consists of 4 people and is now expanding with a senior scientist within the molecular biology field.

Dr. Luc was recruited from Boston Children’s Hospital/Dana-Farber Cancer Institute/Harvard Medical School to establish her research group and research program at HERM. The group is in a highly interactive research environment within cellular and molecular regulation of hematopoiesis that includes both preclinical and clinical research groups. The research focus of the Luc laboratory is to study the function and epigenetic regulation of hematopoietic stem cells in normal development using genetic mouse modeling, and cell and molecular biological methods on small cell numbers and single cell analyses (Luc et al., Cell Rep. 2016 Sep 20;16(12):3181-94; Luis and Luc et al., Nat Immunol. 2016 Dec;17(12):1424-1435. The project focus is to study the role of epigenetic regulators important for HSC lineage commitment using mouse modelling techniques.

Description of the position
Applicants are invited to submit applications for a two-year postdoctoral scholarship position, with an initial fixed term of one year, and with the possibility of a one-two-year extension (i.e. up to 2+2 years).

You will lead the research activity of the project(s) from beginning to end. Research activities involve experimental work in molecular biological assays, flow cytometry and in vivo mouse experiments. Due to the complexity of the research, the research activities are done in close collaboration with other lab members as well as collaborators within and outside of Karolinska Institutet.

Key responsibilities

  • Organize, plan, perform and analyze experimental work
  • Contribute with molecular biology or cellular biology expertise and leadership to junior members of the laboratory
  • Work closely with other lab members on experimental work conducted in the laboratory
  • Function as the lead contact with collaborators within and outside of Karolinska Institutet

Entry requirements
We are seeking a motivated, responsible and results-driven researcher with a Ph.D. degree in the molecular biology or cell biology fields, to drive a new and exciting project within molecular regulation of hematopoiesis. The applicant can have a scheduled date for PhD-dissertation (in the mentioned subjects). In the latter case, however, the postdoc position can only be approved once the doctoral degree has been awarded. The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish PhD or higher.

Essential requirements

  • PhD degree, or PhD-dissertation scheduled, in which the latter require case verification from the Dissertation Committee (or equivalent body)
  • Good proficiency of spoken and written English
  • Strong organizational skills
  • Strong interpersonal skills, including written and oral communication
  • Ability to work in a fast-paced and quickly changing environment
  • Goal-oriented and performance-driven

Desired requirements

  • Experience with mouse work (Function A, Felasa B)
  • Experience in hematopoiesis or immunology
  • Experience with next-generation sequencing analysis including RNA-seq and ATAC-seq, ChIPseq

Personal suitability will be a strong selection criterion.

Application process
The application must contain the following documents in English:

  1. Cover letter, including a summary of the Ph.D. studies (no more than two pages).
  2. A complete Curriculum Vitae, including date of the thesis defense, title of the thesis, previous academic positions, academic title, current position and academic distinctions.
  3. A complete list of publications.
  4. Verification from the thesis defense committee or the equivalent (only applicable if a PhD degree has not yet been obtained).
  5. Names and contact details of three references who are familiar with the applicants recent research and training.

The application is to be submitted on the Varbi recruitment system.

Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.
Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.
Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.
For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.

Type of employmentPostdoctoral scholarship
Contract typeFull time
First day of employmentAccording to agreement
Number of positions1
Working hours100 %
CityHuddinge
CountyStockholms län
CountrySweden
Reference number2-2897/2019
Contact Sidinh Luc, Sidinh.luc@ki.se
Union representative Belinda Pannagel, SACO, Belinda.pannagel@ki.seCarina Eklund, OFR, Carina.eklund@ki.se
Last application date15.Jun.2019 11:59 PM CET

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Post expires on Monday June 17th, 2019

Postdoctoral Researcher in the functional metabolic profiling of lipid mediators in lung disease

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Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Chemistry II

The project: We have an opening for an individual wishing to join a multidisciplinary project aimed to understand the role of lipid mediators in obstructive lung disease. Chronic lung disease is one of the largest noncommunicable diseases globally, with 4 million deaths in 2012 alone. The successful candidate will be expected to use and further develop mass spectrometry-based methods for metabolic profiling of lipid mediators (e.g., prostaglandins, leukotrienes, oxylipins) and related molecules in a range of biological matrices. Analyses will involve development of novel chromatography approaches including chiral and UPC2 methods for applications in clinical cohorts as well as experimental models to map the biochemical role of lipid mediators in the pathobiology of inflammation. Functional studies will be performed in multiple cell types, in ex vivo lung tissue as well as in animal models to generate a biochemical map of both pro-inflammatory and pro-resolving lipid mediators. The identified lipid mediator profiles will be used to guide systems medicine-based studies to stratify patients in order to understand the mechanisms driving this heterogeneous disease, with the aim of identifying sub-phenotypes to inform patient diagnosis and treatment strategies.

The Environment: The successful applicant will belong to the Integrative Molecular Phenotyping laboratory (http://metabolomics.se) in the Department of Medical Biochemistry and Biophysics. The Karolinska Institute is one of the world´s leading medical universities. Its mission is to contribute to the improvement of human health through research and education. The Karolinska Institute accounts for over 40 per cent of the medical academic research conducted in Sweden and offers the country´s broadest range of education in medicine and health sciences. Since 1901 the Nobel Assembly at the Karolinska Institute has selected the Nobel laureates in Physiology or Medicine. The research environment includes working with state-of-the-art equipment, including multiple mass spectrometers in a new custom designed state-of-the art facility. This full-time position is temporary (two years), with potential for renewal for at least 2 more years.

Qualifications: We are looking for highly motivated candidates with a Ph.D. in quantitative mass spectrometry or bioanalytical chemistry. The successful candidate will be expected to use and further develop mass spectrometry-based methods for metabolic profiling of lipid mediators. Accordingly, applicants need to document their experience in small molecule mass spectrometry by LC-MS/MS. We are especially interested in candidates with prior experience working with eicosanoids or other bioactive lipid mediators in inflammatory systems. Experience in cell culture and FACS analysis would be a significant merit as is experience with multivariate statistics, biomedical training, clinical research or studies of metabolism. Excellent communication skills and an ability to interact socially and scientifically with other members of the laboratory and with collaborators in various networks are essential. Previous post doc experience and a strong publication record are also strong merits.

Entry requirements: A person is eligible for a position as Postdoctoral Researcher if she or he has obtained a PhD or a foreign qualification deemed equivalent to a doctorate, no more than five years before the last date of employment as postdoc. Applicants who have completed their degree no more than three years before the last date for applications will be given priority.

The start date is negotiable, but the selected candidate would ideally begin in August 2019. Applications will be evaluated as they are received.

The application is to be submitted through the Varbi recruitment system.

Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.
Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.
Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.
For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.

Type of employmentTemporary position longer than 6 months
Contract typeFull time
First day of employmentUpon agreement
Salarymonthly
Number of positions1
Working hours100%
CitySolna
CountyStockholms län
CountrySweden
Reference number2-2588/2019
ContactCraig Wheelock, +46 8-524 876 30
Last application date26.May.2019 11:59 PM CET

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Post expires on Sunday May 26th, 2019

Postdoc position, Maintenance of neuronal identity

Karolinska Institutet,

The Department of Cell and Molecular Biology (CMB) is a department with a strong focus on basic science. CMB conducts research and education in cell biology, molecular biology, developmental biology, stem cell biology, cancer and infection biology.

Division
The research group of Johan Holmberg is part of the Department of Cell and Molecular Biology (CMB) which recently moved to the new interdisciplinary research centre Biomedicum located at Campus Solna, Karolinska Institutet.

Background
The brain contains a large number of different neuronal subtypes that maintain their distinct identities over several decades despite continuous environmental fluctuation. Apart from the instructive information provided by transcription factors controlling cell type specific transcriptional programs, there is presumably also a need to maintain silencing of alternative transcriptional programs. The mechanisms governing permanent repression of aberrant transcription in mature neurons are not well understood. Our lab focuses on the role of repression of alternative gene programs for lifelong maintenance of serotonergic and dopaminergic identity. For a more extensive background see: Holmberg and Perlmann, Nature Review Genetics 2012 and Södersten, E. et al. Nature Commun. 2018. Besides exploring fundamental processes we also aim to understand how they influence clinically relevant topics including psychiatric disorders, neurodegeneration and aging. The group also harbour an interest in the understanding of the paediatric malignancy, neuroblastoma, see: Westerlund, et al. Proc Natl Acad Sci U S A 2017.

In this project we will generate and analyse large amounts of data from defined wild type/mutant mouse neuronal populations in order to understand the functional relevance of gene repression for safeguarding mature serotonergic and dopaminergic identity.

Position specific requirements
We are looking for an outstanding researcher able to analyse and integrate large sets of bulk and single cell RNA-seq with ChIP-seq data generated from restricted in vivo neuronal subpopulations. Additional experience with confocal image acquisition and analysis as well as with in vivo/in vitro standard methods (e.g. immunostaining, FACS, stereotactic injections, behavioural analysis and cell culture) will be considered as a distinct advantage. Thus we are primarily looking for a computational biologist with experience/interest in laboratory/animal work or an experimental biologist with extensive bioinformatic skill and interest.

The applicant must be able to communicate well in English.

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Type of scholarship
The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process
An application must contain the following documents in English or Swedish:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • Cover letter stating the motivation to apply and key skills that match the profile 

The application is to be submitted on the Varbi recruitment system.

Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.
Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.
Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.
For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.

First day of employmentas soon as possible
Reference number2-2626/2019
ContactJohan Holmberg, johan.holmberg@ki.se
Last application date31.May.2019 11:59 PM CET

Read the job description at the university homepage

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Post expires on Friday May 31st, 2019

Postdoctoral studies in tumor and vascular biology (scholarship)

Karolinska Institutet, Department of Oncology-Pathology, Group Holmgren

At the Department of Oncology-Pathology basic, translational and clinical research and educational activities related to cancer is carried out. Approximately 300 people from over 40 nations are currently working at the department. About 30 research groups with various cancer research profiles are involved and we have around 110 PhD students. The Department of Oncology-Pathology is responsible for undergraduate courses in Pathology, Oncology and Forensic Medicine for medical students, as well as for Tumor biology courses for biomedicine students and Pathology courses for opticians.

Division
The position is placed in the research group of Prof. Lars Holmgren, in the new research building Bioclinicum.

Project background
Mechanical forces control the development of functional organs but are also deregulated in tumor progression and vascular disease. To date, we know very little regarding the molecular pathways by which cells respond to force and how these can be used for therapeutics. We have previously reported the discovery of the Angiomotin protein family (Troyanovsky JCB 2001, Aase Genes&Development 2007, Yi Cancer Cell 2011, Hultin Nature Comm 2014, Mojallal Nature Comm 2014, Zheng Scientific Reports 2016). We have shown that these proteins relay force by connecting membrane receptors to the cytoskeleton. We further showed relevance for these proteins in essential developmental processes such as angiogenesis, blastocyst hatching and aortic expansion. Our present research deals with how mechanical forces contribute to malignant progression as well as vascular inflammation.
See more info:
http://ki.se/ki/jsp/polopoly.jsp?l=en&d=10258&a=130074

Area of responsibilities/description of the work
The successful applicant will join a team consisting of post-docs, PhD students and master students. The projects include understanding how mechanical forces are transmitted between cells and into the nucleus. These processes are coupled to human disease and we collaborate with pathologists and clinicians to translate our findings to clinically applicable results. The team also collaborates with the Sci-Life facility for drug screenings, proteomics and RNA seq analysis. Lars Holmgren´s group is now situated in the new Bioclinicum building with over 900 researchers in oncology, cardiology, inflammation and neurology. The theme of cancer is now emerging as one of Europe’s strongest research environments with proximity to the oncology clinics and clinical trial center as well as basic scientists at the Biomedicum center.    

Entry requirements
Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate.
The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Type of scholarship
The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Qualifications
To qualify, the applicant must hold a doctor’s degree or a foreign qualification deemed equivalent to a doctorate in a relevant field. The applicant must have more than 3 years of experience in experimental research and be well educated in the areas of developmental biology, tumor biology, confocal imaging.

The position will be fixed to one year with possibilities for prolongation with one more year. Applicants will be evaluated on the following criteria:

1)  Education and previous training
2)  Relevance for the project
3)  Publication and track record
4)  Motivation

Application process
An employment application must contain the following documents in English or Swedish:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system. Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.
Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.
Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.

For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.

Login and apply

Read the job description at the unviersity homepage

First day of employmentAccording to agreement
Reference number2-1964/2019
ContactLars Holmgren, 08 517 793 17, lars.holmgren@ki.se
Union representativeAndreas Lundqvist, SACO, 08 517 768 84Helen Eriksson, OFR, 08 517 762 79
Last application date28.May.2019 11:59 PM CET

Post expires on Tuesday May 28th, 2019

Postdoctoral Researcher in Chemistry or Materials Science

Ming Wai Lau Centre for Reparative Medicine, KI, Hong Kong

Ming Wai Lau Centre for Reparative Medicine (MWLC) aims to contribute to the improvement of human health by conducting cutting-edge research in reparative medicine and related subjects, by creating a new platform for synergies between academia and innovation in Sweden and Hong Kong as well as China, and fostering future leaders in both academia and industry.

For more information, please visit ki.se/mwlc

Description of research group and project

The current research of Assistant Professor Sijie Chen aims at developing novel fluorescence based tools and technology for biological research, especially mechanobiology studies.

One position as postdoctoral researcher are available in the following areas: Fluorescent biosensors, materials science, chemistry

Qualifications

We are looking for a highly-motivated, creative researcher, who enjoys an interdisciplinary, open and collaborative environment, with the following qualifications, experience and skills: 

  • Completion of a PhD or an equivalent degree in chemistry, materials science or related disciplines.
  • A strong publication record in peer reviewed journals.
  • Knowledge of fluorescence, fluorescent probes and fluorescence based techniques. 
  • Experience and expertise in chemical synthesis, materials, biomaterials, and materials characterization, and/or fluorescent materials/sensors, and spectroscopy.
  • Experience in super-resolution microscopy, atomic-force microscopy, FLIM, is an advantage.
  • Excellent written and oral communication skills in English.

 The employment

This is a two-year full-time position, with the possibility of renewal.

The assignment is located at MWLC, Hong Kong, and the employment will follow local labour laws in Hong Kong.

A competitive remuneration package including 10% on top of basic salary (fully-taxable) intended as pension will be offered in addition to MPF employer’s contribution and medical benefits.

Entry requirement

Qualified to be employed as a Postdoctoral researcher is one who has obtained a doctorate or has equivalent scientific competence.

Application process

An employment application must contain the following documents in English:

  1. A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  2. A complete list of publications
  3. A summary of current work (no more than one page)
  4. Applicants should arrange to have at least two letters of reference

The application is to be submitted through the Varbi recruitment system.

Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.
Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.
Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.

For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.

Read the job description at the universtiy homepage

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Type of employmentTemporary position longer than 6 months
Contract typeFull time
First day of employmentAs soon as possible
Number of positions1
Working hours100%
CityHong Kong
CountryHong Kong
Reference number2-1325/2019
ContactSijie Chen, Assistant Professor, sijie.chen@ki.se
Last application date15.Apr.2019 11:59 PM CET

Post expires on Monday April 15th, 2019