Tag-arkiv: Karolinska Institutet

Postdoctoral studies in Basic and Clinical Muscle Biology (scholarship)

Karolinska Institutet,

At the Department of Physiology and Pharmacology we teach and conduct internationally acclaimed, high-quality research in Physiology, Pharmacology, Anesthesiology and Intensive care. We have around 400 employees, 30 research groups, and 90 doctoral students. Our research fields include cellular signaling, cardiovascular and respiratory systems, neuropsychopharmacology, neuroinflammation, pharmacogenetics, regenerative medicine, Renal System, anesthesiology and intensive care, muscle physiology and pain. Our collaboration with the clinics at Karolinska University Hospital provides unique opportunities for translational research within our subjects. More information about research at http://ki.se/fyfa_english

Division
Basic and Clinical Muscle Biology group:Regulation of muscle contraction at the cell and motor protein levels are investigated in both health and disease in experimental and clinical studies. Currently, there is a specific focus on the mechanisms underlying the impaired skeletal muscle function in intensive care unit (ICU) patients exposed to long term mechanical ventilation and immobilization, i.e., the critical illness myopathy (CIM) and the ventilator induced diaphragm muscle dysfunction (VIDD).  This research is aiming at: (a) unravelling underlying mechanisms, (b) improve diagnosis/monitoring and (c) introduce specific intervention strategies targeting underlying mechanisms.

Duties
Participate in long-term experimental ICU studies involving extensive monitoring. Analyses of regulation of muscle contraction at the cell and motor protein levels. Participate in clinical studies on mechanically ventilated ICU patients.

Entry requirements
Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Type of scholarship
The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process
An employment application must contain the following documents in English or Swedish:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system. Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.
Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.
Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.

For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.

First day of employmentEnligt överrenskommelse
SalaryStipendium
Reference number2-7292/2018
Contact Lars Larsson, professor/överläkare, 08-524 872 95, lars.larsson@ki.se
Union representativeBo Rydqvist, SACO, 08-524 872 67, bo.rydqvist@ki.seNiklas Andersson, OFR, niklas.andersson@ki.seHenry Wölling, SEKO, henry.wolling@ki.se
Last application date08.Feb.2019 11:59 PM CET

Login and apply


Read the job description at the university homepage

Post expires on Friday February 8th, 2019

Postdoctoral studies in RNA biology and chromatin remodeling

Karolinska Institutet,

The Department of Cell and Molecular Biology (CMB) is a department with a strong focus on basic science. CMB conducts research and education in cell biology, molecular biology, developmental biology, stem cell biology, cancer and infection biology.

Division
The scholarship position is placed in the laboratory of Marianne Farnebo, which currently includes 8 employees – 3 PhD students, 4 postdocs and a lab manager – and locates at the Department of Cell and Molecular Biology (CMB) at Karolinska Institutet. The laboratory studies the function of non-coding RNA and RNA-binding proteins in DNA repair and chromatin remodeling, and how defects in these processes contribute to cancer. A number of cutting edge techniques required to study RNA are already up and running in Farnebo laboratory, including single-molecule RNA FISH, RNA tethering, live-cell imaging and laser-micro irradiation. 

Farnebo laboratory recently moved to Biomedicum, a new interdisciplinary research center designed to concentrate much of the experimental research conducted at Karolinska Institutet Campus Solna under one roof to promote collaboration. Biomedicum will house approximately 1,600 researchers and other personnel and allow expensive equipment to be shared and utilised more effectively.

Duties/Description of the project
Although accumulating evidence reveals that RNA plays a key role in the regulation of chromatin structure, the underlying mechanism(s) remains poorly understood. The postdoc project will focus on characterizing the involvement of RNA in the assembly and disassembly of chromatin and whether these functions are altered in cancer cells, which could have implications for cancer therapy. This project is conceptually novel and expected to have important consequences on our understanding of chromatin structure control and on downstream cellular functions, like transcription and DNA repair.

Qualifications
The successful applicant will hold a PhD in Cell Biology, Molecular Biology or Biochemistry. He/she should also have previous experience in molecular mechanisms of noncoding RNAs and/or chromatin functions and relevant techniques. Experience in biochemical approaches such as assaying chromatin assembly and analyzing phase separation in vitro is a strong merit.

To build a strong and creative research team, we are looking for high achievers from universities around the world. We will offer an intellectually stimulating environment and we look for talented people who will play a part in developing our next breakthrough ideas. Are you ready to discover the unexplored?

More specifically,

  • Applicant should have a high personal drive and motivation
  • Applicant should have innovative thinking and be eager to solve problems
  • Applicant should be efficient and able to contribute productively in a team
  • Applicant should be fluent in English (written and spoken)
  • Emphasis will be placed on personal suitability

Entry requirements
Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate.
The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Type of scholarship
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.
The scholarships may be paid by Radiumhemmets Forskningsfonder.

Application process
An application must contain the following documents in English:

  1. Curriculum vitae and qualifications
  2. A complete list of publications
  3. A summary of current work (no more than one page)
  4. A personal letter
  5. Copy of university and high school/gymnasium transcripts and final grade scores

Deadline for applications is November 30, 2018, but interesting candidates can be called for interviews before this deadline so applying before the deadline is encouraged.

The application is to be submitted on the Varbi recruitment system. Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.
Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.
Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.

For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.

First day of employmentStarting fall-winter 2018
Reference number2-4559/2018
Contact Marianne Farnebo, Associate Professor, marianne.farnebo@ki.se
Last application date31.Jan.2019 11:59 PM CET

Login and apply

Read the job description at the university homepage

Post expires on Thursday January 31st, 2019

Postdoctoral studies in project focused on dopamine neurons, stem cells and regenerative medicine (scholarship)

Karolinska Institutet,

The Department of Cell and Molecular Biology (CMB) is a department with a strong focus on basic science. CMB conducts research and education in cell biology, molecular biology, developmental biology, stem cell biology, cancer and infection biology.

Division
A postdoctoral position is available in the lab of Thomas Perlmann at the Department of Cell and Molecular Biology at Karolinska Institutet, one of the world´s leading biomedical research institutes. The lab is located at Biomedicum, a newly opened research building with excellent infrastructure and world leading research. Our primary focus is on the development of dopamine neurons and the ventral midbrain region where dopamine neurons are generated. We are unraveling the signaling and transcriptional regulation that govern the specification, differentiation and maintenance of these cells. The studies have resulted in the identification of several transcription factors with key roles in these processes. Moreover, we are also interested in regenerative medicine in relation to Parkinson´s disease and other brain disorders. We are using mouse genetics and methods such as single cell RNA sequencing in our studies. In collaborative projects we also focus on regenerative strategies such as stem cell therapy, and on the maintenance of dopamine neurons in the human brain.

Duties
We now have an opening for a postdoc in projects devoted to questions concerning the potential for neurogenesis of dopamine neurons in the adult brain, development and subtype specification of dopamine neurons, and mechanisms underlying aging and dopamine neuron maintenance.

Entry requirements
The applicant should be a highly motivated scientist who can collaborate, communicate and function well in a team. We are looking for an individual with a PhD in neuroscience, stem cells or developmental biology, and with skills preferably in more than one of the following areas: human embryonic stem cells, mouse genetics, bioinformatics and histological methods.

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.

A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Type of scholarship
The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process
An employment application must contain the following documents in English or Swedish:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system. Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.
Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.
Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.

For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.

Reference number2-7414/2018
ContactThomas Perlmann, , Thomas.Perlmann@ki.se, www.perlmannlab.org
Union representativeMagnus Anå, OFR, 08-524 864 37, magnus.ana@ki.seBiborka Bereczky Veress, SACO, 46 70-173 85 75 , biborka.bveress@ki.seElisabeth Valenzuela, SEKO, 08-524 863 53, elisabeth.valenzuela@ki.se
Last
application
date
31.Jan.2019 11:59 PM CET

Login and apply

Read the job description at the university homepage

Post expires on Thursday January 31st, 2019

Postdoctoral Researcher in Biostatistics

Karolinska Institutet, MEB

The Department of Medical Epidemiology and Biostatistics (MEB) is among the largest departments of epidemiology in Europe with special focus on increasing our knowledge of the aetiology of different diseases. Our department consists of researchers, doctoral students, biostatisticians, data collectors and database administrators as well as administrative personnel, in total some 250 staff. The department is situated at campus Solna. Further information can be found at ki.se/meb

Division
A two-year postdoctoral research position (with the possibility for extension) is available within the biostatistics group at the Department of Medical Epidemiology and Biostatistics at Karolinska Institutet, Stockholm. The biostatistics group comprises 4 professors, 5 senior researchers, 5 assistant professors, 3 post-docs, 16 Ph.D. students and 9 applied statisticians.

Members of the Biostatistics group conduct methodological research in a broad range of areas, including surrogates, causal inference, clinical trials, epidemiological methods, registry-based analysis methods, image analysis, flexible survival analysis, statistical genetics, and joint modeling of longitudinal data. The group collaborates within the department and with groups world wide on cancer treatment and diagnosis, psychiatric disorders, aging, transfusion medicine and HIV treatment.

Duties
A successful applicant will work on the development of retrospective study design from an existing HIV registry to investigate the, potentially causal, relationship between HIV treatment and markers of premature aging. Methodological development may be required in both the design and analysis of the resulting data, due to the incredibly complex system of biological mechanisms and inherent survivor bias.

Entry requirements
To be able to be employed as a post-doctoral researcher you have to have obtained a doctorate or have equivalent scientific competence, no more than three years before the last date of application (the term can be extended under special circumstances, such as sick-leave or parental leave. Reason, dates and extent must be clearly specified in the application and verified with relevant documentation).

The position requires a Ph.D. degree with a focus on statistics, biostatistics, or a closely related field. Experience in HIV research, observational study design for causal inference and mediation analysis are desirable. The applicant should have a strong interest in both methodology development and in applications.

Candidate should be able to work independently or as part of a group and must be able to collaborate with researchers from other disciplines. Candidate should have the ability to focus on a single goal without distraction when needed, but be curious and investigate alternatives when time allows.

Application process
An employment application must contain the following documents in English or Swedish:

  1. A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  2. A complete list of publications
  3. A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system. Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.
Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.
Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.

For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.

Type of employmentTemporary position longer than 6 months
Contract typeFull time
First day of employmentAccording to agreement
SalaryMonthly
Number of positions1
Working hours100%
CityStockholm
CountyStockholms län
CountrySweden
Reference number2-7222/2018
Contact Erin Gabriel, erin.gabriel@ki.seLina Werner, lina.werner@ki.se
Union representative Ulrika Zagai, SACO, ulrika.zagai@ki.seAnn Almqvist, OFR, ann.almqvist@ki.seHenry Wölling, SEKO, henry.wolling@ki.se
Last application date01.Feb.2019 11:59 PM CET

Read the job description at the university homepage

Login and apply

Post expires on Friday February 1st, 2019