Do you want to contribute to top quality medical research?

We are looking for 1-2 Postdoctoral Researcher(s) (Scholarship) with an interest in Adoptive Cell Therapy and how it can be used as treatment. When joining our team, you will work in a research group conducting translational research, with an aim to improve cell therapy for patients with gynecological cancer or melanoma.

Division:

You would join the Stina Wickström/ Rolf Kiessling research team with a focus on improving existing and developing new novel T cell products used for adoptive cell therapy to treat patients with gynecological cancer or melanoma.

Duties

We are looking for 1-2 highly motivated person(s) with a strong background in immunology and tumor biology. The projects involve the development of human T cell technologies and evaluation of T cells from blood/tumor tissue from cancer patients, T cell repertoires and T cell function. The overall aim of the projects is to develop novel immunotherapies against cancer. Your daily work would include, primary cell culture, FACS analysis, functional T cell assays, sample collection etc.

Entry requirements

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Qualifications:

• The applicant must show verified skills particularly in in tumor immunology and immunotherapy of cancer and methodological expertise with a focus on human cellular immunology research.
• Fluency in English is a requirement.
• The candidate should be self-motivated.
• Have good communication skills.
• Ability to interact effectively and work within a team.

Location: Solna

The position will either be at Karolinska Insitutet or at Radiumhemmets forskningsfonder with an affiliation to Karolinska Insitutet.

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system at the latest 28^th February. 

Want to make a difference? Join us and contribute to better health for all

Deadline: 2024-02-28 at 23:59
Unit: Forskargrupp Hartman

Read the job description at the university homepage or apply.

Do you want to contribute to top quality medical research?

We are seeking a highly skilled and motivated post-doctoral research fellow in protein production/structural biology, to join an international open science project in translational medical research. The project aims to investigate under-studied human genes as potential drug targets through generation of open-access knowledge and high-quality research tools. This is an exciting opportunity to work on producing and characterizing novel human proteins as well as recombinant antibodies to human targets as part of the EUbOPEN project, using a combination of molecular biology, biochemistry and structural biology. We offer a multi-national and collaborative research environment with partners in academia and the biomedical industry worldwide.

Your mission

A highly motivated, skilled and experienced post-doctoral research fellow in protein production/structural biology is needed to work at SGC-Karolinska in our IMI (EU and Pharma) funded EUbOPEN project. You will be part of a collaborative research environment, driving the characterization of human disease-linked genes at the protein level: developing or implementing expression and purification strategies, characterizing the proteins biophysically and biochemically, developing activity assays and supporting the development of antibody and/or small-molecule reagents. For selected targets you will pursue structural studies. Your work will involve a variety of target classes, with a focus on inflammation and autoimmunity-related targets.

The duties of the position also include reporting and data dissemination (via publications and public data repositories). Thus, your work will contribute to the broader goal of EUbOPEN; to make pharmacological tools to one third of the human druggable genome available to the scientific community without restrictions, as part of the Target 2035 initiative.

Project:

This large-scale project is a collaboration between Karolinska Institutet, University of Oxford (UK), Goethe University Frankfurt and other partners in EU, UK and globally, funded by the European Union and pharmaceutical company partners. EUbOPEN is conducted as an integrated project with the Structural Genomics Consortium (SGC). The EUbOPEN organization based at Karolinska Institutet comprises funding for more than 20 staff members and is expected to grow as additional funding becomes available. Overall, EUbOPEN has activities e.g. in structural and chemical biology, antibody production and characterization as well as functional studies of human proteins in disease relevant assays. EUbOPEN is funded until end of April 2025 and the right candidate will have a good chance of extension

Your profile

You have a recent PhD degree in medicine/biomedicine, molecular biology, protein biochemistry, structural biology, cell biology or other relevant area(s) and a passion for practical laboratory work. You are a flexible problem solver who likes to work collaboratively as well as independently with production, analysis and reporting of data to the project team. Experience from designing and running biochemical assays and characterization of proteins is a merit. Furthermore, you need to be able to communicate well in English, be well-structured and take responsibility to produce well-documented high-quality scientific data.

You should have documented experience with protein production and purification. Experience with structural biology is a distinct merit and experience in the design and selection of optimal expression systems is an advantage.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location

The position is located within the Department of Medicine, Solna. The department consists of twelve divisions and each division consists of several research groups. The position is located within the research group of Michael Sundström, within the Department of Medicine Solna which since March 2015 is one of the partners of the Structural Genomics Consortium (SGC, www.thesgc.org) and its Innovative Medicines Initiative (EU) projects which in part focus on the discovery and evaluation of novel targets in inflammatory diseases (ULTRA-DD 2015-2020 and EUbOPEN 2020-2025, www.eubopen.org). The position is placed within the SGC-KI research team headed by Michael Sundström (Scientific Director) and directly supervised by Dr. Opher Gileadi, Division of Rheumatology, Department of Medicine, Karolinska Institutet, Solna.

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2024-02-27 at 23:59
Unit: Forskargrupp Hartman

Read the job description at the university homepage or apply.

Do you want to contribute to better health for all?

The Department of Global Public Health is a multidisciplinary department with the aim to advance knowledge about challenges and opportunities for public health in a local, national, and global setting. Research at the department is focused on how different societal and individual factors affect population health, and to develop and evaluate structural and individual-oriented interventions. Many researchers at the department are scientific advisors to authorities and other decision makers at regional, national, and international levels. The department has 12 research groups, about 110 PhD students and about 140 employees.

This position is located in the research group Epidemiology of Psychiatric Conditions, Substance use and Social environment (EPiCSS). The aim of EPiCSS is to develop early interventions and prevent mental illness, including substance use, by understanding risk and protective factors.

Your mission

We are looking for a postdoc to the research group EPiCSS with an interest in and expertise in psychiatric epidemiology, to work within a FORTE-financed project focusing on how migration affects compulsory psychiatric care using regional and national registers.

The aim is to study why compulsory psychiatric care is more common amongst migrants than the Swedish-born population and examine possible explanations as to why it differs. This will be done using register based epidemiology.

The main task is the production of scientific articles for publication. The applicant is expected to plan and perform statistical analyzes, present at conferences and participate in writing research applications. Furthermore, the applicant is expected to conduct some teaching and supervision.

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

We are looking for a motivated researcher with a background in and knowledge of register based psychiatric epidemiological research. Furthermore, very good English skills in speaking and writing are an absolute requirement for the position. Good statistics skills (SAS / Stata / SPSS) are also a requirement. The applicant must have experience in independently analyzing large databases. Of importance is the applicant’s prior scientific publication. Experience in registry research, and research in psychiatric epidemiology and research of migration and knowledge in the Swedish health care system will be considered an advantage. The applicant should be collaborative and have good communication skills.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna, Torsplan

Read more about the Department of Global Public Health (GPH)

Read more about EPiCCS research group  

Read more about the project you will be working on

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply at the latest 1st March 2024. 

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2024-03-01 at 23:59
Unit: Forskargrupp Hartman

Read the job description at the university homepage or apply.

Do you want to contribute to top quality medical research?

Description of the research group

Kasper Lab. With our research – rooted within the fields of skin and stem cell biology – we aim to answer fundamental questions about tissue homeostasis, repair, and regeneration. We use modern techniques such as single-cell RNA-sequencing, in vivo lineage-tracing, spatial mapping in situ and computational biology, to uncover the cellular behavior and molecular signals of individual cells in skin during health, injury repair and cancer development (key lab references: Joost et al. Cell Stem Cell 2020; Sun et al. eLife 2020; Cockburn et al. Nature Cell Biology 2022; Jacob et al. Developmental Cell 2023). We are a young and dynamic research team with a well-established collaborative network (http://kasperlab.org). The group is placed in Biomedicum, a top modern research building with a large repertoire of researchers and technologies including activities in forefront single-cell omics, mouse work, FACS and high-end microscopy.

Your mission

The major goal is to explore the importance and interplay of the rich variety of cell types and states in the skin. For example, how do the various skin cell types regulate epidermal turnover and differentiation, and what are key-regulatory molecular processes that maintain health and trigger disease? The successful candidate will explore human and mouse skin using a wide variety of state-or-the-art technologies such single-cell RNA sequencing, in vivo lineage tracing and targeted cell ablation, confocal microscopy, organoid culture, and tissue engineering. The successful candidate is expected to independently plan and coordinate scientific projects, actively engage in writing grant applications and in supervising students within the Kasper lab.

 Your profile

We are seeking a highly motivated researcher with a good team spirit and deep curiosity for science. The ideal candidate should have a strong background in molecular or cell biology, with a keen interest in tissue stem cell biology and cell-differentiation processes. Experience in working with primary tissue and mouse models, molecular biology techniques, microscopy, skin biology, and alternative splicing are a plus, and an excellent ability to communicate in English (written and verbal) are a requirement. A proven track record in molecular, cell, or tissue biology demonstrating high-quality research in international journals is a merit. Emphasis will also be placed on personal suitability, complementary, and interactions with current lab members.

Entry requirements

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Location: Stockholm

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A personal letter of motivation
• A complete list of publications
• A summary of current work (no more than one page)
• Two reference persons

The application is to be submitted on the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2024-02-26 at 23:59
Unit: Forskargrupp Hartman

Read the job description at the university homepage or apply.

Do you want to contribute to top quality medical research?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

Aging Research Center (http://ki-su-arc.se/) is one of the divisions at the NVS Department, located at KI campus Solna. The Aging Research Center is a multidisciplinary academic environment, representing psychology, sociology, and various branches of medicine (e.g., neurology, epidemiology, and psychiatry). In the psychology sector of the center, we examine brain correlates of cognitive aging and seek to understand how genetic and lifestyle factors shape development of brain and cognition in adulthood and old age. We approach these research questions with small-scale neuroimaging studies, large-scale intervention (e.g., training) studies, and large-scale population-based longitudinal studies. Our research group consists of senior researchers, postdocs, and doctoral students.

The doctoral student project and the duties of the doctoral student

Episodic memory, our long-term memory of specific events, declines with age and shows large inter-individual differences. The hippocampus is crucial for the encoding, consolidation, and retrieval of episodic memories. Meanwhile, adult neurogenesis, the formation of new neurons, occurs in the dentate gyrus of the hippocampus and also declines with advancing age. Animal data have shown that hippocampal neurogenesis is crucial for two cognitive processes key to episodic memory: pattern separation, which prevents confusion between similar memories, and reactivation, which supports consolidation. Additionally, neurogenesis is important for mental health, specifically depression. However, data in humans are lacking due to the difficulty of measuring neurogenesis non-invasively. Due to groundbreaking developments in magnetic resonance imaging, it has very recently become possible to detect the neurogenic signal in vivo.

The current doctoral project will be led by Principal Researcher Goran Papenberg (main supervisor, https://ki.se/en/people/goran-papenberg). The work will be conducted in close collaboration with Principal Researcher Marc Guitart-Masip (https://ki.se/en/people/marc-guitart-masip) and Assistant Professor Bárbara Avelar Pereira (https://ki.se/en/people/barbara-avelar-pereira) who will serve as co-supervisors for the selected candidate.

In the current project, the student will combine behavioral neuroimaging and intervention approaches to study whether between-person difference in neurogenesis is the common mechanism influencing memory and mental health. As such, our findings will contribute to a better understanding of the role of neurogenesis in the living human brain and its relationship to memory and depressive symptoms in adults without a psychiatric diagnosis.

The student is expected to fulfil the course requirements of the doctoral program, participate in regular group meetings, seminars, and present at national/international meetings. Most importantly the student is expected to plan and drive the research projects, participate in the data collection, analyze, and present results.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

We are looking for a highly motivated doctoral student who is efficient, thorough, and enjoys working in an international and dynamic multidisciplinary team.

Requirements

• Applicants should have second-cycle background in neuroscience, cognitive science, psychology, or some other relevant area

• Prior knowledge in neuroscience and cognitive psychology
• Experience in recruiting participants and data collection
• Computer programming ability (particularly in Matlab and R)
• Good communicator in English (both orally and in writing)

Merits

• Prior knowledge and skills in MR neuroimaging
• Good communicator in Swedish (both orally and in writing) which will be beneficial when communicating with participants

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

Aging Research Center (ARC) | Karolinska Institute

Cognitive Aging and Mental Health Group

Want to make a difference? Join us and contribute to better health for all

Deadline: 2024-02-26 at 23:59
Unit: Forskargrupp Hartman

Read the job description at the university homepage or apply.

Do you want to contribute to top quality medical research?

The research group of Professor Maria Eriksson at the department of Biosciences and Nutrition is looking for a highly motivated postdoctoral researcher to study somatic mutations in age-associated disease. The research aims at understanding the role of somatic mutations and their functional relevance in the development of age-associated diseases. We use both patient material and animal models combined with modern genomic technologies that allow for detailed analysis down to single-cell resolution to try to answer disease-relevant questions. https://ki.se/en/bionut/genetic-mechanisms-of-ageing-maria-eriksson

Your mission

Somatic cells accumulate thousands of mutations during development and aging. However, detailed analysis and insight into the extent of somatic variance in the vascular tissue is lacking. You will study the clonality of the vascular wall in human tissue samples and generate advanced mouse models based on lineage tracing to follow the fate of mutated cells. The aim is to define functional implications of somatic mutations in relation to aging and age-associated cardiovascular disease. The research work includes standard molecular biological techniques, mouse phenotyping and modern omics-approaches. You are expected to be part of the group and to develop in accordance with the common group goals and research interests.

Your profile

Applications are invited from highly motivated individuals with a PhD and a strong background in molecular biology or molecular genetics. Previous experience from work with human samples, mouse models and modern genomics technologies is required. Experience from work on the vascular system and lineage tracing, using confetti or similar strains, and rare event detection, is advantageous. Successful candidates are enthusiastic, responsible, able to perform their own experiments and analysis. They can provide suggestions and support in experimental design and experimentation to other members of the group. Fluency in written and spoken English is a requirement.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

The research group is part of a larger “Aging and Cancer” space that consists of 6 other research groups located next to each other within Neo, a modern research building, just across the street to the hospital. Such stimulating environment allows for several arrangements of joint events and promotes daily interactions, collaborations and sharing of expertise.

This position is a temporary employment (non scholarship) for 2 years with the possibility of extension of 1 + 1 year. 

Location: Flemingsberg

https://ki.se/en/bionut/genetic-mechanisms-of-ageing-maria-eriksson

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply at the latest 29 February 2024.

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2024-02-29 at 23:59
Unit: Forskargrupp Hartman

Read the job description at the university homepage or apply.

Do you want to contribute to improving human health?

Division

The research in Galina Selivanova’s lab is focused on the identification and studies of the mechanisms and the impact on the tumor suppression p53 on anticancer immune response. To reach this goal, we use small molecules as research tools and apply systems biology and high throughput assays, such as transcriptome profiling, ChIP-seq, and shRNA screens. We aim to bridge cancer biology with immunology studies by performing multidisciplinary research at MTC, a very advantageous environment including experts in cancer and cell biology and immunology.

Duties

We are seeking a highly motivated and dedicated researcher to carry out an exciting endeavor aiming to elucidate the mechanisms of interaction of the p53 tumor suppressor with immune system. You will take part in a highly collaborative and multidisciplinary research programme involving cancer and cell biology and immunology.

Entry requirements

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.

A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.

To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

In addition to the aforementioned requirements, the applicant must:

• Hold a PhD in an appropriate scientific field, with at least 4 years of relevant and productive work experience and qualifications.

Meritorius for the position:

• Experience with cell culture, flow cytometry, IHC, ELISA, basic molecular techniques (SDS-PAGE, Western blot, qPCR) and experience in animal models (mouse) are highly desired.
• Experience with high throughput assays is preferred.
• Applications will be particularly welcome from candidates who utilize creative experimental approaches at the interface between cancer biology and immunology.
• Experience with supervision and teaching skills are beneficial.
• Solid experience and excellent track record in the cancer field will be considered a distinct advantage.

Location: Solna

https://ki.se/en/about/choose-to-work-at-ki-ten-reasons-why

https://ki.se/en/mtc/galina–selivanova-group

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2024-02-28 at 23:59
Unit: Forskargrupp Hartman

Read the job description at the university homepage or apply.

Deadline: 2024-02-23 at 23:59
Unit: Forskargrupp Hartman

Read the job description at the university homepage or apply.

Do you want to contribute to top quality medical research?

Our research interest is to understand the cellular dynamics that drive the formation of different components of the intervertebral discs during embryonic development, and the plasticity of adipose tissue in response to environmental changes (https://ki.se/en/bionut/cellular-and-molecular-mechanisms-underlying-intervertebral-disk-formation-and-diversity-and). We will mainly use single cell/nucleus RNA sequencing methods combined with genetic lineage tracing to tackle these scientific questions. Our findings will innovate the current research frontier in the fields of developmental and metabolic biology and inspire the develop of novel treatment strategy against spine-related and metabolic disorders.

Your mission

The postdoc will study the transcriptomic profiles of genetically traced intervertebral disc cells and adipose tissue cells. The research work includes single cell/nucleus data analysis, confocal imaging, immunofluorescence and standard molecular biology techniques. The postdoc is expected to have the ability to independently drive research projects.

Your profile

We are looking for a highly motivated postdoctoral candidate with strong independent working ability. To address the above-mentioned questions, the candidate must have significant experience in bioinformatic analysis of single cell/nucleus RNA sequencing and spatial sequencing data, demonstrated in the form of published research paper in high-quality internationally peer-reviewed journals. Previous experience in mouse handling, tissue sectioning, immunostaining, confocal microscopy and image processing will be an asset. Fluency in oral and written English, independency in research and good team-working spirit are required.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Flemingsberg

https://ki.se/en/bionut/cellular-and-molecular-mechanisms-underlying-intervertebral-disk-formation-and-diversity-and

Choose to work at KI – Ten reasons why

https://ki.se/en/bionut/department-of-biosciences-and-nutrition

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply at the latest 23 February 2024. 

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2024-02-23 at 23:59
Unit: Forskargrupp Hartman

Read the job description at the university homepage or apply.

Do you want to contribute to top quality medical research?

The Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet conducts research and teaching within immunology, infection biology, cell biology and cancer. MTC have about 40 research groups and our key words are multidisciplinary, bridging, national and international collaborations.

The Pelechano laboratory is located at the Science for Life Laboratory (SciLifeLab, http://www.scilifelab.se/) in the Karolinska Institute campus. SciLifeLab is equiped with state-of-the-art instrumentation and core facilities, and is home to one of the largest sequencing cluster in Europe.

Our group combines experimental and computational work, and aims to develop and apply novel genome-wide techniques to address fundamental biological questions with medical implications. We are especially interested in how subtle variations in gene expression can lead to differential cellular phenotypes and are passionate about RNA biology (http://pelechanolab.com/). You will have the opportunity to work in a highly interdisciplinary and international environment and combine the development of state-of-the art genome-wide approaches with the molecular dissection of fundamental biological problems.

Are you interested in unravelling the eukaryotic post-transcriptional regulatory code? Would you like to combine the use of cutting-edge genome-wide technologies with synthetic biology and machine learning to study RNA life? Come and join us at SciLifeLab!

Your mission

The available postdoctoral position concerns developing and applying novel genomic approaches to study eukaryotic gene expression at an unprecedented scale combining experimental and computational approaches.

The candidate will work in the context of a recently awarded ERC synergy project (EPIC – Unravelling the eukaryotic post-transcriptional regulatory code) in collaboration with the labs of Prof. Kevin Verstrepen (Leuven) and Prof. Julien Gagneur (Munich). EPIC will combine the use of genomic, synthetic biology, machine learning and evolutionary approaches with the aim to understand the complete gene expression regulatory code of S. cerevisiae and other eukaryotes.

The recruited candidate will focus on mapping and prediction mRNA boundaries at an unprecedented scale. The candidate will also use the generated information to quantify and predict how mRNA variations lead to divergent mRNA fates. The candidate will integrate different experimental and computational approaches for the completion of the project, including genomics, yeast genetics, high-throughput biology approaches and bioinformatics. The candidate will perform original research in transcriptomics and computational biology, and acquire the required experimental and computational skills necessary for the completion of the project.

The candidate is expected to communicate the scientific results by writing up scientific papers and attending scientific meetings. The ideal candidate will participate in the general duties of the team and effectively communicate with scientists of very diverse backgrounds in a highly interdisciplinary and international environment.

Working language is English.

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

In addition to the aforementioned requirements:

• Applicants to this position should have a PhD in Molecular biology, Biotechnology, Genetics or similar field.
• The successful applicant should have experience interpreting biological data and experimentally testing their hypothesis with a strong interest in interdisciplinary technology development.
• Suitable candidates should have extensive experience with molecular biology methods such as RNA-Seq, ATAC-Seq, molecular cloning and RNA biology.
• Research experience with large-scale analyses and bioinformatics (NGS, batch and/or R/Python scripting languages) is also necessary.
• A strong interest in interdisciplinary technology development, and novel and creative thinking abilities are essential. 
• Good interpersonal skills and ability to work in teams is essential.

Meritorius for the position:

• Previous experience in yeast genetics, transcription/post-transcriptional mRNA regulation, high-throughput robotics and synthetic biology will be a merit.

In the appointment, special weight will be attached to scientific skill of relevance to the project and to previous research experience. 

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna

http://pelechanolab.com/

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

Welcome to apply at the latest 2024-02-25

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2024-02-25 at 23:59
Unit: Forskargrupp Hartman

Read the job description at the university homepage or apply.

Do you want to contribute to top quality medical research?

The Department of Medical Epidemiology and Biostatistics conducts research in epidemiology and biostatistics across a broad range of areas within biomedical science. The department is among the largest of its type in Europe and has especially strong research profiles in psychiatric, reproductive, pediatric, pharmaco, genetic, and geriatric epidemiology, eating disorders, precision medicine, and biostatistics.

Part of the success of our department is due to our collaborative spirit where one factor is that researchers at the Department share and co-finance common resources (e.g., IT and an applied biostatistics group). The department is situated at campus Solna. Further information can be found at http://ki.se/en/meb

The Department is the project owner of the SISU consortium, which aims to investigate the “Post-Pandemic Vulnerability and Resilience: A bioecological approach towards youth well-being in Nordic Schools and Communities (SISU)”. The SISU consortium led by the Principal Researcher Agnieszka Butwicka, is a collaborative project funded by Nordforsk involving four Nordic countries (Sweden, Norway, Finland, and Iceland). Its objective is to enhance our knowledge of vulnerabilities and resilience to inform future interventions for the improved well-being of young people. 

Your mission

We seek a motivated and innovative postdoc to join our leading team at Karolinska Institute. This individual should be passionately committed to furthering the knowledge to improve young people’s mental health.

Research at KI, as part of the SISU consortium, will specifically examine the impact of individual characteristics on the mental health, education, and well-being outcomes of young individuals, with a particular emphasis on vulnerable populations.

SISU builds on exceptional opportunities for Nordic countries with extensive longitudinal data sets, including school and municipality surveys, prospective cohort studies with genetic data, and population-based registries providing comprehensive information on all levels of bio-ecological influences. Methods will include a wide range of genetically informative and quasi-experimental study designs.

The duties will require the use of advanced statistics and high-performance computing resources. The successful applicant will closely collaborate with SISU consortium parents in Norway, Finland, and Iceland.

The open position is for a duration of two years, with the possibility of extension.

Your profile

The position requires a PhD degree with a focus on psychiatry, epidemiology, biostatistics, statistics, or a closely related field.

The applicant should also have the following: 

•  Knowledge and experience with classic and modern statistical methods in the genetics field (e.g., structural equation modelling, polygenic risk score).
• Knowledge and practical skills in epidemiological study designs and statistical analysis (e.g., linear and logistic regression, survival analysis, generalized estimating equation).
• Prior experience working with large data sets.
• Experience in managing and analyzing data using advanced programming languages and software (e.g., R, SAS).
• Exceptional organizational skills and project management.
• Excellent oral and written communication skills in English, along with experience with scientific writing. 

The work involves close collaboration with others and demands flexibility and excellent communication skills. A high degree of accuracy and independence is also important. We attach great importance to personal qualities in this recruitment.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna

International staff 

KI Postdoc Association

Choose to work at KI – Ten reasons why

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2024-02-28 at 23:59
Unit: Forskargrupp Hartman

Read the job description at the university homepage or apply.

Do you want to contribute to leading research on human reproduction and regenerative medicine?

If you do, the Department of Women’s and Children’s Health is the place that you are looking for! Our department consists of six divisions with approximately forty research groups, conducting leading education and research with a global impact on women’s and children’s health. Research on human reproduction and regenerative medicine are core interests of our department, which vision aligns with Karolinska Institutet’s mission of advancing medical knowledge through innovative basic research, in one of the world’s leading hubs for medical research.

Your mission

In this project, you will focus on the investigation of human primordial germ cell (hPGC) specification and early development, which occurs during early human embryonic development. To model and decipher the mechanisms behind hPGC early development, you will utilize human pluripotent stem cells and organoid cultures conjugated with single-cell and spatial transcriptomics. Your research will contribute to shed light on early germline development and pave the way for developing efficient protocols for in vitro gametogenesis. You will work under the supervision of assistant professor João Pedro Alves-Lopes, who is leading this project and line of research in the lab.

Your profile

We are seeking a highly motivated and enthusiastic postdoctoral fellow to join our research team. The ideal candidate should possess a critical mind and a passion for advancing scientific knowledge. The successful candidate will actively engage in scientific discussions, fostering a collaborative environment with other team members. Strong communication skills are essential, as the role involves not only contributing to cutting-edge research but also sharing insights and discoveries with colleagues. The ability to supervise and mentor master’s and Ph.D. students is a key aspect of this position, making it an excellent opportunity for individuals eager to contribute to both their academic growth and the development of emerging researchers. If you are a dedicated researcher with a commitment to excellence, innovation, and collaboration, we invite you to apply and be part of our scientific journey.

We are looking for a candidate with the following set of skills:

• Experience in maintaining and differentiating human pluripotent stem cells.
• Expertise in establishing and maintaining human organoid cultures and 3D cell cultures.
• Demonstrated skills in histological techniques, including cryosectioning.
• Proficient in operating confocal microscopy equipment and analysing imaging data.
• Experience in utilizing Fluorescence-Activated Cell Sorting (FACS) for cell sorting and analysis.
• Expertise in preparing libraries for single-cell RNA sequencing.
• Competence in molecular biology techniques, including cloning methodologies.

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna, Stockholm

Application

An employment application must contain the following documents in English or Swedish:

• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page) taking in consideration the following questions:
        o How does your current research align with the topic of the project described here?
        o Can you provide examples of how you have applied innovative approaches or        methodologies in your current research?
        o How are you collaborating with current team members in your current research?
• A motivation letter explaining (no more than one page)
         Why are you the ideal candidate for this position?
         Why are you interested in this position?
         What are your ambitions with this position?

Welcome to apply at the latest March 5, 2024

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2024-03-05 at 23:59
Unit: Forskargrupp Hartman

Read the job description at the university homepage or apply.

Do you want to contribute to improving human health?

Asthma is among the most common chronic diseases with an estimated 339 million cases worldwide, resulting in over 250,000 deaths each year. A major challenge is that “asthma” is an umbrella diagnosis for obstructive airway diseases with variable clinical presentations (phenotypes) and distinct mechanistic pathways (endotypes). There is a need to identify the fundamental biochemical dysregulations (metabotypes) associated with the etiology and pathophysiology of asthma in order to improve quality of life for individuals with asthma.

Division

The Unit of Integrative Metabolomics in the Institute of Environmental Medicine (IMM) consists of multiple researchers focused on the use of metabolomics to perform molecular phenotyping of individuals in response to disease or environmental stressors. These efforts are combined with integrative modeling to identify biochemical pathways associated with specific disease sub-phenotypes towards the goals of 1) understanding the etiology of disease processes & 2) identifying markers of the onset as well as resolution of system-based stress. The Unit is housed in the Biomedicum building at the Karolinska Institute in a new purpose-built mass spectrometry facility. The Unit includes multiple mass spectrometers and the associated sample processing equipment as well as dedicated wet and dry laboratory space.

Duties

We have an opening for an individual wishing to join a multidisciplinary team aimed to understand the biochemical dysregulations that drive the development of asthma. Towards that end, the successful applicant will take the lead in analyzing multiple projects that involve integrating metabolomics and lipidomics data with other omics (e.g., proteomics, transcriptomics) as well as clinical phenotyping data. For examples of previous efforts, please see: PMID: 34824054, PMID: 35314841, PMID: 34737220, PMID: 32667261, PMID: 29545283, PMID: 30335973. The primary challenge will be to identify the key molecular drivers of the different sub-types of asthma. Much of the work will involve the use of data from the U-BIOPRED project to investigate severe asthma (https://bit.ly/41gv8iY), as well as metabolomics data from multiple intervention trials to investigate the use of biologics to treat asthma. The overarching aim is to use the findings to develop diagnostic tests for identifying molecular sub-phenotypes of asthma.

Your profile

We are looking for highly motivated candidates with a Ph.D. in epidemiology, data science, or statistics – or who can demonstrate via publications the acquisition of the necessary experience. Individuals with the following skills are encouraged to apply: excellent quantitative and applied research skills in data analysis, demonstrated proficiency in statistical language (e.g., R, Matlab), good bioinformatics knowledge of metabolomics, and strong oral and written communication skills. The candidates’s time will be devoted to data analysis, manuscript preparation, and career development. Prior experience working biological datasets, or high-dimensional data and knowledge in biology and respiratory diseases is a significant merit. Excellent communication skills and an ability to interact socially and scientifically with other members of the laboratory and with international collaborators are essential.

Entry requirements

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Location: Unit of integrative metabolomics, Institute of environmental medicine, Solna

http://www.metabolomics.se/ https://ki.se/en/imm/unit-of-integrative-metabolomics

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2024-02-29 at 23:59
Unit: Forskargrupp Hartman

Read the job description at the university homepage or apply.