Tag-arkiv: Karolinska

Postdoctoral Researcher in oral and intestinal mucosal immunology

Do you want to contribute to top quality medical research?

The Department of Medicine, Solna, is one of the largest departments at Karolinska Institutet. The department consists of several units that are separated into different research groups. The core activities of the department are research, doctoral education and undergraduate education for medical and biomedical students. The research has three main profiles: allergy, cardiovascular medicine and inflammatory diseases.

Your mission

The nasopharynx and the oral mucosa are the gate of first encounter between environmental elements and the gastrointestinal tract. The complexity of different and well differentiated mucosal tissues, as well as the presence of distinct microenvironments, make the oral cavity a unique mucosal barrier that has been largely understudied. It is known that the oral cavity could be a mirror of systemic diseases, such as IBD and CRC, and that the disturbances in the oral immune homeostasis could be linked with systemic illness. However, the molecular and cellular mechanisms behind those interactions and its consequences in health or disease are still unresolved. The goal of this project is to elucidate how the disruption of the immune homeostasis at the oral or gut mucosal barriers could influence each other, and to propose the potential mechanisms behind those interactions. The successful candidate will first characterize and analyze the changes in the oral and gut immune cell network using different IBD or colorectal cancer mouse models in order to first stablish the potential interactions occurring during those conditions. The candidate will also generate strategies to reveal the potential cellular and molecular mechanisms governing those changes, and to understand the impact of those interactions on clinical outcomes of IBD and CRC patients and in novel therapies for the treatment of inflammatory bowel diseases, using mouse models and human samples. In summary, our proposal aims to understand the mechanisms of intestinal homeostasis and the consequences of its disruption at the oral cavity level, as well as the potential effects of homeostasis disruption at the oral mucosal barriers on the gut. This new knowledge will provide much-needed insights into aspects of oral and intestinal homeostasis that will contribute to an integrated understanding of the gastrointestinal tract as a whole and may lead to novel cellular therapies to treat IBD and CRC.

Your profile

Our lab has an opening for a highly creative and motivated postdoctoral scientist with an interest in mucosal immunology. We look for a candidate with proficiency and documented laboratory research experience particularly in oral microbiology/immunology, animal models of IBD and CRC, culture in vitro and multi-parameter flow cytometry in the context of mucosal immunology, and strong clinical skills and experience in inflammatory oral diseases. The candidate is expected to work with mouse models of intestinal inflammation and colorectal cancer, and must be able to handle and obtain oral human samples.

Experience in bioinformatics analysis would be an advantage. The position will require independent work at the laboratory as well as extensive collaboration with other experimental groups. Fluency in both oral and written English is necessary. Documented ability to analyze and present results orally and written is important.

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant’s main supervisor, director or equivalent.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location

The position is located within the Department of Medicine, Solna. The department consists of twelve divisions and each division consists of several research groups. The position is located within the research group lead by Associate Professor Eduardo Villablanca at the Immunology and Allergy division. In this project, our research group tries to understand the molecular and cellular mechanisms underlying the homeostatic or pathological interactions between the oral cavity and the gut, in the context of mucosal immunology. We aim to elucidate the influence of inflammatory bowel disease (IBD) and colorectal cancer (CRC) in oral immunosurveillance. The project has an emphasis in the identification of the molecular and cellular mechanisms involving the immune cell network and microbial interactions at the oral cavity and intestinal mucosal barrier.  Methodologically, in vitro and in vivo approaches using experimental models and patient material will be used. Our group works in an inspiring and interactive research environment at the Karolinska University, Solna and has ongoing collaborative projects with national and international colleagues.

For more information about our group, please visit:

https://ki.se/en/meds/eduardo-villablanca-group

https://villablancalab.com/

Twitter: @ejvillablanca

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work A complete list of publications A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all

Deadline: 2022-05-25 at 23:59

Read the job description at the university homepage or apply.

Post expires on onsdag maj 25th, 2022

Postdoctoral Researcher in the role of the intestine in cardiometabolic disease

Do you want to contribute to top quality medical research?

Your mission

Cardiometabolic disease is to a large part underlying the vast increase in non-communicable diseases observed in recent years; particularly relevant for the current project are the components obesity, insulin resistance, non-alcoholic fatty liver disease(NAFLD)/steatohepatitis (NASH) and atherosclerotic cardiovascular disease. The intestinal compartment is the first line of contact with food and serves as integrator and relay for signals derived from the interplay of microbiota, food, different epithelial cell types and immune cells. The current project aims to mechanistically explore how these interactions impact cardiometabolic disease and to delineate the signalling pathways involved. The intended experiments span from cell culture to in vivo models of disease (including work with germ-free models). Results from multiple layers of information derived from bulk RNA and single cell sequencing together with proteomics and metabolomics will be integrated to discover and map novel signaling pathways. These approaches are complemented with lipid biochemistry and in vivo characterization of metabolism using dynamic tests.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant’s main supervisor, director or equivalent.

To qualify, you should have a background in biomedical sciences with interest and experience regarding the work with cell culture as well as with preclinical animal models.  In addition, ample knowledge with respect to general laboratory techniques such as cloning and qPCR is a requirement. Good proficiency in English, both oral and written is required.

Experience with in vivo studies in disease models is particularly of advantage. Prior knowledge in bioinformatics (working with large data sets as e.g. generated by RNA sequencing), metabolism, intestinal (patho)physiology, microbiota, (primary) cell culture and molecular biology is also an advantage.

We are looking for a highly motivated, structured, enthusiastic and scientifically driven candidate interested in exploring how organs mechanistically communicate to regulate metabolism. The person should exhibit a high degree of independence but on the other hand also value a collaborative approach to science and enjoy working in a team. 

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.


Location:
Flemingsberg

Choose to work at KI – Ten reasons why

 

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work A complete list of publications A summary of current work (no more than one page)

Welcome to apply at the latest 31 May 2022.

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all

Deadline: 2022-05-31 at 23:59

Read the job description at the university homepage or apply.

Post expires on tirsdag maj 31st, 2022

Postdoctoral Researcher in radiology and experimental Surgery

Do you want to contribute to top quality medical research?

This position is a translative research position between medical imaging and liver surgery. The ideal candidate has experience of both. Our goal is to evaluate liver function and predict liver growth after hepatectomy.

Your mission

As a postdoctoral researcher in Radiology, you will:

  • perform animal experiments and imaging using MRI, Ultrasound and CT.
  • perform advanced image analyses.
  • plan and perform experimental and eventually also clinical studies in close cooperation with transplant surgeons, radiologists and radiographers.
  • take an active part in seminars and supervision of PhD students.

Your profile

To be a successful candidate, you have experience from evaluating liver function by MRI and you have passed the necessary animal courses to perform animal research in Sweden. You have experience in RIS and PACS and you have previously performed research using radiomics and/or artificial intelligence and deep learning. You have fluent knowledge in speaking and writing English. We are looking for a structured candidate with high social skills, who is able to work independently. We value personal qualities in the selection of candidates.

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant’s main supervisor, director or equivalent.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.


Location:
Flemingsberg

Division of Radiology
Choose to work at KI – Ten reasons why

 

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work A complete list of publications A summary of current work (no more than one page)

Welcome to apply at the latest May 27th, 2022.

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all

Deadline: 2022-05-27 at 23:59

Read the job description at the university homepage or apply.

Post expires on fredag maj 27th, 2022

Postdoctoral Researcher in Reproductive Endocrinology and Metabolism

Do you want to contribute to top quality medical research?

The research at our lab The Reproductive Endocrinology and Metabolism at the Department of Physiology and Pharmacology aims to yield new key information on the pathophysiology of polycystic ovary syndrome (PCOS). PCOS is linked to multiple severe health consequences, including reproductive, metabolic, and psychiatric disorders. The research is translational, and in collaboration with others, we combine register-based, cross-sectional, and longitudinal clinical studies with different mice models.

The group works in an inspiring and interactive research environment in Biomedicum at Campus Solna (see https://staff.ki.se/biomedicum-for-staff) and has on-going collaborative projects with national and international colleagues.

Your mission

The group combine in vivo and in vitro clinical and mice experiments with single cell multiomic sequencing of collected tissues to investigate epigenetic communication between germ cells, serum and somatic tissues aiming to identify molecular mechanisms underlying PCOS transmission to subsequent generations.

The postdoctoral applicant is expected to lead a project of single-cell sequencing of human tissue. The applicant will also be involved in mice projects investigating how transgenerational transmission of PCOS occurs by dissecting molecular mechanisms of epigenetic inheritance and causal links.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant’s main supervisor, director or equivalent.

We are looking for a passionate, highly motivated postdoctoral researcher with a PhD degree in reproductive endocrinology and metabolism, developmental biology, molecular biology or related area. We expect the candidate to have a strong scientific background with relevant expertise in single cell biology and developmental programming as well as processing and analyzing single-cell sequencing data. Experience from in vivo animal work including reproductive and metabolic phenotypic testing of mice, Crispr/Cas genome editing, and handling of human tissue samples is a strength.

Priority will be given to the applicant with proven ability to work independently. The person should be a positive team player as postdoc in part will be involved in supervision of master and PhD students in the group. Moreover, good communication skills and good proficiency in spoken and written English are necessary and Swedish is a strength.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. Karolinska Institutet is a state university, which entitles to several benefits such as extended holiday and generous occupational pension. Employees also have access to our modern gym for free and receive reimbursements for medical care.


Location: Biomedicum
Campus Solna

Read more about  Department of physiology and pharmacology 

Choose to work at KI – Ten reasons why

 

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

Welcome to apply!

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2022-06-01 at 23:59

Read the job description at the university homepage or apply.

Post expires on onsdag juni 1st, 2022

Postdoctoral researcher in Computational Biology (scholarship)

Do you want to contribute to top quality medical research?

Postdoctoral Researcher in mucosal immunology with focus in single-cell RNA-seq and spatial transcriptomics analysis and data visualization.

A postdoctoral position to study the transcriptomic landscape of intestinal tissue regeneration, with clear implications for intestinal diseases such as inflammatory bowel diseases (IBD) and colorectal cancer (CRC). The position is available in the laboratory of Dr. Eduardo Villablanca, who is a renowned leader in mucosal immunology (twitter @ejvillablanca). The candidate will be part of a research program that integrate experimental models, patient material and cutting-edge technologies (spatial and single cell transcriptomics) to understand how intestinal homeostasis is maintained and how breakdown in these processes might lead to IBD or CRC.

Division
Immunology and Allergy Division

Research group

The Immunology and Allergy Unit at the Department of Medicine, Solna performs research on different aspect of allergy and autoimmune diseases. Our research group (PI: Eduardo Villablanca) will investigates the molecular and cellular mechanisms underlying the establishment of intestinal homeostasis and how breakdown of these mechanisms might lead to inflammatory bowel diseases (IBD). Our group works in an inspiring and interactive research environment at the Karolinska University, Solna and has ongoing collaborative projects with national and international colleagues.

To tackle these questions, Eduardo’s team are using Single Cell RNA-Sequencing and spatial transcriptomics to generate a comprehensive transcriptomic landscape of the intestinal tissue during the reestablishment of intestinal homeostasis upon damage. We are closely collaborating with the clinics to translate our findings from experimental models.

Duties
We are seeking a Computational Biologist at post-doctoral level for a 24-48 months project. The main duties include bioinformatics analysis with particular focus in RNA-seq, single cell RNA-seq and spatial transcriptomics analysis. An interest in data visualization and big data analysis is a plus. The applicant is expected to have a strong interest in mucosal immunology. The applicant will work in close collaboration with other PhD students, postdocs and researchers. The applicant is expected to actively participate in other lab projects and present results to general and specialized audiences. An interest in the application of machine learning approaches is also desirable.

The duties also include: 

  •  Data QC, data management and archival storage
  • Analysis of large datasets, preparation of codes, development of new methods/tools for advanced analysis of datasets
  • Support the ongoing research in the group, help write papers, grants and scientific meeting presentations
  • Shape, develop and maintain the current computing resources of the group 

Entry requirements

The successful candidate has a solid background in bioinformatics, statistics and computational biology, good expertise in statistical and bioinformatics software, and an ability to work in a multidisciplinary research environment. The individual should be highly motivated and be able to work independently, while being able to communicate effectively with other members of the team.

Preferably, the candidate should hold a PhD degree (or complete one within the next 2 months) or have a track record of performing independent research over the past 4 years. A proven publication record in well-regarded journals is also advantageous. Outstanding programming skills in at least R, Matlab, Python, Perl or other mathematical software/programming languages is required.

Requirements: Qualified candidates should have:

  • A Ph.D. or M.D./Ph.D. in immunology or computational biology.
  • Outstanding creative thinking, problem solving, motivation, persistence as well as personal initiative and communication skills
  • Independent work at the laboratory as well as extensive collaboration with clinicians and other experimental groups.
  • Excellent molecular and cell biology as well as microbiology skills and strong background in mucosal immunology
  • Strong publication record in peer-reviewed journals
  • Fluency in both oral and written English is necessary

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent. A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four-year period following the receipt of a doctoral degree or equivalent.

To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Location

The position is located within the Department of Medicine, Solna. The department consists of twelve divisions and each division consists of several research groups. The position is located within the research group lead by Associate Professor Eduardo Villablanca at the Immunology and Allergy division. Our research group investigates the molecular and cellular mechanisms underlying the establishment of intestinal homeostasis and how breakdown of these mechanisms might lead to inflammatory bowel diseases (IBD). To tackle these questions, Eduardo’s team are using single cell RNA-sequencing and spatial transcriptomics to generate a comprehensive transcriptomic landscape of the intestinal tissue during the reestablishment of intestinal homeostasis upon damage. We are closely collaborating with the clinics to translate our findings from experimental models. Dr. Villablanca serves as co-director of the single cell RNAseq core at the Center of Molecular Medicine (CMM) and leads the bioinformatics group within the mucosal immunology lab.

For more information please visit:

https://ki.se/en/meds/eduardo-villablanca-group

https://villablancalab.com/

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2022-06-08 at 23:59

Read the job description at the university homepage or apply.

Post expires on onsdag juni 8th, 2022

Postdoctoral Researcher in Computational Cognitive Neuroscience

Do you want to contribute to top quality medical research?

In our research group, you will find a unique opportunity to work closely with top researchers in the borderland between psychology and neuroscience to jointly try to understand human cognition on a neural level. We offer an engaging and international research environment where you get an opportunity to contribute to high-quality research at an international top level.

Your mission

The project is focused on increased understanding of our working memory, an integral part of flexible cognition. In particular, the underlying mechanisms that lend humans their ability to generalize will be investigated in this interdisciplinary project. The postdoc will conduct multiple studies using network simulations (typically abstract, non-spiking networks like RNNs), to explore this is artificial systems. Part of the studies will be to compare the outcome to human and non-human neural data.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant’s main supervisor, director or equivalent.

To be eligible for the position, you must have completed your doctoral degree in in computational neuroscience/mathematics/computer science or equivalent. 

Knowledge and experience in network simulations, in particular with abstract, recurrent networks, is highly meritorious. As is training networks using for instance reinforcement learning. The applicant will be expected to quickly and independently be able to engage in these areas.

Due to the interdisciplinary nature of the position, emphasis will be put on the candidate’s ability to work and function in a team. Even if focus will be on network simulations experience with analyzing neural data is considered a plus. Prior experience working in teams is very valuable. The position will also entail a lot of independent work, so candidates can ideally demonstrate a history of independent work

Strong background in mathematics (linear algebra and similar) and fluency in English is required.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.


Location:
Solna

Department of Clinical Neuroscience 
Choose to work at KI – Ten reasons why

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

Welcome to apply at the latest June 15th 2022

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all!

Deadline: 2022-06-15 at 23:59

Read the job description at the university homepage or apply.

Post expires on onsdag juni 15th, 2022

Postdoctoral Researcher in Cognitive Neuroscience

Do you want to contribute to top quality medical research?

In our research group, you will find a unique opportunity to work closely with top researchers in the borderland between psychology and neuroscience to jointly try to understand human cognition on a neural level. We offer an engaging and international research environment where you get an opportunity to contribute to high-quality research at an international top level.

Your mission

The project is focused on increased understanding of our working memory, an integral part of flexible cognition. To this end, human cognitive and neuroimaging studies will be combined with analysis of data recorded intracranially in animal models (spikes, LFPs). In particular, the underlying mechanisms that lend humans their ability to generalize will be investigated in this interdisciplinary project. The postdoc will conduct multiple studies, both using EEG and MEG in human subjects as well as comparing EEG/MEG data to LFP data in animals.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant’s main supervisor, director or equivalent.

To be eligible for the position, you must have completed your doctoral degree in neuroscience or equivalent. 

Due to the interdisciplinary nature of the position, emphasis will be put on the candidate’s ability to work and function in a team. Prior experience working in teams is very valuable. The position will also entail a lot of independent work, so candidates can ideally demonstrate a history of independent work.

Experience in neuroimaging (EEG / MEG / LFPs / spiking) and analysis of such data (Matlab, MNE) is meritorious. As is designing and implementing cognitive experiments in animals and humans. The applicant will be expected to quickly and independently be able to engage in these areas.

Fluency in English is required. Excellent writing skills and fluency in Swedish are considered a plus. Experience working in an international environment will also be meriting.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.


Location:
Solna

Department of Clinical Neuroscience 
Choose to work at KI – Ten reasons why

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

Welcome to apply at the latest June 15th 2022

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all!

Deadline: 2022-06-15 at 23:59

Read the job description at the university homepage or apply.

Post expires on onsdag juni 15th, 2022

Doctoral (PhD) student position in Behavioral Informatics

Do you want to contribute to better health for all?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

The Behavioral Informatics team at Health Informatics Centre (The Department of Learning, Informatics, Management and Ethics) strives to find ways in which behavioral data can be used to optimize health interventions. We are currently focusing on interventions targeting work-related stress and improving workers’ well-being.

The doctoral student project and the duties of the doctoral student

In this project we are developing a data-driven monitoring system to efficiently track work-related stress reactions over time. The system also includes a self-awareness intervention based on evidence-based strategies to improve workers’ recovery. The doctoral student will work with research design, participant recruitment, and data collection. The tasks include coordinating the planned studies and being directly involved in data analysis, interpretation, and presentation of results, writing scientific articles and collaboration with the all the partners involved in the project.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

  1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
  2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
  3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

 

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

We are looking for an applicant with a degree within psychology, cognitive science or a related field. Applicants need to have documented knowledge in quantitative methods and analysis, as well as experience of working with statistical analyses in R. Experience of working with survey data and experience of scientific work in general is an advantage. Applicants need to have good collaboration skills, be attentive to details, relationship-building, and have the ability to work independently. In addition to this, we are looking for an applicant who is focused on quality and good at solving and responding to problems, and who has a strong drive of their own and an interest in health informatics. Personal suitability is crucial for this position.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

Read more about LIME.

Read more about the Behavioral Informatics Team.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2022-06-05 at 23:59

Read the job description at the university homepage or apply.

Post expires on søndag juni 5th, 2022

Postdoctoral studies in regeneration

Do you want to contribute to top quality medical research?

The Department of Cell and Molecular Biology (CMB) is a department with a strong focus on basic science. CMB conducts research and education in cell biology, molecular biology, developmental biology, stem cell biology, cancer and infection biology. CMB is located in Biomedicum, a new interdisciplinary research center designed to concentrate much of the experimental research conducted at Karolinska Institutet Campus Solna under one roof to promote collaboration. Biomedicum houses approximately 1,200 researchers and other personnel and allows expensive equipment to be shared and utilized more effectively.

Division and Duties

The Simon research group is studying regeneration processes in aquatic salamanders. Natural examples of regeneration, such as salamanders, may unravel novel strategies for cell replacement of damaged or lost tissues. We study regeneration mechanisms in an aquatic salamander, the newt, which has the widest repertoire of regenerative abilities among tetrapods. During the past decade, our laboratory has developed several methods, which has made these outstanding questions experimentally tangible. We place our findings on newt regeneration into an evolutionary context and test our results in a variety of mammalian in vivo and in vitro assays. The main target tissue of our investigations in the context of limb regeneration is skeletal muscle. Skeletal muscle can contribute to limb regeneration in two ways, either by activation of quiescent stem cells or by dedifferentiation of differentiated muscle fibers. By various cell tracking strategies, we try to compare these two processes to each other in terms of their relative contribution to the limb. We also characterize molecular processes involved in the generation of limb progenitors from skeletal muscle.

The successful applicant will focus on limb regeneration using state of the art cell and molecular biological tools and will be involved in developing new methodologies. It will be important to collaborate with other members of our team with overlapping projects.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant’s main supervisor, director or equivalent.

To qualify, the person must hold a PhD degree and have experience in limb regeneration or limb development in vertebrates, preferentially amphibians. Previous work with several model organisms is a merit. The person should have proved skillfulness by authoring scientific papers in peer reviewed journals.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.


Location:
Stockholm

Application

An employment application must contain the following documents in English or Swedish:

A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work. A complete list of publications. A summary of current work (no more than one page).

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2022-05-23 at 23:59

Read the job description at the university homepage or apply.

Post expires on mandag maj 23rd, 2022

Postdoctoral researcher in psychology with a focus on inequalities in mental health

Do you want to contribute to improving human health?

We are currently looking for a postdoctoral researcher who will be working on several research projects in a research group lead by Richard Bränström with a focus on inequalities in health and minority stress. The position entails participation in, planning, and conducting research studies that aim to identify risk factors and mechanisms of mental health in minority groups based on sexual orientation and gender identity. The position provides an excellent opportunity for transition to career independence and an engaging and international research environment where you will be able to contribute to internationally leading research.

Your mission

The post-doctoral associate will be based at the Division of Psychology, Department of Clinical Neuroscience, Karolinska Institutet. The postdoctoral researcher will mainly work with statistical analysis, manuscript writing, and grant applications. The appointment is for one-year that is potentially renewable contingent on funding and performance. The successful candidate will be a part of a productive and dynamic research environment and work closely with the study team to:

  • Obtain data across longitudinal time points and prepare data for analyses.
  • Develop analysis plans to test study hypotheses and conduct statistical analyses.
  • Prepare manuscripts for publication (The post-doctoral associate will have the opportunity to be the first author on several papers and a co-author on others).
  • Assist in project coordination tasks, including managing databases and overseeing participant retention efforts.
  • Outline an independent research development plan and attain experiences in education and supervision.

Your profile

Applicants should have a PhD in psychology, social epidemiology, sociology, or an allied discipline. The successful candidate must have experience in register and survey-based epidemiological research as well as data management and analysis using, e.g., SAS, STATA, SPSS, Mplus, or R. Excellent English skills is a requirement and Swedish skills are meriting. The work involves close collaboration with others and demands flexibility and excellent communication skills.

Qualified to be employed as a postdoctor is one who has obtained a doctorate or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant’s main supervisor, director or equivalent.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location: Solna

Department of Clinical Neuroscience 
The research group 
Choose to work at KI – Ten reasons why

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

Welcome to apply at the latest May 24th 2022

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all!

Deadline: 2022-05-24 at 23:59

Read the job description at the university homepage or apply.

Post expires on tirsdag maj 24th, 2022

Postdoctoral position (scholarship) in bioinformatics at Karolinska Institutet

 

Do you want to contribute to top quality medical research?

 

Karolinska Institutet is one of the world´s leading medical universities. Its mission is to contribute to the improvement of human health through research and education. Karolinska Institutet accounts for over 40 per cent of the medical academic research conducted in Sweden and offers the country´s broadest range of education in medicine and health sciences. Since 1901 the Nobel Assembly at Karolinska Institutet has selected the Nobel laureates in Physiology or Medicine.

Division

We are seeking a highly motivated postdoctoral researcher in bioinformatics to join a a research team dedicated to understand the function of 3D epigenome folding and its deregulation in human diseases from entirely novel perspectives. The candidate is expected to drive a postdoctoral project and participate in collaborative efforts to uncover hitherto unknown therapeutic targets in complex diseases, such as cancer. The work will be carried out at the department of Oncology and Pathology in the lab of Drs Anita Göndör. We have innovated state-of-the-art techniques enabling the analysis of 3D chromatin structures and chromatin fibre networks in single cells and small cell populations to provide unique opportunities for novel discoveries.

For further information about our work, please consult a selection of reports from our labs:

Nature genetics 51: 1723-1731 (2019); Science 359:1212-1213 (2018); Mol Cell 59:984-97 (2015); Nature Review Genetics 17:284-99 (2016); Nature, 461, 212-7 (2009)  Nature genetics, 2019, 51, 1723–1731, Nucleic Acids Research, 2020, 48, 10867–10876; Nat Commun Jan 11;13(1):204 (2012); Nature protocol, in press

Duties

The successful applicant will employ state-of-the-art bioinformatic techniques adapted to the analyses of single cells alongside more conventional ChIP-seq, RNA-seq and chromatin network analyses.

Entry requirements

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Other requirements

In addition, it is advantageous if the successful candidate has:

  •  Experience in the analysis of NGS data, in particular: RNA-seq, single cell RNA-seq, ChIP-seq, 3C-based chromatin interactome datasets
  •  Experience in network analysis
  •  Excellent knowledge in biostatistics 
  •  Extensive experience in using R/BioConductor, Unix/Linux environment (prior scripting language experience e.g. Python/Perl is a plus)
  •  Experience in data visualization
  •  Experience in meta-analysis
  •  Experience in SNP calling from NGS data is a plus
  •  Proficiency in written and spoken English
  •  Good understanding of biological concepts and/or willingness to learn
  •  Experience in working with wet lab scientists

A high level of organizational and communication skills, as well as an ability to independently perform experiments and implement interpretation of data is mandatory.

Location: Solna, BioClinicum

https://ki.se/en/onkpat/anita-gondors-group

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system June 7th at the latest.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2022-06-07 at 23:59

Read the job description at the university homepage or apply.

Post expires on tirsdag juni 7th, 2022

Postdoctoral scholarship dedicated to the experimental analyses of molecular features driving the evolution of breast cancer

Do you want to contribute to top quality medical research?

 

Karolinska Institutet is one of the world´s leading medical universities. Its mission is to contribute to the improvement of human health through research and education. Karolinska Institutet accounts for over 40 per cent of the medical academic research conducted in Sweden and offers the country´s broadest range of education in medicine and health sciences. Since 1901 the Nobel Assembly at Karolinska Institutet has selected the Nobel laureates in Physiology or Medicine. 


Division

We are seeking an outstanding candidate for a post-doctoral fellowship dedicated to explore the synergisms between the epigenome and the 3-dimensional nuclear architecture to effectuate oncogene expression from new perspectives. The successful applicant is expected to drive a postdoctoral project in the labs of Anita Göndör at the department of Oncology and Pathology, as well as to participate in collaborative efforts with both national and international collaborative labs with a focus on breast cancer. Our lab is equipped with a Mi-seq machine and a 5-color confocal microscope, and is located within the Theme Cancer section of BioClinicum at Karolinska Institutet.

For further information about our work, please consult a selection of reports from our labs:

Nature genetics 51: 1723-1731 (2019); Science 359:1212-1213 (2018); Mol Cell 59:984-97 (2015); Nature Review Genetics 17:284-99 (2016); Nature, 461, 212-7 (2009)  Nature genetics, 2019, 51, 1723–1731, Nucleic Acids Research, 2020, 48, 10867–10876; Nat Commun Jan 11;13(1):204 (2012); Nature protocol, in press

Duties

The successful applicant will employ state-of-the-art epigenomic techniques adapted to the analyses of single cells and single cell RNA-seq, to identify key features underlying the phenomenon of oncogene gating and its circadian regulation. Hands-on experience in advanced experimental techniques is essential.

Entry requirements

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Other requirements

A PhD in relevant research areas (molecular and cellular biology) is mandatory. A strong scientific track record, supported by published papers particularly on the subject of chromatin/nuclear architecture research in well-recognized peer-reviewed journals and previous experience in single cell techniques (DNA FISH, scRNA-seq etc) is advantageous. A high level of organizational and communicative skills, as well as an ability to independently perform experiments and implement interpretation of data is mandatory.

Location: Solna, BioClinicum

https://ki.se/en/onkpat/anita-gondors-group

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system June 7th at the latest.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2022-06-07 at 23:59

Read the job description at the university homepage or apply.

Post expires on tirsdag juni 7th, 2022

Postdoctoral Researcher in positive imagery project

Do you want to contribute to improving human health?

In our research group you will find a unique opportunity to work closely together with top researchers at the intersection of psychology and neuroscience. A current focus of Professor Emily Holmes’ research group is mental imagery and the development of innovative interventions to bolster mental health. We offer an engaging and international research environment in which you will have the opportunity to contribute to high-quality research at the highest international level in collaboration with Professor Michelle Moulds (The University of New South Wales, UNSW Sydney), Australia. The position is a full-time (100%) temporary position for 8 months.

Your mission

We are looking for a full-time postdoc to work in this clinical and experimental environment. You will work on a project investigating novel ways to use positive imagery (e.g., via brief online interventions) to improve mental health, both in individuals in the general community as well as those in vulnerable groups. You will also work (as needed) on projects being conducted by Professor Holmes which evaluate an intervention targeting memories of trauma.

Furthermore, you will work on administrative tasks associated with the research projects and support the research group leader and Professor Moulds on issues related to administration and feasibility. For example, you will participate in research documentation procedures with KI-ELN, strategies for using methods of open data and work on ethical and grant applications. You will also be involved in collaborations with other professionals involved in the projects in question.

Irregular working hours may be considered based on the needs of the data collection. You may need to travel within your service, both within and between Stockholm and Uppsala. You will attend weekly joint research group meetings.

Your profile

Qualified to be employed as a postdoctor is one who has obtained a doctorate Cognitive Neuroscience / Psychology, or has equivalent scientific competence. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant’s main supervisor, director or equivalent.

We are seeking an applicant with experience in:

  • memory research and conducting online experiments (Prolific, Gorilla)
  • projects management skills, showcasing the ability to work at speed/efficiently, and be flexible
  • open-science practices
  • presenting research results at international conferences, and preparing and submitting ethics, manuscripts for publication in scientific journals

The applicant must have high proficiency in English, in both speaking and writing, as a large part of the research group’s work and communication with external partners is in English. The applicant must show high degree of independence as well as experience of working collaboratively in an international environment.

The applicant should have excellent communication and problem-solving skills, along with good writing and spoken proficiency in a Nordic language. Knowledge of Swedish is a merit, but not a requirement. Good time management skills, experience in the collection and analysis of psychophysiological data and working with neuroimaging methods (EEG, fMRI), as well as expertise in scripting/programming are meritorious.

What do we offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.


Location:
Solna

Read more about the Department of Clinical Neuroscience
Read more about the research group 
Choose to work at KI – Ten reasons why

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

Welcome to apply at the latest May 17th 2022. 

The application is to be submitted through the Varbi recruitment system.

 

Want to make a difference? Join us and contribute to better health for all!

Deadline: 2022-05-17 at 23:59

Read the job description at the university homepage or apply.

Post expires on tirsdag maj 17th, 2022

Postdoctoral Researcher in chronic pain research

Do you want to investigate mechanisms leading to persistent pain?

We invite applications for a joint post doc position in Prof Camilla Svensson’s team that explores cellular and molecular mechanisms underlaying chronic pain states. The position will be placed in the Department of Physiology and Pharmacology at the Karolinska Institutet, which has a collegial, international and dynamic research environment. The Svensson lab is part the Center for Molecular Medicine (CMM) located on the premises of the Karolinska Hospital. We offer an exciting, open, and collaborative research work environment and project, where you can make a difference.

Your mission

The Postdoctoral Fellow that joins the team will be investigating pain mechanisms in rheumatic conditions. The project is focused on rheumatoid arthritis-associated autoantibodies and mechanisms by which they induce and sustain pain. The work will be performed in vitro as using primary cultures of neurons, satellite glial cells and osteoclasts as well as in vivo by undertaking behavioral pharmacological studies using animal models. You will be working closely together preclinical and clinical researchers and biostatisticians with a mission to increase our ability to study pain from a translational perspective.

Your profile

Qualified to be employed as a postdoctor is one who have a PhD in immunology, neuroscience, biomedical science, or another relevant field or has equivalent scientific competence. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) date of employment. This must be substantiated by the applicant’s main supervisor, director or equivalent.

You are a creative, hardworking and enthusiastic team player. You have a strong background neuroscience, immunology or neuroinflammation. Documented practical experience with primary cell cultures, immunocytochemistry, mRNA analysis and animal behavioral assessment are considered strong merits.

You can work independently but also have the interpersonal and communication skills to succeed at working in a multidisciplinary team. You have a deep sense of responsibility, take initiatives and have capacity and flexibility to work with researchers and students with different expertise.

You have a very good written and spoken English and is a good communicator, both when it comes to presentations and preparation of publications. You have good recommendations from previous supervisors/teachers.

What do we offer?

We offer a postdoctoral position for one year, with the possibility of extending the position. You will work in a creative, inspiring and vibrant research environment. You will be part of a research team that is dedicated to undertaking translational research with the ultimate goal to uncover cellular and molecular reasons behind pain chronicity and contribute to the improvement of life quality for individuals suffering from fibromyalgia.
The appointment will be at the Karolinska Institutet. For more information please visit: http://ki.se/en/fyfa/molecular-pain-research

You will receive post-doctoral training in the laboratory of Prof Svensson, who will provide mentorship and opportunities for personal and professional development and a platform for building a future career in research.

Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct cutting edge medical research and hold the largest range of medical education in Sweden.

Location: Solna

 

Application

An employment application must contain the following documents in English or Swedish:

  • A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)
  • A letter of motivation

In assessing candidates we will place emphasis o personal trajectory, education, personal and technical skills, CV, merits and previous experience as well as on personal qualities.

Welcome to apply!

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2022-05-20 at 23:59

Read the job description at the university homepage or apply.

Post expires on fredag maj 20th, 2022

Postdoctoral studies in Immunology (scholarship)

Do you want to contribute to top quality medical research?

An exciting opportunity to be part of the Karolinska Institutet biomedical research at the Department of Medicine Solna. The position is open at a dynamic and well-funded research group that applies multi-disciplinary and innovative approaches to reveal the underlying molecular mechanisms of disease pathogenesis (Nature 2021, Nature 2014, Cell 2015, etc. see lab page).  Besides providing access to cutting-edge technology and infrastructure, our lab offers a creative, collaborative and supportive environment full of expertise, passion and curiosity.

Division

The research group of Dr. Magdalena Paolino, included in the Department of Medicine, Solna, at the Bioclinicum building of the Karolinska University Hospital. With our research, we aim to go all the way from animal genetics to therapy, and we strive to have important implications for human health and disease treatment. The Bioclinicum provides an open and international research environment, top-notch in-house infrastructure, and access to daily seminars and lectures by world-leading scientist. Karolinska Institutet is one of the world’s leading medical universities and hold the largest range of medical education in Sweden.

Duties

We have vast experience in experimentally unraveling how diverse genes regulate the functions and responses of immune cells (Nature 2021, Nature 2018, Nature 2014, J. Immunol 2011). We are now looking for up to two highly motivated postdoctoral candidates to explore the function and mechanism of previously uncharacterized genes in the regulation of selected immune cells. The projects aim to from all the way from genes, to cells, and finally, to the whole organism. Thus, the postdoc is expected to apply molecular and cellular biology techniques to characterize in depth the gene function at the cellular levels in immune cells and then use animal models to reveal the impact of these findings in the pathophysiology of diseases in vivo, specifically in metabolic diseases and cancer. For these tasks, he/she will combine mouse genetics and in vivo disease models with a wide range of state-of-the-art approaches, including cell biology, molecular and immunological experimental methods, such as flow cytometry analysis, viral-based gene editing via CRISPR/Cas9 and shRNA, histology and microscopy, next generation sequencing and cell culture models. The applicant is expected to work in a diligent way to take the lead and responsibility in generating properly controlled scientific data of high quality.

Entry requirements

The applicant is eligible to apply if he or she has obtained a PhD in Cancer biology, Immunology, Biochemistry, Molecular Biology, or related fields. Proven competence in functional in vivo studies using animal models in the fields of immunology is required. Candidates must demonstrate experience working with immune cells in vivo and in vitro, including flow cytometry. Expertise in ubiquitination research and/or working with neutrophils or T regulatory cells are advantageous for this position.  

The ideal candidate should be creative and goal-oriented, with a scientific drive and proven scientific track record, and thrive in an interdisciplinary and international environment. The candidates should be able to work independently and take a strong lead in managing the project. Good interpersonal and communication skills in English, spoken and written, are required. Personal suitability for the group will also be a strong selection criterion.

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.
A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.
To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

Location

The position is located within the Department of Medicine, Solna. The department consists of twelve divisions and each division consists of several research groups. The position is located within the research group  of Dr. Magdalena Paolino, funded by the Karolinska Institutet, the Swedish Research Council, the Ragnar Söderberg Foundation and Cancerfonden.

https://ki.se/en/meds/team-magdalena-paolino

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)
  • A letter of motivation for the position
  • Contact details of two references (to be included in the CV)

The application is to be submitted on the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2022-05-22 at 23:59

Read the job description at the university homepage or apply.

Post expires on søndag maj 22nd, 2022

Doctoral student position in Targeted cell death and immune modulation in glioblastoma

Do you want to contribute to top quality medical research?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

The research group of Sten Linnarsson is located at Biomedicum in the Molecular Neurobiology unit, at the Department for Medical Biochemistry and Biophysics, MBB. The Mol Neuro unit is a highly creative and collaborative environment that shares expertise, equipment, and lab space between groups in the unit. The unit has regular seminars where students and post docs present their work and get feed-back from the unit members.

Linnarsson lab currently consists of 16 members and have a weekly group meeting where members present their work and discuss scientific publications. All students have weekly scheduled meetings with their supervisor and collaborators. All members of the group are encouraged to participate in workshops and conferences and interact with scientists within KI as well as internationally

The doctoral student project and the duties of the doctoral student

The project is a part of a larger effort in the Linnarsson group to create a highly specific therapeutic agent for glioblastoma (GBM). The project advertised here will contribute towards this goal in two ways. Firstly, the project entails finding an optimal mechanism for inducing targeted immunogenic glioblastoma cell death. To this end, the student will perform screenings of well-known cell death inducing proteins and engineered derivatives thereof. This work will be conducted in murine animal models by grafting transfected murine cell lines as well as patient derived GBM organoids. The second aim is to characterize and modulate the immune response evoked by the targeted cell death. Therein, the same GBM models will be leveraged for immunomodulatory factor screening.

To achieve these aims, the student will have to independently perform transfection experiments on cell lines and organoids to help establish glioblastoma animal models with inducible expression of candidate proteins. The readout for protein screening experiments will be mostly microscopy-based. The corresponding duties of the student will entail processing the harvested tissues, performing microscopy and image analysis. More specifically, the student will perform both conventional histology staining and high-throughput single molecule RNA fluorescence in situ hybridization (smFISH) experiments. The student will operate custom microscopes and fluidics systems adapted for smFISH experiments, as well as use and further develop highly automated computational image processing and analysis pipelines.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

  1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
  2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
  3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

 

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

Candidates must have extensive practical experience in fluorescence microscopy. Any experience in technical troubleshooting and maintenance of wide-field microscopes is also advantageous given that the student will mainly work with customized microscopy setups. Similarly, experience in operating and maintaining automated fluidics systems is highly sought after.

Expertise in smFISH methods is necessary, especially pertaining to method development and protocol optimization, as a variety of smFISH modalities might need to be implemented throughout the project. The prospective student is expected to have a general overview of the spatial transcriptomics field and to be able to readily implement optimal chemistry choices (e.g., glass surface coating, tissue clearing, or signal amplification strategies) most suited for different experimental needs. Similarly, candidates should be able to design custom oligonucleotide probes for smFISH experiments. Prior experience with more conventional tissue stainings, such as lectin conjugates, is also desirable.

Experience with mammalian cell or tissue culturing is advantageous but not strictly required. However, given the precious nature of tissue samples to be used in the project, applicants must have experience in handling biological tissues for microscopy purposes (e.g., freezing, cryosectioning).

Applicants must have a firm grasp of Python programming language and prior experience implementing it for image processing and analysis (filtering, segmentation, etc.). Furthermore, general knowledge and basic skills of single-cell transcriptomics analysis methods are required for handling and interpreting smFISH data (e.g., spot-cell assignment, principal component analysis).

Regarding general competences, the student will often be expected to perform laboratory work with minimal supervision but in high collaboration with other group members. Therefore, extensive laboratory work experience as well as excellent communication skills are essential. Given that the project will largely revolve around protein screening in vivo with therapeutic implications, applicants must be prepared to work with utmost diligence and organization regarding both experimental work and data presentation. Lastly, the student will be expected to show a high degree of engagement and original thinking when planning the experiments and reviewing results together with the supervisor and other group members

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2022-05-22 at 23:59

Read the job description at the university homepage or apply.

Post expires on søndag maj 22nd, 2022

Doctoral (PhD) student position in Perinatal Epidemiology

Do you want to contribute to top quality medical research?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

The Clinical Epidemiology Division is one of the larger divisions at the Department of Medicine, Solna with around 100 employees and 60 affiliated researchers or PhD students. The majority of the researchers are clinically active. There are currently eight statisticians employed at the Clinical Epidemiology Division, who are part of an active network with the purpose of developing and implementing methods in biostatistics.

The research group in reproductive epidemiology is a young and rapidly growing group at the Clinical Epidemiology Division and includes 25 professionals, including researchers, postdocs and PhD-students. Our research focus on risk factors and interventions during pregnancy, childbirth and the neonatal period and outcomes for both mother and child. We have a strong collaboration with clinical departments, including paediatrics, obstetrics and gynaecology and other national and international research groups as well as other organizations like the World Health Organisation (WHO). The group has extensive experience in research in perinatal outcomes using advanced methods in biostatistics and clinical epidemiology. Please see Olof Stephansson’s homepage at Karolinska Institutet for more information on our research (http://ki.se/en/people/oloste).

The doctoral student project and the duties of the doctoral student

Neonatal survival has risen substantially in the last two decades in high income countries, especially in infants born very preterm (at <32 weeks’ gestation) and very low birth weight (at <1500gm). 1 These surviving preterm infants face a high risk of major neurodevelopmental disorders later in childhood and adolescence, and these risks increase with decreasing gestational age at birth. 2 There are very few large contemporary population-based birth cohorts examining long-term prognosis for preterm and term infants and those with complex neonatal conditions. This project aims to fill these knowledge gaps about longer-term prognosis for infants with prenatal factors and severe neonatal morbidity that put them at risk for early mortality and severe morbidity.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

  1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
  2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
  3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

The applicant must have experience in performing statistical analysis, as well as an understanding of Swedish register and electronic medical record data, register linkages and performing register-based research. A high level of knowledge of statistical software, preferably in SAS, R or Stata, is preferred.  The applicant must have some medical knowledge, or research background in pediatrics or neonatology will be considered as merit.  It is required that the applicant is able to work independently as well as a part of a research group. We are looking for a candidate who is curious about pediatric epidemiology and enjoys learning new things. The applicant should be detail-oriented and well-organized, with the ability to manage several projects simultaneously. The applicant must communicate well in written and in spoken English.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

–[Video about Karolinska Institutet, how we all work towards “a better health for all”] –

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

The employment will be at the Department of Medicine, Solna. The Department consists of twelve divisions and each division consists of several research groups. The position is located within the  research group of Olof Stepansson, Reproductive Epidemiology at the Clinical Epidemiology Division.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2022-05-26 at 23:59

Read the job description at the university homepage or apply.

Post expires on torsdag maj 26th, 2022

Postdoctoral studies in Alzheimer’s Disease (scholarship)

Do you want to contribute to top quality medical research?

Research group
The postdoctoral position is for lab (experimental) based research and the postdoctoral fellow will be working in the research group of Professor Agneta Nordberg ‘Translational Molecular Imaging Lab’ which consists of multi-disciplinary team of experienced researchers and clinicians working at the forefront of translational dementia research. The research group has a translational approach using both in vitro and in vivo molecular brain imaging techniques, and our aim is to explore the complex pathophysiological features of neurodegenerative diseases, with a strong focus on Alzheimer’s disease (AD) but also other neurodegenerative disorders, to develop novel diagnostic markers and drug targets for early intervention in disease pathophysiology.

Duties

We are inviting applications for the position of postdoctoral researcher in translational research with a strong focus on understanding the role of different pathological hallmarks (Amyloid, Tau, astrocytes, microglia, synaptic loss and other biomarkers) in the pathogenesis of AD and other dementia disorders. The position will give you the opportunity to work on translational/clinically relevant projects aligned with the broad goals of the research group not limited to AD and involves other neurodegenerative disorders such FTD, Parkinson’s disease etc.

The duties will involve day to day lab work, compilation of data and manuscripts writing for publication, participating, and presenting progress updates in internal group meetings, division’s PhD/Postdoc seminars and journal club and at national/international conferences when required.

Entry requirements

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent.

A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent. To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

We are looking for someone who has research and lab experience in the field of Alzheimer’s disease and other dementia disorders as well as hand on expertise in protein biochemistry, immunohistochemistry, cell culture and other biochemical techniques. The candidate should be self-motivated, with a strong interest in research, and able to work both independently as well as being a good team player with excellent communication skills in English (written and verbal). The candidate should be reliable, detail-oriented and collaborative, and with an ability to work without requiring extensive training or the need for close supervision. Experience of work in international research laboratories and good publications record are appreciated. The postdoctoral position is for 1-year initially with the high possibility of extension considering all the criteria are fulfilled.

Location: Flemingsberg

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English or Swedish:

  • A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  • A complete list of publications
  • A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2022-06-01 at 23:59

Read the job description at the university homepage or apply.

Post expires on onsdag juni 1st, 2022

Postdoctoral Researcher in Materials Science

Ming Wai Lau Centre for Reparative Medicine (MWLC) aims to contribute to the improvement of human health by conducting cutting-edge research in reparative medicine and related subjects, by creating a new platform for synergies between academia and innovation in Sweden and Hong Kong as well as China, and fostering future leaders in both academia and industry.

Description of Research Group and Position
The current research of Assistant Professor Sijie Chen aims at developing novel fluorescence-based tools and technology for biological research.

One Postdoctoral Researcher position in Materials Science is available.

Responsibility and Requirements
We are looking for a highly motivated, creative researcher, who enjoys an interdisciplinary, open and collaborative environment, with the following qualifications, experience and skills:

  • Completion of a PhD degree with strong background in Materials Science, Chemistry, Bioengineering or related disciplines.
  • Sufficient background knowledge and experience in design, synthesis, and characterization of polymers, nanomaterials or biomaterials, and fluorescent materials.
  • Experience in microfluidics, cell biology and bioimaging is an advantage.
  • A strong publication record in peer reviewed journals.
  • Excellent written and oral communication skills in English. 

Entry requirements
At Karolinska Institutet the Postdoctoral Researcher position is regarded as an early career step after a doctoral degree. Qualified to be employed as a Postdoctoral Researcher is one who has obtained a doctorate or has equivalent scientific competence.

To be qualified for this position, a doctorate or an equivalent degree in Materials Science, Chemistry, Bioengineering or related disciplines is required.

The employment
This is a one-year fixed-term position, with the possibility of renewal.

The assignment is located at MWLC, Hong Kong, and the employment will follow local labour laws in Hong Kong.

A competitive remuneration package including 10% on top of basic salary (fully-taxable) intended as pension will be offered in addition to MPF employer’s contribution and medical benefits.

Application process
An employment application must contain the following documents in English:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A doctoral certificate or equivalent
• A complete list of publications
• A summary of current work (no more than one page)
• Applicants should arrange to have at least two letters of reference

The application is to be submitted through the Varbi recruitment system.

Interviews will start when applications are received until the position is filled.

Karolinska Institutet is one of the world’s leading medical universities. Our vision is to advance knowledge about life and strive towards better health for all. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.

Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.

Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.

For temp agencies and recruiters, and to salespersons: We politely, yet firmly, decline direct contact with temp agencies and recruiters, as well as those selling additional job announcements.

Want to make a difference? Join us and contribute to better health for all!

Deadline: 2022-06-05 at 23:59

Read the job description at the university homepage or apply.

Post expires on søndag juni 5th, 2022

Doctoral (PhD) student in position in clinical immunology

Do you want to contribute to top quality medical research?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

Within our group we perform immunological research, and our focus is unconventional T cells, especially γδ T cells, as these immune cells have not so far been efficiently exploited. We are investigating γδ T cell reconstitution and functionality after hematopoietic stem cell transplantation (HSCT) and in patients with solid tumors. This could help pave the way for more advanced and targeted approaches in cancer immunotherapy and in infectious diseases. We offer an engaging and international research environment where you may contribute to high quality research on an internationally competitive level.

The doctoral student project and the duties of the doctoral student

We are looking for a highly motivated person with an interest in human immunology.

The successful candidate will:

  • be responsible for the isolation and culturing of T cells from peripheral blood, as well as performing immunological tests of these cells.
  • collect and isolate lymphocytes from patients with ovarian cancer.
  • characterize the cells using a wide range of immunological and biochemical techniques such as flow cytometry, various immunoassays and immunoquencing.
  • carry out most of the experimental work and will plan the experiments, analyze data and interpret and summarize results.
  • participate in all research-related activities such as group meetings, departmental seminars, national / international seminars, as well as standard laboratory routines of the group.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

  1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
  2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
  3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

 

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

We are looking for a motivated candidate with high social skills, who enjoys working in a collaborative environment. The candidate must be able to work independently and have knowledge of how to ask and interpret scientific questions and to critically review the results. Since the applicant will work in a very international environment, good communication skills in English, in speech and writing, are crucial.

Previous experience with cell culture work of primary immune cells, microscopy (confocal and fluorescence) and animal work are seen as meritorious. We would like the candidate to have experience in bioinformation and biostatistics.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.


Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

Michael Uhlin research group

 

Want to make a difference? Join us and contribute to better health for all

Deadline: 2022-05-24 at 23:59

Read the job description at the university homepage or apply.

Post expires on tirsdag maj 24th, 2022