Research assistant – mitochondrial genetics

Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Division of Molecular Metabolism

Karolinska Institutet, Department of Medical Biochemistry and Biophysics, Division of Molecular Metabolism
The Division of Molecular Metabolism ( at the Department for Medical Biochemistry and Biophysics ( is located at the newly built and modern Biomedicum research laboratory ( at Solna campus of Karolinska Institutet. Our research aims at understanding the regulation of mitochondrial function and the role of mitochondrial dysfunction in disease and ageing. The current research encompasses biochemical and genetic studies of patients with inherited diseases as well as basic scientific approaches to understand the regulation of mtDNA expression, mitochondrial biogenesis and mitochondrial metabolism. Both patient material (tissues and cells), genetically modified fruit flies (Drosophila melanogaster) and mice (Mus musculus) are used in these studies. The overall aim of the Division of Molecular Metabolism is to combine these different areas of research to get insights into disease pathophysiology and to develop novel treatments. The Division of Molecular Metabolism offers an outstanding research environment and a close interaction between basic science and clinical science and diagnostics at the Centre for Inherited Metabolic Diseases (CMMS) at Karolinska University Hospital, Stockholm, Sweden. The newly founded Max Planck Institute for Biology of Ageing – Karolinska Institutet Laboratory (MPI-KI laboratory) is also integrated into our laboratory. Excellent access to the most advanced resources in molecular and cell biology is available at the department and at the national core facilities at the Science for Life laboratory (https://

We are currently looking for a Research Assistant to form an essential part of our research team in mitochondrial genetics, led by Professor Nils-Göran Larsson. The responsibilities of the Research Assistant will be varied and include:

*Performing diverse molecular biology techniques e.g. extracting RNA, DNA or protein from cells and/or mouse tissues, PCR, qRT-PCR and western blotting.
*Genotyping mice.
*Ordering, receiving, and distributing chemicals and laboratory supplies, and handling of invoices.
*Assisting with inventory and organization of chemicals and lab materials.
*Preparing and aliquoting reagents, for instance preparation of fly food

We welcome applications from candidates with academic qualifications at least corresponding to BSc in Biomedical Laboratory Science, Biomedicine, Molecular Biology, or other related fields. The successful candidate is a responsible, service-minded person with good communication and organizational skills who enjoys working with people and take pride in delivering work of good quality. The work requires:
*Excellent communication skills and a service focus.
*Good organizational skills and attention to detail.
*Previous experience of laboratory work and molecular biology techniques is an advantage.

The working language is English. Good knowledge of the Swedish language is an advantage. The applicant must be able to integrate well into the international and multidisciplinary environment. Personal suitability is therefore of great importance.

Application process
An employment application must contain the following documents in English or Swedish:

1. Curriculum vitae (max 2 pages)

2. Personal motivation letter (max 1 page)

3. Contact information of at least two references

The application is to be submitted in Varbi recruitment system.

At Karolinska Institutet a 6-month trial period is required for all permanent appointments.

Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.

Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.

Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.

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Type of employmentTemporary position longer than 6 months
Contract typeFull time
First day of employmentupon agreement
CountyStockholms län
Reference number2-1751/2019
ContactContact Camilla Koolmeister – head of divison , +46 8 524 830 39
Union representativeBiborka Bereczky Veress, SACO, 46 70-173 85 75Henry Wölling, SEKO, 08-524 840 80Anne Edgren, OFR/S, P, O, 08-524 87570
Last application date07.Apr.2019 11:59 PM CET

Post expires on Monday April 8th, 2019