Postdoctoral Researcher in project focused on dopamine neurons, stem cells and regenerative medicine

Karolinska Institutet,

The Department of Cell and Molecular Biology (CMB) is a department with a strong focus on basic science. CMB conducts research and education in cell biology, molecular biology, developmental biology, stem cell biology, cancer and infection biology.

A postdoctoral position is available in the lab of Thomas Perlmann at the Department of Cell and Molecular Biology at Karolinska Institutet, one of the world´s leading biomedical research institutes. The lab is located at Biomedicum, a newly opened research building with excellent infrastructure and world leading research.Our primary focus is on the development of dopamine neurons and the ventral midbrain region where dopamine neurons are generated. We are unraveling the signaling and transcriptional regulation that govern the specification, differentiation and maintenance of these cells. The studies have resulted in the identification of several transcription factors with key roles in these processes. Moreover, we are also interested in regenerative medicine in relation to Parkinson´s disease and other brain disorders. We are using mouse genetics and methods such as single cell RNA sequencing in our studies. In collaborative projects we also focus on regenerative strategies such as stem cell therapy, and on the maintenance of dopamine neurons in the human brain.

We now have an opening for a postdoc in projects devoted to questions concerning the potential for neurogenesis of dopamine neurons in the adult brain, development and subtype specification of dopamine neurons, and mechanisms underlying aging and dopamine neuron maintenance.

Entry requirements
The applicant should be a highly motivated scientist who can collaborate, communicate and function well in a team. We are looking for an individual with a PhD in neuroscience, stem cells or developmental biology, and with skills preferably in more than one of the following areas: human embryonic stem cells, mouse genetics, bioinformatics and histological methods.

Application process
An employment application must contain the following documents in English or Swedish:

  1. A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
  2. A complete list of publications
  3. A summary of current work (no more than one page)

The application is to be submitted through the Varbi recruitment system. Karolinska Institutet is one of the world’s leading medical universities. Its vision is to significantly contribute to the improvement of human health. Karolinska Institutet accounts for the single largest share of all academic medical research conducted in Sweden and offers the country’s broadest range of education in medicine and health sciences. The Nobel Assembly at Karolinska Institutet selects the Nobel laureates in Physiology or Medicine.
Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.
Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.

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Read the job description at the university homepage

Type of employmentTemporary position longer than 6 months
Contract typeFull time
Number of positions1
Working hours100%
CountyStockholms län
Reference number2-7413/2018
ContactThomas Perlmann,,
Union representativeMagnus Anå, OFR, 08-524 864 37, magnus.ana@ki.seBiborka Bereczky Veress, SACO, 46 70-173 85 75 , biborka.bveress@ki.seElisabeth Valenzuela, SEKO, 08-524 863 53,
Last application date28.Feb.2019 11:59 PM CET

Post expires on Thursday February 28th, 2019