The Center for Microbial Secondary Metabolites, CeMiSt, is a Center of Excellence funded by the Danish National Research Foundation. The Center started 1st of January 2018 and will run for six years with an option for a four-year extension. The Center is based at the Technical University of Denmark and hosted by Department of Biotechnology and Biomedicine (DTU Bioengineering). Three DTU departments and 10 senior faculty participate in the Center and >15 PhD students and postdocs will be hired. The purpose of CeMiSt is to unravel the biological role of microbial secondary metabolites in natural microbiological communities. The Center is led by Professor Lone Gram.
DTU Bioengineering covers microbial ecology and physiology, industrial biotechnology and biomedicine and health. The department consists of approx. 30 faculty and more than 80 PhD students and postdocs.
The research area of the position is within fungal ecology, genetics and natural product chemistry with a focus on the analysis of the interaction between secondary metabolite producing microorganisms.
We are looking for an ambitious mycologist with a broad experience in fungal ecophysiology, genetics and secondary metabolite production.
You will get a unique possibility to work on fungal (and bacterial) ecosystems focusing on how secondary metabolites of terrestrial fungi affect microbial diversity and functionality in both natural and engineered systems.
You will be collaborating with scientists working on microbial ecology, bioinformatics, molecular microbiology and analytical chemistry on several topics:
- Determining fungal diversity in selected eco-niches and mock communities
- Developing strategies for constructing mock-microbial communities
- Characterizing secondary metabolite biosynthetic pathways
- Developing strategies for assessing the impact of individual secondary metabolites in shaping microbial communities
- Constructing deletion (or overexpressing) mutant libraries in Penicillium and other fungi with emphasis on biosynthetic gene clusters
The position allows you to collaborate with several research groups with expertise in microbial ecology, molecular microbiology, gene sequence analyses and analytical and structural chemistry.
Candidates should have a PhD degree in molecular mycology covering several of the following qualifications:
- Experience with experimental (wet-lab) work with filamentous fungi
- Experience with isolation and characterization of filamentous fungi
- Experience with chemical and/or genetic analyses of secondary metabolites
- Experience with genetic manipulation of filamentous fungi
- Fluent in English
You must be ambitious, well organized, structured and enjoy interacting with many different people including PhD students and postdocs. Also, a good sense of humor will be appreciated.
In the assessment of the candidates consideration will be given to:
- Research experience and documentation
- International experience
- Internal and external collaboration
- Communication skills
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed with the relevant union.
The postdoc position is available for 3 years.
More information can be found here: career paths at DTU here.
Please submit your online application no later than 31 January 2019.
To apply, please open the link “Apply online”, fill out the online application form. The following must be attached in English:
- Application (cover letter)
- Diploma (MSc/PhD)
- List of publications
Applications and enclosures received after the deadline will not be considered.
All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply.
The Center for Microbial Secondary Metabolites aims to establish what effect microbial secondary metabolites have on other microorganisms in their natural environment. We have traditionally perceived them as ‘competition substances’,but in natural environments they are rarely produced in quantities of antibiotic effect. The Center’s hypothesis is that secondary metabolites constitute a network of signal molecules that directly affect gene expression, behavior, and metabolism of the microorganisms and thus play a decisive role in the composition and function of microbiological societies. We will explore this in an interdisciplinary collaboration with the use of analytical-chemical, bioinformatic, molecular biological, and classic microbiological methods.
The Department of Biotechnology and Biomedicine (DTU Bioengineering) conducts research, educates the future bio-engineers, provides scientific advice and innovate within the areas of microbiology, biochemistry, biotechnology andbiomedicine. The research at DTU Bioengineering is at the highest international level and focuses on the societal and scientific challenges within the field. Research is conducted within three main areas: Microbial ecology and physiology, Industrial biotechnology and cell factories, and Biomedicine and health. The department has extensive collaboration with national and international research units and industries. DTU Bioengineering has approx. 180employees, of which 2/3 is scientific staff. The department is located at DTU Lyngby Campus
DTU is a technical university providing internationally leading research, education, innovation and scientific advice. Our staff of 6,000 advance science and technology to create innovative solutions that meet the demands of society, and our 11,200 students are being educated to address the technological challenges of the future. DTU is an independent academic university collaborating globally with business, industry, government and public agencies.
Deadline: 31 January 2019
Unit: DTU Bioengineering
Read the job description and apply online
Post expires on Thursday January 31st, 2019