Postdoctor in Spatial and Single Cell Bioinformatics

KTH Royal Institute of Technology

KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as architecture, industrial management, urban planning, history and philosophy.

A post-doctoral position is available at the Department of Gene Technology at Science for Life Laboratory (SciLifeLab) in Stockholm. SciLifeLab is a Swedish national resource center for life science research. We are looking for an enthusiastic and talented postdoctoral researcher to join the lab of Professor Joakim Lundeberg, affiliated with the School of CBH at KTH Royal Institute of Technology in Stockholm.

Job description

The work will consist of bioinformatics/computational method development its applications for gene expression analysis in single cells and in tissue sections combined with imaging data. A particular focus is on Spatial Transcriptomics technology (Ståhl et al Science 2016; Salmen et al Nat Prot 2018), developed in a collaboration between KTH and KI, that provides spatially resolved transcriptomes in tissue sections (i.e. RNA seq and imaging data). The proposed project aims to be included as part of the Human Developmental Cell Atlas project hosted at SciLifeLab.

In this project we are using a multiple of tools and competences such as single cell RNA, Spatial Transcriptomics, In situ Sequencing and CODEX protein analysis in order to describe and catalog the genes involved in human development of brain, heart and lungs. A key component of the position is to provide new biological knowledge into the studied systems requiring some understanding of the investigated tissues. This project will be in collaboration with internal and external experimental and computational researchers.

Qualifications

The successful candidate will have a Ph.D. (or equivalent) in computational science, mathematics, physics, bioinformatics, molecular biology, biotechnology or related field with a strong background, and knowledge of molecular biology. Thorough experience with Unix (or a variant thereof), R, scripting software (e.g., Python) or other programming languages such as C++ is required. Experience with handling large sequencing data sets, and from bioinformatics method development, is highly desired.

The ability to work both independently and collaboratively is highly valued. Excellent command of written and spoken English is a requirement. The postdoctoral researcher will be employed by KTH Royal Institute of Technology and the workplace is at SciLifeLab Stockholm.


Trade union representatives

You will find contact information to trade union representatives at KTH:s webbpage.

Application

The application should include the following documents (preferably combined into one single pdf):

(i) a letter stating your research experience and interests
(ii) a curriculum vitae including list of publications
(iii) name and contact information for yourself and two or three references

Log in to KTH’s recruitment system in order to apply to this position. You are responsible to ensure that your application is complete according to the ad.

Your complete application must be received at KTH no later than the last day of application, midnight CET/CEST (Central European Time/Central European Summer Time).

Other information

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Disclaimer: In case of discrepancy between the Swedish original and the English translation of the job announcement, the Swedish version takes precedence.

Type of employmentTemporary position longer than 6 months
Contract typeFull time
First day of employmentAccording to agreement
SalaryMothly salary
Number of positions2
Working hours100%
CitySolna
CountyStockholms län
CountrySweden
Reference numberC-2018-2007
Contact Joakim Lundeberg, Professor, joakim.lundeberg@scilifelab.se
Last application date20.Jan.2019 11:59 PM CET

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Scheduled maintenance

Saturday the 12th of January there will be an extended system maintenance, starting at 08:00 CET (estimated done at 13:00 CET). The system will not be available during this maintenance.

Post expires on Sunday January 20th, 2019