Post doc in molecular biophysics focused on Bayesian Modeling

Lunds universitet, Naturvetenskapliga fakulteten, kemiska institutionen

Lund University was founded in 1666 and is repeatedly ranked among the world’s top 100 universities. The University has 40 000 students and 7 400 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition. The Faculty of Science conducts research and education within Biology, Astronomy, Physics, Geosciences, Chemistry, Mathematics and Environmental Sciences. The Faculty is organized into nine departments, gathered in the northern campus area. The Faculty has approximately 1500 students, 330 PhD students and 700 employees.

Job description

We are looking for a highly motivated candidate to run a project where Bayesian statistical methods are developed to analyze experimental data interrogating the three-dimensional structure of proteins.  

A central goal in this project is to solve fundamental challenges involving of how proteins self-assemble to form larger structures using time-resolved experimental data, primarily from small angle scattering (SAS). The candidate will develop Bayesian approaches to infer kinetic models of self-assembly processes from the experimental data. The project will also involve the development of other statistical inference methods coupled to the analysis of SAS data, and additional methods to investigate the structure of mixtures of proteins in solution.  

We would consider candidates with two different backgrounds for this position. Either a computational statistician with expertise in Bayesian modelling. Alternatively, an SAS expert with experience in computational method development. 

Candidates with computational statistics background are not required to have an expertise in protein science or scattering methods, but should have an interest in applying probabilistic modeling to problems in chemistry and physics. 

Qualifications 

Qualifications computational statistics background: 

  • The applicant should have a PhD in statistics, computer science, machine learning, bioinformatics, biophysics or other relevant fields.
  • The applicant should have experience in computational probabilistic modeling. Experience of analysis of data analysis with Bayesian statistical methods using Markov Chain Monte Carlo sampling methods is required.
  • The applicant should have substantial experience of developing programs for advanced statistical computation platforms.
  • The candidate must also be fluent in English (written and spoken). 

Candidates with SAS background are not required to have an expertise in Bayesian statistics, but should have acquired an understanding of the theoretical basis for probabilistic modeling methods and have an interest in applying such methods in SAS.  

Qualifications SAS background:

  • The applicant should have a PhD in chemistry, physics, biophysics or other relevant fields.
  • The applicant should have substantial experience in computational modeling of SAS data.
  • The applicant should be experienced in scientific software development.
  • The candidate must also be fluent in English (written and spoken). 

The following experiences are considered meriting:

  • Background in one or more of the following languages: C++, C, Matlab, Python, R
  • Experience with probabilistic modeling frameworks such as Stan, PyMC3 or Edward.
  • Background in Bayesian graphical networks
  • Background in protein modeling

Lund University welcomes applicants with diverse backgrounds and experiences. We regard gender equality and diversity as a strength and an asset. We kindly decline all sales and marketing contacts.

Type of
employ
ment
Temporary position longer than 6 months
Contract typeFull time
First day of employmentAs soon as possible for two years
SalaryMonthly salary
Number
of positions
1
Working hours100
CityLund
CountySkåne län
CountrySweden
Reference numberPA2018/4127
Contact Ingemar André, Senior Lecturer, +46 46-2224470Magdalena Brossing, Hr officer, +46 46-2229562
Union representative OFR/ST:Fackförbundet ST:s kansli, 046-222 93 62SACO:Saco-s-rådet vid Lunds universitet, 046-222 93 64SEKO: Seko Civil, 046-222 93 66
Last application date20.Jan.2019 11:59 PM CET

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Post expires on Sunday January 20th, 2019