The Hevesy Laboratory at DTU Risø Campus is offering an exciting fellowship opportunity for a posdoctoral scientist with an ambition to become later an academic independent researcher or an industrial scientist in the burgeoning field of nuclear medicine. This research project is supported by the Independent Research Fund Denmark and focuses on development of a technology for cyclotron-based, continuous production of radiopharmaceutical grade 68GaCl3.
The radioisotope 68Ga is driving medical imaging and is experiencing high adoption rate in clinics. 68Ga-PSMA is emerging as the gold standard for prostate cancer diagnostics, and a plethora of other generic and proprietary tracers are actively in development and clinical use. Currently, all medical 68Ga is supplied by gallium generators, which can suffer from limited availability, high prices, and inherently low yield of 68GaCl3. This research effort will develop Gallec, the first automated system able to continuously produce 68GaCl3 solution for preparation of PET radiopharmaceuticals. When commercialized, Gallec will enable hospitals to switch from purchasing gallium generators to 68Ga production using an in-house cyclotron and existing radiosynthesis equipment.
Responsibilities and tasks
The successful candidate will have a significant freedom and play a major role within the framework of this project. Specifically, the candidate will:
- Develop experimental methods, separation techniques, and analytical approaches needed to isolate and purify 68Ga, and other relevant radionuclidesPerform sample and data analysis and interpret resultsParticipate in running and optimization of the cyclotron production of 68Ga using a solution targetParticipate in automation of the separation stepsDocument research, present results within the radiochemistry community and at conferences , write manuscripts and patent applications
Recent (< 4 years) PhD in nuclear chemistry, nuclear physics, nuclear engineering, radiochemistry, or related field.
- Experience with radionuclide separation methods, such as liquid-liquid extraction and ion exchange chromatographyExperience with radionuclidic analyses, such as gamma-ray spectroscopy, radio-TLC, radio-HPLCExcellent verbal and written communication skillsExperience with running cyclotron solution targets, LabView programming, and membrane-based radionuclide separation is highly desirable
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.
The Hevesy Laboratory is a radiochemical and radiopharmaceutical division within the Center for Nuclear Technologies (DTU Nutech), with about 25 employees. The laboratory has a 16.5 MeV cyclotron equipped with a beam line for in-house production of PET radionuclides (18F, 64Cu, 89Zr, 68Ga, 45Ti). Apart from the clean rooms used for routine production of radiopharamceuticals our facilities include state-of-the-art chemistry and biology research equipment. At present, the research group at the Hevesy laboratory consists of a young and dynamic multidisciplinary team with a focus on the development of new radiopharmaceuticals for diagnostics and therapy. Our research is interdisciplinary and features active national and international collaboration. We strive for academic excellence in an environment characterized by collegial respect and academic freedom. English is a preferred language for all scientific communications.
Salary and terms of employment
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed with the relevant union. The position is full-time, initially with a fixed term of 21 month, which might be extended further subject to availability of funding. The employment starts on September 1st, 2018 or as soon as possible. The place of work is the Hevesy Laboratory, DTU Risø Campus in Roskilde.
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Further information may be obtained from Senior Researcher Fedor Zhuravlev, +45 4677 5337, email@example.com
The application deadline is 30 June 2018 (local time). Apply online at www.career.dtu.dk.
Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link “Apply online”, fill out the online application form, and attach all your materials in English in one PDF file. The file must include:
- Cover LetterCVDiploma (MSc/PhD)List of publications
Applications and enclosures received after the deadline will not be considered.
All interested candidates irrespective of age, gender, race, religion or ethnic background are encouraged to apply.
DTU is a technical university providing internationally leading research, education, innovation and scientific advice. Our staff of 6,000 advance science and technology to create innovative solutions that meet the demands of society, and our 11,200 students are being educated to address the technological challenges of the future. DTU is an independent academic university collaborating globally with business, industry, government and public agencies.
Deadline: 30 June 2018
Unit: DTU Nutech
Read the job description and apply online
Post expires on Saturday June 30th, 2018