Category Archives: Health/Life sciences

Doctoral student in bioinformatics (PA2024/339)

Faculty of Medicine, Department of Experimental Medical Science

Lund University was founded in 1666 and is repeatedly ranked among the world’s top universities. The University has around 45 000 students and more than 8 000 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition.

Lund University welcomes applicants with diverse backgrounds and experiences. We regard gender equality and diversity as a strength and an asset.

Background

We are looking for a full-time bioinformatics PhD student to be involved in the Novo Nordisk funded project: ‘Development of phage biocontrol to overcome the antiphage defense system arsenal of phytopathogenic Ralstonia solanacearum bacterium’. This is a project led by Ville Friman in the University of Helsinki, with Vasili Hauryliuk and Gemma C. Atkinson in the University of Lund as co-investigators. This position will be based in the Atkinson lab.

Due to a lack of efficient control methods, plant-pathogenic bacteria threaten safe and stable food production. This project will develop a novel biocontrol method against the plant-pathogenic bacterium Ralstonia solanacearum by employing its natural viral enemies, phages. While phages are highly pathogen-specific and safe to the environment, they can become inefficient due to the rapid development of phage resistance. This project will overcome this by identifying antiphage defence systems in R. solanacearum, and then isolating phages that can counteract these defences by escaping their recognition or by deploying their own counter-defence systems.

Description of the research group

In the Atkinson lab we are interested in making discoveries about protein function and structure, with a focus on bacterial immune system components that protect against bacteriophages and other mobile genetic elements. We work mainly with bioinformatic methods, developing our own tools and taking advantage of the wealth of available genome and predicted proteome sequences. The Atkinson lab is based in the Faculty of Medicine of Lund University, in the Department of Experimental Medical Sciences (EMV) and is affiliated with the Lund University Virus Centre (LUVC). We strive for a supportive, respectful and stimulating working environment that promotes personal and professional development for all members.

Further information:

The Atkinson lab

https://villefrimanscience.weebly.com/

https://portal.research.lu.se/en/persons/vasili-hauryliuk

https://www.medicine.lu.se/faculty-medicine-lund-university/departments/department-experimental-medical-science

We offer

Lund University is a public authority which means that employees get particular benefits, generous annual leave and an advantageous occupational pension scheme.

Read more on the University website about being a Lund University employee Work at Lund university 

Responsibilities

In this computational PhD project you will be using and developing tools for analysing bacterial genomes and predicting phage defence systems. You will work together with the other project team members in understanding and overcoming barriers to phage-based biocontrol in pathogenic bacteria. You will also be involved in the Atkinson lab’s joint effort to develop and maintain a publicly accessible bioinformatics toolbox (https://server.atkinson-lab.com/).

This collaborative project will provide valuable networking and training opportunities including research visits to Helsinki University, and you will have the opportunity to attend and present your work at international meetings.

Qualifications

The positions requires:

  • Coding skills in Python
  • Proficiency in spoken and written English
  • Experience in using and/or developing computational methods for biological discovery
  • Background understanding of, and interest in bacteriophage biology
  • Ability to conceive, execute, and complete research projects independently
  • Creativity and good group-working skills 

Desired qualifications:

  •  Experience in creating pipelines for use with high performance computing clusters
  •  Competence in large dataset handling 

How to apply

Include the following documents in your application:

  1. A cover letter (one page) with the following sections:

Motivation (half a page). Explain your interest in the project, motivation for applying, and what you hope to learn

Eligibility and experience (half a page). Explain how you fulfil the eligibility and expertise requirements, describe your previous relevant experience and outline how you will contribute to the research group.

2. A CV (maximum 2 pages) with contact details of two referees

3. Bachelors and Masters certificates

For more information contact Gemma C. Atkinson gemma.atkinson@med.lu.se

Eligibility
Students with basic eligibility for third-cycle studies are those who- have completed a second-cycle degree- have completed courses of at least 240 credits, of which at least 60 credits are from second-cycle courses, or- have acquired largely equivalent knowledge in some other way, in Sweden or abroad.

The employment of doctoral students is regulated in the Swedish Code of Statues 1998: 80. Only those who are or have been admitted to PhD-studies may be appointed to doctoral studentships. When an appointment to a doctoral studentship is made, the ability of the student to benefit from PhD-studies shall primarily be taken into account. In addition to devoting themselves to their studies, those appointed to doctoral studentships may be required to work with educational tasks, research and administration, in accordance with specific regulations in the ordinance.

Type of employment
Limit of tenure, four years according to HF 5 kap 7§. Fulltime employment with desired start according to agreement. 

 

Type of employment Temporary position
First day of employment According to agreement
Salary Monthly salary
Number of positions 1
Full-time equivalent 100
City Lund
County Skåne län
Country Sweden
Reference number PA2024/339
Contact
  • Gemma Atkinson, Research group leader, 046-2220000
  • Sofia Sönnerstedt, HR Partner, +46462229876
Union representative
  • OFR/ST:Fackförbundet ST:s kansli, 046-2229362
  • SACO:Saco-s-rådet vid Lunds universitet, kansli@saco-s.lu.se
  • SEKO: Seko Civil, 046-2229366
Last application date 05.Mar.2024 11:59 PM CET

Share links

Deadline: 2024-03-05 at 23:59
Unit: Health/Life sciences

Read the job description at the university homepage or apply.

Doctoral (PhD) student in brain and spinal cord childhood cancer

Do you want to contribute to top quality medical research?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

 

The doctoral student project and the duties of the doctoral student

We have a four-year full-time position as PhD student in our research group in Karolinska Institutet available to study childhood cancer in the brain and spinal cord. The aim of our research is to understand the processes that make these tumors so difficult to treat, and to identify possible targets for more effective treatments in the future.

We are mainly focusing our research on so-called ependymomas, which is one of the most common types of tumors in the brain and spinal cord. We compare ependymoma subtypes of different severity using multi-omics analyses of tumor samples to acquire a better understanding of the cell types present in the tumors, and the patterns of gene expression in various cell types. We are particularly interested in the cancer stem cells, the type of cells that are relatively resistant to treatment, and that give rise to recurring tumors and daughter tumors. We also culture tumor cells to be able to change their gene expression and control critical features of the cells. Tumor cells are also transplanted to mice to be able to study in detail the tumor cells over longer time periods, how they develop and change in an environment that resembles the conditions in the patient. Key questions in our research are the role of cancer stem cells, the molecular-genetic control of self-renewal of these cells, their transition in and out of quiescence and to more differentiated phenotypes.

 

As a PhD student you will learn a variety of techniques for gene expression analysis including the bioinformatical tools to analyze the data you acquire. You will use cell culture techniques, isolate cells with FACS, and apply reporter genes for this purpose. You will learn animal surgery and apply methods for stereotaxic injections to transplant tumor cells to mice, which may be monitored with magnetic resonance imaging (micro-MRI) or other imaging techniques. You will participate in designing your experiments, and most importantly, you will learn how to critically evaluate your results and relate them to previously published research data.

The research group

The Sundström research group is located in the BioClinicum research facilities of the Karolinska University Hospital. We have a long-standing interest in disorders of the brain and spinal cord, with a particular focus on stem cells in the tissue and as treatment. We are now expanding our research into the field of tumors in the brain and spinal cord, in close collaboration with the Baryawno research group at the unit for childhood cancer and surgery, Dept of Women’s and Children’s Health. We are also working closely together with other research groups at Karolinska Institutet, SciLifeLab, Royal Institute of Technology (KTH) and Stockholm University, forming a consortium on childhood diseases.

The Division of Neurogeriatrics consists of about 65 employees. The division conducts experimental and translational research related primarily to Alzheimer’s disease and other neurodegenerative diseases, but also more general molecular mechanisms with biomedical relevance are studied.

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

  1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
  2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
  3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

 

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

For this position we are looking for a student with a master degree in biology/medicine, preferably with a focus on neurobiology and/or cancer. It is advantageous but not required to have documented experience in immunofluorescence microscopy, cell culture, flow cytometry/FACS, gene expression analysis (RNA-sequencing, Spatial transcriptomics/Visium etc.), molecular cloning (plasmid design, gene editing, CRISPR screening etc.), bioinformatic analysis and/or small animal surgery. A certificate of approved FELASA education is considered a merit. If you got your master degree more than 3 years ago, it is a merit if you worked with medical/biological/biochemical research and development after your master. You must have good communication skills in English as well as collaborative skills to allow you to work closely with other PhD students and post-docs.

 

 

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

For more details of the main supervisor Dr. Xiaofei Li, and co-supervisor Dr. Erik Sundström, please see the links below

https://ki.se/en/people/xiaofei-li#publications

https://ki.se/en/people/erik-sundstrom

 

Want to make a difference? Join us and contribute to better health for all

Deadline: 2024-03-05 at 23:59
Unit: Forskargrupp Hartman

Read the job description at the university homepage or apply.

Post doc position in marine non-indigenous species and offshore windfarms

We are seeking applicants for a 3-year Post doc in marine biodiversity, to join us at the Department of ECOSCIENCE working within developing methods for monitoring, modelling, and assessing the occurrence, dispersal, and impact of non-indigenous species (NIS) in Danish seas.

Job description

The focus will be on assessment of the potential impact and risk of NIS. The tasks will include:

  • contribution to document the establishment, spread and impact of NIS in Danish seas
  • work primarily with field-based monitoring using both conventional and molecular techniques
  • Investigation of the introduction of NIS using Species Distribution Modelling (SDM) to assess the risk for dispersal via wind farm monopiles as stepping-stones in Danish seas

You will be a part of the marine group that covers research and advisory tasks across the marine environment mainly related to Danish and Arctic waters. These activities will be conducted in close collaboration with the marine biodiversity monitoring group as well as the marine model group at the department as well as external partners. It is expected that you can collaborate broadly with stakeholders such as the Danish EPA and Regional Sea Conventions (OSPAR)

Applicants should hold a PhD in marine ecology, biology, environmental sciences, or similar. We expect that you have:
 

  • Expert knowledge on NIS, species biology, benthic ecology
  • Expert knowledge on Species Distribution Modelling
  • Very good skills in the use of conventional and molecular methods for monitoring benthic biodiversity
  • Publications in high-ranking journals
  • Good collaboration skills and ability to work in an interdisciplinary team within marine science
  • Very good knowledge of English (written and oral)
  • Good communication skills (scientific community, the public, stakeholders, and managers)
  • Experience in data analysis and statistical tools
  • Preferable experience with advisory work

Who we are

The Department of Ecoscience is engaged in research programs and advisory work covering the major biological subdisciplines. We conduct world-class research in the areas of aquatic biology and ecology, Arctic environment and ecosystems, biodiversity, conservation biology and wildlife management. The Department currently employs approximately 275 academic and technical staff, as well as many PhD students.

The successful candidate will work in a dynamic and internationally engaged scientific environment at the Section for Marine diversity and experimental ecology (for more information see: AU Ecoscience – Research in Marine Diversity and Experimental Ecology).

The department is, and wishes to continue to be, an active, dynamic and inspiring workplace with exciting challenges, enthusiastic colleagues and academic opportunities for development. The department wishes to support employees in creating a good balance between their work and home lives and to maintain and attract talented and committed staff, where freedom, creativity and respect for the long-term perspective are core values. For more information on the Department see: http://ecos.au.dk/en/.

What we offer

The department offers:

  • a well-developed research infrastructure, laboratories and access to shared equipment
  • an exciting interdisciplinary environment with many national, international and industrial collaborators
  • a research climate encouraging lively, open and critical discussion within and across different fields of research
  • a workplace characterised by professionalism, equality and a healthy work-life balance.

Expected start date and duration of employment

This is a 3–year position from 1. June 2024 or as soon as possible.
This is a fixed-term position to end on 31 May 2027.

Place of work and area of employment

The place of work is Frederiksborgvej 399, 4000 Roskilde, Denmark, and the area of employment is Aarhus University with related departments. 

Contact information

For further information, please contact professor Peter Stæhr pst@ecos.au.dk +45 50 42 74 02
 

Application procedure

Shortlisting is used. This means that after the deadline for applications – and with the assistance from the assessment committee chairman, and the appointment committee if necessary, – the head of department selects the candidates to be evaluated. All applicants will be notified whether or not their applications have been sent to an expert assessment committee for evaluation. The selected applicants will be informed about the composition of the committee, and each applicant is given the opportunity to comment on the part of the assessment that concerns him/her self. Once the recruitment process is completed a final letter of rejection is sent to the deselected applicants.

Letter of reference

If you want a referee to upload a letter of reference on your behalf, please state the referee’s contact information when you submit your application. We strongly recommend that you make an agreement with the person in question before you enter the referee’s contact information, and that you ensure that the referee has enough time to write the letter of reference before the application deadline.
Unfortunately, it is not possible to ensure that letters of reference received after the application deadline will be taken into consideration.

Formalities and salary range

Technical Sciences refers to the Ministerial Order on the Appointment of Academic Staff at Danish Universities under the Danish Ministry of Science, Technology and Innovation.

The application must be in English and include a curriculum vitae, degree certificate, a complete list of publications, a statement of future research plans and information about research activities, teaching portfolio and verified information on previous teaching experience (if any). Guidelines for applicants can be found here.

Appointment shall be in accordance with the collective labour agreement between the Danish Ministry of Taxation and the Danish Confederation of Professional Associations. Further information on qualification requirements and job content may be found in the Memorandum on Job Structure for Academic Staff at Danish Universities.

Salary depends on seniority as agreed between the Danish Ministry of Taxation and the Confederation of Professional Associations.

Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.

Research activities will be evaluated in relation to actual research time. Thus, we encourage applicants to specify periods of leave without research activities, in order to be able to subtract these periods from the span of the scientific career during the evaluation of scientific productivity.

Aarhus University offers a broad variety of services for international researchers and accompanying families, including relocation service and career counselling to expat partners. Read more here. Please find more information about entering and working in Denmark here.

Aarhus University also offers a Junior Researcher Development Programme targeted at career development for postdocs at AU. You can read more about it here.

The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.

 

Deadline: 2024-03-08 at 23:59
Unit: Department of Ecoscience – Applied Marine Ecology and Modelling – Faculty: Technical Sciences
Email: mailto:pst@ecos.au.dk
Phone: +4550427402

Read the job description at the university homepage or apply.

Postdoc in infection neuroscience

The Department of Biomedicine at Faculty of Health at Aarhus University invites applications for a position as Postdoc in infection neuroscience as per 1 July 2024 or as soon as possible thereafter. The position is a fixed-term full-time position for 36 months.

About the research project

Viral infections in the brain can have fatal outcomes if not controlled by the immune system. At the same time, the immune response can also cause both acute and long-term damage to the brain. Therefore, there is an increasing appreciation of the role of the immune system in acute infections, post-infectious brain conditions, and neurodegenerative diseases. Despite this interest, the mechanisms involved remain poorly understood. This project aims to uncover novel immunological mechanisms underpinning post-infectious brain conditions and neurodegenerative diseases.

Your job responsibilities

As Postdoc in infection neuroscience your position is primarily research-based but may also involve teaching assignments. You will contribute to the development of the department through research of high international quality, including publication. In your daily work, you will work closely with colleagues on your project, where you will receive supervision and guidance.

You will report to Professor Søren Riis Paludan.

Your competences

You have academic qualifications at PhD level in the area of neuroscience and may also have experience in or a strong interest to learn about immunology. We are looking for a person with practical experience in mouse models in neuroscience or neuropathology, and relevant associated methodologies; hence, FELASA-B qualification is a plus.

Highly desirable additional skills (though not essential) include at least two of the following methods:

  • calcium imaging
  • electrophysiology (intra- or extracellular recording)
  • intracerebral injections
  • microdissection of the CNS regions
  • immunohistochemistry
  • quantitative confocal microscopy
  • behavioral assessment
  • single-molecule RNA hybridization.

As a person, you are ambitious, take ownership of and responsibility for your work, and possess good communication and interpersonal skills. You are inclusive and team-oriented and able to contribute to a good work environment. We expect you to be fluent in oral and written English.

In order to be considered qualified for a postdoc position, you must meet these academic criteria.

Shortlisting will be used.

The Department of Biomedicine

The department of Biomedicine prioritises diversity and a good work environment, as this is a prerequisite for groundbreaking research. In a diverse and international research environment, dedicated employees are looking to generate new knowledge within biomedical research areas such as infection and inflammation, membranes, neuroscience, and personalised medicine. The Department of Biomedicine provides research-based teaching of the highest quality and is responsible for a large part of the medical degree programme. Academic staff contribute to the teaching. English is the preferred language in the laboratory, at meetings and at seminars. The department employs approx. 500 people from all over the world, and they make use of the department's modern laboratory-, core- and animal facilities. The Department of Biomedicine focuses on innovation, entrepreneurship and collaboration with business and industry, and numerous researchers from the department have established companies to develop new medicinal treatments founded in professional scientific basic research. You can read more about the department here and about the faculty here.

The host laboratory

The laboratory of Professor Søren Paludan is interested in understanding early immune responses against viral infections, with a focus on the central nerve system (CNS). We use a broad range of experimental systems, ranging from molecular screening tools, state-of-the-art methods for molecular/cellular characterization, animal models, and primary human cell/organoid models. We offer a unique environment to perform this project by combining multidisciplinary research teams, skilled technical staff, biosafety level 2+ laboratories to manipulate viral vectors, and state-of-the-art facilities to study CNS-virus interactions at the molecular, cellular, functional, and behavioural level.

We have a very international environment, with more than half of all lab members from a non-Danish background. You should be fluent in oral and written English, which is the preferred language in the laboratory, at meetings and in seminars. Our core values are high ambitions, a collaborative and friendly culture, and development of talent.

The laboratory is part of the Center for Immunology of Viral Infections Center or Immunology of Viral Infections (CiViA).

Questions about the position

If you have any questions about the position, please contact professor Søren Paludan, email srp@biomed.au.dk, or telephone no. +45 2899 2066, or associate professor Line Reinert, email line.reinert@biomed.au.dk, or telephone no. +45 3064 2210.

Your place of work will be the Department of Biomedicine, Høegh-Guldbergs Gade 10, DK-8000 Aarhus C, Denmark.

We expect to conduct interviews in the beginning of May 2024.

Terms of employment

Application

Your application must include the following:

  • Motivated application
  • Curriculum Vitae
  • Diploma
  • Template for applicant – postdoc
  • A list of publications
  • A teaching portfolio. We refer to Guideline on the use of teaching portfolios
  • A maximum of five of the publications of greatest relevance to the job may be submitted (optional)
  • Research plan can be uploaded (optional)
  • Coauthor statement(s) can be uploaded (optional)
  • References/recommendations can be uploaded separately in the e-recruitment system (optional)

We refer to the faculty’s Guidelines for applicants.

Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.

Letter of reference

If you want a referee to upload a letter of reference on your behalf, please state the referee’s contact information when you submit your application. We strongly recommend that you make an agreement with the person in question before you enter the referee’s contact information, and that you ensure that the referee has enough time to write the letter of reference before the application deadline.
Unfortunately, it is not possible to ensure that letters of reference received after the application deadline will be taken into consideration.

International applicant?

Aarhus University offers a broad variety of services for international researchers and accompanying families, including assistance with relocation and career counselling to expat partners. Please find more information about the International Staff Office and the range of services here. Aarhus University also has a Junior Researcher Association and offers career development support. You can read more about these resources here.

The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.
 

Deadline: 2024-03-28 at 23:59
Unit: Department of Biomedicine – Forsk. & udd., Skou-bygningen – Faculty: Health
Email: mailto:srp@biomed.au.dk
Phone: +4528992066

Read the job description at the university homepage or apply.

Postdoctoral Fellow in immunologi.

The Department of Molecular Biosciences, Wenner-Gren Institute (MBW) conducts experimental basic research in molecular cell biology, intergrative biology and infection and immune biology. The research environment is characterized by a modern and advanced methodology and has a strong international profile. MBW is one of the larger departments of the Faculty of Science at Stockholm University with more than 30 research groups and about 200 employees, of whom about 60 are doctoral students. Read more about MBW at www.su.se/mbw.

Project description
The position is connected to Professor Eva Sverremark-Ekström’s research group and will mainly be associated with a new collaborative research project between two research groups at Stockholm university and Region Stockholm, where we aim to investigate underlying immune- and epigenetic mechanisms in cardiovascular disease. The project is based on in vitro work on material from clinical cohorts.

Main responsibilities
We are looking for a highly motivated and focused candidate who is a good team worker, yet with an ability to work independently. The successful applicant will utilize state-of-the-art approaches aimed at obtaining a fundamental molecular understanding of how immune- and epigenetic processes contribute to the development of cardiovscular disease, but also inflammatory conditions in general. The candidate will mainly work with material from human primary cells and needs to be proficient in methods such as ELISA and immune array-based techniques, as well as familiar with transcriptome analyses (RNA-seq) and epigenetic analyses (e.g., ChIP, ChIP-seq, ATAC-seq) as well as with the handling and processing of data generated from these large-scale analyses.

Qualification requirements
Postdoctoral positions are appointed primarily for purposes of research. Applicants are expected to hold a Swedish doctoral degree or an equivalent degree from another country.

Assessment criteria
The degree must have been completed at latest before the employment decision is made, but no more than three years before the closing date. An older degree may be acceptable under special circumstances. Special reasons refer to sick leave, parental leave, elected positions in trade unions, service in the total defense, or other similar circumstances as well as clinical attachment or service/assignments relevant to the subject area.

In the appointment process, special attention will be given to research skills in immunology in combination with molecular biology and the expertise in the methods mentioned above. Excellent English language skills, both written and spoken, are a requisite. Laboratory supervision of students is a merit. An ability to communicate in Swedish is a further merit, as the project involves contact with people in the hospital where English is not used on a routine basis.

Terms of employment
The position involves full-time employment for a minimum of two years and a maximum of three years, with the possibility of extension under special circumstances. Start date 2024-04-15 or as per agreement.

Stockholm University strives to be a workplace free from discrimination and with equal opportunities for all.

Contact
Further information about the position can be obtained from Professor Eva Sverremark-Ekström, telephone: +46 8 16 41 78, eva.sverremark@su.se.

Union representatives
Ingrid Lander (Saco-S), telephone: +46 708 16 26 64, saco@saco.su.se, Alejandra Pizarro Carrasco (Fackförbundet ST/OFR), telephone: +46 8 16 34 89, alejandra@st.su.se, and seko@seko.su.se (SEKO).

Application
Apply for the position at Stockholm University’s recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline.

Please include the following information with your application

  • Your contact details and personal data
  • Your highest degree
  • Your language skills
  • Contact details for 2–3 references

and, in addition, please include the following documents

  • Cover letter
  • CV – degrees and other completed courses, work experience and a list of publications
  • Research proposal (no more than 3 pages) describing:
    – why you are interested in the field/project described in the advertisement
    – why and how you wish to complete the project
    – what makes you suitable for the project in question
  • Copy of PhD diploma
  • Letters of recommendation (no more than 3 files)
  • Publications in support of your application (no more than 3 files).

The instructions for applicants are available at: How to apply for a position.

You are welcome to apply!

Stockholm University contributes to the development of sustainable democratic society through knowledge, enlightenment and the pursuit of truth.

Deadline: 2024-03-10 at 23:59
Unit: Health/Life sciences

Read the job description at the university homepage or apply.

Postdoc in innate antiviral immunology

The Department of Biomedicine at Faculty of Health at Aarhus University invites applications for a position as Postdoc in innate antiviral immunology as per 1 July 2024 or as soon as possible thereafter. The position is a fixed-term full-time position for 36 months.

About the research project

The first line of defense against viral infections is essential for prevention of disease development. Epithelial surfaces represent a major portal of entry for viral infections; yet, we have limited knowledge on the mechanisms that govern this first line of host defense. This project will take a genome-wide screening approach to identify novel genes/proteins and mechanisms involved in exerting early restriction of virus replication in epithelial cells.

Your job responsibilities

As Postdoc in innate antiviral immunology your position is primarily research-based but may also involve teaching assignments. You will contribute to the development of the department through research of high international quality, including publication. In your daily work, you will work closely with colleagues on your project, where you will receive supervision and guidance.

You will report to Professor Søren Riis Paludan.

Your competences

You have academic qualifications at PhD level within the area of virology or immunology and have experience with large screening set-ups. Alternatively, you have significant experience with large screening set-ups, and are highly motivated to apply this expertise to solve a question in infection immunology.

Specifically, desirable skills include:

  • management and development of innovative research projects to the highest level
  • CRISPR screens
  • lentivirus work
  • biochemical and cell biological assays in virology/immunology
  • quantitative confocal microscopy
  • flow cytometry

As a person, you are ambitious, take ownership of and responsibility for your work, and possess good communication and interpersonal skills. You are inclusive and team-oriented and able to contribute to a good work environment. We expect you to be fluent in oral and written English.

In order to be assessed as qualified for a Postdoc position, you must meet these academic criteria.

Shortlisting will be used.

The Department of Biomedicine

The department of Biomedicine prioritises diversity and a good work environment, as this is a prerequisite for groundbreaking research. In a diverse and international research environment, dedicated employees are looking to generate new knowledge within biomedical research areas such as infection and inflammation, membranes, neuroscience and personalised medicine. The Department of Biomedicine provides research-based teaching of the highest quality and is responsible for a large part of the medical degree programme. Academic staff contribute to the teaching. English is the preferred language in the laboratory, at meetings and at seminars. The department employs approx. 500 people from all over the world, and they make use of the department's modern laboratory-, core- and animal facilities. The Department of Biomedicine focuses on innovation, entrepreneurship and collaboration with business and industry, and numerous researchers from the department have established companies to develop new medicinal treatments founded in professional scientific basic research. You can read more about the department here and about the faculty here.

The host laboratory

The laboratory of Professor Søren Paludan is interested in understanding early immune responses against viral infections, with a focus on epithelial surfaces and the central nerve system (CNS). We use a broad range of experimental systems, ranging from molecular screening tools, state-of-the-art methods for molecular/cellular characterization, animal models, and primary human cell/organoid models. We offer a unique environment to perform this project with multidisciplinary research teams, expertise in genome-wide CRISPR screens, skilled technical staff, biosafety level 2+ laboratories, and a broad methodological set-up, thus allowing to fully develop the project from gene identification, via mechanistic exploration, to the characterization of antiviral defense roles in vivo.

We have a very international environment, with more than half of all lab members from a non-Danish background. You should be fluent in oral and written English, which is the preferred language in the laboratory, at meetings and in seminars. Our core values are high ambitions, a collaborative and friendly culture, and development of talent.

The laboratory is part of the Center for Immunology of Viral Infections Center or Immunology of Viral Infections (CiViA).

Questions about the position

If you have any questions about the position, please contact Professor Søren Paludan, email srp@biomed.au.dk or telephone no. +45 2899 2066.

Your place of work will be the Department of Biomedicine, Høegh-Guldbergs Gade 10, DK-8000 Aarhus C, Denmark.

We expect to conduct interviews in the beginning of May 2024.

Terms of employment

Application

Your application must include the following:

  • Motivated application
  • Curriculum Vitae
  • Diploma
  • Template for applicant – postdoc
  • A list of publications
  • A teaching portfolio. We refer to Guideline on the use of teaching portfolios
  • A maximum of five of the publications of greatest relevance to the job may be submitted (optional)
  • Research plan can be uploaded (optional)
  • Coauthor statement(s) can be uploaded (optional)
  • References/recommendations can be uploaded separately in the e-recruitment system (optional)

We refer to the faculty’s Guidelines for applicants.

Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.

Letter of reference

If you want a referee to upload a letter of reference on your behalf, please state the referee’s contact information when you submit your application. We strongly recommend that you make an agreement with the person in question before you enter the referee’s contact information, and that you ensure that the referee has enough time to write the letter of reference before the application deadline.
Unfortunately, it is not possible to ensure that letters of reference received after the application deadline will be taken into consideration.

International applicant?

Aarhus University offers a broad variety of services for international researchers and accompanying families, including assistance with relocation and career counselling to expat partners. Please find more information about the International Staff Office and the range of services here. Aarhus University also has a Junior Researcher Association and offers career development support. You can read more about these resources here.

The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.
 

Deadline: 2024-03-28 at 23:59
Unit: Department of Biomedicine – Forsk. & udd., Skou-bygningen – Faculty: Health
Email: mailto:srp@biomed.au.dk
Phone: +4528992066

Read the job description at the university homepage or apply.

PhD fellowship in Neuroscience at the Department of Neuroscience

We are offering a PhD fellowship in neuroscience commencing 16 June 2024 or as soon as possible hereafter.

Our group and research
The PhD will be done in collaboration between the Perrier lab https://in.ku.dk/research/perrier-lab/ investigating how mutations detected in the brain of human patients affect the behavior of neuronal networks, and the Berg lab https://in.ku.dk/research/berg-lab/ combining quantitative approaches of mathematics and physics with experiments using electrophysiology to better understand the nervous system.

The Perrier and Berg groups are characterized by teamwork and strong support among team members. The teams are highly interdisciplinary and international, and we welcome team members of any nationality, gender, and age. The Perrier group (8-9 members) is using electrophysiology, calcium imaging, behaviour-assessment for understanding how mutations affect brain function especially at microcircuit levels (see Dos Santos et al., Cell Rep Med. 2023 Dec 19;4(12):101308. doi: 10.1016).

The two groups are in the vibrant research environment of Department of Neuroscience at University of Copenhagen, Denmark. Information on the department can be found at: https://in.ku.dk/

Project description

During the PhD study, the student will be Investigating the relationship between excitation and inhibition in the neocortex of wild type mice and mice carrying specific mutations responsible for neurodevelopmental encephalopathy. Data suggest that the mutation affects the behaviour of feedforward and feedback inhibition cortical microcircuits. In this research project, the student will test this hypothesis using high-density multielectrode arrays (Neuropixels 2.0 probes) combined with optotagging of virally expressed opsins in cortical interneurons and pyramidal neurons. The animal behaviour will be closely monitored using videography combined with the electrophysiology recordings. Computational analysis of data will take place using available software (Kilosort and Phy) in MATLAB, python along with custom-developed code for the experiments. The behaviour will be analysed using the video-recorded material and deep neural network via available software such as Deeplabcut and Cebra.

Principal supervisors are:

Jean-François Perrier, Associate Professor (Professor promotion program), Department of Neuroscience, perrier@sund.ku.dk, tel. +45 23 81 29 46.

Rune Berg, Associate Professor (Professor promotion program), Department of Neuroscience, runeb@sund.ku.dk, tel. +45 26 97 73 94

Start: 16 June 2024 

Duration: 3 years as a PhD student + 3 months as research assistant for enrolment

Job description
Your key tasks as a PhD student at SUND are:

  • Carrying through an independent research project under supervision.
  • Completing PhD courses or other equivalent education corresponding to approximately 30 ECTS points.
  • Participating in active research environments including a stay at another research team.
  • Obtaining experience with teaching or other types of dissemination related to your PhD project
  • Teaching and disseminating your knowledge.
  • Writing a PhD thesis on the grounds of your project

Key criteria for the assessment of applicants
Applicants must have qualifications corresponding to a master’s degree related to the subject area of the project, e.g. Master in Neuroscience or Signal Processing. Please note that your master’s degree must be equivalent to a Danish master’s degree (two years).

Other important criteria are:

  • You have experience in electrophysiology (in vitro or in vivo)
  • You have experience in programming (e.g., Python, Matlab)
  • You have a curious mind-set with a strong interest in problem solving.
  • You are enthusiastic, highly motivated and a self-starter
  • You have experience in lab work with good laboratory practices.
  • You are fluent in English (written and spoken)

Place of employment

The place of employment is at the Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen. We offer creative and stimulating working conditions in dynamic and international research environment. Our research facilities include modern laboratories in the new ‘Mærsk Tower’, https://maersktower.ku.dk/

Terms of employment
The average weekly working hours are 37 hours per week.

The position is a fixed-term position limited to a period of 3 years. The start date is 16 June 2024 or after agreement.

The employment is conditioned upon the applicant’s success­ful enrolment as a PhD student at the Graduate School at the Faculty of Health and Medical Sciences, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant during an initial three-month employment as a research assistant.

The PhD study must be completed in accordance with The Ministerial Order on the PhD programme (2013) and the Faculty’s rules on achieving the degree.

Salary, pension and terms of employment are in accordance with the agree­ment between the Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary starts at approximately 27,800 DKK/Roughly 3,700 EUR (October 2021 level) plus pension.

Questions
For specific information about the PhD fellowship, please contact the principal supervisor.

General information about PhD studies at the Faculty of Health and Medical Sciences is available at the Graduate School’s website: https://healthsciences.ku.dk/phd/guidelines/

Application procedure
Your application must be submitted electronically by clicking ‘Apply now’ below. The application must include the following documents in PDF format: 

1. Motivated letter of application (max. one page)

2. CV incl. education, experience, language skills and other skills relevant for the position

3. Certified copy of original Master of Science diploma and transcript of records in the original language, including an authorized English translation if issued in other language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted. As a prerequisite for a PhD fellowship employment, your master’s degree must be equivalent to a Danish master’s degree. We encourage you to read more in the assessment database: https://ufm.dk/en/education/recognition-and-transparency/find-assessments/assessment-database. Please note that we might ask you to obtain an assessment of your education performed by the Ministry of Higher Education and Science

4. Publication list (if possible)

Application deadline:  28 February 2024, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor.

The assessor makes a non-prioritized assessment of the academic qualifications and experience with respect to the above-mentioned area of research, techniques, skills and other requirements listed in the advertisement.

Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You find information about the recruitment process at: https://employment.ku.dk/faculty/recruitment-process/

The applicants will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

The University of Copenhagen wish to reflect the diversity of society and encourage all qualified candidates to apply regardless of personal background. 

Deadline: 2024-02-28 at 23:59
Unit: Health/Life sciences

Read the job description at the university homepage or apply.

Postdoctoral position in automation for reflectometry at liquid surfaces (PA2024/419)

Lunds universitet, LTH, Kemiska institutionen (LTH)

Lund University was founded in 1666 and is repeatedly ranked among the world’s top universities. The University has around 45 000 students and more than 8 000 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition.

Lund University welcomes applicants with diverse backgrounds and experiences. We regard gender equality and diversity as a strength and an asset.

Description of the workplace

This project is a collaboration between Prof Karen Edler (Lund University), Dr Tom Arnold (ESS), Prof Bridget Murphy (Kiel, Germany) and Dr Chen Shen (DESY, Hamburg, Germany).

The Edler research group in the Centre for Analysis and Synthesis (CAS) aims to understand self-organisation in a range of materials primarily using scattering techniques. This project will explore surfactant assembly at the interfaces of deep eutectic solvent solutions using neutron and X-ray reflectivity and will primarily focus on the design and build of an automated sample changer to facilitate these experiments. The sample changer will be designed to be used at the FREIA instrument at the ESS neutron source, and to be compatible with the X-ray reflectivity beamline at the DESY synchrotron.

 

Subject description

This project will study amphiphiles at the air-solution interface in deep eutectic solvents to better understand emulsification and gelation in these novel green solvents. We will use neutron and X-ray reflectivity to characterise the interfaces in these systems as well as measurements of surface tension, interfacial rheology, emulsification tests and studies of the solid-liquid interface using QCM-D.

To facilitate the neutron reflectivity experiments on these systems, we aim to automate sample preparation, to improve reproducibility, especially of small volume samples. Therefore, this postdoc will also take part in the design and build of an automated/robotic sample changer for free-liquid sample environments and contribute towards enhanced software and reproducible data processing of high-throughput and time resolved studies.

 

Work duties

The main duties involved in a post-doctoral position is to conduct research. Teaching may also be included, but up to no more than 20% of working hours. The position includes the opportunity for three weeks of training in higher education teaching and learning. The purpose of the position is to develop the independence as a researcher and to create the opportunity of further development.

You will develop and test dispensing technology for viscous DES/amphiphile solutions, contribute to the design of the complete sample changing system, coordinate this work with ESS & DESY, participate in neutron and X-ray experiments and will take the primary responsibility for investigating amphiphile-DES systems. You will work in the Edler group labs in CAS, at Lund University but will also spend a substantial amount of time working at the ESS, with the technical team and Dr Arnold, to assist with building and installing the robotic sample changer on FREIA. Travel to Germany to work with our collaborators at DESY and in Kiel, as well as to attend neutron and synchrotron X-ray reflectivity experiments at the ILL, ISIS, Diamond and ESRF will also be required.

Work duties will include:

  • Assisting with the technical design and construction of a robotic/automatic sample changer for neutron reflectivity on open liquid samples.
  • Research on amphiphile self-assembly in deep eutectic solvents
  • Travel to neutron and synchrotron x-ray facilities to carry out neutron /X-ray reflectivity experiments.
  • Travel to Kiel and Hamburg for project meetings and to work with our collaborators on this project.
  • Teaching in the first, second and third cycles of studies.
  • Supervision of degree projects and doctoral students.
  • Actively seeking beamtime and external research funding.
  • Administration related to the work duties listed above.

 

Qualification requirements

Appointment to a post-doctoral position requires that the applicant has a PhD, or an international degree deemed equivalent to a PhD, within the subject of the position. The certificate proving the qualification requirement is met, must be received before the employment decision is made. Priority will be given to candidates who have graduated no more than three years ago before the last day for application. Under special circumstances, the doctoral degree can have been completed earlier.

Requirements:

  • PhD in materials, physical chemistry or related subjects including some background in chemical characterisation and safe working in a laboratory setting is required.
  • Experience with and understanding of techniques to study amphiphile solutions at interfaces, such as X-ray and neutron reflectivity, ellipsometry, QCM-D is required.
  • Proficiency in using suitable software for X-ray or neutron reflectivity data analysis is required.
  • Very good oral and written proficiency in English.

Additional requirements:

  • Experience of working with deep eutectic solvents and/or ionic liquids is desirable.
  • Programming skills, particularly in Python, or any experience with motion control would be advantageous.
  • Experience in building or maintaining complex scientific equipment, particularly for X-ray or neutron scattering/reflectivity is desirable.
  • Ability to prepare research proposals, to conduct individual research work and to disseminate results by publication or presentations.
  • Ability to organise and prioritise own workload to meet required deadlines.

 

Assessment criteria

This is a career development position primarily focused on research. The position is intended as an initial step in a career, and the assessment of the applicants will primarily be based on their research qualifications and potential as researchers. Particular emphasis will be placed on research skills within the subject.

For appointments to a post-doctoral position, the following shall form the assessment criteria:

  • A good ability to develop and conduct high quality research.
  • Demonstrated potential to publish in high quality, peer reviewed journals.
  • Teaching skills.

Other qualifications:

  • Experience in collecting X-ray and/or neutron scattering (particularly reflectometry) data and in using modelling techniques and software to analyse scattering data.
  • Experience in design and build of complex scientific equipment, particularly including motion control.
  • Experience in working with deep eutectic solvents or other viscous colloidal solutions.
  • Strong proficiency in spoken and written English.

Consideration will also be given to how the applicant’s experience and skills complement and strengthen ongoing research within the department, and how they stand to contribute to its future development.

 

We offer

Lund University is a state authority, which means you get special benefits, generous holidays and a favorable occupational pension. 

Read more on the university’s website about working with us. https://www.lu.se/om-universitetet/jobba-hos-oss

 

Further information

This is a full-time, fixed-term employment of 3 years. Start date 2024-03-31 or as agree. The period of employment is determined in accordance with the agreement “Avtal om tidsbegränsad anställning som postdoktor” (“Agreement on fixed-term employment as a post-doctoral fellow”).

 

How to apply

Applications are to be submitted via the University’s recruitment system. Applications shall be written in English and be compiled into a PDF-file containing:

  • a cover letter stating the reasons why you are interested in the position and how the research project corresponds to your interests and research background,
  • résumé/CV, including a list of publications,
  • contact information of at least two references,
  • copy of the doctoral degree certificate or equivalent,
  • any other document to which you would like to draw attention (copies of grade transcripts, letters of recommendation, etc.)  

Welcome to apply!

Type of employment Temporary position
Contract type Full time
First day of employment 2024-03-31 or as agreed
Number of positions 1
Full-time equivalent 100
City Lund
County Skåne län
Country Sweden
Reference number PA2024/419
Contact
  • Karen Edler, karen.edler@chem.lu.se
  • Erik Andersson Jardby, erik.andersson_jardby@kilu.
Union representative
  • OFR/ST:Fackförbundet ST:s kansli, 046-2229362
  • SACO:Saco-s-rådet vid Lunds universitet, kansli@saco-s.lu.se
Last application date 12.Mar.2024 11:59 PM CET

Share links

Deadline: 2024-03-12 at 23:59
Unit: Health/Life sciences

Read the job description at the university homepage or apply.

PhD fellowship in plant-microbiome assembly

The Department of Biology, Section of Microbiology invites applicants for a PhD fellowship to study social interactions in the plant root microbiome.

Start date is (expected to be) 1 August 2024 or as soon as possible thereafter.

The project

Novel strategies for eco-friendly and sustainable food production seek to explore and exploit the potential of the plant microbiome to promote growth, acquire nutrients, and induce resistance against pests and pathogens.  Yet, we lack a fundamental understanding of the ecological factors controlling the establishment of a beneficial plant microbiome. Hence, we seek to test the ecological and evolutionary role of microbe-microbe interaction in the assembly and maturation of complex plant root microbiomes.

This project investigates the role of microbial interactions as key drivers for microbiome composition and activity, specifically focussing on interspecies cooperation/competition and the resulting priority effects. We work with the overarching hypothesis that microbial communities are composed of collaboromes, rather than independent species, that are characterized by being microscale focal points of interdependent bacteria showing essential microbe-microbe interactions. The emergent properties of these collaboromes present many beneficial consequences for plant growth and health.

The experimental design of this project goes beyond simple co-occurrence in bulk microbiome samples. Instead, it focuses on co-occurrence network analysis on microscale samples, which is complemented with detailed co-localization analyses to identify putative interactions. Finally, selected identified putative interactions are experimentally validated in simple microcosm experiments

Who are we looking for?

We are seeking a highly motivated and ambitious individual with good interpersonal and communication skills. Highly desired candidates will have a solid theoretical background in plant-microbiome interactions. As well as practical experience with techniques in microbiology and molecular biology. A strong interest in bioinformatics and/or bioimaging is also considered advantageous. 

Applicants should hold an MSc degree in Plant Biology, Microbiology, Bioinformatics, Biochemistry, Biotechnology, or similar with good results and good English skills. As criteria for the assessment of your qualification emphasis will also be laid on previous publications (if any) and relevant work experience. The MSc degree must be awarded prior to the employment date.

Our group and research- and what do we offer?

The PhD fellow will be part of the Section of Microbiology, headed by Prof. Søren Sørensen. His research group focuses on social interactions in microbial populations in in-vivo systems such as soils, plants, animals, and humans. The section houses state-of-the-art both culture-dependent and culture-independent experimental infrastructure that enables us to examine how microbes interact at a scale that is relevant for such small organisms and study the roles of the individual species in these interactions. To do so we use techniques such as high throughput sequencing, flow cytometry, ultra-high resolution bioimaging, confocal microscopy, and microbial reporter systems, combined with the reductionist synthetic community approaches, allowing in-depth investigation of the microbe-microbe or host-microbe interactions mechanism.

The Section offers a highly diverse and inclusive environment consisting of ≈35 researchers who specialize in microbial community interactions, mobile genetic elements, horizontal gene transfer, and the early life human microbiome. The group has gained an international reputation for applying a combination of bioinformatics and molecular biology approaches to address research questions of ecological, clinical, and biotechnological interest, which lie at the intersection of computational biology, genomics, and bacterial evolution.

The group is a part of the Department of Biology, Faculty of SCIENCE, University of Copenhagen. We are located in Copenhagen.

Principal supervisor is Professor Søren Sørensen (sjs@bio.ku.dk ), Section of Microbiology, Department of Biology. The student will be co-supervised by Dr. Ke Tao (ke.tao@bio.ku.dk).

The PhD programme

Qualifications needed for the PhD programme
To be eligible for the regular PhD programme, you must have completed a degree programme, equivalent to a Danish master’s degree (180 ECTS/3 FTE BSc + 120 ECTS/2 FTE MSc) related to the subject area of the project, e.g. Plant Biology, Microbiology, Bioinformatics, Biochemistry, Biotechnology, or similar. For information of eligibility of completed programmes, see General assessments for specific countries and Assessment database.

Terms of employment in the PhD programme
Employment as PhD fellow is full time and for maximum 3 years.

Employment is conditional upon your successful enrolment as a PhD student at the PhD School at the Faculty of SCIENCE, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant.

Terms of appointment and payment accord to the agreement between the Danish Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. The position is covered by the Protocol on Job Structure.

Responsibilities and tasks in the PhD programme

  • Carry through an independent research project under supervision
  • Complete PhD courses corresponding to approx. 30 ECTS / ½ FTE
  • Participate in active research environments, including a stay at another research institution, preferably abroad
  • Teaching and knowledge dissemination activities
  • Write scientific papers aimed at high-impact journals
  • Write and defend a PhD thesis on the basis of your project

 

We are looking for the following qualifications:

  • Professional qualifications relevant to the PhD project
  • Relevant publications
  • Relevant work experience
  • Other relevant professional activities
  • Curious mind-set with a strong interest in plant-microbiome interactions
  • Good language skills

 

Nice-to-have qualifications:

  • Experience with plant experimental work, including cultivation, maintenance, and site-specific sampling of microbial communities in the rhizosphere; rhizoplane, and endosphere.
  • Experience with any or all of the following methodologies: FISH detection in combination with CLSM microscope imaging and FACS analyses, molecular cloning, preparation of sequencing libraries (Illumina, PacBio, ONT), and analysis of sequencing data.

 

 

***************************************************************************

Application and Assessment Procedure

 Your application including all attachments must be in English and submitted electronically by clicking APPLY NOW below.

Please include

  1. Motivated letter of application (max. one page)
  2. Curriculum vitae including information about your education, experience, language skills and other skills relevant for the position
  3. Original diplomas for Bachelor of Science or Master of Science and transcript of records in the original language, including an authorized English translation if issued in another language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted.
  4. Publication list (if possible)
  5. Reference letters (if available)

Application deadline:

The deadline for applications is Tuesday 27 February 2024, 23:59 GMT +1.

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After deadline, a number of applicants will be selected for academic assessment by an unbiased expert assessor. You are notified, whether you will be passed for assessment.

The assessor will assess the qualifications and experience of the shortlisted applicants with respect to the above mentioned research area, techniques, skills and other requirements. The assessor will conclude whether each applicant is qualified and, if so, for which of the two models. The assessed applicants will have the opportunity to comment on their assessment. You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/.

 

Interviews with selected candidates are expected to be held in week early to mid May 2024.

Questions
For specific information about the PhD fellowship, please contact the principal supervisor or the co-supervisor.

General information about PhD study at the Faculty of SCIENCE is available at the PhD School’s website: https://www.science.ku.dk/phd/.

The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position. 

Deadline: 2024-02-27 at 23:59
Unit: Health/Life sciences

Read the job description at the university homepage or apply.

PhD student in Tumor Microenvironment – Oncology (PA2024/435)

Lund University, Faculty of Medicine, Department of Clinical Sciences, Lund

Lund University was founded in 1666 and is repeatedly ranked among the world’s top universities. The University has around 45 000 students and more than 8 000 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition.

Lund University welcomes applicants with diverse backgrounds and experiences. We regard gender equality and diversity as a strength and an asset.

Division of Tumor Microenvironment
The research group conducts translational studies in the field of brain tumors. A central part of this work requires coworkers with special expertise in advanced proteomics and tumor biology. The activities are conducted by doctors, doctoral students, nurses, postdoctoral researchers, research engineers and assistant researchers in the Kamprad Building, SUS Lund, in an environment with several research groups in cancer research.  

Within the Division we aim to maintain a good working environment based on mutual respect and consideration. We constantly strive to improve the conditions for work, development, and participation for all employees. 

The research group is now looking for a driven and motivated candidate for PhD studies. The position is a full-time employment for 48 months. The proposed starting date is 1 April 2024 or upon agreement. 

We offer
Lund University is a public authority, which means that employees get benefits, generous annual leave and an advantageous occupational pension scheme. Read more on the University website about being a Lund University employee: Work at Lund University

Work assignments
PhD studies in project “The tumor microenvironment of malignant brain tumors”.

The work duties include experimental work and analysis of clinical samples and primary tumor cell model systems. More specifically, the aim is to identify internalizing surface antigens for antibody-based targeting of the tumor niche and to study the role of macrophages and T cells in tumor development. The results are expected to form the basis of a doctoral thesis.

Qualifications

  • A university degree or equivalent foreign education in medicine, biomedicine or molecular biology is a requirement.
  • Experience of working with immune cells (macrophages, T cells, etc.).
  • Good communication and collaboration skills.

 

Eligibility
Students with basic eligibility for third-cycle studies are those who- have completed a second-cycle degree- have completed courses of at least 240 credits, of which at least 60 credits are from second-cycle courses, or- have acquired largely equivalent knowledge in some other way, in Sweden or abroad.

The employment of doctoral students is regulated in the Swedish Code of Statues 1998: 80. Only those who are or have been admitted to PhD-studies may be appointed to doctoral studentships. When an appointment to a doctoral studentship is made, the ability of the student to benefit from PhD-studies shall primarily be taken into account. In addition to devoting themselves to their studies, those appointed to doctoral studentships may be required to work with educational tasks, research and administration, in accordance with specific regulations in the ordinance.

Type of employment
Limit of tenure, four years according to HF 5 kap 7§.

How to apply
Applications are to be submitted via the University’s recruitment system. The application should include a CV and a personal letter justifying your interest in the position and how it matches your qualifications. The application should also include a degree certificate or equivalent and any other document to which you would like to draw attention (copies of grade transcripts, details of referees, letters of recommendation, etc.).

Welcome to apply!

The Department of Clinical Sciences Lund is one of six departments at the Faculty of Medicine. Clinical Sciences Lund cooperates closely with Skåne University Hospital and the Faculty of Medicine in order to optimize the conditions for preclinical and clinical translational research, research strategies and development, as well as education on both undergraduate and postgraduate levels.

Type of employment Temporary position
Contract type Full time
First day of employment 2024-04-01 or upon agreement
Salary Monthly salary
Number of positions 1
Full-time equivalent 100
City Lund
County Skåne län
Country Sweden
Reference number PA2024/435
Contact
  • Mattias Belting, main supervisor, +4646178549
  • Anne Vähäniemi, HR-partner, +46462228758
Union representative
  • OFR/ST:Fackförbundet ST:s kansli, 046-2229362
  • SACO:Saco-s-rådet vid Lunds universitet, kansli@saco-s.lu.se
Last application date 05.Mar.2024 11:59 PM CET

Share links

Deadline: 2024-03-05 at 23:59
Unit: Health/Life sciences

Read the job description at the university homepage or apply.

Postdoctoral Researcher in Chromatin Biology of Immune Cells (scholarship)

Do you want to contribute to improving human health?

We are looking for an ambitious postdoctoral candidate that will contribute to advancing our understanding of how the oncoprotein MYC controls lymphocytes development through the regulation of topoisomerase activity, with the aim of developing strategies to hijacking MYC-driven lymphomas.

The project will be performed collaboratively between Laura Baranello Lab (Department of Cell and Molecular Biology) and Lisa Westerberg Lab (Department of Microbiology, Tumor and Cell Biology). The postdoctoral fellow will be located at Biomedicum, a top modern research building with a large repertoire of researchers and access to state-of-the-art infrastructure and facilities.

Our collaboration is at the intersection of chromatin biology, molecular immunology, and drug development aiming to reveal the molecular codes of cellular physiology and diseases.
The candidate will greatly benefit from this interdisciplinary environment, immersion in a highly stimulating and supportive research community, unique infrastructure, a buzzing capital, and scenic nature at your doorstep.

Your mission

The Baranello Lab – Drawing from our expertise in the fields of topoisomerase and cancer biology, we aim to answer fundamental questions about how transcription, replication and DNA topology are functionally coordinated in human cells. We use state-of-the-art approaches to assess transcriptomic, epigenomic and replisomic profiles, as well as advanced microscopy and drug screens to understand how topoisomerase regulation affects fundamental nuclear processes (key lab references: Baranello et al. Cell 2016; Wiegard et al. Molecular Cell 2021; Das et al. Molecular Cell 2022; Cameron et al. Science Advances 2023). The overall aim is to reveal novel cancer therapy targets and improved strategies for personalized treatment.

Recently we have identified a protein complex called “the topoisome” in which the oncoprotein MYC recruits and increases the catalytic activities of both Topoisomerase 1 and 2 to promote high transcriptional rates (Das et al. Molecular Cell 2022). The successful candidate will play a leading role in a full-time research project funded by the European Research Council Consolidator Grant, focused to address the key role of MYC-driven topoisome during B cells development. The outcome of this will inspire a new strategy to target MYC in lymphomas.
The project is a combination of practical laboratory tasks including master molecular biology, genomics, CRISPR-based genome editing, and computational analysis. The postdoc will plan and execute experiments, analyze data, interpret, and present the results, supervise students as well as write scientific articles, initially under partial supervision but with greater independence going forward.

We are a young and dynamic research team with a well-established collaborative network. The group is also associated to the laboratory of Dr. Levens at the National Institutes of Health (US) and Dr. Shiraige at Tokyo University (JP). The successful applicant will thus be part of multiple networks of recognized scientists.

Entry requirements

Scholarships for postdoctoral qualification can be established for foreign researchers who place their qualifications in Sweden. The purpose of scholarships for postdoctoral qualification is to promote internationalization and contribute to research qualification after a doctorate or equivalent. A scholarship for carrying out postdoctoral research can be granted for a maximum of two years within a four year period following the receipt of a doctoral degree or equivalent.

To be eligible for a postdoctoral scholarship, the person must have obtained a doctorate or a foreign degree deemed to be equivalent to a doctorate. Applicants who have not completed a doctorate at the end of the application period may also apply, provided that all requirements for a completed degree are met before the (intended) start date of the post doctoral education.

The head of the department determines whether their previous training and scholarly qualifications correspond to a Swedish doctorate or higher.

We are looking for a highly motivated, driven, enthusiastic person interested in our area of research, and ready to explore new avenues in science. The candidate should have a strong collaborative approach to research, be a team player as capable of performing tasks independently and contribute to a good social environment in the laboratory.

The candidate must have a PhD in medical sciences, molecular biology, molecular immunology, biochemistry or equivalent.

Requirements:

  • Strong expertise in cell and molecular biology
  • Expertise in genomics
  • Expertise in transcription regulation
  • Expertise in DNA topology
  • Proficiency in scientific programming (e.g., R/Bioconductor, Python, UNIX)
  • Interest in solving intricate scientific questions and willingness to help PhD/master students.
  • Excellent interpersonal and communication skills (in English written and verbal). Emphasis will be also placed on personal suitability, fitting well into the current research group. 

What do we offer?

The two labs are eager to provide the fellow with an opportunity to develop and/or apply state-of-the-art methodologies to solve timely biological key questions. Necessary training on sequencing technologies and computational analysis will be given to the fellow. We are eager to give the candidates opportunity to become fully independent researchers in interdisciplinary science within years.

Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. 

Visit Baranello Lab: https://ki.se/en/research/groups/topoisomerases-chromatin-biology-and-cancer-laura-baranellos-group

Visit Department of Cell and Molecular Biology: https://ki.se/en/cmb/department-of-cell-and-molecular-biology

Location: Stockholm Campus Solna

Type of scholarship

The amount is tax free and it is set for twelve months at a time, paid out on a six months basis. In exceptional cases, shorter periods may be acceptable.

Application process

An application must contain the following documents in English:

  • A complete curriculum vitae (max 3 pages)
  • A complete list of publications
  • A letter describing previous accomplishments, technical expertise and why you want to work with us (no more than one-page, generic letters not accepted)
  • Names and contact details of two scientists for reference letters

The application is to be submitted on the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2024-03-12 at 23:59
Unit: Forskargrupp Hartman

Read the job description at the university homepage or apply.

PhD fellowship in plasmid microbial ecology

The Department of Biology, Section of Microbiology invites applicants for a PhD fellowship in plasmid microbial ecology. The proposed position is affiliated with the project pTracker – Machine learning methods for data-driven discovery of antibiotic resistance plasmid dissemination and evolution, the project ROOT-MOBIL: Exploring the ROOT-MOBILOME: Horizontal Gene Transfer and Plasmid Dynamics in the Rhizosphere and the long-read sequencing research platform CoDoN – Copenhagen DNA Analysis Center, all granted by the Novo Nordisk Foundation. All these projects are unified under the objective of integrating various sequencing methodologies to get the maximum of (meta)-genomic information from complex communities and samples.

Start date is (expected to be) 1 August 2024 or as soon as possible thereafter.

The project

We are looking for a PhD student to join this project and participate notably with the isolation of high quality DNA from a variety of samples, preparation of various sequencing libraries type (WGS, metagenomic, HiC) for diverse sequencing platform: Illumina, PacBio, Oxford Nanopore. Metagenomic sequence assembly and annotation, linkage of mobile genetic with Metagenome Assembled Genomes (MAGs) in order to decipher plasmid-host networks in the rhizosphere

Effort will be made to implement DNA crosslinking protocols (HiC, meta3C) and single-cell encaspulation (microfluidic semi-permeable capsules; single-cell FACS) to soil samples. These methods combination will improve plasmid sequence assembly and link mobile genetic elements to their cellular host in complex environmental samples which is currently not achieved at a high-throuput.

The qualified candidate will primarily have hands-on experience in molecular biology, handling of high-molecular weight DNA and sequencing library preparation with different sequencing platforms. Previous experience with handling of (meta)-genomic data and associated bioinformatics tools is highly appreciated.

Who are we looking for?

We are looking for candidates within the field(s) of microbiology, microbial biotechnology, molecular biology or equivalent with research experience and a background in Microbiology. Applicants with the following proficiencies will be regarded highly qualified and will be prioritized: 

  • Experience with genome and plasmid sequencing, assembly and annotation from microbial isolates and shotgun metagenomics.
  • Experience on PacBio and/or Oxford Nanopore sequencing library preparation highly appreciated.
  • Knowledge on plasmid biology and research experience with long-reads sequencing technologies (PacBio, Oxford Nanopore) is highly desired.
  • Basic knowledge of command-line tools & UNIX environment highly appreciated.
  • Motivated to work in a multidisciplinary research team, as well as independently, with an open communication style and a problem-solving attitude.

 

Our group and research- and what do we offer?

The position is available at the Section of Microbiology, headed by Professor Søren Johannes Sørensen. The Section offers a highly diverse and inclusive environment consisting of ≈35 researchers that specialize in microbial community interactions, mobile genetic elements, horizontal gene transfer, and the early life human microbiome. The group has gained international reputation in applying a combination of bioinformatics and molecular biology approaches to address research questions of ecological, clinical, and biotechnological interest, which lie at the intersection of computational biology, genomics, and bacterial evolution.

The group is a part of the Department of Biology, Faculty of SCIENCE, University of Copenhagen. We are located in Copenhagen.

We offer creative and stimulating working conditions in dynamic and international research environment.

Principal supervisor is Professor Søren Sørensen (sjs@bio.ku.dk), Section of Microbiology, Department of Biology. The student will be co-supervised by Dr. Joseph Nesme (joseph.nesme@bio.ku.dk).

The PhD programme

Qualifications needed for the PhD programme
To be eligible for the PhD programme, you must have completed a degree programme, equivalent to a Danish master’s degree (180 ECTS/3 FTE BSc + 120 ECTS/2 FTE MSc) related to the subject area of the project, e.g. microbiology, microbial biotechnology, molecular biology or a closely related subject. For information of eligibility of completed programmes, see General assessments for specific countries and Assessment database.

Terms of employment in the PhD programme
Employment as PhD fellow is full time and for maximum 3 years.

Employment is conditional upon your successful enrolment as a PhD student at the PhD School at the Faculty of SCIENCE, University of Copenhagen. This requires submission and acceptance of an application for the specific project formulated by the applicant.

Terms of appointment and payment accord to the agreement between the Danish Ministry of Taxation and The Danish Confederation of Professional Associations on Academics in the State. The position is covered by the Protocol on Job Structure.

Responsibilities and tasks in the PhD programme

  • Carry through an independent research project under supervision
  • Complete PhD courses corresponding to approx. 30 ECTS / ½ FTE
  • Participate in active research environments, including a stay at another research institution, preferably abroad
  • Teaching and knowledge dissemination activities
  • Write scientific papers aimed at high-impact journals
  • Write and defend a PhD thesis on the basis of your project

 

We are looking for the following qualifications:

  • Professional qualifications relevant to the PhD project
  • Relevant publications
  • Relevant work experience
  • Other relevant professional activities
  • Curious mind-set with a strong interest in plasmid microbial ecology
  • Good language skills

 

***************************************************************************

Application and Assessment Procedure

 Your application including all attachments must be in English and submitted electronically by clicking APPLY NOW below.

Please include

  1. Motivated letter of application (max. one page)
  2. Curriculum vitae including information about your education, experience, language skills and other skills relevant for the position
  3. Original diplomas for Bachelor of Science or Master of Science and transcript of records in the original language, including an authorized English translation if issued in another language than English or Danish. If not completed, a certified/signed copy of a recent transcript of records or a written statement from the institution or supervisor is accepted.
  4. Publication list (if possible)
  5. Reference letters (if available)

Application deadline:

The deadline for applications is Tuesday 27 February 2024, 23:59 GMT +1.

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The further process
After deadline, a number of applicants will be selected for academic assessment by an unbiased expert assessor. You are notified, whether you will be passed for assessment.

The assessor will assess the qualifications and experience of the shortlisted applicants with respect to the above mentioned research area, techniques, skills and other requirements. The assessor will conclude whether each applicant is qualified and, if so, for which of the two models. The assessed applicants will have the opportunity to comment on their assessment. You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/.

 

Interviews with selected candidates are expected to be held in week early to mid May

Questions
For specific information about the PhD fellowship, please contact the principal supervisor or co-supervisor.

General information about PhD study at the Faculty of SCIENCE is available at the PhD School’s website: https://www.science.ku.dk/phd/.

The University of Copenhagen wishes to reflect the surrounding community and invites all regardless of personal background to apply for the position.

Deadline: 2024-02-27 at 23:59
Unit: Health/Life sciences

Read the job description at the university homepage or apply.

PhD-position at the Department of Biomedicine

PhD-position at the Department of Biomedicine

PhD-position at the Department of Biomedicine

UiB – Knowledge that shapes society

Through robust and close interaction with the world around us – globally, nationally and locally – we shall be instrumental in building a society based on knowledge, skills and attitudes.

Do you want to take part in shaping the future?

PhD position

At the Faculty of Medicine, Department of Biomedicine, a full-time PhD-position is available for a period of four (4) years. The positions include 25 % required duties such as teaching, exam work or supervision, depending on the demands at the department. The position is part of the project “The role of membrane protein modifications in age-related brain pathology”, funded by the Trond Mohn foundation and the University of Bergen.

About the project/work tasks:

The PhD candidate will, together with the group leader, have a central role in building up a new research group financed through the TMS starting grant. The group will study various molecular aspects of neuropathology, unified through a focus on membrane proteins. See more information on the research group’s website https://www.uib.no/en/rg/membrain

Qualifications and personal qualities:

Required qualifications:

  • Completed master’s degree or equivalent in biomedicine or molecular biology
  • Very good English skills, both written and spoken.

 

Required work experience/competence:

  • Master standard molecular biology and cell biology methods that are relevant to the research group.
  • Solid experience with CRISPR/Cas9-based modification of human cell cultures, this means the entire process from planning/gDNA design to identification of positive clones.
  • Experience with cultivation of patient-derived primary cells.
  • Experience with activation assay for cellular signaling.
  • Completed the course Laboratory Animal Sciences (LAS301/LAS302)

 

Desired work experience:

  • Experience from work with membrane proteins.
  • Experience with advanced confocal microscopy and image processing and analysis of microscopy images.
  • Experience with characterization of pathogenic protein variants.

 

Desired personal characteristics:

  • High learning capacity and curiosity and takes responsibility for own learning/progression.
  • Honest and with an ethical mindset suitable for research.
  • Introverted and positive, works well with others, accepts guidance in a good way.
  • Works independently and structured/planned and seeks help when necessary.
  • Able to deliver results to a defined deadline, such as article revisions.

About the PhD position (applies to university PhD positions):

Applicant whose education is from another country than Norway, need to also attach a certified translation of the diploma and transcript of grades to English or a Scandinavian language, if the original is not in any of these languages. It is also required that the applicant enclose a review from the Norwegian Directorate for Higher Education and Skills (HK-dir) whether the education (bachelor and master degree) in question is of a scope and level that corresponds to the level of a Norwegian master’s degree. Please see https://hkdir.no/en/ for more information about HK-dir’s general recognition. The review from HK-dir may take some time and the application should be sent to HK-dir as soon as you have decided to apply for the position. If no answer within the application deadline, you must enclose documentation from HK-dir that they have received your application. Please note that the automatic recognition offered by HK-dir is not sufficient, and will not be accepted as basis for admission to the PhD programme. Applicants with education from a Scandinavian country or medical degree from the EEA area and a license to practice medicine in Norway are exempt from the requirement for HK-dir assessment, see Admission requirements at the Faculty of Medicine | Faculty of Medicine | UiB

 

See documentation requirements for language qualifications: http://www.uib.no/en/med/115526/english-language-requirements-phd-admission

 

Organized research training (PhD program):

The candidate must take part in the University of Bergen approved PhD programme leading to the degree within a time limit of 3 years. You must have admission to the organized research training (PhD program) at the Faculty in order to qualify for the position. Application for admission to the PhD programme, including a project plan outline for the training plan must be submitted no later than three months after the date of commencement.

 

The PhD-position:

PhD-positions are fixed term positions. You cannot be employed in a PhD-position for more than one fixed term period at the same institution or have had similar employment at an institution in the region.

We can offer:

  • Exciting development opportunities as part of your role in a strong professional environment
  • Salary NOK 540 500 (code 1017, pay grade 55) in the state salary scale. For applicants with at least one year of employment in a position as a General Practitioner or Dentist, salary NOK 557 100 (code 1017, pay grade 57). Medical specialist starts on salary NOK 575 400 (code 1017, pay grade 59)
  • Enrolment in the Norwegian Public Service Pension Fund
  • Good welfare benefits

Your application must include:

  • A brief account of the applicant`s research interests and motivation for applying for the position
  • Certified copies of diplomas and transcripts of grades. Applicant whose education is from another country than Norway, need to also attach a certified translation of the diploma and transcript of grades to English or a Scandinavian language, if the original is not in any of these languages. It is also required that the applicant enclose a review from HK-dir (both bachelor and master degree) whether the education in question is of a scope and level that corresponds to the level of a Norwegian master’s degree. Please see https://hkdir.no/en/ for more information about HK-dir’s general recognition. This may take some time and we recommend you to apply as soon as you know you will apply for this position. If no answer within the application deadline, please enclose documentation from HK-dir that they have received your application
  • Documentation of language skills (English)
  • Complete list of publications and scientific work you want to be evaluated
  • Any publication in your name
  • Two references (name and contact information)

General information:

Detailed information about the position can be obtained by contacting: Researcher Henriette Aksnes, e-mail: henriette.aksnes@uib.no.

UiB must follow Norway’s export control regulations when processing applications for this position.

The state labour force shall reflect the diversity of Norwegian society to the greatest extent possible. People with immigrant backgrounds and people with disabilities are encouraged to apply for the position.

 

The University of Bergen applies the principle of public access to information when recruiting staff for academic positions.

Information about applicants may be made public even if the applicant has asked not to be named on the list of persons who have applied. The applicant must be notified if the request to be omitted is not met.

The successful applicant must comply with the guidelines that apply to the position at all times.

For further information about the recruitment process, click here.

Life as a PhD candidate at UiB

Marion Claireaux tells about life and work as a PhD candidate at UiB.

About UiB

The University of Bergen is a renowned educational and research institution, organised into seven faculties and approximately 54 institutes and academic centres. Campus is located in the centre of Bergen with university areas at Nygårdshøyden, Haukeland, Marineholmen, Møllendalsveien and Årstad. 

There are five departments and eight centres at Faculty of Medicine.

Read More about the faculty and departments.

 

Deadline: 2024-02-27 at 23:59
Unit: Health/Life sciences

Read the job description at the university homepage or apply.

Postdoctoral Researcher in Chromatin Biology of Immune Cells (time-limited employment)

Do you want to contribute to improving human health?

We are looking for an ambitious postdoctoral candidate that will work on advancing our understanding of how the oncoprotein MYC controls lymphocytes development through the regulation of topoisomerase activity, with the aim of developing strategies to hijacking MYC-driven lymphomas.

The project will be performed collaboratively between Laura Baranello Lab (Department of Cell and Molecular Biology) and Lisa Westerberg Lab (Department of Microbiology, Tumor and Cell Biology). The postdoctoral fellow will be located at Biomedicum, a top modern research building with a large repertoire of researchers and access to state-of-the-art infrastructure and facilities.

Our collaboration is at the intersection of chromatin biology, molecular immunology, and drug development aiming to reveal the molecular codes of cellular physiology and diseases. The candidate will greatly benefit from this interdisciplinary environment, immersion in a highly stimulating and supportive research community, unique infrastructure, a buzzing capital, and scenic nature at your doorstep.

Your mission

The Baranello Lab- Drawing from our expertise in the fields of topoisomerase and cancer biology, we aim to answer fundamental questions about how transcription, replication and DNA topology are functionally coordinated in human cells. We use state-of-the-art approaches to assess transcriptomic, epigenomic and replisomic profiles, as well as advanced microscopy and drug screens to understand how topoisomerase regulation affects fundamental nuclear processes (key lab references: Baranello et al. Cell 2016; Wiegard et al. Molecular Cell 2021; Das et al. Molecular Cell 2022; Cameron et al. Science Advances 2023). The overall aim is to reveal novel cancer therapy targets and improved strategies for personalized treatment.

Recently we have identified a protein complex called “the topoisome” in which the oncoprotein MYC recruits and increases the catalytic activities of both Topoisomerase 1 and 2 to promote high transcriptional rates (Das et al. Molecular Cell 2022). The successful candidate will play a leading role in a full-time research project funded by the European Research Council Consolidator Grant, focused to address the key role of MYC-driven topoisome during B cells development. The outcome of this work will inspire a new strategy to target MYC in lymphomas. The project is a combination of practical laboratory work including master molecular biology, genomics, CRISPR-based genome editing, and computational analysis. The postdoc will plan and execute experiments, analyze data, interpret, and present the results, supervise students as well as write scientific articles, initially under partial supervision but with greater independence going forward.

We are a young and dynamic research team with a well-established collaborative network. The group is also associated to the laboratory of Dr. Levens at the National Institutes of Health (US) and Dr. Shiraige at Tokyo University (JP). The successful applicant will thus be part of multiple networks of recognized scientists.

Your profile

To be eligible for employment as a postdoctor a doctoral degree or a foreign degree deemed to be equivalent to a doctoral degree is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. It is considered as an advantage if you have completed your doctoral degree within the last three years, if there are special reasons, your degree may have been completed earlier.

We are looking for a highly motivated, driven, enthusiastic person interested in our area of research, and ready to explore new avenues in science. The candidate should have a strong collaborative approach to research, be a team player as capable of working independently and contribute to a good social environment in the laboratory. The candidate must have a PhD in medical sciences, molecular biology, molecular immunology, biochemistry or equivalent.

Requirements:

  • Strong expertise in cell and molecular biology
  • Expertise in genomics
  • Expertise in transcription regulation
  • Expertise in DNA topology
  • Proficiency in scientific programming (e.g., R/Bioconductor, Python, UNIX)
  • Interest in solving intricate scientific questions and willingness to help PhD/master students.
  • Excellent interpersonal and communication skills (in English written and verbal). Emphasis will be also placed on personal suitability, fitting well into the current research group. 

What do we offer?

The two labs are eager to provide the fellow with an opportunity to develop and/or apply state-of-the-art methodologies to solve timely biological key questions. Necessary training on sequencing technologies and computational analysis will be given to the fellow. We are eager to give the candidates opportunity to become fully independent researchers in interdisciplinary science within years.

Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote better health for all. At Karolinska Institutet, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. Karolinska Institutet is a state university, which entitles you to several benefits through our collective agreement. Employees also have free access to our modern gym and receive reimbursements for medical care.

Visit Baranello Lab: https://ki.se/en/research/groups/topoisomerases-chromatin-biology-and-cancer-laura-baranellos-group

Visit Department of Cell and Molecular Biology: https://ki.se/en/cmb/department-of-cell-and-molecular-biology

Location: Stockholm, KI Campus Solna

[Video about a Karolinska Institutet, how we work towards “a better health for all”]

Application

An employment application must contain the following documents in English or Swedish:

  • A complete curriculum vitae (max 3 pages)
  • A complete list of publications
  • A letter describing previous accomplishments, technical expertise and why you want to work with us (no more than one-page, generic letters not accepted)
  • Names and contact details of two scientists for reference letters

The application is to be submitted through the Varbi recruitment system.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2024-03-12 at 23:59
Unit: Forskargrupp Hartman

Read the job description at the university homepage or apply.

Researcher with specialization in high-power amplifiers for particle accelerators

Published: 2024-02-13

Are you interested in working with solid-state power amplifiers, with the support of competent and friendly colleagues in an international environment? Are you looking for an employer that invests in sustainable employee development and offers safe, favourable working conditions? We welcome you to apply for a researcher position at Uppsala University.

Uppsala University is a comprehensive research-intensive university with a strong international standing. Our ultimate goal is to conduct education and research of the highest quality and relevance to make a long-term difference in society. Our most important assets are all the individuals whose curiosity and dedication make Uppsala University one of Sweden’s most exciting workplaces. Uppsala University has over 45,000 students, more than 7,000 employees and a turnover of around SEK 7 billion.

The Department of Physics and Astronomy is hosting the FREIA Division responsible for the FREIA Laboratory, where the research will be conducted. The research at FREIA gears towards future particle accelerators and instrumentation. The FREIA laboratory operates complex equipment such as superconducting cryostats and microwave equipment for developing and testing particle accelerator equipment. Current projects are connected to, for example, the European Spallation Source (ESS), MAX IV, the High Luminosity upgrade of the LHC at CERN. FREIA is also engaged in the development of free-electron lasers, and a compact X-ray laser and instrumentation in Uppsala, and in the development of RF high-power amplifiers based on solid state transistors for particle accelerators.

Project description

FREIA is collaborating with ESS on the design, development, construction and testing of a 400 kW solid state amplifier at 352 MHz, to replace the tetrode-based power stations which are currently installed at ESS to power the spoke cavity section of the accelerator. The successful candidate will contribute to our efforts in advancing the field of particle accelerators by taking part in the work with completing and characterizing the prototype RF power station in close collaboration with ESS staff.

Duties

  • Lead the design and experimental efforts in the fabrication, assembly, and testing of microwave solid-state power amplifiers with power levels from 1 kW per module to 20 kW and more per amplifier.
  • Analyze experimental data and contribute to the interpretation of results, leading to writing and publishing scientific contributions in highly ranked journals and conferences.
  • Develop high-efficiency microwave power amplifiers.
  • Develop low-loss high-power microwave combiners.
  • Conduct feasibility studies leading from a conceptual design to a final demonstrator.
  • Present findings at conferences, workshops, and seminars to share knowledge and engage with the global scientific community, and to enhance knowledge dissemination and societal engagement.
  • Contribute to the writing of proposals for research grants.

Requirements

Applicants must have a doctoral degree in physics or electrical engineering, or equivalent. We are looking for a person with a very good microwave engineering profile. The candidate should have a proven experience with the development of high-power solid-state power amplifiers and power combiners; hands on measurements of modules at kilowatt level and power amplifiers. The candidate must have experience with the use of a vector network analyzer (VNA), software for calculating EM-fields like HFSS, CST or similar. Very good oral and written proficiency in English, as well as the capacity to work both independently and in a team, are requirements. The work will partially take place at ESS in Lund, Sweden, wherefore frequent travel will be required.

Additional qualifications
A demonstrated ability to apply for and obtain research grants from external sources is a merit. 

About the employment
The employment is a permanent position (probationary period may be applied). Scope of employment 100 %. Starting date 2024-03-01 or as agreed. Placement: Uppsala.

For further information about the position, please contact:

Dragos Dancila, e-mail: dragos.dancila@angstrom.uu.se, phone +46 72 366 31 80.

Please submit your application by 26 February 2024, UFV-PA 2024/541.

Are you considering moving to Sweden to work at Uppsala University? Find out more about what it´s like to work and live in Sweden.

Uppsala University is a broad research university with a strong international position. The ultimate goal is to conduct education and research of the highest quality and relevance to make a difference in society. Our most important asset is all of our 7,600 employees and 53,000 students who, with curiosity and commitment, make Uppsala University one of Sweden’s most exciting workplaces.

Read more about our benefits and what it is like to work at Uppsala University
https://uu.se/om-uu/jobba-hos-oss/

Please do not send offers of recruitment or advertising services.

Submit your application through Uppsala University’s recruitment system.

Deadline: 2024-02-26 at 23:59
Unit: Health/Life sciences

Read the job description at the university homepage or apply.

Doctoral Researcher, The Presence of Classics in Early Modern Book History

The Faculty of Arts and MECANO MSCA Doctoral Network invite applications for a

 

Doctoral Researcher

 

to a fixed-term employment for 3 years, with the possibility of a one-year extension contract.

 

We invite applications for a dynamic and versatile PhD position titled “The Presence of Classics in Early Modern Book History”. This position is part of a vibrant and multidisciplinary research community focused on applying computational approaches to the study of large early modern data sources (especially British). We are seeking candidates who can, together with us, bridge the gap between humanities and data science and contribute to our exploration of conceptual change, intertextuality, and statistical analysis of knowledge production in history.

 

The aim of this PhD project is to study the reuse of Latin texts in Early Modern England. The Helsinki Computational History Group has used automated methods to detect all the instances of text reuse in the largest collections of printed data for British books (1470–1800, > 250.000 works) available in machine-readable form: Eighteenth Century Collections Online (ECCO), Early English Books Online (EEBO-tcp phase II) and British Library Newspapers. The result is a massive dataset of linked text-reuse fragments, which are qualified, clustered and compared. Based on this dataset, the project will focus on the text reuse of a selected group of Latin scientific authors such as Lucretius, Pliny the Elder, and Vitruvius, and their reception and reuse in Early modern works.

 

Host institution: University of Helsinki (Finland)

PhD programme:  PhD in Digital Humanities

Main supervisor: prof. Mikko Tolonen (University of Helsinki, Faculty of Arts, Digital Humanities)

Second supervisor: prof. Margherita Fantoli (KU Leuven, Faculty of Arts, Digital Humanities)

Mobility rule: has not resided in Finland for more than 12 months in the 36 months preceding appointment

 

Tasks of the PhD candidate:

• Completion of a PhD thesis within four years (1,0 fte, contract for three years, possibility for extension contract for fourth year);

• Participation in the general training programme of the doctoral network (kick-off, monthly online research meetings, annual workshops and schools, and final conference)

• Collaboration with a multidisciplinary research group focused on the intersection of computational science, linguistics, and history/cultural heritage.

• Active contribution to research on public discourse, conceptual change, and knowledge production.

• Use of computational approaches for the analysis of historical digital collections.

• Participation in joint publications and engagement in academic service.

 

Planned secondments: (1) Centre for Scientific Computing in Finland (CSC) (3 months): developing a subsetting tool to deal with noisy content; contributing to scripts for data processing, harmonisation, and modelling); (2) KU Leuven (6 months): fine-tuning the retrieval of Latin authors; studying textual features of Latin scientific and technical texts)

 

SELECTION CRITERIA

 

We believe in flexibility when selecting the ideal candidate; therefore, the below requirements are adaptable. You can approach this position from either (or both) of the following backgrounds:

 

Option 1: MA thesis in Classics, Early Modern Studies or Intellectual History

• A proven track record in use of computational approaches.

• Familiarity with Classics or early modern British data sources.

• Ability to conduct multidisciplinary research.

• Interest to connect different research communities.

 

Option 2: Computational Background

• MA / MPhil degree in Digital Humanities, Data Science, AI/NLP, Information Science, or related fields, held by time of appointment (if the degree is not yet obtained at the time of application, a statement by the applicant’s supervisor should confirm that it will be obtained by time of appointment).

• Demonstrated experience in applying computational methods.

• Capability to bridge the gap between data science and the humanities.

• Strong research and analytical skills.

 

This PhD position is part of a broader research community that includes different projects focusing on ECCO and EEBO sources, and which utilise historical full-text collections and large metadata collections in English, Latin and other languages. We are particularly interested in candidates who can enrich our understanding of the presence of classics in early modern book history.

 

Degree requirement for doctoral researcher position: The appointee must apply, and obtain, the right to pursue a doctoral degree at the University of Helsinki within the probationary period of 6 months: https://www.helsinki.fi/en/admissions-and-education/apply-doctoral-programmes/how-apply-doctoral-education

 

Applicants must not hold a doctoral degree in any other field or have failed a corresponding doctoral examination at another higher education institution.

 

The University of Helsinki is committed to promoting equality and preventing discrimination in all its operations. We welcome applicants from a variety of gender identities, linguistic and cultural backgrounds.

 

WHAT WE OFFER

 

The University of Helsinki offers the appointee a first-class research and teaching environment as well as the preconditions necessary for international cooperation (https://www.helsinki.fi/en/about-us/careers/why-university-helsinki).

 

The position is full-time for 3 years with a possible extension contract for fourth year. The employment contract will include a probationary period of six months.

 

The salary is competitive and complies with the MSC Work Programme: appr. 3550 €/month, including Mobility allowance, after compulsory deductions. A conditional Family allowance of appr. 500 € can be added to the salary.

 

For the possible fourth year extension contract the salary will be defined based on the demands level table for teaching and research personnel in the salary system of Finnish universities (approximately 3100-3700€/month, depending on the performance).

 

The University of Helsinki provides its staff with occupational health and sports services as well as professional development opportunities (https://www.helsinki.fi/en/about-us/careers/why-university-helsinki/staff-benefits). The appointee is expected to reside in Finland while employed by the University of Helsinki. International staff is supported in relocating to Finland (https://www.helsinki.fi/en/about-us/careers/welcome).

 

APPLICATION INSTRUCTIONS

 

The application must be submitted through the University of Helsinki electronic recruitment system by clicking on the link below. Employees of the University of Helsinki must submit their applications through the SAP Fiori portal.

 

Applicants are requested to enclose with their applications the following documents in English. Please add documents 1-4 as a single PDF file titled “lastname_firstname_application” and document 5 as a separate PDF file titled “lastname_firstname_writing_sample:

1. CV (max. 2 pages, including list of publications)

2. Cover letter (600–800 words), covering:

• Which qualifications make you suitable for the position

• How this PhD position aligns with your scholarly interests and further career plans within or outside academia

• Your motivation to participate in a doctoral network which includes international mobility and an internship period

3. Names and contact details (email address) of two academic referees

• You must have the permission of the academic referee to use their name and contact details. They may be asked to provide a reference letter at a later stage.

4. MA degree certificate (if available) and transcript of records

• If the degree is not yet obtained at the time of application, a statement by the applicant’s supervisor should confirm that it will be obtained by time of appointment

5. Academic writing sample in English (ca. 7000 words)

 

The deadline for applications is 15th of March 2024. Shortlisted applicants will be invited for an interview.

 

FURTHER INFORMATION

 

For any questions and further information, please contact Professor Mikko Tolonen, mikko.tolonen@helsinki.fi. Further information about the recruitment process can be obtained from HR Specialist Reeta Korhonen, reeta.korhonen@helsinki.fi.

 

 

 

This PhD position is part of MECANO: Mechanics of Canon Formation and the Transmission of Knowledge from Greco-Roman Antiquity (MSCA Doctoral Network). MECANO aims to advance the understanding of the mechanics of canon formation and knowledge transmission of ancient Greek and Latin texts. It will look at (a) how texts, ideas or authors become canonical by being cited, translated, studied, imitated, excerpted, or compiled by later authors, and (b) how such implicit canons have changed across time and space by being received in different cultural, intellectual and linguistic environments. To study the dynamics of canonicity from a longitudinal perspective, MECANO will combine qualitative approaches to intellectual history and reception studies with applications of digital and computational methods on extensive text corpora.

 

MSCA Doctoral Networks are research and training programmes with the goal of training highly skilled doctoral candidates, stimulate their creativity, enhance their innovation capacities and boost their employability in the long-term. For MECANO, this means responding to the need for historically conscious and digitally skilled Humanities PhDs and training the PhD candidates to tackle the challenges of modern engagement with the topics of canonicity, diversity, and cultural heritage.

 

Being part of an MSCA Doctoral Network means taking part in networking activities and spending time abroad. Each PhD candidate will be co-supervised by two academics within the consortium; they will be based at one of the universities of MECANO and visit the university of their co-supervisor for a research stay, as well as have a shorter internship at an associated partner. They will be expected to take full part in the training programme, consisting of summer schools, workshops, a regular online seminar, and other activities.

 

MECANO is committed to creating an environment in which all talents can develop to their maximum potential, regardless of gender, age, cultural origin, nationality or disability. We particularly encourage candidates from traditionally underrepresented groups to apply.

 

MECANO is advertising positions for 10 candidates within its framework, who will be based at 5 participating universities. Applications for each position must be submitted separately. It is possible to apply for more than one position, in which case the applicant must send a separate email to info@mecano-dn.eu, stating this and indicating their preference.

Do you have a helsinki.fi username and a valid employment contract, a grant researcher's contract, a visiting researcher's or visiting professor's contract at the University of Helsinki? Log in here to apply to our open positions.

Deadline: 2024-03-15 at 23:59
Unit: Health/Life sciences

Read the job description at the university homepage or apply.

Researcher

Ref PAR 2024/185

The Institute is composed of the following four departments:

  • The Department of Infectious Diseases
  • The Department of Microbiology and Immunology
  • The Department of Medical Biochemistry and Cell Biology
  • The Department of Laboratory Medicine

At present, the institute has about 340 employees and approximately 450 million SEK in total assets.

Duties 

Culture of primary cancer cells and cell-line cultures. Protein analytical techniques such as ELISA, Western blotting, molecular biological standard techniques such as qPCR, construction of luciferase assays etc. Histological techniques such as immunofluroescense, immunohistochemistry and confocal microscopy.

Qualifications 

PhD in a relevant subject.

Employment 

The employment is full time and temporary, 4 months, with placement at the Institute of Biomedicine. First day of employment as agreed.

Contact information for the post 

If you have any questions about the position, please contact Professor Martin Johansson. Phone: +46-736213802, e-mail: martin.e.johansson@gu.se

Unions 

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

Application 

To apply for a position at the University of Gothenburg, you have to create an account in our recruitment system. Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline. 

Applications must be received by: 2024-03-05

The application should contain:

  • Proof of completed PhD

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.

Deadline: 2024-03-05 at 23:59
Unit: Health/Life sciences

Read the job description at the university homepage or apply.

PhD student in Public Health Sciences (B)

The Department of Public Health sciences is a department at the Faculty of Social Sciences at Stockholm University, with around 70 employees. We offer a dynamic, interdisciplinary, and internationally leading research environment. The Department houses two research centres: Centre for Health Equity Studies (CHESS) and Centre for Social Research on Alcohol and Drugs (SoRAD). We offer education at the basic, advanced, and doctoral levels.

Project description 
The doctoral student’s dissertation work will be conducted within the project Mental health consequences following the loss of a family member during the Corona pandemic: A multi-methods approach. The project aims to evaluate the impact of bereavement on mental health using longitudinal data from Swedish nationwide total-population social and health registers. We will compare bereavement during the pandemic to before the pandemic, in different phases of the pandemic, bereavement due to COVID-19 to other causes of death, and in different population groups. A smaller part of the project will use qualitative interviews to explore and identify the pandemic-related circumstances and experiences of people bereaved during the pandemic that may have contributed to adverse mental health outcomes.

The thesis project should mainly be based on quantitative analyses of Swedish register data. However, a multi-methodological approach, where quantitative and qualitative methods are mixed, is encouraged.

For more information on the project see: Mental health consequences following the loss of a family member during the Corona pandemic

Qualification requirements
In order to meet the general entry requirements, the applicant must have either taken an advanced level academic degree, completed course demands for at least 240 higher education credits, of which at least 60 credits were taken at the advanced level, or in any other way within this country or abroad achieved substantially equivalent competence.  

In order to meet the specific entry requirements, the general syllabus for doctoral studies in the field of public health sciences stipulates that applicants must have good oral and written skills in English. Applicants must also have completed the course requirements concerning quantitative or qualitative methods relevant for Public Health Sciences comprising of at least 7.5 higher education credits at the advanced level.

The entry requirements can also be met if the applicant has acquired substantially equivalent knowledge either in Sweden or abroad. Whether such knowledge meets the specified requirements is decided upon by the Director of Studies for the doctoral programme in Public Health Sciences, and the final decision is made by the Head of Department.

The qualification requirements must be met by the deadline for applications.

Selection
The selection among the qualified applicants is based on their ability to achieve the goals for doctoral studies. The criteria used in this selection process are: 

  • Subject-specific knowledge of relevance to Public Health Sciences
  • Subject-specific knowledge of relevance to the research project to which the employment is linked (where applicable)
  • Independence in the analysis and planning of previous scholarly work
  • Scholarly stringency and quality of previous work and of the outline of the research plan
  • The ability to communicate and collaborate
  • The department’s possibilities to provide adequate supervision for the planned research.

Admission Regulations for Doctoral Studies at Stockholm University are available at: www.su.se/rules and regulations.

Terms of employment
Only a person who will be or has already been admitted to a third-cycle programme may be appointed to a doctoral studentship.

The term of the initial contract may not exceed one year. The employment may be extended for a maximum of two years at a time. However, the total period of employment may not exceed the equivalent of four years of full-time study.

Doctoral students should primarily devote themselves to their own education, but may engage in teaching, research, and administration corresponding to a maximum of 20 % of a full-time position.

Please note that admission decisions cannot be appealed.

Stockholm University strives to be a workplace free from discrimination and with equal opportunities for all.

Contact
For more information, please contact Professor Mikael Rostila, telephone: +46 8 16 44 16, mikael.rostila@su.se.

For more information about the doctoral programme, please contact the Director of Studies Sara Brolin Låftman, sara.brolin.laftman@su.se.

Union representatives
Ingrid Lander (Saco-S), telephone: +46 708 16 26 64, saco@saco.su.se, Alejandra Pizarro Carrasco (Fackförbundet ST/OFR), telephone: +46 8 16 34 89, alejandra@st.su.se, seko@seko.su.se (SEKO), and PhD student representative, doktorandombud@sus.se.

Application
Apply for the PhD student position at Stockholm University’s recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline.

Please include the following information with your application

  • Your contact details and personal data
  • Your highest degree
  • Your language skills
  • Contact details for 2–3 references

and, in addition, please include the following documents

  • Cover letter
  • CV – degrees and other completed courses, work experience and a list of degree projects/theses
  • An outline that describes the planned research (1-3 pages). This must, where applicable, be linked to the call’s project description. The outline must indicate the main focus, conceivable thesis topic, and preferably also a specification of a possible research problem, theory, method and material.
  • Degree certificates and grades confirming that you meet the general and specific entry requirements (no more than 6 files)
  • Letters of recommendation (no more than 6 files)
  • Degree projects/theses (no more than 6 files).

The instructions for applicants are available at: How to apply for a position.

You are welcome to apply!

Stockholm University contributes to the development of sustainable democratic society through knowledge, enlightenment and the pursuit of truth.

Deadline: 2024-03-15 at 23:59
Unit: Health/Life sciences

Read the job description at the university homepage or apply.

Researcher

Ref PAR 2024/187

The goal of our research group is to understand how inflammatory processes are regulated and what role the so-called G protein-coupled receptors play in this regulation, when it works well and when the balance is disrupted which leads to inflammatory diseases. 

Duties 

Basic cell biology and receptor pharmacology techniques will be used to analyze both blood and tissue neutrophils. The focus will be on signaling, priming status, degranulation, and secretion as well as activation of neutrophils in order to identify and validate significant differences between neutrophils and neutrophil markers from healthy donors and patients with inflammatory disease. The job assignments include several laboratory techniques to study neutrophils and neutrophil markers. At the signaling level, these methods include HTRF-based cAMP assay, activation of various G-protein subtypes, β-arrestin translocation, and cytosolic calcium changes. The most important neutrophil functions that will be studied include migration (chemotaxis), phagocytosis, endocytosis, degranulation, activation of the NADPH oxidase for production of reactive oxygen species and apoptosis/necrosis. The laboratory work will also involve cell culture, subcellular fractionation, flow cytometry, ELISA and SDS-PAGE/western blot. In addition to the laboratory work, the job assignments include to compile the obtained results so that these can be presented in both visual and written forms, as well as supervision of students in the research group. 

Qualifications 

The applicant should hold a PhD in the subject of biochemistry, molecular biology, or cell biology. Hands-on experience in working with phagocytes, reactive oxygen metabolites and receptor pharmacology with a focus on G protein-coupled receptors is a requirement. Hands-on experience with microscopy (confocal and total internal reflection fluorescence [TIRF] microscopes) and cell culture is an advantage. The candidate is expected to be active in the design and implementation of his/her projects, as well as to collaborate closely with other members of the team and with other groups. Good communication skills, excellent scientific English in both speech and writing are requirements. Great emphasis will be placed on personal suitability and personal qualities such as being initiative-taking, flexible, quality-conscious, structured, loyal, and having good cooperation skills will be highly valued.

Employment 

Type of employment: Fixed-term employment, 11 months
Extent: 100 %
Location: Institute of Medicine, Gothenburg
First day of employment: According to agreement

Contact information for the post 

Huamei Forsman
Adjunct Professor
+46(0)70-8701899
huamei.forsman@gu.se

Martina Sundqvist
Researcher
+46(0)70-8173612
martina.sundqvist@rheuma.gu.se

Helena Forsblad D’elia
Professor/Head of Department 
+46(0)76-1103883
helena.forsblad@rheuma.gu.se  

Unions 

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande 

Application 

To apply for a position at the University of Gothenburg, you have to create an account in our recruitment system. Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline. 

Please enlose PhD certificate with the application.

Applications must be received by: 2024-03-05

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.

Deadline: 2024-03-05 at 23:59
Unit: Health/Life sciences

Read the job description at the university homepage or apply.

PhD doctoral position examining long non-coding RNA function within fat cells

Do you want to contribute to top quality medical research?

To be a doctoral student means to devote oneself to a research project under supervision of experienced researchers and following an individual study plan. For a doctoral degree, the equivalent of four years of full-time doctoral education is required.

The research group

The adipocyte expresses over 4000 long non-coding RNAs (lncRNAs), many uniquely expressed in fat cells. However, how these polymeric molecules function in concert with the metabolic machinery of the cell is not well understood. In our laboratory, we investigate how lncRNAs adapt the adipocyte for specialised function, specifically in the context of lipid droplet metabolism. Our investigation focuses on lncRNAs that may underline compromised metabolic flexibility and contribute to cardiometabolic disease pathogenesis.

We integrate findings from well-characterized human white adipose tissue (WAT) biopsies and large population genetics to identify lncRNAs implicated in lipid metabolism and cardiometabolic disease. The disease-associated lncRNAs are investigated in human adipocyte cell models and using CRISPRi/a gene perturbation coupled to lipidomic/metabolomics, we aim to understand the effect of the lncRNA expression on adipocyte metabolism. In addition, we use gene variant editing in human adipocytes to understand how single nucleotide polymorphisms located in lncRNA gene loci lead to alterations in lipid droplet metabolism.

Our research group is based in the Unit of Endocrinology at the Department of Medicine-Huddinge. The group is expanding, and we will aim to hire additional PhD and Postdoctoral researchers, which will be advertised this year. The group interacts with the other research groups in the Unit of Endocrinology, including sharing lab space and lab meetings creating a dynamic and diverse research space that fosters collaboration on multiple projects. Please see the lab website for further details.   

Long noncoding RNA in the adipocyte – Alastair Kerr Research Group

The doctoral student project and the duties of the doctoral student

This doctoral project will explore how lncRNAs regulate lipid breakdown and in turn type-2 diabetes pathogenesis. The student will use omics and white adipose tissue clinical phenotype data to uncover novel lncRNAs associated to lipid breakdown. The student will progress these lncRNAs into molecular studies in human adipocytes, where they will use advanced molecular gene perturbation systems and in-house developed molecular methodology to uncover how these lncRNAs function at a molecular resolution. The doctoral student will be trained in how to examine clinical data to identify candidate lncRNAs and develop an investigational pipeline to understand how they function. The student will be involved in learning from current lab members and teaching future lab members that will be hired.  

What do we offer?

A creative and inspiring environment full of expertise and curiosity. Karolinska Institutet is one of the world’s leading medical universities. Our vision is to pursue the development of knowledge about life and to promote a better health for all. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. As a doctoral student you are offered an individual research project, a well-educated supervisor, a vast range of elective courses and the opportunity to work in a leading research group. Karolinska Institutet collaborates with prominent universities from all around the world, which ensures opportunities for international exchanges. You will be employed on a doctoral studentship which means that you receive a contractual salary. Employees also have access to our modern gym for free and receive reimbursements for medical care.

Eligibility requirements for doctoral education

In order to participate in the selection for a doctoral position, you must meet the following general (A) and specific (B) eligibility requirements at latest by the application deadline.

It is your responsibility to certify eligibility by following the instructions on the web page Entry requirements (eligibility) for doctoral education.

A) General eligibility requirement

You meet the general eligibility requirement for doctoral/third-cycle/PhD education if you:

  1. have been awarded a second-cycle/advanced/master qualification (i.e. master degree), or
  2. have satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the advanced/second-cycle/master level, or
  3. have acquired substantially equivalent knowledge in some other way in Sweden or abroad.*

Follow the instructions on the web page Entry requirements (eligibility) for doctoral education.

*If you claim equivalent knowledge, follow the instructions on the web page Assessing equivalent knowledge for general eligibility for doctoral education.

 

B) Specific eligibility requirement

You meet the specific eligibility requirement for doctoral/third-cycle/PhD education if you:

– Show proficiency in English equivalent to the course English B/English 6 at Swedish upper secondary school.

Follow the instructions on the web page English language requirements for doctoral education.

Verification of your documents Karolinska Institutet checks the authenticity of your documents. Karolinska Institutet reserves the right to revoke admission if supporting documents are discovered to be fraudulent. Submission of false documents is a violation of Swedish law and is considered grounds for legal action.

(A) and (B) can only be certified by the documentation requirement for doctoral education.

Skills and personal qualities

Required

  • The chosen candidate will have completed a Master’s degree in biology/Cell Biology/Molecular Biology/Biochemistry or another related subject and completed a wet laboratory based thesis project.
  • A good knowledge of cell biology.
  • Clear communication and documentation skills to be able to explain and replicate research findings. 
  • An ability to work independently.  

Desirable

  • Experience in cell culture as well as basic molecular biology techniques eg. Western blot analyses, qRT-PCR and similar methodology is highly advantageous.
  • Documented skills in teaching practices.
  • Experience in RNA biology.
  • Experience in microscopy.

Terms and conditions

The doctoral student will be employed on a doctoral studentship maximum 4 years full-time.

Application process

Submit your application and supporting documents through the Varbi recruitment system. Use the button in the top right corner and follow the instructions. We prefer that your application is written in English, but you can also apply in Swedish.

Your application must contain the following documents:

– A personal letter and a curriculum vitae
– Degree projects and previous publications, if any
– Any other documentation showing the desirable skills and personal qualities described above
– Documents certifying your general eligibility (see A above)
– Documents certifying your specific eligibility (see B above)

Selection

A selection will be made among eligible applicants on the basis of the ability to benefit from doctoral education. The qualifications of the applicants will be evaluated on an overall basis.

Karolinska Institutet uses the following bases of assessment:

– Documented subject knowledge of relevance to the area of research
– Analytical skill
– Other documented knowledge or experience that may be relevant to doctoral studies in the subject.

All applicants will be informed when the recruitment is completed.

Want to make a difference? Join us and contribute to better health for all

Deadline: 2024-03-07 at 23:59
Unit: Forskargrupp Hartman

Read the job description at the university homepage or apply.